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Mitochondrial permeability transition pore induces mitochondria injury in Huntington disease.
scientific article published on 11 December 2013
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Europe PubMed Central
PMC publication ID
3878840
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24330821%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 March 2020
title
Mitochondrial permeability transition pore induces mitochondria injury in Huntington disease
(English)
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stated in
Europe PubMed Central
PMC publication ID
3878840
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24330821%20AND%20SRC:MED&resulttype=core&format=json
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3 March 2020
main subject
Huntington's disease
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mitochondrion
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based on heuristic
inferred from title
author
Rommy von Bernhardi
series ordinal
3
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Europe PubMed Central
PMC publication ID
3878840
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24330821%20AND%20SRC:MED&resulttype=core&format=json
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3 March 2020
author name string
Rodrigo A Quintanilla
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1
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Europe PubMed Central
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3878840
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24330821%20AND%20SRC:MED&resulttype=core&format=json
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3 March 2020
Youngnam N Jin
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2
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Europe PubMed Central
PMC publication ID
3878840
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24330821%20AND%20SRC:MED&resulttype=core&format=json
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3 March 2020
Gail V W Johnson
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4
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PMC publication ID
3878840
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3 March 2020
publication date
11 December 2013
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Europe PubMed Central
PMC publication ID
3878840
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retrieved
3 March 2020
published in
Molecular Neurodegeneration
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Europe PubMed Central
PMC publication ID
3878840
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24330821%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 March 2020
volume
8
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3878840
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retrieved
3 March 2020
page(s)
45
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PMC publication ID
3878840
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retrieved
3 March 2020
exact match
https://scigraph.springernature.com/pub.10.1186/1750-1326-8-45
0 references
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Impaired mitochondrial dynamics and Nrf2 signaling contribute to compromised responses to oxidative stress in striatal cells expressing full-length mutant huntingtin
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Dysregulation of mitochondrial calcium signaling and superoxide flashes cause mitochondrial genomic DNA damage in Huntington disease
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A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes.
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Could successful (mitochondrial) networking help prevent Huntington's disease?
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14 September 2017
Mutant huntingtin expression induces mitochondrial calcium handling defects in clonal striatal cells: functional consequences
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14 September 2017
Mutant huntingtin directly increases susceptibility of mitochondria to the calcium-induced permeability transition and cytochrome c release
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Striatal cells from mutant huntingtin knock-in mice are selectively vulnerable to mitochondrial complex II inhibitor-induced cell death through a non-apoptotic pathway
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14 September 2017
Transient and long-lasting openings of the mitochondrial permeability transition pore can be monitored directly in intact cells by changes in mitochondrial calcein fluorescence
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14 September 2017
Early mitochondrial calcium defects in Huntington's disease are a direct effect of polyglutamines.
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28 September 2017
Rosiglitazone treatment prevents mitochondrial dysfunction in mutant huntingtin-expressing cells: possible role of peroxisome proliferator-activated receptor-gamma (PPARgamma) in the pathogenesis of Huntington disease
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26 June 2018
Type 2 transglutaminase differentially modulates striatal cell death in the presence of wild type or mutant huntingtin
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26 June 2018
Cyclosporin A, but not FK 506, protects mitochondria and neurons against hypoglycemic damage and implicates the mitochondrial permeability transition in cell death.
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26 June 2018
Oxidative damage and metabolic dysfunction in Huntington's disease: selective vulnerability of the basal ganglia.
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26 June 2018
Mitochondrial function and parental sex effect in Huntington's disease
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26 June 2018
Paradoxical delay in the onset of disease caused by super-long CAG repeat expansions in R6/2 mice.
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2 September 2018
Mitochondrial sensitivity and altered calcium handling underlie enhanced NMDA-induced apoptosis in YAC128 model of Huntington's disease.
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2 September 2018
Three distinct mechanisms generate oxygen free radicals in neurons and contribute to cell death during anoxia and reoxygenation.
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2 September 2018
Mitochondrial-dependent Ca2+ handling in Huntington's disease striatal cells: effect of histone deacetylase inhibitors.
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2 September 2018
Transcriptional repression of PGC-1alpha by mutant huntingtin leads to mitochondrial dysfunction and neurodegeneration.
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2 September 2018
Mutant huntingtin aggregates impair mitochondrial movement and trafficking in cortical neurons
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2 September 2018
Oxidative stress is involved in the permeabilization of the inner membrane of brain mitochondria exposed to hypoxia/reoxygenation and low micromolar Ca2+.
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2 September 2018
Mitochondrial respiration and ATP production are significantly impaired in striatal cells expressing mutant huntingtin
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2 September 2018
Neurotoxic calcium transfer from endoplasmic reticulum to mitochondria is regulated by cyclin-dependent kinase 5-dependent phosphorylation of tau.
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2 September 2018
[Ca2+]i signaling between mitochondria and endoplasmic reticulum in neurons is regulated by microtubules. From mitochondrial permeability transition pore to Ca2+-induced Ca2+ release
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2 September 2018
Relationships between superoxide levels and delayed calcium deregulation in cultured cerebellar granule cells exposed continuously to glutamate
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2 September 2018
Dominant phenotypes produced by the HD mutation in STHdh(Q111) striatal cells
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2 September 2018
Ca(2+)-dependent permeability transition and complex I activity in lymphoblast mitochondria from normal individuals and patients with Huntington's or Alzheimer's disease
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2 September 2018
A YAC mouse model for Huntington's disease with full-length mutant huntingtin, cytoplasmic toxicity, and selective striatal neurodegeneration.
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2 September 2018
Mitochondrial membrane potential and hydroethidine-monitored superoxide generation in cultured cerebellar granule cells.
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2 September 2018
Mitochondrial defect in Huntington's disease caudate nucleus
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2 September 2018
Identifiers
DOI
10.1186/1750-1326-8-45
1 reference
stated in
Europe PubMed Central
PMC publication ID
3878840
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24330821%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 March 2020
Dimensions Publication ID
1009925734
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PMC publication ID
3878840
1 reference
stated in
Europe PubMed Central
PMC publication ID
3878840
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24330821%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 March 2020
PubMed publication ID
24330821
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Europe PubMed Central
PMC publication ID
3878840
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24330821%20AND%20SRC:MED&resulttype=core&format=json
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3 March 2020
ResearchGate publication ID
259315758
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