(Q37401330)

20 August 2017

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title

Customizing the targeting of IGF-1 receptor (English)

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20 August 2017

Renato Baserga

1

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20 August 2017

language of work or name

English

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publication date

1 February 2009

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20 August 2017

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20 August 2017

volume

5

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20 August 2017

issue

1

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20 August 2017

page(s)

43-50

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A functional insulin-like growth factor I receptor is required for the mitogenic and transforming activities of the epidermal growth factor receptor

20 August 2017

cites work

1 reference

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Insulin receptor substrate-1 involvement in epidermal growth factor receptor and insulin-like growth factor receptor signalling: implication for Gefitinib ('Iressa') response and resistance.

21 January 2018

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A recombinant humanized anti-insulin-like growth factor receptor type I antibody (h7C10) enhances the antitumor activity of vinorelbine and anti-epidermal growth factor receptor therapy against human cancer xenografts

21 January 2018

1 reference

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Insulin receptor substrates mediate distinct biological responses to insulin-like growth factor receptor activation in breast cancer cells.

21 January 2018

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Feedback mechanisms promote cooperativity for small molecule inhibitors of epidermal and insulin-like growth factor receptors

21 January 2018

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The insulin-like growth factor-I receptor as a target for cancer therapy

21 January 2018

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IGF1R signalling and its inhibition

21 January 2018

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Role of insulin-like growth factor 1 receptor signalling in cancer

21 January 2018

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The contradictions of the insulin-like growth factor 1 receptor

21 January 2018

1 reference

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Insulin receptor substrate-1, p70S6K, and cell size in transformation and differentiation of hemopoietic cells

21 January 2018

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Cooperative transformation of 32D cells by the combined expression of IRS-1 and V-Ha-Ras.

21 January 2018

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Simian virus 40 large tumor antigen is unable to transform mouse embryonic fibroblasts lacking type 1 insulin-like growth factor receptor

21 January 2018

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The IGF‐1 receptor in cancer biology

21 January 2018

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The role of insulin receptor isoforms and hybrid insulin/IGF-I receptors in human cancer.

21 January 2018

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Cyclolignans as inhibitors of the insulin-like growth factor-1 receptor and malignant cell growth.

21 January 2018

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Nuclear translocation of insulin receptor substrate-1 by oncogenes and Igf-I. Effect on ribosomal RNA synthesis

21 January 2018

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ETV6-NTRK3 transformation requires insulin-like growth factor 1 receptor signaling and is associated with constitutive IRS-1 tyrosine phosphorylation

21 January 2018

1 reference

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A highly conserved NTRK3 C-terminal sequence in the ETV6-NTRK3 oncoprotein binds the phosphotyrosine binding domain of insulin receptor substrate-1: an essential interaction for transformation

21 January 2018

1 reference

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Functional significance of type 1 insulin-like growth factor-mediated nuclear translocation of the insulin receptor substrate-1 and beta-catenin.

21 January 2018

1 reference

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Mammary tumorigenesis and metastasis caused by overexpression of insulin receptor substrate 1 (IRS-1) or IRS-2

21 January 2018

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The role of insulin receptor substrate-1 in transformation by v-src

21 January 2018

1 reference

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RNAi-mediated silencing of insulin receptor substrate 1 (IRS-1) enhances tamoxifen-induced cell death in MCF-7 breast cancer cells

21 January 2018

1 reference

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Differential signaling by insulin receptor substrate 1 (IRS-1) and IRS-2 in IRS-1-deficient cells

21 January 2018

1 reference

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Micro RNA 145 targets the insulin receptor substrate-1 and inhibits the growth of colon cancer cells

21 January 2018

1 reference

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Role of insulin-like growth factor-1R system in colorectal carcinogenesis

21 January 2018

1 reference

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Insulin receptor substrate-1 deficiency promotes apoptosis in the putative intestinal crypt stem cell region, limits Apcmin/+ tumors, and regulates Sox9

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.5.1.43

Acromegaly and colorectal cancer: a comprehensive review of epidemiology, biological mechanisms, and clinical implications

21 January 2018

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Effect of thalidomide on colorectal cancer liver metastases in CBA mice.

21 January 2018

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Normal growth and development in the absence of hepatic insulin-like growth factor I

21 January 2018

1 reference

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Targeting insulin-like growth factor 1 receptor in sarcomas

21 January 2018

1 reference

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Combination therapy enhances the inhibition of tumor growth with the fully human anti-type 1 insulin-like growth factor receptor monoclonal antibody CP-751,871.

21 January 2018

1 reference

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Downregulation of the type 1 insulin-like growth factor receptor in mouse melanoma cells is associated with enhanced radiosensitivity and impaired activation of Atm kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.5.1.43

Multiple signaling pathways of the insulin-like growth factor 1 receptor in protection from apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.5.1.43

Antisense RNA to the type I insulin-like growth factor receptor suppresses tumor growth and prevents invasion by rat prostate cancer cells in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.5.1.43

Inhibition of carcinoma cell growth and metastasis by a vesicular stomatitis virus G-pseudotyped retrovector expressing type I insulin-like growth factor receptor antisense

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.5.1.43

A dominant negative type I insulin-like growth factor receptor inhibits metastasis of human cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.5.1.43

Expression of insulin-like growth factor receptor (IGF-1R), c-Fos, and c-Jun in uveal melanoma: an immunohistochemical study.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.5.1.43

21 January 2018

Identifiers

DOI

10.2217/14796694.5.1.43

1 reference

20 August 2017

1 reference