(Q36602690)

15 August 2017

1 reference

title

Apoptotic cascades as possible targets for inhibiting cell death in Huntington's disease (English)

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15 August 2017

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2

Mark R Kotter

1 reference

15 August 2017

Lindsay R Pattison

1

1 reference

PubMed ID

16998646

15 August 2017

Dean Fraga

series ordinal

3

1 reference

PubMed ID

16998646

15 August 2017

Raphael M Bonelli

series ordinal

4

1 reference

15 August 2017

22 September 2006

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15 August 2017

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15 August 2017

253

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15 August 2017

9

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15 August 2017

1137-1142

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https://scigraph.springernature.com/pub.10.1007/s00415-006-0198-8

15 August 2017

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cites work

Minocycline for Huntington's disease: an open label study

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS00415-006-0198-8

The changing landscape of ischaemic brain injury mechanisms.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS00415-006-0198-8

Minocycline inhibits microglial activation and protects nigral cells after 6-hydroxydopamine injection into mouse striatum

21 January 2018

1 reference

12 December 2020

Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked

1 reference

12 December 2020

Minocycline inhibits cytochrome c release and delays progression of amyotrophic lateral sclerosis in mice

1 reference

12 December 2020

Caspase cleavage of mutant huntingtin precedes neurodegeneration in Huntington's disease.

1 reference

12 December 2020

Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta

1 reference

12 December 2020

Loss of huntingtin-mediated BDNF gene transcription in Huntington's disease

1 reference

12 December 2020

Minocycline slows progress of Huntington's disease in mice

1 reference

12 December 2020

Ordering the cytochrome c-initiated caspase cascade: hierarchical activation of caspases-2, -3, -6, -7, -8, and -10 in a caspase-9-dependent manner

1 reference

12 December 2020

Minocycline inhibits caspase-1 and caspase-3 expression and delays mortality in a transgenic mouse model of Huntington disease

1 reference

12 December 2020

The likelihood of being affected with Huntington disease by a particular age, for a specific CAG size

1 reference

12 December 2020

Pathobiology of ischaemic stroke: an integrated view

1 reference

12 December 2020

Huntingtin acts in the nucleus to induce apoptosis but death does not correlate with the formation of intranuclear inclusions.

1 reference

12 December 2020

Increased apoptosis and early embryonic lethality in mice nullizygous for the Huntington's disease gene homologue

1 reference

12 December 2020

Ancestral differences in the distribution of the delta 2642 glutamic acid polymorphism is associated with varying CAG repeat lengths on normal chromosomes: insights into the genetic evolution of Huntington disease

1 reference

12 December 2020

Trinucleotide repeat elongation in the Huntingtin gene in Huntington disease patients from 71 Danish families

1 reference

12 December 2020

Evidence for a preferential loss of enkephalin immunoreactivity in the external globus pallidus in low grade Huntington's disease using high resolution image analysis

1 reference

12 December 2020

Control of apoptosis by proteases

1 reference

12 December 2020

Huntingtin is present in the nucleus, interacts with the transcriptional corepressor C-terminal binding protein, and represses transcription

1 reference

12 December 2020

The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis

1 reference

12 December 2020

Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

1 reference

12 December 2020

Glutamine repeats as polar zippers: their possible role in inherited neurodegenerative diseases

1 reference

12 December 2020

Apoptosis and caspases in neurodegenerative diseases

1 reference

12 December 2020

A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes.

1 reference

12 December 2020

A tetracycline derivative, minocycline, reduces inflammation and protects against focal cerebral ischemia with a wide therapeutic window

1 reference

12 December 2020

Neuropathological classification of Huntington's disease

1 reference

12 December 2020

Modeling Huntington's disease in cells, flies, and mice

1 reference

12 December 2020

1 reference

12 December 2020

Huntington's disease: how does huntingtin, an anti-apoptotic protein, become toxic?

1 reference

12 December 2020

Genetic polymorphisms adjacent to the CAG repeat influence clinical features at onset in Huntington's disease

1 reference

12 December 2020

Brain inflammation in Alzheimer disease and the therapeutic implications

1 reference

12 December 2020

Interleukin-1 beta converting enzyme requires oligomerization for activity of processed forms in vivo

1 reference

12 December 2020

Caspase and calpain substrates: roles in synaptic plasticity and cell death

1 reference

12 December 2020

Huntingtin's WW domain partners in Huntington's disease post-mortem brain fulfill genetic criteria for direct involvement in Huntington's disease pathogenesis

1 reference

12 December 2020

Aging, energy, and oxidative stress in neurodegenerative diseases.

1 reference

12 December 2020

A YAC mouse model for Huntington's disease with full-length mutant huntingtin, cytoplasmic toxicity, and selective striatal neurodegeneration.

1 reference

12 December 2020

Potential mechanisms of interleukin-1 involvement in cerebral ischaemia.

1 reference

12 December 2020

Molecular ordering of the Fas-apoptotic pathway: the Fas/APO-1 protease Mch5 is a CrmA-inhibitable protease that activates multiple Ced-3/ICE-like cysteine proteases

1 reference

12 December 2020

Inflammatory mediators and stroke: new opportunities for novel therapeutics

1 reference

12 December 2020

Fas and Fas ligand expression in Alzheimer's disease.

1 reference

12 December 2020

Mechanisms for neuronal cell death and dysfunction in Huntington's disease: pathological cross-talk between the nucleus and the mitochondria?

1 reference

12 December 2020

Key issues in Alzheimer's disease inflammation

1 reference

12 December 2020

Minocycline, a tetracycline derivative, is neuroprotective against excitotoxicity by inhibiting activation and proliferation of microglia.

1 reference

12 December 2020

Developmental cell death: morphological diversity and multiple mechanisms

1 reference

12 December 2020

Cytokines and their receptors in the central nervous system: physiology, pharmacology, and pathology

1 reference

12 December 2020

Bacterial and yeast chaperones reduce both aggregate formation and cell death in mammalian cell models of Huntington's disease

1 reference

12 December 2020

Apoptosis in Huntington's disease.

1 reference

12 December 2020

Phagocytosis in the developing CNS: more than clearing the corpses

1 reference

12 December 2020

Neuroprotection in Huntington's disease: a 2-year study on minocycline

1 reference

12 December 2020

Tetracyclines inhibit microglial activation and are neuroprotective in global brain ischemia

1 reference

12 December 2020

Peptides containing glutamine repeats as substrates for transglutaminase-catalyzed cross-linking: relevance to diseases of the nervous system

1 reference

12 December 2020

10.1007/S00415-006-0198-8

Identifiers

DOI

1 reference

15 August 2017

1 reference

PubMed ID

16998646