(Q37577336)

21 August 2017

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title

Senescence and p130/Rbl2: a new beginning to the end. (English)

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21 August 2017

4

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Francesco Paolo Fiorentino

21 August 2017

object named as

Francesco P Fiorentino

series ordinal

1

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Marcella Macaluso

series ordinal

3

object named as

Marcella Macaluso

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21 August 2017

Catherine E Symonds

2

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21 August 2017

publication date

11 August 2009

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21 August 2017

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21 August 2017

volume

19

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21 August 2017

issue

9

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21 August 2017

page(s)

1044-1051

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https://scigraph.springernature.com/pub.10.1038/cr.2009.96

21 August 2017

exact match

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cites work

THE LIMITED IN VITRO LIFETIME OF HUMAN DIPLOID CELL STRAINS

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A biomarker that identifies senescent human cells in culture and in aging skin in vivo

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Cellular senescence in aging primates.

21 January 2018

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Cellular senescence as a tumor-suppressor mechanism

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Dose-dependent oncogene-induced senescence in vivo and its evasion during mammary tumorigenesis.

21 January 2018

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Cellular senescence: molecular mechanisms, in vivo significance, and redox considerations

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Cellular senescence and organismal aging

21 January 2018

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Accumulation of senescent cells in mitotic tissue of aging primates

21 January 2018

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Telomeres shorten during ageing of human fibroblasts

21 January 2018

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Switching and signaling at the telomere

21 January 2018

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Telomeres, aging and cancer: in search of a happy ending

21 January 2018

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CELL BIOLOGY: Enhanced: Telomere Capping--One Strand Fits All

21 January 2018

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Cellular senescence: when bad things happen to good cells

21 January 2018

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Dissecting the senescence-like program in tumor cells activated by Ras signaling

21 January 2018

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From G0 to S phase: a view of the roles played by the retinoblastoma (Rb) family members in the Rb-E2F pathway

21 January 2018

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Cooperation between p53 and p130(Rb2) in induction of cellular senescence

21 January 2018

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Rb-mediated heterochromatin formation and silencing of E2F target genes during cellular senescence

21 January 2018

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Regulation of cellular senescence by Rb2/p130.

21 January 2018

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Targeted disruption of the three Rb-related genes leads to loss of G(1) control and immortalization

21 January 2018

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https://api.crossref.org/works/10.1038%2FCR.2009.96

Ablation of the retinoblastoma gene family deregulates G(1) control causing immortalization and increased cell turnover under growth-restricting conditions

21 January 2018

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p107 and p130: versatile proteins with interesting pockets

21 January 2018

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E2F mediates cell cycle-dependent transcriptional repression in vivo by recruitment of an HDAC1/mSin3B corepressor complex

21 January 2018

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The retinoblastoma protein and cell cycle control

21 January 2018

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The E2F transcriptional network: old acquaintances with new faces

21 January 2018

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Critical pathways in cellular senescence and immortalization revealed by gene expression profiling.

21 January 2018

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Unexpected pieces to the senescence puzzle

21 January 2018

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Involvement of the cyclin-dependent kinase inhibitor p16 (INK4a) in replicative senescence of normal human fibroblasts

21 January 2018

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Differential roles for cyclin-dependent kinase inhibitors p21 and p16 in the mechanisms of senescence and differentiation in human fibroblasts

21 January 2018

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Visualizing the dynamics of p21(Waf1/Cip1) cyclin-dependent kinase inhibitor expression in living animals

21 January 2018

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Reversal of human cellular senescence: roles of the p53 and p16 pathways

21 January 2018

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Mitogenic signalling and the p16INK4a-Rb pathway cooperate to enforce irreversible cellular senescence

21 January 2018

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Regulation of p16CDKN2 expression and its implications for cell immortalization and senescence

21 January 2018

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Inhibition of E2F activity by the cyclin-dependent protein kinase inhibitor p21 in cells expressing or lacking a functional retinoblastoma protein

21 January 2018

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https://api.crossref.org/works/10.1038%2FCR.2009.96

Telomere shortening triggers senescence of human cells through a pathway involving ATM, p53, and p21(CIP1), but not p16(INK4a)

21 January 2018

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Regulation of growth arrest in senescence: telomere damage is not the end of the story

21 January 2018

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Regulation of cellular senescence by p53.

21 January 2018

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Human cell senescence as a DNA damage response.

21 January 2018

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A DNA damage checkpoint response in telomere-initiated senescence

21 January 2018

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21 January 2018

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CDK inhibitors: positive and negative regulators of G1-phase progression

21 January 2018

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https://api.crossref.org/works/10.1038%2FCR.2009.96

Cloning of senescent cell-derived inhibitors of DNA synthesis using an expression screen

21 January 2018

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https://api.crossref.org/works/10.1038%2FCR.2009.96

Hypersensitivity to chromium-induced DNA damage correlates with constitutive deregulation of upstream p53 kinases in p21-/- HCT116 colon cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2009.96

p21CDKN1A allows the repair of replication-mediated DNA double-strand breaks induced by topoisomerase I and is inactivated by the checkpoint kinase inhibitor 7-hydroxystaurosporine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2009.96

The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2009.96

Proliferating cell nuclear antigen and p21 are components of multiple cell cycle kinase complexes

21 January 2018

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https://api.crossref.org/works/10.1038%2FCR.2009.96

Cell-cycle restriction limits DNA damage and maintains self-renewal of leukaemia stem cells

21 January 2018

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https://api.crossref.org/works/10.1038%2FCR.2009.96

DNA methyltransferases control telomere length and telomere recombination in mammalian cells

21 January 2018

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https://api.crossref.org/works/10.1038%2FCR.2009.96

A mammalian microRNA cluster controls DNA methylation and telomere recombination via Rbl2-dependent regulation of DNA methyltransferases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2009.96

p21Waf1/Cip1 plays a critical role in modulating senescence through changes of DNA methylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2009.96

DNA methyltransferase inhibition in normal human fibroblasts induces a p21-dependent cell cycle withdrawal

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2009.96

Recombinant human DNA (cytosine-5) methyltransferase. I. Expression, purification, and comparison of de novo and maintenance methylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2009.96

DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2009.96

Co-operation and communication between the human maintenance and de novo DNA (cytosine-5) methyltransferases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2009.96

Distinct roles for p107 and p130 in Rb-independent cellular senescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2009.96

A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2009.96

G1 phase progression: cycling on cue

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2009.96

INK4a-deficient human diploid fibroblasts are resistant to RAS-induced senescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2009.96

Both Rb/p16INK4a inactivation and telomerase activity are required to immortalize human epithelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2009.96

A two-stage, p16(INK4A)- and p53-dependent keratinocyte senescence mechanism that limits replicative potential independent of telomere status

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2009.96

A novel role for high-mobility group a proteins in cellular senescence and heterochromatin formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2009.96

Loss of linker histone H1 in cellular senescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2009.96

Remodeling of chromatin structure in senescent cells and its potential impact on tumor suppression and aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2009.96

Rb targets histone H3 methylation and HP1 to promoters

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2009.96

Transcriptional repression by the retinoblastoma protein through the recruitment of a histone methyltransferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2009.96

Definition of pRB- and p53-dependent and -independent steps in HIRA/ASF1a-mediated formation of senescence-associated heterochromatin foci

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2009.96

Cellular senescence and chromatin structure

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2009.96

ROS as a tumour suppressor?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2009.96

Regulation of dihydrofolate reductase gene expression and E2F components in human diploid fibroblasts during growth and senescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2009.96

E2F-4 and E2F-5, two members of the E2F family, are expressed in the early phases of the cell cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2009.96

Altered cell cycle kinetics, gene expression, and G1 restriction point regulation in Rb-deficient fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2009.96

pRB and p107/p130 are required for the regulated expression of different sets of E2F responsive genes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2009.96

The retinoblastoma gene family: cousins with overlapping interests

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2009.96

Replicative senescence, aging and growth-regulatory transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2009.96

7 January 2021

Inducing cellular senescence using defined genetic elements

1 reference

https://api.crossref.org/works/10.1038%2FCR.2009.96

7 January 2021

p53 is preferentially recruited to the promoters of growth arrest genes p21 and GADD45 during replicative senescence of normal human fibroblasts

1 reference

https://api.crossref.org/works/10.1038%2FCR.2009.96

7 January 2021

Comparison of global DNA methylation profiles in replicative versus premature senescence

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https://api.crossref.org/works/10.1038%2FCR.2009.96

7 January 2021

Identifiers

DOI

10.1038/CR.2009.96

1 reference

21 August 2017

1 reference