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S6K in geroconversion
scientific article published on 09 September 2013
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scholarly article
1 reference
stated in
Europe PubMed Central
PMCID
3885635
retrieved
20 August 2017
title
S6K in geroconversion
(English)
1 reference
stated in
Europe PubMed Central
PMCID
3885635
retrieved
20 August 2017
main subject
geroconversion
1 reference
based on heuristic
inferred from title
author
Mikhail Blagosklonny
series ordinal
3
object named as
Mikhail V Blagosklonny
1 reference
stated in
Europe PubMed Central
retrieved
20 August 2017
PMCID
3885635
Zoya N. Demidenko
series ordinal
2
object named as
Zoya N Demidenko
1 reference
stated in
Europe PubMed Central
PMCID
3885635
retrieved
20 August 2017
author name string
Olga V Leontieva
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMCID
3885635
retrieved
20 August 2017
publication date
9 September 2013
1 reference
stated in
Europe PubMed Central
PMCID
3885635
retrieved
20 August 2017
number of pages
4
1 reference
based on heuristic
inferred from page(s)
published in
Cell Cycle
1 reference
stated in
Europe PubMed Central
PMCID
3885635
retrieved
20 August 2017
volume
12
1 reference
stated in
Europe PubMed Central
PMCID
3885635
retrieved
20 August 2017
issue
20
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stated in
Europe PubMed Central
PMCID
3885635
retrieved
20 August 2017
page(s)
3249-3252
1 reference
stated in
Europe PubMed Central
PMCID
3885635
retrieved
20 August 2017
cites work
Tumor suppressor activity of the ERK/MAPK pathway by promoting selective protein degradation
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reference URL
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23 August 2017
Potential anti-aging agents suppress the level of constitutive mTOR- and DNA damage- signaling
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3885635
retrieved
23 August 2017
Depletion of nuclear histone H2A variants is associated with chronic DNA damage signaling upon drug-evoked senescence of human somatic cells
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PubMed Central
reference URL
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23 August 2017
Hyper-mitogenic drive coexists with mitotic incompetence in senescent cells
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PubMed Central
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23 August 2017
Rapamycin extends lifespan and delays tumorigenesis in heterozygous p53+/- mice
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PubMed Central
reference URL
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23 August 2017
New nanoformulation of rapamycin Rapatar extends lifespan in homozygous p53-/- mice by delaying carcinogenesis
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23 August 2017
Hypoxia and gerosuppression: the mTOR saga continues
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PubMed Central
reference URL
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23 August 2017
Niche science: the aging stem cell.
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PubMed Central
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23 August 2017
Hypoxia suppresses conversion from proliferative arrest to cellular senescence
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PubMed Central
reference URL
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23 August 2017
Suppression of replicative senescence by rapamycin in rodent embryonic cells
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PubMed Central
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23 August 2017
Rapamycin slows aging in mice
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3885635
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23 August 2017
TOR signaling and rapamycin influence longevity by regulating SKN-1/Nrf and DAF-16/FoxO
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PubMed Central
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23 August 2017
Cell cycle arrest is not yet senescence, which is not just cell cycle arrest: terminology for TOR-driven aging
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3885635
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23 August 2017
ERK crosstalks with 4EBP1 to activate cyclin D1 translation during quinol-thioether-induced tuberous sclerosis renal cell carcinoma
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3885635
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23 August 2017
DNA damaging agents and p53 do not cause senescence in quiescent cells, while consecutive re-activation of mTOR is associated with conversion to senescence
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3885635
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23 August 2017
Regulation of Drosophila lifespan by JNK signaling
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3885635
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23 August 2017
Lifespan extension by preserving proliferative homeostasis in Drosophila
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PubMed Central
reference URL
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23 August 2017
Rapamycin, but not resveratrol or simvastatin, extends life span of genetically heterogeneous mice
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3885635
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23 August 2017
Ageing in Drosophila: the role of the insulin/Igf and TOR signalling network
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3885635
retrieved
23 August 2017
Paradoxical suppression of cellular senescence by p53
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3885635
retrieved
23 August 2017
Rapamycin and quasi-programmed aging: four years later
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3885635
retrieved
23 August 2017
Rapamycin extends maximal lifespan in cancer-prone mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3885635
retrieved
23 August 2017
Mechanisms of life span extension by rapamycin in the fruit fly Drosophila melanogaster
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3885635
retrieved
23 August 2017
Ribosomal protein S6 kinase 1 signaling regulates mammalian life span
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3885635
retrieved
23 August 2017
Rapamycin fed late in life extends lifespan in genetically heterogeneous mice
1 reference
stated in
PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3885635
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23 August 2017
Cellular senescence in cancer and aging
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PubMed Central
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23 August 2017
The role of phospholipase D and phosphatidic acid in the mechanical activation of mTOR signaling in skeletal muscle
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3885635
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23 August 2017
Extension of chronological life span in yeast by decreased TOR pathway signaling
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3885635
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23 August 2017
When cells get stressed: an integrative view of cellular senescence
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PubMed Central
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23 August 2017
Oncogenic ras and p53 cooperate to induce cellular senescence
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3885635
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23 August 2017
Putting the stress on senescence
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3885635
retrieved
23 August 2017
Regulation of cellular senescence by p53.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3885635
retrieved
23 August 2017
Premature senescence involving p53 and p16 is activated in response to constitutive MEK/MAPK mitogenic signaling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3885635
retrieved
23 August 2017
Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3885635
retrieved
23 August 2017
MEK drives cyclin D1 hyperelevation during geroconversion
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3885635
retrieved
6 September 2017
Yeast-like chronological senescence in mammalian cells: phenomenon, mechanism and pharmacological suppression
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3885635
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6 September 2017
JNK activity in somatic stem cells causes loss of tissue homeostasis in the aging Drosophila gut.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3885635
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6 September 2017
Characterization of PF-4708671, a novel and highly specific inhibitor of p70 ribosomal S6 kinase (S6K1).
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3885635
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14 September 2017
Rapamycin decelerates cellular senescence
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3885635
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14 September 2017
Growth stimulation leads to cellular senescence when the cell cycle is blocked
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3885635
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14 September 2017
Regulation of cyclin D1 expression by mTORC1 signaling requires eukaryotic initiation factor 4E-binding protein 1.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3885635
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14 September 2017
Role of phospholipase D1 in the regulation of mTOR activity by lysophosphatidic acid
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3885635
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14 September 2017
p21Waf1/Cip1/Sdi1-induced growth arrest is associated with depletion of mitosis-control proteins and leads to abnormal mitosis and endoreduplication in recovering cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3885635
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28 September 2017
Attenuation of TORC1 signaling delays replicative and oncogenic RAS-induced senescence.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3885635
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26 June 2018
Rapamycin: killing two birds with one stone
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3885635
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26 June 2018
The choice between p53-induced senescence and quiescence is determined in part by the mTOR pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3885635
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26 June 2018
Exploiting the mTOR paradox for disease prevention
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3885635
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2 September 2018
Rapamycin as longevity enhancer and cancer preventative agent in the context of p53 deficiency
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3885635
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2 September 2018
Dissecting the role of mTOR complexes in cellular senescence
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3885635
retrieved
2 September 2018
Intermittent supplementation with rapamycin as a dietary restriction mimetic.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3885635
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2 September 2018
Rapamycin increases lifespan and inhibits spontaneous tumorigenesis in inbred female mice.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3885635
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2 September 2018
Pharmacological inhibition of phosphoinositide 3 and TOR kinases improves survival of Drosophila melanogaster.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3885635
retrieved
2 September 2018
Phospholipase D confers rapamycin resistance in human breast cancer cells
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3885635
retrieved
2 September 2018
Complex mechanisms underlying impaired activation of Cdk4 and Cdk2 in replicative senescence: roles of p16, p21, and cyclin D1
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24036549
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Phospholipase D2-derived phosphatidic acid binds to and activates ribosomal p70 S6 kinase independently of mTOR
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24036549
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Rapamycin slows aging in mice
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24036549
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.4161/CC.26248
1 reference
stated in
Europe PubMed Central
PMCID
3885635
retrieved
20 August 2017
PMCID
3885635
1 reference
stated in
Europe PubMed Central
PMCID
3885635
retrieved
20 August 2017
PubMed ID
24036549
1 reference
stated in
Europe PubMed Central
PMCID
3885635
retrieved
20 August 2017
ResearchGate publication ID
256611093
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