(Q36229012)

12 August 2017

Chromosomal reinsertion of broken RSS ends during T cell development (English)

1 reference

12 August 2017

4

Jayne S Danska

1 reference

12 August 2017

John D Curry

1

1 reference

12 August 2017

Danae Schulz

2

1 reference

12 August 2017

Cynthia J Guidos

3

1 reference

12 August 2017

Lauryl Nutter

5

1 reference

12 August 2017

Andre Nussenzweig

6

1 reference

12 August 2017

Mark S Schlissel

7

1 reference

12 August 2017

language of work or name

English

0 references

publication date

4 September 2007

1 reference

Journal of Experimental Medicine

12 August 2017

1 reference

12 August 2017

204

1 reference

12 August 2017

10

1 reference

12 August 2017

2293-2303

1 reference

In vivo reinsertion of excised episomes by the V(D)J recombinase: a potential threat to genomic stability

12 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118463

Mutations of Bacteria from Virus Sensitivity to Virus Resistance

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118463

Risk of non-Hodgkin lymphoma (NHL) in relation to germline variation in DNA repair and related genes

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118463

ATM stabilizes DNA double-strand-break complexes during V(D)J recombination.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118463

Recombinase, chromosomal translocations and lymphoid neoplasia: targeting mistakes and repair failures

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118463

Genomic instability due to V(D)J recombination-associated transposition.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118463

Genetic and epigenetic regulation of IgH gene assembly

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118463

A direct interaction between the RAG2 C terminus and the core histones is required for efficient V(D)J recombination

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118463

Quantification of Jkappa signal end breaks in developing B cells by blunt-end linker ligation and qPCR.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118463

The taming of a transposon: V(D)J recombination and the immune system

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118463

A non-B-DNA structure at the Bcl-2 major breakpoint region is cleaved by the RAG complex

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118463

Full-length RAG-2, and Not Full-length RAG-1, Specifically Suppresses RAG-mediated Transposition but Not Hybrid Joint Formation or Disintegration

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118463

Restraining the V(D)J recombinase

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118463

The role of DNA breaks in genomic instability and tumorigenesis

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118463

The C-terminal portion of RAG2 protects against transposition in vitro

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118463

Regulation of RAG1/RAG2-mediated transposition by GTP and the C-terminal region of RAG2

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118463

p53 Binding protein 53BP1 is required for DNA damage responses and tumor suppression in mice

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118463

In vivo transposition mediated by V(D)J recombinase in human T lymphocytes

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118463

Prospective estimation of recombination signal efficiency and identification of functional cryptic signals in the genome by statistical modeling

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118463

A small molecule Abl kinase inhibitor induces differentiation of Abelson virus-transformed pre-B cell lines

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118463

The "dispensable" portion of RAG2 is necessary for efficient V-to-DJ rearrangement during B and T cell development

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118463

V(D)J recombination: RAG proteins, repair factors, and regulation

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118463

Genomic instability in mice lacking histone H2AX

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118463

Restrictions limiting the generation of DNA double strand breaks during chromosomal V(D)J recombination

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118463

Increased accumulation of hybrid V(D)J joins in cells expressing truncated versus full-length RAGs.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118463

Mechanisms of chromosomal translocations in B cell lymphomas

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118463

Analysis of the V(D)J recombination efficiency at lymphoid chromosomal translocation breakpoints

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118463

Signal joint formation is also impaired in DNA-dependent protein kinase catalytic subunit knockout cells

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118463

Transposition mediated by RAG1 and RAG2 and its implications for the evolution of the immune system

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118463

The origins of V(D)J recombination

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118463

Targeted disruption of ATM leads to growth retardation, chromosomal fragmentation during meiosis, immune defects, and thymic lymphoma

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118463

Restoration of T cell development in RAG-2-deficient mice by functional TCR transgenes.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118463

RAG-1 and RAG-2, adjacent genes that synergistically activate V(D)J recombination

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118463

RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118463

DNA transposition by the RAG1 and RAG2 proteins: a possible source of oncogenic translocations

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118463

Rearrangement of antigen receptor genes is defective in mice with severe combined immune deficiency.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118463

Leukemia and lymphoma: a cost of doing business for adaptive immunity

29 June 2018

1 reference

Crossref

https://api.crossref.org/works/10.1084%2FJEM.20070583

V(D)J recombination activates a p53-dependent DNA damage checkpoint in scid lymphocyte precursors.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1084%2FJEM.20070583

V(D)J recombinase mediated inter-chromosomal HPRT alterations at cryptic recombination signal sequences in peripheral human T cells.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118463

Novel strand exchanges in V(D)J recombination

22 September 2018

1 reference

12 December 2020

Spatial proximity of translocation-prone gene loci in human lymphomas

1 reference

12 December 2020

RAG1/2-mediated resolution of transposition intermediates: two pathways and possible consequences

1 reference

12 December 2020

The V(D)J recombinase efficiently cleaves and transposes signal joints

1 reference

12 December 2020

Identifiers

DOI

10.1084/JEM.20070583

1 reference

12 August 2017

1 reference

12 August 2017

PubMed publication ID

17785508

1 reference