(Q37412435)

20 August 2017

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title

Regulated sodium transport in the renal connecting tubule (CNT) via the epithelial sodium channel (ENaC). (English)

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20 August 2017

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Johannes Loffing

1

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20 August 2017

Christoph Korbmacher

series ordinal

2

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20 August 2017

publication date

11 March 2009

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20 August 2017

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20 August 2017

volume

458

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20 August 2017

issue

1

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20 August 2017

page(s)

111-135

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Epithelial Na+ channel mutants causing Liddle's syndrome retain ability to respond to aldosterone and vasopressin

20 August 2017

cites work

1 reference

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Insulin-stimulated trafficking of ENaC in renal cells requires PI 3-kinase activity

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Na self inhibition of human epithelial Na channel: temperature dependence and effect of extracellular proteases

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Intracellular Cs+ activates the PKA pathway, revealing a fast, reversible, Ca2+-dependent inactivation of L-type Ca2+ current

21 January 2018

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21 January 2018

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The serine/threonine kinases SGK2 and SGK3 are potent stimulators of the epithelial Na+ channel alpha,beta,gamma-ENaC

21 January 2018

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Epithelial Na channels and short-term renal response to salt deprivation

21 January 2018

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Renal function of gene-targeted mice lacking both SGK1 and SGK3.

21 January 2018

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Blunted hypertensive effect of combined fructose and high-salt diet in gene-targeted mice lacking functional serum- and glucocorticoid-inducible kinase SGK1.

21 January 2018

1 reference

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The role of Pre-H2 domains of alpha- and delta-epithelial Na+ channels in ion permeation, conductance, and amiloride sensitivity

21 January 2018

1 reference

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Epithelial sodium channel/degenerin family of ion channels: a variety of functions for a shared structure.

21 January 2018

1 reference

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cAMP-dependent activation of CFTR inhibits the epithelial sodium channel (ENaC) without affecting its surface expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-009-0656-0

Regulation of epithelial Na+ channels by aldosterone: role of Sgk1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-009-0656-0

Sodium and calcium transport pathways along the mammalian distal nephron: from rabbit to human

21 January 2018

1 reference

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Ras pathway activates epithelial Na+ channel and decreases its surface expression in Xenopus oocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-009-0656-0

Regulation of prostasin by aldosterone in the kidney.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-009-0656-0

Sodium transporter abundance profiling in kidney: effect of spironolactone

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-009-0656-0

Elements of a paracrine tubular renin-angiotensin system along the entire nephron

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-009-0656-0

Activation of the epithelial sodium channel (ENaC) by serine proteases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-009-0656-0

Collecting duct-specific gene inactivation of alphaENaC in the mouse kidney does not impair sodium and potassium balance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-009-0656-0

Antidiuretic hormone action in A6 cells: effect on apical Cl and Na conductances and synergism with aldosterone for NaCl reabsorption

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-009-0656-0

Cytoskeletal disruption in A6 kidney cells: impact on endo/exocytosis and NaCl transport regulation by antidiuretic hormone

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-009-0656-0

Impaired renal Na(+) retention in the sgk1-knockout mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-009-0656-0

The Phe-Met-Arg-Phe-amide-activated sodium channel is a tetramer

21 January 2018

1 reference

12 December 2020

Mechanisms of mineralocorticoid action

1 reference

12 December 2020

The postnatal development of the rat kidney, with special reference to the chemodifferentiation of the proximal tubule

1 reference

12 December 2020

Protease modulation of the activity of the epithelial sodium channel expressed in Xenopus oocytes

1 reference

12 December 2020

Molecular mechanisms of human hypertension

1 reference

12 December 2020

Quantitative trait loci for blood pressure exist near the IGF-1, the Liddle syndrome, the angiotensin II-receptor gene and the renin loci in man

1 reference

12 December 2020

Mineralocorticoid regulation of epithelial Na+ channels is maintained in a mouse model of Liddle's syndrome

1 reference

12 December 2020

Aldosterone regulates rapid trafficking of epithelial sodium channel subunits in renal cortical collecting duct cells via protein kinase D activation.

1 reference

12 December 2020

Distribution of immunoreactive kallikrein along the rat nephron

1 reference

12 December 2020

Sodium transport-related proteins in the mammalian distal nephron - distribution, ontogeny and functional aspects

1 reference

12 December 2020

Altered renal distal tubule structure and renal Na(+) and Ca(2+) handling in a mouse model for Gitelman's syndrome.

1 reference

12 December 2020

Rab proteins regulate epithelial sodium channel activity in colonic epithelial HT-29 cells

1 reference

12 December 2020

Developmental expression of sodium entry pathways in rat nephron.

1 reference

12 December 2020

Disinhibitory pathways for control of sodium transport: regulation of ENaC by SGK1 and GILZ.

1 reference

12 December 2020

Aldosterone responsiveness of the epithelial sodium channel (ENaC) in colon is increased in a mouse model for Liddle's syndrome.

1 reference

12 December 2020

Sites of hormone action in the mammalian nephron

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12 December 2020

Interactions of beta and gamma ENaC with Nedd4 can be facilitated by an ERK-mediated phosphorylation

1 reference

12 December 2020

Epithelial sodium channel is regulated by SNAP-23/syntaxin 1A interplay

1 reference

12 December 2020

High-conductance K channels in intercalated cells of the rat distal nephron

1 reference

12 December 2020

IGF-1 vs insulin: respective roles in modulating sodium transport via the PI-3 kinase/Sgk1 pathway in a cortical collecting duct cell line

1 reference

12 December 2020

The serum and glucocorticoid kinase sgk increases the abundance of epithelial sodium channels in the plasma membrane of Xenopus oocytes.

1 reference

12 December 2020

The connecting tubule: A functional subdivision of the rabbit distal nephron segments

1 reference

12 December 2020

Determination of epithelial Na+ channel subunit stoichiometry from single-channel conductances

1 reference

12 December 2020

SGK1 regulation of epithelial sodium transport

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12 December 2020

Ultrastructure of three-dimensionally localized distal nephron segments in superficial cortex of the rat kidney

1 reference

12 December 2020

Trafficking and cell surface stability of the epithelial Na+ channel expressed in epithelial Madin-Darby canine kidney cells

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12 December 2020

PKA-dependent ENaC trafficking requires the SNARE-binding protein complexin

1 reference

12 December 2020

Protons activate the delta-subunit of the epithelial Na+ channel in humans

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12 December 2020

Regulation of the amiloride-sensitive epithelial sodium channel by syntaxin 1A.

1 reference

12 December 2020

In vitro phosphorylation of COOH termini of the epithelial Na(+) channel and its effects on channel activity in Xenopus oocytes

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12 December 2020

SGK integrates insulin and mineralocorticoid regulation of epithelial sodium transport

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12 December 2020

CFTR expression in cortical collecting duct cells

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12 December 2020

Immunohistochemical localization of ANG II AT1 receptor in adult rat kidney using a monoclonal antibody.

1 reference

12 December 2020

Regulation of ENaC expression at the cell surface by Rab11.

1 reference

12 December 2020

Effects of growth hormone on renal tubular handling of sodium in healthy humans

1 reference

12 December 2020

Reduced expression of insulin receptors in the kidneys of insulin-resistant rats

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12 December 2020

Na+ and K+ transport by the renal connecting tubule

1 reference

12 December 2020

Differential roles of the insulin and insulin-like growth factor-I (IGF-I) receptors in response to insulin and IGF-I.

1 reference

12 December 2020

Regulation of the epithelial sodium channel by N4WBP5A, a novel Nedd4/Nedd4-2-interacting protein

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12 December 2020

Localization of epithelial sodium channel and aquaporin-2 in rabbit kidney cortex

1 reference

12 December 2020

Regulation of epithelial sodium channels by the ubiquitin-proteasome proteolytic pathway

1 reference

12 December 2020

Hyperinsulinaemia is not linked with blood pressure elevation in patients with insulinoma

1 reference

12 December 2020

Kallikrein along the rabbit microdissected nephron: a micromethod for its measurement. Effect of adrenalectomy and DOCA treatment

1 reference

12 December 2020

Acute ENaC stimulation by cAMP in a kidney cell line is mediated by exocytic insertion from a recycling channel pool

1 reference

12 December 2020

Effects of angiotensin II on electrolyte transport in the early and late distal tubule in rat kidney

1 reference

12 December 2020

Salt-sensitive hypertension and cardiac hypertrophy in mice deficient in the ubiquitin ligase Nedd4-2

1 reference

12 December 2020

A segment of gamma ENaC mediates elastase activation of Na+ transport

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12 December 2020

Cellular and subcellular distribution of the type-2 vasopressin receptor in the kidney.

1 reference

12 December 2020

Indirect activation of the epithelial Na+ channel by trypsin

1 reference

12 December 2020

Maintained ENaC trafficking in aldosterone-infused rats during mineralocorticoid and glucocorticoid receptor blockade

1 reference

12 December 2020

Regulation of the epithelial sodium channel (ENaC) by accessory proteins

1 reference

12 December 2020

Regulation of blood pressure, the epithelial sodium channel (ENaC), and other key renal sodium transporters by chronic insulin infusion in rats

1 reference

12 December 2020

cAMP stimulates CFTR-like Cl- channels and inhibits amiloride-sensitive Na+ channels in mouse CCD cells

1 reference

12 December 2020

Magnesium transport in the renal distal convoluted tubule

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12 December 2020

Epithelial sodium channels regulate cystic fibrosis transmembrane conductance regulator chloride channels in Xenopus oocytes.

1 reference

12 December 2020

The epithelial sodium channel (ENaC) is intracellularly located as a tetramer

1 reference

12 December 2020

Targeted disruption of the protein kinase SGK3/CISK impairs postnatal hair follicle development

1 reference

12 December 2020

Real-time three-dimensional imaging of lipid signal transduction: apical membrane insertion of epithelial Na(+) channels

1 reference

12 December 2020

The cystic fibrosis transmembrane conductance regulator (CFTR) inhibits ENaC through an increase in the intracellular Cl- concentration

1 reference

12 December 2020

Plasmin in nephrotic urine activates the epithelial sodium channel

1 reference

12 December 2020

Impairment of sodium balance in mice deficient in renal principal cell mineralocorticoid receptor.

1 reference

12 December 2020

Airway surface dehydration in cystic fibrosis: pathogenesis and therapy

1 reference

12 December 2020

cAMP increases density of ENaC subunits in the apical membrane of MDCK cells in direct proportion to amiloride-sensitive Na(+) transport

1 reference

12 December 2020

Liddle's syndrome mutations increase Na+ transport through dual effects on epithelial Na+ channel surface expression and proteolytic cleavage

1 reference

12 December 2020

Identification of hypertension-related genes through an integrated genomic-transcriptomic approach

1 reference

12 December 2020

Increased airway epithelial Na+ absorption produces cystic fibrosis-like lung disease in mice

1 reference

12 December 2020

Control of epithelial Na+ conductance by the cystic fibrosis transmembrane conductance regulator

1 reference

12 December 2020

Structure of acid-sensing ion channel 1 at 1.9 A resolution and low pH

1 reference

12 December 2020

Regulation of potassium (K) handling in the renal collecting duct

1 reference

12 December 2020

Intrinsic regulation of apical sodium entry in epithelia

1 reference

12 December 2020

Differential activities of glucocorticoid-induced leucine zipper protein isoforms

1 reference

12 December 2020

Human cortical distal nephron: distribution of electrolyte and water transport pathways

1 reference

12 December 2020

Mechanisms of ENaC regulation and clinical implications

1 reference

12 December 2020

Mechanism underlying flow stimulation of sodium absorption in the mammalian collecting duct.

1 reference

12 December 2020

Aldosterone-induced serum and glucocorticoid-induced kinase 1 expression is accompanied by Nedd4-2 phosphorylation and increased Na+ transport in cortical collecting duct cells

1 reference

12 December 2020

Hormonal regulation of the epithelial sodium channel ENaC: N or P(o)?

1 reference

12 December 2020

Epithelial sodium channels are activated by furin-dependent proteolysis

1 reference

12 December 2020

Regulation of the epithelial Na+ channel (ENaC) by phosphatidylinositides

1 reference

12 December 2020

14-3-3 Mediates phosphorylation-dependent inhibition of the interaction between the ubiquitin E3 ligase Nedd4-2 and epithelial Na+ channels.

1 reference

12 December 2020

Insulin-like growth factor I administration induces fluid and sodium retention in healthy adults: possible involvement of renin and atrial natriuretic factor

1 reference

12 December 2020

Prostasin is a novel human serine proteinase from seminal fluid. Purification, tissue distribution, and localization in prostate gland

1 reference

12 December 2020

Cyclosporine stimulates the renal epithelial sodium channel by elevating cholesterol

1 reference

12 December 2020

Proteolytic processing of the epithelial sodium channel gamma subunit has a dominant role in channel activation

1 reference

12 December 2020

A novel role for glucocorticoid-induced leucine zipper protein in epithelial sodium channel-mediated sodium transport

1 reference

12 December 2020

Amiloride-sensitive epithelial Na+ channel is made of three homologous subunits

1 reference

12 December 2020

Differential subcellular localization of ENaC subunits in mouse kidney in response to high- and low-Na diets

1 reference

12 December 2020

Rosiglitazone regulates ENaC and Na-K-2Cl cotransporter (NKCC2) abundance in the obese Zucker rat

1 reference

12 December 2020

Stimulation of the epithelial sodium channel (ENaC) by the serum- and glucocorticoid-inducible kinase (Sgk) involves the PY motifs of the channel but is independent of sodium feedback inhibition

1 reference

12 December 2020

Transcriptional regulation of sodium transport by vasopressin in renal cells

1 reference

12 December 2020

Regulation of the epithelial Na+ channel by peptidases

1 reference

12 December 2020

cAMP and serum and glucocorticoid-inducible kinase (SGK) regulate the epithelial Na(+) channel through convergent phosphorylation of Nedd4-2.

1 reference

12 December 2020

Glomerular ultrafiltration of IGF-I may contribute to increased renal sodium retention in diabetic nephropathy

1 reference

12 December 2020

Role of proteolysis in the activation of epithelial sodium channels

1 reference

12 December 2020

Control of sodium and potassium transport in the cortical collecting duct of the rat. Effects of bradykinin, vasopressin, and deoxycorticosterone

1 reference

12 December 2020

Distribution and regulation of expression of serum- and glucocorticoid-induced kinase-1 in the rat kidney

1 reference

12 December 2020

The growth hormone insulin-like growth factor axis in kidney revisited

1 reference

12 December 2020

Non-coordinate regulation of endogenous epithelial sodium channel (ENaC) subunit expression at the apical membrane of A6 cells in response to various transporting conditions

1 reference

12 December 2020

The deubiquitinating enzyme UCH-L3 regulates the apical membrane recycling of the epithelial sodium channel

1 reference

12 December 2020

Localisation of immunoreactive kininogen and tissue kallikrein in the human nephron

1 reference

12 December 2020

Number of subunits comprising the epithelial sodium channel

1 reference

12 December 2020

Early effect of aldosterone on the rate of synthesis of the epithelial sodium channel alpha subunit in A6 renal cells

1 reference

12 December 2020

Involvement of neutrophil elastase in crescentic glomerulonephritis

1 reference

12 December 2020

Regulation of sgk by aldosterone and its effects on the epithelial Na(+) channel.

1 reference

12 December 2020

The renal epithelial sodium channel: genetic heterogeneity and implications for the treatment of high blood pressure

1 reference

12 December 2020

Axial heterogeneity of the 'distal tubule'

1 reference

12 December 2020

Expression, transcription, and possible antagonistic interaction of the human Nedd4L gene variant: implications for essential hypertension

1 reference

12 December 2020

Trypsin can activate the epithelial sodium channel (ENaC) in microdissected mouse distal nephron.

1 reference

12 December 2020

Sgk, a putative serine/threonine kinase, is differentially expressed in the kidney of diabetic mice and humans

1 reference

12 December 2020

Serine protease activation of near-silent epithelial Na+ channels

1 reference

12 December 2020

sgk is an aldosterone-induced kinase in the renal collecting duct. Effects on epithelial na+ channels

1 reference

12 December 2020

Activation of the epithelial Na+ channel (ENaC) requires CFTR Cl- channel function

1 reference

12 December 2020

A novel pathway of epithelial sodium channel activation involves a serum- and glucocorticoid-inducible kinase consensus motif in the C terminus of the channel's alpha-subunit

1 reference

12 December 2020

Ultrastructural characterization of the connecting tubule and the different segments of the collecting duct system in the rabbit kidney

1 reference

12 December 2020

Cystic fibrosis transmembrane conductance regulator-dependent up-regulation of Kir1.1 (ROMK) renal K+ channels by the epithelial sodium channel

1 reference

12 December 2020

Participation of the chaperone Hsc70 in the trafficking and functional expression of ASIC2 in glioma cells

1 reference

12 December 2020

(NDRG2) stimulates amiloride-sensitive Na+ currents in Xenopus laevis oocytes and fisher rat thyroid cells.

1 reference

12 December 2020

Mammalian distal tubule: physiology, pathophysiology, and molecular anatomy

1 reference

12 December 2020

Distal tubular segments of the rabbit kidney after adaptation to altered Na- and K-intake. II. Changes in Na-K-ATPase activity

1 reference

12 December 2020

Pathogenesis and prevalence of hypertension in acromegaly

1 reference

12 December 2020

WNK1 activates SGK1 by a phosphatidylinositol 3-kinase-dependent and non-catalytic mechanism

1 reference

12 December 2020

Amiloride-sensitive trypsinization of apical sodium channels. Analysis of hormonal regulation of sodium transport in toad bladder

1 reference

12 December 2020

Vasopressin-V2 receptor stimulation reduces sodium excretion in healthy humans

1 reference

12 December 2020

Early aldosterone-induced gene product regulates the epithelial sodium channel by deubiquitylation.

1 reference

12 December 2020

Renal expression of exchange protein directly activated by cAMP (Epac) 1 and 2

1 reference

12 December 2020

Endogenously expressed epithelial sodium channel is present in lipid rafts in A6 cells

1 reference

12 December 2020

Direct activation of the epithelial Na(+) channel by phosphatidylinositol 3,4,5-trisphosphate and phosphatidylinositol 3,4-bisphosphate produced by phosphoinositide 3-OH kinase

1 reference

12 December 2020

Stimulation of the epithelial sodium channel (ENaC) by cAMP involves putative ERK phosphorylation sites in the C termini of the channel's beta- and gamma-subunit

1 reference

12 December 2020

Syntaxin 1A regulates ENaC via domain-specific interactions.

1 reference

12 December 2020

Increased renal responsiveness to vasopressin and enhanced V2 receptor signaling in RGS2-/- mice

1 reference

12 December 2020

Phosphorylation of Nedd4-2 by Sgk1 regulates epithelial Na(+) channel cell surface expression

1 reference

12 December 2020

Sodium transport by rat cortical collecting tubule. Effects of vasopressin and desoxycorticosterone

1 reference

12 December 2020

Sgk1 gene expression in kidney and its regulation by aldosterone: spatio-temporal heterogeneity and quantitative analysis

1 reference

12 December 2020

Na-K-ATPase activity along the rabbit, rat, and mouse nephron

1 reference

12 December 2020

Kallikrein (kininogenase) in the mouse nephron: effect of dietary potassium

1 reference

12 December 2020

Urokinase (u-PA) is produced by collecting duct principal cells and is post-transcriptionally regulated by SV40 large-T, arginine vasopressin, and epidermal growth factor

1 reference

12 December 2020

Activation of serum- and glucocorticoid-induced protein kinase (Sgk) by cyclic AMP and insulin

1 reference

12 December 2020

Development of human kidney as shown by microdissection. IV. Development of tubular portions of nephrons

1 reference

12 December 2020

11Beta-hydroxysteroid dehydrogenase, mineralocorticoid receptor, and thiazide-sensitive Na-Cl cotransporter expression by distal tubules.

1 reference

12 December 2020

Membrane cholesterol extraction decreases Na+ transport in A6 renal epithelia.

1 reference

12 December 2020

Mice lacking P2Y2 receptors have salt-resistant hypertension and facilitated renal Na+ and water reabsorption.

1 reference

12 December 2020

AMP-activated kinase inhibits the epithelial Na+ channel through functional regulation of the ubiquitin ligase Nedd4-2.

1 reference

12 December 2020

A novel neutrophil elastase inhibitor prevents elastase activation and surface cleavage of the epithelial sodium channel expressed in Xenopus laevis oocytes.

1 reference

12 December 2020

Cystic fibrosis transmembrane conductance regulator in the kidney: clues to its role?

1 reference

12 December 2020

Resetting of tubuloglomerular feedback by interrupting early distal flow

1 reference

12 December 2020

Aldosterone infusion with high-NaCl diet increases blood pressure in obese but not lean Zucker rats

1 reference

12 December 2020

Chronic candesartan alters expression and activity of NKCC2, NCC, and ENaC in the obese Zucker rat.

1 reference

12 December 2020

Molecular physiology of the WNK kinases.

1 reference

12 December 2020

Luminal P2Y2 receptor-mediated inhibition of Na+ absorption in isolated perfused mouse CCD.

1 reference

12 December 2020

Insulin and insulin-like growth factor I receptors: similarities and differences in signal transduction.

1 reference

12 December 2020

Evidence for cystic fibrosis transmembrane conductance regulator-dependent sodium reabsorption in kidney, using Cftr(tm2cam) mice

1 reference

12 December 2020

The epithelial Na+ channel is inhibited by a peptide derived from proteolytic processing of its alpha subunit.

1 reference

12 December 2020

Differential effects of Hsc70 and Hsp70 on the intracellular trafficking and functional expression of epithelial sodium channels

1 reference

12 December 2020

Molecular determinants of PI(4,5)P2 and PI(3,4,5)P3 regulation of the epithelial Na+ channel

1 reference

12 December 2020

Cleavage in the {gamma}-subunit of the epithelial sodium channel (ENaC) plays an important role in the proteolytic activation of near-silent channels

1 reference

12 December 2020

Molecular diversity and regulation of renal potassium channels

1 reference

12 December 2020

Immunocytochemical localization of the cystic fibrosis gene product CFTR

1 reference

12 December 2020

Downregulation of epithelial sodium channel (ENaC) by CFTR co-expressed in Xenopus oocytes is independent of Cl- conductance.

1 reference

12 December 2020

Increased expression but not targeting of ENaC in adrenalectomized rats with PAN-induced nephrotic syndrome

1 reference

12 December 2020

Inhibition of the epithelial Na+ channel by interaction of Nedd4 with a PY motif deleted in Liddle's syndrome.

1 reference

12 December 2020

Furin at the cutting edge: from protein traffic to embryogenesis and disease

1 reference

12 December 2020

ENaC and its regulatory proteins as drug targets for blood pressure control

1 reference

12 December 2020

Inhibition of short-circuit current in toad urinary bladder by inhibitors of glandular kallikrein

1 reference

12 December 2020

Activation of the amiloride-sensitive epithelial sodium channel by the serine protease mCAP1 expressed in a mouse cortical collecting duct cell line

1 reference

12 December 2020

Epithelial sodium channels: function, structure, and regulation

1 reference

12 December 2020

Activation of epithelial Na channels during short-term Na deprivation

1 reference

12 December 2020

ENaC-membrane interactions: regulation of channel activity by membrane order.

1 reference

12 December 2020

Mechanism of control of Na,K-ATPase in principal cells of the mammalian collecting duct

1 reference

12 December 2020

Electrophysiological and biochemical evidence that DEG/ENaC cation channels are composed of nine subunits

1 reference

12 December 2020

Minireview: regulation of epithelial Na+ channel trafficking

1 reference

12 December 2020

CFTR stabilizes ENaC at the plasma membrane

1 reference

12 December 2020

Vasopressin-inducible ubiquitin-specific protease 10 increases ENaC cell surface expression by deubiquitylating and stabilizing sorting nexin 3

1 reference

12 December 2020

Phenformin and 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside (AICAR) activation of AMP-activated protein kinase inhibits transepithelial Na+ transport across H441 lung cells.

1 reference

12 December 2020

Cell surface expression of the epithelial Na channel and a mutant causing Liddle syndrome: a quantitative approach

1 reference

12 December 2020

Synergistic activation of ENaC by three membrane-bound channel-activating serine proteases (mCAP1, mCAP2, and mCAP3) and serum- and glucocorticoid-regulated kinase (Sgk1) in Xenopus Oocytes

1 reference

12 December 2020

Molecular cloning and functional expression of a novel amiloride-sensitive Na+ channel

1 reference

12 December 2020

Regulation of the epithelial sodium channel by membrane trafficking

1 reference

12 December 2020

Mutations causing Liddle syndrome reduce sodium-dependent downregulation of the epithelial sodium channel in the Xenopus oocyte expression system.

1 reference

12 December 2020

Calcium absorption across epithelia

1 reference

12 December 2020

Regulation of the epithelial sodium channel by accessory proteins

1 reference

12 December 2020

Dietary sodium intake regulates the ubiquitin-protein ligase nedd4-2 in the renal collecting system

1 reference

12 December 2020

Tubule-tubule and tubule-arteriole contacts in rat kidney distal nephrons. A morphologic study based on computer-assisted three-dimensional reconstructions

1 reference

12 December 2020

Furin cleavage activates the epithelial Na+ channel by relieving Na+ self-inhibition.

1 reference

12 December 2020

Transcriptome of a mouse kidney cortical collecting duct cell line: effects of aldosterone and vasopressin

1 reference

12 December 2020

Structural biology: Unexpected opening

1 reference

12 December 2020

Impaired sodium excretion and increased blood pressure in mice with targeted deletion of renal epithelial insulin receptor

1 reference

12 December 2020

Developmental regulation of CFTR expression during human nephrogenesis.

1 reference

12 December 2020

Insulin increases sodium (Na+) channel density in A6 epithelia: implications for expression of hypertension.

1 reference

12 December 2020

Relationship between structure and function in distal tubule and collecting duct

1 reference

12 December 2020

Functional rafts in cell membranes

1 reference

12 December 2020

Altered urinary kallikrein excretion in human hypertension

1 reference

12 December 2020

Deubiquitylation regulates activation and proteolytic cleavage of ENaC

1 reference

12 December 2020

Epithelial sodium channel: mendelian versus essential hypertension

1 reference

12 December 2020

Subunit stoichiometry of the epithelial sodium channel.

1 reference

12 December 2020

Surface expression of epithelial Na channel protein in rat kidney

1 reference

12 December 2020

Degenerin sites mediate proton activation of deltabetagamma-epithelial sodium channel

1 reference

12 December 2020

Regulation of Na channels of the rat cortical collecting tubule by aldosterone.

1 reference

12 December 2020

Immunohistochemical localization of H-K-ATPase alpha(2c)-subunit in rabbit kidney

1 reference

12 December 2020

Dysregulation of renal salt and water transport proteins in diabetic Zucker rats

1 reference

12 December 2020

Serum- and glucocorticoid-regulated kinase 1 regulates ubiquitin ligase neural precursor cell-expressed, developmentally down-regulated protein 4-2 by inducing interaction with 14-3-3.

1 reference

12 December 2020

Urinary prostasin: a candidate marker of epithelial sodium channel activation in humans.

1 reference

12 December 2020

Insulin and IGF I receptor-mediated Na+ transport in toad urinary bladders

1 reference

12 December 2020

Localization of ROMK channels in the rat kidney.

1 reference

12 December 2020

The epithelial sodium channel: activation by membrane-bound serine proteases

1 reference

12 December 2020

Reconsideration of the development of the distal tubule of the human kidney

1 reference

12 December 2020

Distinct pools of epithelial sodium channels are expressed at the plasma membrane

1 reference

12 December 2020

Comparison of calcium and sodium transport in early and late rat distal tubules: effect of amiloride

1 reference

12 December 2020

Three-dimensional reconstruction of the mouse nephron

1 reference

12 December 2020

Insulin activates single amiloride-blockable Na channels in a distal nephron cell line (A6)

1 reference

12 December 2020

Aldosterone-mediated regulation of ENaC alpha, beta, and gamma subunit proteins in rat kidney

1 reference

12 December 2020

Non-specific activation of the epithelial sodium channel by the CFTR chloride channel

1 reference

12 December 2020

Identification and localization of BK-beta subunits in the distal nephron of the mouse kidney.

1 reference

12 December 2020

Physiologic regulation of the epithelial sodium channel by phosphatidylinositides

1 reference

12 December 2020

CFTR as a cAMP-dependent regulator of sodium channels

1 reference

12 December 2020

Resistance of mice lacking the serum- and glucocorticoid-inducible kinase SGK1 against salt-sensitive hypertension induced by a high-fat diet

1 reference

12 December 2020

Na channels in the rat connecting tubule

1 reference

12 December 2020

Aldosterone-induced Sgk1 relieves Dot1a-Af9-mediated transcriptional repression of epithelial Na+ channel alpha

1 reference

12 December 2020

Arginine vasopressin and forskolin regulate apical cell surface expression of epithelial Na+ channels in A6 cells

1 reference

12 December 2020

Plasma levels and urinary excretion of fibrinolytic and protease inhibitory proteins in nephrotic syndrome

1 reference

12 December 2020

Sodium transporters in the distal nephron and disease implications

1 reference

12 December 2020

Structural-functional relationship along the distal nephron

1 reference

12 December 2020

Early transcriptional control of ENaC (de)ubiquitylation by aldosterone

1 reference

12 December 2020

Time-dependent regulation by aldosterone of the amiloride-sensitive Na+ channel in rabbit kidney

1 reference

12 December 2020

Tyrosine kinase regulates epithelial sodium transport in A6 cells

1 reference

12 December 2020

Long-term regulation of ENaC expression in kidney by angiotensin II.

1 reference

12 December 2020

Epithelial sodium channel inhibition by AMP-activated protein kinase in oocytes and polarized renal epithelial cells.

1 reference

12 December 2020

Delta-subunit confers novel biophysical features to alpha beta gamma-human epithelial sodium channel (ENaC) via a physical interaction

1 reference

12 December 2020

A naturally occurring human Nedd4-2 variant displays impaired ENaC regulation in Xenopus laevis oocytes

1 reference

12 December 2020

Levels of urinary matrix metalloproteinase-9 (MMP-9) and renal injuries in patients with type 2 diabetic nephropathy.

1 reference

12 December 2020

Role of the UPS in Liddle syndrome

1 reference

12 December 2020

The PY motif of ENaC, mutated in Liddle syndrome, regulates channel internalization, sorting and mobilization from subapical pool

1 reference

12 December 2020

Organization of the pronephric kidney revealed by large-scale gene expression mapping.

1 reference

12 December 2020

The kinase Grk2 regulates Nedd4/Nedd4-2-dependent control of epithelial Na+ channels

1 reference

12 December 2020

Role of ubiquitylation in cellular membrane transport

1 reference

12 December 2020

Intercalated cell subtypes in connecting tubule and cortical collecting duct of rat and mouse

1 reference

12 December 2020

Plasmin activates epithelial Na+ channels by cleaving the gamma subunit.

1 reference

12 December 2020

The heterotetrameric architecture of the epithelial sodium channel (ENaC).

1 reference

12 December 2020

Distal tubular segments of the rabbit kidney after adaptation to altered Na- and K-intake. I. Structural changes

1 reference

12 December 2020

In vivo phosphorylation of the epithelial sodium channel

1 reference

12 December 2020

Regulation of Na+ channels in the cortical collecting duct by AVP and mineralocorticoids

1 reference

12 December 2020

Mineralcorticoid receptors along the nephron: [3H]aldosterone binding in rabbit tubules

1 reference

12 December 2020

17-beta Estradiol attenuates streptozotocin-induced diabetes and regulates the expression of renal sodium transporters

1 reference

12 December 2020

Regulation of ENaCs by proteases: An increasingly complex story.

1 reference

12 December 2020

Polymorphism in NEDD4L is associated with increased salt sensitivity, reduced levels of P-renin and increased levels of Nt-proANP.

1 reference

12 December 2020

Epithelial sodium channel is a key mediator of growth hormone-induced sodium retention in acromegaly.

1 reference

12 December 2020

Mineralocorticoid effects on Na-K-ATPase in individual nephron segments

1 reference

12 December 2020

Acute regulation of the epithelial Na+ channel by phosphatidylinositide 3-OH kinase signaling in native collecting duct principal cells

1 reference

12 December 2020

Sodium transport in the rabbit connecting tubule.

1 reference

12 December 2020

Mechano-sensitivity of ENaC: may the (shear) force be with you.

1 reference

12 December 2020

Ultrastructure of distal nephron cells in rat renal cortex

1 reference

12 December 2020

Role of Growth Hormone in Fluid Homeostasis

1 reference

12 December 2020

Aldosterone induces rapid apical translocation of ENaC in early portion of renal collecting system: possible role of SGK.

1 reference

12 December 2020

Hormonal regulation of ENaCs: insulin and aldosterone

1 reference

12 December 2020

14-3-3 isoforms are induced by aldosterone and participate in its regulation of epithelial sodium channels

1 reference

12 December 2020

Vasopressin V2 receptor expression along rat, mouse, and human renal epithelia with focus on TAL

1 reference

12 December 2020

Ikappab kinase-beta (ikkbeta) modulation of epithelial sodium channel activity

1 reference

12 December 2020

Sodium channels and cystic fibrosis

1 reference

12 December 2020

Lessons from mouse mutants of epithelial sodium channel and its regulatory proteins.

1 reference

12 December 2020

The epithelial sodium channel (ENaC) traffics to apical membrane in lipid rafts in mouse cortical collecting duct cells

1 reference

12 December 2020

Renal tubule sodium transporter abundance profiling in rat kidney: response to aldosterone and variations in NaCl intake

1 reference

12 December 2020

Assessment of the CFTR and ENaC association

1 reference

12 December 2020

Cell-surface expression of the channel activating protease xCAP-1 is required for activation of ENaC in the Xenopus oocyte.

1 reference

12 December 2020

Epithelial sodium channel regulated by aldosterone-induced protein sgk.

1 reference

12 December 2020

Urinary kallikrein: a physiological regulator of epithelial Na+ absorption

1 reference

12 December 2020

Apical membrane targeting of Nedd4 is mediated by an association of its C2 domain with annexin XIIIb

1 reference

12 December 2020

Characterization of the structure and regulation of two novel isoforms of serum- and glucocorticoid-induced protein kinase

1 reference

12 December 2020

Possible mediators of connecting tubule glomerular feedback

1 reference

12 December 2020

Immunohistochemical localization of colonic H-K-ATPase to the apical membrane of connecting tubule cells

1 reference

12 December 2020

Mineralocorticoid receptors: distribution and activation

1 reference

12 December 2020

Aldosterone binding in isolated tubules II. An autoradiographic study of concentration dependency in the rabbit nephron

1 reference

12 December 2020

Increased renal Na-K-ATPase, NCC, and beta-ENaC abundance in obese Zucker rats

1 reference

12 December 2020

Purinergic control of apical plasma membrane PI(4,5)P2 levels sets ENaC activity in principal cells

1 reference

12 December 2020

Inhibition of prostasin-induced ENaC activities by PN-1 and regulation of PN-1 expression by TGF-beta1 and aldosterone

1 reference

12 December 2020

24-h ambulatory blood pressure is linked to chromosome 18q21-22 and genetic variation of NEDD4L associates with cross-sectional and longitudinal blood pressure in Swedes

1 reference

12 December 2020

Molecular physiology and pathophysiology of electroneutral cation-chloride cotransporters.

1 reference

12 December 2020

Rab4 GTP/GDP modulates amiloride-sensitive sodium channel (ENaC) function in colonic epithelia

1 reference

12 December 2020

Evidence for a stimulatory effect of high potassium diet on renal kallikrein

1 reference

12 December 2020

Open probability of the epithelial sodium channel is regulated by intracellular sodium.

1 reference

12 December 2020

Effect of endogenous organic hyperinsulinaemia on blood pressure and serum triglycerides.

1 reference

12 December 2020

Extracellular Na+ removal attenuates rundown of the epithelial Na+-channel (ENaC) by reducing the rate of channel retrieval

1 reference

12 December 2020

Biochemical analysis of the membrane topology of the amiloride-sensitive Na+ channel

1 reference

12 December 2020

BK channels in the kidney.

1 reference

12 December 2020

Defective ENaC processing and function in tissue kallikrein-deficient mice.

1 reference

12 December 2020

Sodium self-inhibition of human epithelial sodium channel: selectivity and affinity of the extracellular sodium sensing site.

1 reference

12 December 2020

Collecting duct is a site of sodium retention in PAN nephrosis: a rationale for amiloride therapy

1 reference

12 December 2020

Trafficking of ENaC subunits in response to acute insulin in mouse kidney

1 reference

12 December 2020

Identification of a functional phosphatidylinositol 3,4,5-trisphosphate binding site in the epithelial Na+ channel.

1 reference

12 December 2020

ATP stimulates Cl- secretion and reduces amiloride-sensitive Na+ absorption in M-1 mouse cortical collecting duct cells.

1 reference

12 December 2020

Preferential assembly of epithelial sodium channel (ENaC) subunits in Xenopus oocytes: role of furin-mediated endogenous proteolysis

1 reference

12 December 2020

Structural Analysis of the Rabbit Kidney

1 reference

12 December 2020

Increased expression and apical targeting of renal ENaC subunits in puromycin aminonucleoside-induced nephrotic syndrome in rats

1 reference

12 December 2020

Insulin-induced phosphorylation of ENaC correlates with increased sodium channel function in A6 cells

1 reference

12 December 2020

Paracrine regulation of the epithelial Na+ channel in the mammalian collecting duct by purinergic P2Y2 receptor tone

1 reference

12 December 2020

Micropuncture study of distal tubular potassium and sodium transport in rat nephron

1 reference

12 December 2020

Sex and body-type interactions in the regulation of renal sodium transporter levels, urinary excretion, and activity in lean and obese Zucker rats.

1 reference

12 December 2020

Preventive but not late amiloride therapy reduces morbidity and mortality of lung disease in betaENaC-overexpressing mice.

1 reference

12 December 2020

Angiotensin II directly stimulates ENaC activity in the cortical collecting duct via AT(1) receptors

1 reference

12 December 2020

Purinergic inhibition of the epithelial Na+ transport via hydrolysis of PIP2.

1 reference

12 December 2020

Epithelial sodium channel: a ligand-gated channel?

1 reference

12 December 2020

Epithelial Na+ channel activation and processing in mice lacking SGK1.

1 reference

12 December 2020

New insights into epithelial sodium channel function in the kidney: site of action, regulation by ubiquitin ligases, serum- and glucocorticoid-inducible kinase and proteolysis

1 reference

12 December 2020

An epithelial serine protease activates the amiloride-sensitive sodium channel

1 reference

12 December 2020

Crosstalk between the connecting tubule and the afferent arteriole regulates renal microcirculation

1 reference

12 December 2020

Modulation of basal and peptide hormone-stimulated Na transport by membrane cholesterol content in the A6 epithelial cell line

1 reference

12 December 2020

Vasopressin-mediated regulation of epithelial sodium channel abundance in rat kidney.

1 reference

12 December 2020

Casein kinase 2 specifically binds to and phosphorylates the carboxy termini of ENaC subunits

1 reference

12 December 2020

Defective regulation of the epithelial Na+ channel by Nedd4 in Liddle's syndrome.

1 reference

12 December 2020

Sgk kinases and their role in epithelial transport

1 reference

12 December 2020

Activation of epithelial sodium channels by mouse channel activating proteases (mCAP) expressed in Xenopus oocytes requires catalytic activity of mCAP3 and mCAP2 but not mCAP1.

1 reference

12 December 2020

Epithelial Na+ channels are fully activated by furin- and prostasin-dependent release of an inhibitory peptide from the gamma-subunit.

1 reference

12 December 2020

Functional specificity of Sgk1 and Akt1 on ENaC activity

1 reference

12 December 2020

Targeted proteomic profiling of renal Na(+) transporter and channel abundances in angiotensin II type 1a receptor knockout mice

1 reference

12 December 2020

Active and inactive kallikrein in rabbit connecting tubules and urine during low and normal sodium intake

1 reference

12 December 2020

Plasminogen and antithrombin III deficiencies in the childhood nephrotic syndrome associated with plasminogenuria and antithrombinuria

1 reference

12 December 2020

The cytosolic termini of the beta- and gamma-ENaC subunits are involved in the functional interactions between cystic fibrosis transmembrane conductance regulator and epithelial sodium channel.

1 reference

12 December 2020

Angiotensin II binding sites in individual segments of the rat nephron

1 reference

12 December 2020

Defining an inhibitory domain in the alpha-subunit of the epithelial sodium channel.

1 reference

12 December 2020

Activation of epithelial sodium channels by prostasin in Xenopus oocytes

1 reference

12 December 2020

Serum and glucocorticoid-regulated kinase modulates Nedd4-2-mediated inhibition of the epithelial Na+ channel

1 reference

12 December 2020

Phosphatidylinositol 4,5-bisphosphate (PIP2) stimulates epithelial sodium channel activity in A6 cells

1 reference

12 December 2020

ATP release via anion channels

1 reference

12 December 2020

Transgenic mice and their impact on kidney research

1 reference

12 December 2020

(Patho)physiological significance of the serum- and glucocorticoid-inducible kinase isoforms

1 reference

12 December 2020

Akt mediates the effect of insulin on epithelial sodium channels by inhibiting Nedd4-2

1 reference

12 December 2020

Neutrophil elastase activates near-silent epithelial Na+ channels and increases airway epithelial Na+ transport.

1 reference

12 December 2020

14-3-3 proteins modulate the expression of epithelial Na+ channels by phosphorylation-dependent interaction with Nedd4-2 ubiquitin ligase.

1 reference

12 December 2020

Hyperaldosteronemia and activation of the epithelial sodium channel are not required for sodium retention in puromycin-induced nephrosis.

1 reference

12 December 2020

Pathogenesis of oedema in nephrotic syndrome: role of epithelial sodium channel

1 reference

12 December 2020

Deranged transcriptional regulation of cell-volume-sensitive kinase hSGK in diabetic nephropathy

1 reference

12 December 2020

Long-term effects of vasopressin on the subcellular localization of ENaC in the renal collecting system

1 reference

12 December 2020

Regulated acid-base transport in the collecting duct

1 reference

12 December 2020

A novel vasopressin-induced transcript promotes MAP kinase activation and ENaC downregulation

1 reference

12 December 2020

Regulation of NaCl transport in the renal collecting duct: lessons from cultured cells

1 reference

12 December 2020

Regulation of maturation and processing of ENaC subunits in the rat kidney

1 reference

12 December 2020

Sodium and potassium handling by the aldosterone-sensitive distal nephron: the pivotal role of the distal and connecting tubule

1 reference

12 December 2020

Immunocytochemical and immunoelectron microscopic localization of alpha-, beta-, and gamma-ENaC in rat kidney

1 reference

12 December 2020

Blood and urinary kinins in human subjects during normal and low sodium intake

1 reference

12 December 2020

Epac: a new cAMP target and new avenues in cAMP research

1 reference

12 December 2020

Immunocytochemical localization of renin and kallikrein in the rat renal cortex

1 reference

12 December 2020

WNK1 activates SGK1 to regulate the epithelial sodium channel.

1 reference

12 December 2020

Chronic exposure to vasopressin upregulates ENaC and sodium transport in the rat renal collecting duct and lung

1 reference

12 December 2020

Reduced ENaC protein abundance contributes to the lower blood pressure observed in pendrin-null mice.

1 reference

12 December 2020

Localization of the ROMK protein on apical membranes of rat kidney nephron segments.

1 reference

12 December 2020

Rab27a regulates epithelial sodium channel (ENaC) activity through synaptotagmin-like protein (SLP-5) and Munc13-4 effector mechanism

1 reference

12 December 2020

Functional identification of H-K-ATPase in intercalated cells of cortical collecting tubule.

1 reference

12 December 2020

10.1007/S00424-009-0656-0

Identifiers

DOI

1 reference

20 August 2017

1 reference