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Probing mechanisms that underlie human neurodegenerative diseases in Drosophila
scientific article published on 4 September 2012
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3663445
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13 February 2020
title
Probing mechanisms that underlie human neurodegenerative diseases in Drosophila
(English)
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stated in
Europe PubMed Central
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3663445
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13 February 2020
main subject
Drosophila
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neurodegeneration
1 reference
based on heuristic
inferred from title
author
Manish Jaiswal
series ordinal
1
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3663445
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13 February 2020
Hector Sandoval
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2
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13 February 2020
Vafa Bayat
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4
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13 February 2020
Hugo J. Bellen
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5
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13 February 2020
author name string
K Zhang
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3
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13 February 2020
publication date
4 September 2012
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13 February 2020
published in
Annual Review of Genetics
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3663445
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13 February 2020
volume
46
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13 February 2020
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371-396
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13 February 2020
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29 September 2017
NAD synthase NMNAT acts as a chaperone to protect against neurodegeneration.
1 reference
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29 September 2017
Genetic dissection of neural circuits
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29 September 2017
Neuropathy target esterase gene mutations cause motor neuron disease
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29 September 2017
TDP-43 mutations in familial and sporadic amyotrophic lateral sclerosis
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29 September 2017
A Drosophila model for LRRK2-linked parkinsonism
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29 September 2017
Neuropathology in Drosophila mutants with increased seizure susceptibility
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29 September 2017
The PINK1/Parkin pathway regulates mitochondrial morphology
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29 September 2017
Suppression of neurodegeneration and increased neurotransmission caused by expanded full-length huntingtin accumulating in the cytoplasm
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29 September 2017
Reduced mitochondrial SOD displays mortality characteristics reminiscent of natural aging
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29 September 2017
Atg7-dependent autophagy promotes neuronal health, stress tolerance, and longevity but is dispensable for metamorphosis in Drosophila.
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29 September 2017
Autophagy, amyloidogenesis and Alzheimer disease
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29 September 2017
Lifetime risk of stroke and dementia: current concepts, and estimates from the Framingham Study
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29 September 2017
Genome-wide screen for modifiers of ataxin-3 neurodegeneration in Drosophila
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29 September 2017
hVAPB, the causative gene of a heterogeneous group of motor neuron diseases in humans, is functionally interchangeable with its Drosophila homologue DVAP-33A at the neuromuscular junction
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29 September 2017
Transgenesis upgrades for Drosophila melanogaster.
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29 September 2017
Motor neuron disease-associated mutant vesicle-associated membrane protein-associated protein (VAP) B recruits wild-type VAPs into endoplasmic reticulum-derived tubular aggregates.
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29 September 2017
DJ-1 gene deletion reveals that DJ-1 is an atypical peroxiredoxin-like peroxidase
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29 September 2017
Inhibitors of metabolism rescue cell death in Huntington's disease models.
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29 September 2017
ESCRT-III dysfunction causes autophagosome accumulation and neurodegeneration
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29 September 2017
HDAC6 rescues neurodegeneration and provides an essential link between autophagy and the UPS
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29 September 2017
Phototransduction and retinal degeneration in Drosophila.
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29 September 2017
Trinucleotide Repeat Disorders
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29 September 2017
Oxidative stress mediates tau-induced neurodegeneration in Drosophila
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29 September 2017
Drosophila NMNAT maintains neural integrity independent of its NAD synthesis activity
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29 September 2017
Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases
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29 September 2017
The roles of intracellular protein-degradation pathways in neurodegeneration
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29 September 2017
Oxidative damage in Huntington's disease pathogenesis
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29 September 2017
ALS: a disease of motor neurons and their nonneuronal neighbors
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29 September 2017
wasted away, a Drosophila mutation in triosephosphate isomerase, causes paralysis, neurodegeneration, and early death
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29 September 2017
Drosophila model of human inherited triosephosphate isomerase deficiency glycolytic enzymopathy
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29 September 2017
ALS phenotypes with mutations in CHMP2B (charged multivesicular body protein 2B)
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29 September 2017
Alzheimer's disease pathogenesis: role of aging
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29 September 2017
Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin
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29 September 2017
Glial cell inclusions and the pathogenesis of neurodegenerative diseases
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29 September 2017
BEHAVIORAL MUTANTS OF Drosophila ISOLATED BY COUNTERCURRENT DISTRIBUTION
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29 September 2017
Lessons from Drosophila models of DJ-1 deficiency
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29 September 2017
Mutations in the endosomal ESCRTIII-complex subunit CHMP2B in frontotemporal dementia
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29 September 2017
Mitochondrial localization of the Parkinson's disease related protein DJ-1: implications for pathogenesis
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3663445
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29 September 2017
Intraneuronal Abeta, non-amyloid aggregates and neurodegeneration in a Drosophila model of Alzheimer's disease.
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29 September 2017
Loss of Swiss cheese/neuropathy target esterase activity causes disruption of phosphatidylcholine homeostasis and neuronal and glial death in adult Drosophila
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29 September 2017
Emerging technologies for gene manipulation in Drosophila melanogaster
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29 September 2017
Twenty years of the Alzheimer's disease amyloid hypothesis: a genetic perspective
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29 September 2017
Identification of combinatorial drug regimens for treatment of Huntington's disease using Drosophila.
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29 September 2017
Mutations in LRRK2 cause autosomal-dominant parkinsonism with pleomorphic pathology
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3663445
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29 September 2017
A mutation in the vesicle-trafficking protein VAPB causes late-onset spinal muscular atrophy and amyotrophic lateral sclerosis
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3663445
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29 September 2017
Increased nuclear NAD biosynthesis and SIRT1 activation prevent axonal degeneration
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PubMed Central
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29 September 2017
Mutations in the Na+/K+ -ATPase alpha3 gene ATP1A3 are associated with rapid-onset dystonia parkinsonism
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29 September 2017
Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3663445
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29 September 2017
Hereditary early-onset Parkinson's disease caused by mutations in PINK1
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3663445
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29 September 2017
Drosophila parkin mutants have decreased mass and cell size and increased sensitivity to oxygen radical stress
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3663445
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29 September 2017
Dissecting the pathological effects of human Abeta40 and Abeta42 in Drosophila: a potential model for Alzheimer's disease
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29 September 2017
Brain-specific deletion of neuropathy target esterase/swisscheese results in neurodegeneration
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PubMed Central
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29 September 2017
Cytoplasmic aggregates trap polyglutamine-containing proteins and block axonal transport in a Drosophila model of Huntington's disease.
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3663445
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29 September 2017
Aging: a theory based on free radical and radiation chemistry
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29 September 2017
Interaction of Akt-phosphorylated ataxin-1 with 14-3-3 mediates neurodegeneration in spinocerebellar ataxia type 1.
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29 September 2017
Mitochondrial pathology and apoptotic muscle degeneration in Drosophila parkin mutants
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29 September 2017
Deregulation of the Egfr/Ras signaling pathway induces age-related brain degeneration in the Drosophila mutant vap.
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29 September 2017
Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3663445
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29 September 2017
Drosophila VAP-33A directs bouton formation at neuromuscular junctions in a dosage-dependent manner
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3663445
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29 September 2017
Temperature-sensitive paralytic mutants are enriched for those causing neurodegeneration in Drosophila.
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29 September 2017
The molecular basis of mucolipidosis type IV.
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29 September 2017
Early mitochondrial calcium defects in Huntington's disease are a direct effect of polyglutamines.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3663445
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29 September 2017
Chronic systemic pesticide exposure reproduces features of Parkinson's disease
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3663445
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29 September 2017
Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3663445
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29 September 2017
A Drosophila model of Parkinson's disease
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3663445
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29 September 2017
stress sensitive B encodes an adenine nucleotide translocase in Drosophila melanogaster.
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3663445
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29 September 2017
Early-onset autosomal dominant Alzheimer disease: prevalence, genetic heterogeneity, and mutation spectrum
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29 September 2017
Genetic analysis of the bone morphogenetic protein-related gene, gbb, identifies multiple requirements during Drosophila development
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29 September 2017
Mammalian small stress proteins protect against oxidative stress through their ability to increase glucose-6-phosphate dehydrogenase activity and by maintaining optimal cellular detoxifying machinery
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3663445
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29 September 2017
Neuropathy target esterase and a homologous Drosophila neurodegeneration-associated mutant protein contain a novel domain conserved from bacteria to man
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3663445
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29 September 2017
Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3663445
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29 September 2017
Spongecake and eggroll: two hereditary diseases in Drosophila resemble patterns of human brain degeneration
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29 September 2017
The swiss cheese mutant causes glial hyperwrapping and brain degeneration in Drosophila.
1 reference
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3663445
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29 September 2017
Mutation in the alpha-synuclein gene identified in families with Parkinson's disease
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29 September 2017
Expression of Drosophila mushroom body mutations in alternative genetic backgrounds: a case study of the mushroom body miniature gene (mbm)
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29 September 2017
Motor neurons in Cu/Zn superoxide dismutase-deficient mice develop normally but exhibit enhanced cell death after axonal injury
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3663445
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29 September 2017
Oxidative stress, caloric restriction, and aging
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3663445
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29 September 2017
Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3663445
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29 September 2017
A VAMP-binding protein from Aplysia required for neurotransmitter release
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29 September 2017
Chronic Parkinsonism in humans due to a product of meperidine-analog synthesis
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29 September 2017
Genetic dissection of the Drosophila nervous system by means of mosaics
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3663445
retrieved
29 September 2017
Lethality patterns and morphology of selected lethal and semi-lethal mutations in the zeste-white region of Drosophila melanogaster
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3663445
retrieved
29 September 2017
The anatomy and function of a segment of the X chromosome of Drosophila melanogaster
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3663445
retrieved
29 September 2017
A Drosophila mutant with a temperature-sensitive block in nerve conduction
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3663445
retrieved
29 September 2017
Neurophysiological defects in temperature-sensitive paralytic mutants of Drosophila melanogaster
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3663445
retrieved
29 September 2017
Antioxidants can inhibit basal autophagy and enhance neurodegeneration in models of polyglutamine disease.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3663445
retrieved
27 June 2018
Motor deficit in a Drosophila model of mucolipidosis type IV due to defective clearance of apoptotic cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3663445
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27 June 2018
Indirect Suppression Involving Behavioral Mutants with Altered Nerve Excitability in DROSOPHILA MELANOGASTER.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3663445
retrieved
27 June 2018
Metabolic disruption in Drosophila bang-sensitive seizure mutants
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3663445
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27 June 2018
Ataxin-3 suppresses polyglutamine neurodegeneration in Drosophila by a ubiquitin-associated mechanism.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3663445
retrieved
27 June 2018
Genetic suppression of polyglutamine toxicity in Drosophila
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3663445
retrieved
27 June 2018
Extension of Drosophila lifespan by overexpression of human SOD1 in motorneurons
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3663445
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27 June 2018
Mammalian homolog of Drosophila retinal degeneration B rescues the mutant fly phenotype.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3663445
retrieved
27 June 2018
The tko locus, site of a behavioral mutation in D. melanogaster, codes for a protein homologous to prokaryotic ribosomal protein S12.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3663445
retrieved
27 June 2018
The structural brain mutant Vacuolar medulla of Drosophila melanogaster with specific behavioral defects and cell degeneration in the adult.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3663445
retrieved
27 June 2018
Vitamin K2 is a mitochondrial electron carrier that rescues pink1 deficiency
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3663445
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4 September 2018
Paraquat- and rotenone-induced models of Parkinson's disease.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3663445
retrieved
4 September 2018
Association between environmental exposure to pesticides and neurodegenerative diseases.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3663445
retrieved
4 September 2018
Autophagy-dependent rhodopsin degradation prevents retinal degeneration in Drosophila.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3663445
retrieved
4 September 2018
Increased energy metabolism rescues glia-induced pathology in a Drosophila model of Huntington's disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3663445
retrieved
4 September 2018
Extended lifespan of Drosophila parkin mutants through sequestration of redox-active metals and enhancement of anti-oxidative pathways
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3663445
retrieved
4 September 2018
Effects of pharmacological agents on the lifespan phenotype of Drosophila DJ-1beta mutants
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3663445
retrieved
4 September 2018
Genetic evidence linking age-dependent attenuation of the 26S proteasome with the aging process
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3663445
retrieved
4 September 2018
The effect of neuronal expression of heat shock proteins 26 and 27 on lifespan, neurodegeneration, and apoptosis in Drosophila.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3663445
retrieved
4 September 2018
Vesicle associated membrane protein B (VAPB) is decreased in ALS spinal cord.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3663445
retrieved
4 September 2018
Antioxidants cannot suppress the lethal phenotype of a Drosophila melanogaster model of Huntington's disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3663445
retrieved
4 September 2018
Distinct mitochondrial retrograde signals control the G1-S cell cycle checkpoint
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3663445
retrieved
4 September 2018
Superoxide dismutase overexpression protects dopaminergic neurons in a Drosophila model of Parkinson's disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3663445
retrieved
4 September 2018
Induction of the phase II detoxification pathway suppresses neuron loss in Drosophila models of Parkinson's disease.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3663445
retrieved
4 September 2018
Promoting basal levels of autophagy in the nervous system enhances longevity and oxidant resistance in adult Drosophila
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3663445
retrieved
4 September 2018
Methionine sulfoxide reductase A and a dietary supplement S-methyl-L-cysteine prevent Parkinson's-like symptoms.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3663445
retrieved
4 September 2018
Disruption of dopamine homeostasis underlies selective neurodegeneration mediated by alpha-synuclein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3663445
retrieved
4 September 2018
ESCRTs and Fab1 regulate distinct steps of autophagy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3663445
retrieved
4 September 2018
Drosophila DJ-1 mutants are sensitive to oxidative stress and show reduced lifespan and motor deficits
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3663445
retrieved
4 September 2018
Early-onset Alzheimer disease in families with late-onset Alzheimer disease: a potential important subtype of familial Alzheimer disease.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3663445
retrieved
4 September 2018
The coiled-coil protein shrub controls neuronal morphogenesis in Drosophila
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3663445
retrieved
4 September 2018
A new autosomal recessive spastic ataxia associated with frequent white matter changes maps to 2q33-34.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3663445
retrieved
4 September 2018
Loss of glial lazarillo, a homolog of apolipoprotein D, reduces lifespan and stress resistance in Drosophila
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3663445
retrieved
4 September 2018
Overexpression of a Drosophila homolog of apolipoprotein D leads to increased stress resistance and extended lifespan
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3663445
retrieved
4 September 2018
Rapamycin alleviates toxicity of different aggregate-prone proteins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3663445
retrieved
4 September 2018
Drosophila DJ-1 mutants show oxidative stress-sensitive locomotive dysfunction.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3663445
retrieved
4 September 2018
Drosophila DJ-1 mutants are selectively sensitive to environmental toxins associated with Parkinson's disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3663445
retrieved
4 September 2018
Mutations in Drosophila sec15 reveal a function in neuronal targeting for a subset of exocyst components
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3663445
retrieved
4 September 2018
Chronic exposure to rotenone models sporadic Parkinson's disease in Drosophila melanogaster.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3663445
retrieved
4 September 2018
A model for studying Alzheimer's Abeta42-induced toxicity in Drosophila melanogaster
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3663445
retrieved
4 September 2018
GSK-3beta inhibition reverses axonal transport defects and behavioural phenotypes in Drosophila
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3663445
retrieved
4 September 2018
Human neurodegenerative disease modeling using Drosophila.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3663445
retrieved
4 September 2018
Neural dysfunction and neurodegeneration in Drosophila Na+/K+ ATPase alpha subunit mutants.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3663445
retrieved
4 September 2018
Genetic modulation of polyglutamine toxicity by protein conjugation pathways in Drosophila
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3663445
retrieved
4 September 2018
Androgen-dependent neurodegeneration by polyglutamine-expanded human androgen receptor in Drosophila.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3663445
retrieved
4 September 2018
Tauopathy in Drosophila: neurodegeneration without neurofibrillary tangles
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3663445
retrieved
4 September 2018
Identification of genes that modify ataxin-1-induced neurodegeneration.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3663445
retrieved
4 September 2018
Expression of human FALS SOD in motorneurons of Drosophila.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3663445
retrieved
4 September 2018
Preventing neurodegeneration in the Drosophila mutant bubblegum
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3663445
retrieved
4 September 2018
Polyglutamine-expanded human huntingtin transgenes induce degeneration of Drosophila photoreceptor neurons.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3663445
retrieved
4 September 2018
Expanded polyglutamine protein forms nuclear inclusions and causes neural degeneration in Drosophila
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3663445
retrieved
4 September 2018
Defective glia in the Drosophila brain degeneration mutant drop-dead
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3663445
retrieved
4 September 2018
Rapid-onset dystonia-parkinsonism
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3663445
retrieved
20 October 2018
Mapping of Behaviour in Drosophila Mosaics
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22974305
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Abnormal Electroretinograms in Visual Mutants of Drosophila
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22974305
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Nonphototactic Mutants in a Study of Vision of Drosophila
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22974305
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Ultrastructural evidence for altered calcium in motor nerve terminals in amyotropic lateral sclerosis
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22974305
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1146/ANNUREV-GENET-110711-155456
1 reference
stated in
Europe PubMed Central
PMC publication ID
3663445
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22974305%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 February 2020
PMC publication ID
3663445
1 reference
stated in
Europe PubMed Central
PMC publication ID
3663445
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22974305%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 February 2020
PubMed publication ID
22974305
1 reference
stated in
Europe PubMed Central
PMC publication ID
3663445
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22974305%20AND%20SRC:MED&resulttype=core&format=json
retrieved
13 February 2020
ResearchGate publication ID
231182188
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