(Q37449030)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19374598%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

title

Specifically targeted gene therapy for small-cell lung cancer (English)

1 reference

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26 January 2020

0 references

2

1 reference

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26 January 2020

author name string

Camilla L Christensen

1

1 reference

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26 January 2020

Torben Gjetting

3

1 reference

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26 January 2020

Frederik Cramer

4

1 reference

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26 January 2020

Hans S Poulsen

5

1 reference

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26 January 2020

publication date

1 April 2009

1 reference

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Expert Review of Anticancer Therapy

26 January 2020

published in

1 reference

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26 January 2020

volume

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19374598%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

issue

4

1 reference

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26 January 2020

page(s)

437-452

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Chemotherapy for relapsed small cell lung cancer: a systematic review and practice guideline

26 January 2020

cites work

1 reference

Recent advances in management of small-cell lung cancer

21 January 2018

1 reference

Small cell lung cancer: have we made any progress over the last 25 years?

21 January 2018

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China approves first gene therapy

21 January 2018

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Current status of gendicine in China: recombinant human Ad-p53 agent for treatment of cancers

21 January 2018

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Cancer therapeutics: targeting the dark side of Myc.

21 January 2018

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Adenovirus-mediated gene therapy specific for small cell lung cancer cells using a Myc-Max binding motif

21 January 2018

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Enhanced expression of apoptin by the Myc-Max binding motif and SV40 enhancer for SCLC gene therapy.

21 January 2018

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Telomerase and its potential for therapeutic intervention

21 January 2018

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Adenovirus-mediated suicide SCLC gene therapy using the increased activity of the hTERT promoter by the MMRE and SV40 enhancer.

21 January 2018

1 reference

Use of gastrin-releasing peptide promoter for specific expression of thymidine kinase gene in small-cell lung carcinoma cells

21 January 2018

1 reference

The insulinoma-associated 1: a novel promoter for targeted cancer gene therapy for small-cell lung cancer

21 January 2018

1 reference

A chimeric fusion of the hASH1 and EZH2 promoters mediates high and specific reporter and suicide gene expression and cytotoxicity in small cell lung cancer cells

21 January 2018

1 reference

Meta-analysis of breast cancer microarray studies in conjunction with conserved cis-elements suggest patterns for coordinate regulation

21 January 2018

1 reference

Suicide genes for cancer therapy

21 January 2018

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21 January 2018

Connexins and cancer.

1 reference

Role of connexin genes in growth control

21 January 2018

1 reference

Comparison of the genotoxic and apoptosis-inducing properties of ganciclovir and penciclovir in Chinese hamster ovary cells transfected with the thymidine kinase gene of herpes simplex virus-1: implications for gene therapeutic approaches

21 January 2018

1 reference

Comparative analysis of DNA breakage, chromosomal aberrations and apoptosis induced by the anti-herpes purine nucleoside analogues aciclovir, ganciclovir and penciclovir

21 January 2018

1 reference

Influence of the bystander effect on HSV-tk/GCV gene therapy. A review

21 January 2018

1 reference

Suicide gene therapy mediated by the Herpes Simplex virus thymidine kinase gene/Ganciclovir system: fifteen years of application.

21 January 2018

1 reference

Flucytosine: a review of its pharmacology, clinical indications, pharmacokinetics, toxicity and drug interactions

21 January 2018

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Metabolism of 5-fluorocytosine to 5-fluorouracil in human colorectal tumor cells transduced with the cytosine deaminase gene: significant antitumor effects when only a small percentage of tumor cells express cytosine deaminase

21 January 2018

1 reference

Transfer of the bacterial gene for cytosine deaminase to mammalian cells confers lethal sensitivity to 5-fluorocytosine: a negative selection system

21 January 2018

1 reference

Enzyme/prodrug therapy for head and neck cancer using a catalytically superior cytosine deaminase

21 January 2018

1 reference

Bifunctional chimeric SuperCD suicide gene -YCD: YUPRT fusion is highly effective in a rat hepatoma model

21 January 2018

1 reference

Combination of cytosine deaminase with uracil phosphoribosyl transferase leads to local and distant bystander effects against RM1 prostate cancer in mice.

21 January 2018

1 reference

Combined suicide gene therapy for human colon cancer cells using adenovirus-mediated transfer of escherichia coli cytosine deaminase gene and Escherichia coli uracil phosphoribosyltransferase gene with 5-fluorocytosine

21 January 2018

1 reference

Sensitivity of 5-fluorouracil-resistant cancer cells to adenovirus suicide gene therapy

21 January 2018

1 reference

Synergistic anticancer effects of ganciclovir/thymidine kinase and 5-fluorocytosine/cytosine deaminase gene therapies

21 January 2018

1 reference

A novel mechanism of synergistic cytotoxicity with 5-fluorocytosine and ganciclovir in double suicide gene therapy

21 January 2018

1 reference

In vivo human carboxylesterase cDNA gene transfer to activate the prodrug CPT-11 for local treatment of solid tumors

21 January 2018

1 reference

Cellular roles of dna topoisomerases: a molecular perspective

21 January 2018

1 reference

Neuroblastoma directed therapy by a rational prodrug design of etoposide as a substrate for tyrosine hydroxylase.

21 January 2018

1 reference

Rationally designed hydrolytically activated etoposide prodrugs, a novel strategy for the treatment of neuroblastoma

21 January 2018

1 reference

Nitroreductase: a prodrug-activating enzyme for cancer gene therapy.

21 January 2018

1 reference

Expression of the bacterial nitroreductase enzyme in mammalian cells renders them selectively sensitive to killing by the prodrug CB1954.

21 January 2018

1 reference

Virus directed enzyme prodrug therapy for ovarian and pancreatic cancer using retrovirally delivered E. coli nitroreductase and CB1954.

21 January 2018

1 reference

Gene-directed enzyme prodrug therapy: quantitative bystander cytotoxicity and DNA damage induced by CB1954 in cells expressing bacterial nitroreductase

21 January 2018

1 reference

Sensitisation of human carcinoma cells to the prodrug CB1954 by adenovirus vector-mediated expression of E. coli nitroreductase.

21 January 2018

1 reference

2-Amino metabolites are key mediators of CB 1954 and SN 23862 bystander effects in nitroreductase GDEPT.

21 January 2018

1 reference

Design, synthesis, and biological evaluation of cyclic and acyclic nitrobenzylphosphoramide mustards for E. coli nitroreductase activation.

21 January 2018

1 reference

The nitroreductase prodrug SN 28343 enhances the potency of systemically administered armed oncolytic adenovirus ONYX-411(NTR).

21 January 2018

1 reference

Regressions of established breast carcinoma xenografts by carboxypeptidase G2 suicide gene therapy and the prodrug CMDA are due to a bystander effect

21 January 2018

1 reference

Systemic gene-directed enzyme prodrug therapy of hepatocellular carcinoma using a targeted adenovirus armed with carboxypeptidase G2.

21 January 2018

1 reference

Suicide gene therapy of human colon carcinoma xenografts using an armed oncolytic adenovirus expressing carboxypeptidase G2.

21 January 2018

1 reference

Virus-directed enzyme prodrug therapy: intratumoral administration of a replication-deficient adenovirus encoding nitroreductase to patients with resectable liver cancer

21 January 2018

1 reference

A phase III clinical evaluation of herpes simplex virus type 1 thymidine kinase and ganciclovir gene therapy as an adjuvant to surgical resection and radiation in adults with previously untreated glioblastoma multiforme.

21 January 2018

1 reference

Double suicide gene therapy augments the antitumor activity of a replication-competent lytic adenovirus through enhanced cytotoxicity and radiosensitization

21 January 2018

1 reference

Five-year follow-up of trial of replication-competent adenovirus-mediated suicide gene therapy for treatment of prostate cancer

21 January 2018

1 reference

Vector-mediated cancer gene therapy: an overview

21 January 2018

1 reference

Dissecting the genetic alterations involved in lung carcinogenesis.

21 January 2018

1 reference

p53, the cellular gatekeeper for growth and division

21 January 2018

1 reference

Molecular footprints of human lung cancer progression

21 January 2018

1 reference

Structure-function-rescue: the diverse nature of common p53 cancer mutants

21 January 2018

1 reference

Genetic alterations of multiple tumor suppressors and oncogenes in the carcinogenesis and progression of lung cancer.

21 January 2018

1 reference

Cancer gene-therapy: clinical trials

21 January 2018

1 reference

Small molecules that reactivate mutant p53.

21 January 2018

1 reference

Restoration of the tumor suppressor function to mutant p53 by a low-molecular-weight compound.

21 January 2018

1 reference

PRIMA-1(MET) synergizes with cisplatin to induce tumor cell apoptosis.

21 January 2018

1 reference

Synergistic tumor suppression by coexpression of FUS1 and p53 is associated with down-regulation of murine double minute-2 and activation of the apoptotic protease-activating factor 1-dependent apoptotic pathway in human non-small cell lung cancer c

21 January 2018

1 reference

Synergistic tumor suppression by coexpression of FHIT and p53 coincides with FHIT-mediated MDM2 inactivation and p53 stabilization in human non-small cell lung cancer cells

21 January 2018

1 reference

Epigenetic inactivation of a RAS association domain family protein from the lung tumour suppressor locus 3p21.3.

21 January 2018

1 reference

The CpG island of the novel tumor suppressor gene RASSF1A is intensely methylated in primary small cell lung carcinomas

21 January 2018

1 reference

Role of the Ras-association domain family 1 tumor suppressor gene in human cancers

21 January 2018

1 reference

Inactivation of RASSF1C during in vivo tumor growth identifies it as a tumor suppressor gene

21 January 2018

1 reference

Tumor suppressor RASSF1A is a microtubule-binding protein that stabilizes microtubules and induces G2/M arrest

21 January 2018

1 reference

The FHIT gene 3p14.2 is abnormal in lung cancer.

21 January 2018

1 reference

The tumor-suppressor gene FHIT is involved in the regulation of apoptosis and in cell cycle control

21 January 2018

1 reference

Induction of apoptosis by tumor suppressor FHIT via death receptor signaling pathway in human lung cancer cells

21 January 2018

1 reference

Loss and reduction of FUS1 protein expression is a frequent phenomenon in the pathogenesis of lung cancer

21 January 2018

1 reference

Myristoylation of the fus1 protein is required for tumor suppression in human lung cancer cells

21 January 2018

1 reference

Overexpression of candidate tumor suppressor gene FUS1 isolated from the 3p21.3 homozygous deletion region leads to G1 arrest and growth inhibition of lung cancer cells

21 January 2018

1 reference

Enhancement of antitumor activity of cisplatin in human lung cancer cells by tumor suppressor FUS1.

21 January 2018

1 reference

Gene therapy clinical trials worldwide to 2007--an update.

21 January 2018

1 reference

Progress in developing cationic vectors for non-viral systemic gene therapy against cancer

21 January 2018

1 reference

Non-viral vectors in cancer gene therapy: principles and progress

21 January 2018

1 reference

Molecular engineering of viral gene delivery vehicles

21 January 2018

1 reference

Progress and problems with the use of viral vectors for gene therapy

21 January 2018

1 reference

Chitosan/siRNA nanoparticle-mediated TNF-alpha knockdown in peritoneal macrophages for anti-inflammatory treatment in a murine arthritis model

21 January 2018

1 reference

Polymeric nanoparticles for siRNA delivery and gene silencing

21 January 2018

1 reference

New multivalent cationic lipids reveal bell curve for transfection efficiency versus membrane charge density: lipid-DNA complexes for gene delivery.

21 January 2018

1 reference

Non-viral gene delivery with cationic liposome-DNA complexes

21 January 2018

1 reference

Lipofection: a highly efficient, lipid-mediated DNA-transfection procedure

21 January 2018

1 reference

Successful treatment of primary and disseminated human lung cancers by systemic delivery of tumor suppressor genes using an improved liposome vector

21 January 2018

1 reference

Nanoparticle-mediated gene delivery to the lung

21 January 2018

1 reference

Nonviral delivery for genomic therapy of cancer

21 January 2018

1 reference

Phase diagram, stability, and overcharging of lamellar cationic lipid-DNA self-assembled complexes.

21 January 2018

1 reference

Stabilized plasmid-lipid particles for systemic gene therapy

21 January 2018

1 reference

Dendritic cationic lipids with highly charged headgroups for efficient gene delivery

21 January 2018

1 reference

Entrapment of small molecules and nucleic acid-based drugs in liposomes

21 January 2018

1 reference

In vivo knockdown of gene expression in brain cancer with intravenous RNAi in adult rats

21 January 2018

1 reference

Marked enhancement in gene expression by targeting the human insulin receptor

21 January 2018

1 reference

Novel liposomal formulation for targeted gene delivery

21 January 2018

1 reference

Programmable fusogenic vesicles for intracellular delivery of antisense oligodeoxynucleotides: enhanced cellular uptake and biological effects

21 January 2018

1 reference

Drug delivery systems: entering the mainstream

21 January 2018

1 reference

Cationic lipid saturation influences intracellular delivery of encapsulated nucleic acids

21 January 2018

1 reference

Characterization of liposome-mediated gene delivery: expression, stability and pharmacokinetics of plasmid DNA.

21 January 2018

1 reference

Design of noninflammatory synthetic siRNA mediating potent gene silencing in vivo

21 January 2018

1 reference

Normalization of striatal tyrosine hydroxylase and reversal of motor impairment in experimental parkinsonism with intravenous nonviral gene therapy and a brain-specific promoter

21 January 2018

1 reference

Solid lipid nanoparticles can effectively bind DNA, streptavidin and biotinylated ligands

21 January 2018

1 reference

Preparation and purification of cationic solid lipid nanospheres--effects on particle size, physical stability and cell toxicity

21 January 2018

1 reference

Targeted gene therapy of LS174 T human colon carcinoma by anti-TAG-72 immunoliposomes

21 January 2018

1 reference

Nuclear entry of nonviral vectors

21 January 2018

1 reference

Double-edged swords as cancer therapeutics: simultaneously targeting p53 and NF-kappaB pathways.

21 January 2018

1 reference

Inhibitors of NF-kappaB signaling: 785 and counting

21 January 2018

1 reference

A regulated, NFkappaB-assisted import of plasmid DNA into mammalian cell nuclei

21 January 2018

1 reference

Blockage of NF-kappaB by IKKbeta- or RelA-siRNA rather than the NF-kappaB super-suppressor IkappaBalpha mutant potentiates adriamycin-induced cytotoxicity in lung cancer cells

21 January 2018

1 reference

A peptide nucleic acid-nuclear localization signal fusion that mediates nuclear transport of DNA.

21 January 2018

1 reference

Targeted delivery of plasmid DNA into the nucleus of cells via nuclear localization signal peptide conjugated to DNA intercalating bis- and trisacridines

21 January 2018

1 reference