(Q37579215)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19678792%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

review article

1 reference

title

Recent trends in stabilising peptides and proteins in pharmaceutical formulation - considerations in the choice of excipients (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19678792%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19678792%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

Holger Grohganz

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19678792%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

author name string

Susanne Hostrup

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19678792%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

Eva Horn Moeller

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19678792%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

language of work or name

English

0 references

publication date

1 November 2009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19678792%20AND%20SRC:MED&resulttype=core&format=json

Expert Opinion on Drug Delivery

5 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19678792%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

volume

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19678792%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

issue

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19678792%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

page(s)

1219-1230

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19678792%20AND%20SRC:MED&resulttype=core&format=json

The formulation of biopharmaceutical products

5 February 2020

cites work

1 reference

https://api.crossref.org/works/10.1517%2F17425240903199143

Instability, stabilization, and formulation of liquid protein pharmaceuticals

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903199143

Protein formulation and fill-finish operations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903199143

Current perspectives on stability of protein drug products during formulation, fill and finish operations

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903199143

Minimizing frustration by folding in an aqueous environment

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903199143

Factors affecting short-term and long-term stabilities of proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903199143

Protein hydration, thermodynamic binding, and preferential hydration

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903199143

Investigation of cosolute-protein preferential interaction coefficients: new insight into the mechanism by which arginine inhibits aggregation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903199143

Inhibition of protein aggregation in vitro and in vivo by a natural osmoprotectant

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903199143

Effect of monomeric and oligomeric sugar osmolytes on DeltaGD, the Gibbs energy of stabilization of the protein at different pH values: is the sum effect of monosaccharide individually additive in a mixture?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903199143

Thermostabilization mechanism of bovine serum albumin by trehalose

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903199143

Effect of trehalose on protein structure

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903199143

Role of arginine in protein refolding, solubilization, and purification

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903199143

Dendrimers destabilize proteins in a generation-dependent manner involving electrostatic interactions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903199143

Formulation development and manufacturing of a gastrin/CCK-2 receptor targeting peptide as an intermediate drug product for a clinical imaging study

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903199143

Effect of excipients on PLGA film degradation and the stability of an incorporated peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903199143

Comparison of the effects of Mg(OH)2 and sucrose on the stability of bovine serum albumin encapsulated in injectable poly(D,L-lactide-co-glycolide) implants

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903199143

Effects of Tween 20 and Tween 80 on the stability of Albutropin during agitation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903199143

Preparation of polysaccharide glassy microparticles with stabilization of proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903199143

Effect of polyols on polyethylene glycol (PEG)-induced precipitation of proteins: Impact on solubility, stability and conformation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903199143

Effect of the molecular weight of poly(ethylene glycol) used as emulsifier on alpha-chymotrypsin stability upon encapsulation in PLGA microspheres

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903199143

Design of freeze-drying processes for pharmaceuticals: practical advice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903199143

Lyophilization and development of solid protein pharmaceuticals

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903199143

Role of trehalose in moisture-induced aggregation of bovine serum albumin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903199143

Mannitol-sucrose mixtures--versatile formulations for protein lyophilization

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903199143

Freeze drying of human serum albumin (HSA) nanoparticles with different excipients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903199143

Effect of sorbitol and residual moisture on the stability of lyophilized antibodies: Implications for the mechanism of protein stabilization in the solid state.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903199143

Do co-spray dried excipients offer better lysozyme stabilisation than single excipients?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903199143

Polymer-based sustained-release dosage forms for protein drugs, challenges, and recent advances

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903199143

Protein drug stability: a formulation challenge

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903199143

Effect of nanoparticles on protein folding and fibrillogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903199143

Recent advances in the stabilization of proteins encapsulated in injectable PLGA delivery systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903199143

Effect of salts on lysozyme stability at the water–oil interface and upon encapsulation in poly(lactic‐co‐glycolic) acid microspheres

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903199143

Protein instability in poly(lactic-co-glycolic acid) microparticles.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903199143

Preparation of glucagon-like peptide-1 loaded PLGA microspheres: characterizations, release studies and bioactivities in vitro/in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903199143

Stabilization of recombinant human growth hormone against emulsification-induced aggregation by Pluronic surfactants during microencapsulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903199143

Maintaining bioactivity of NGF for controlled release from PLGA using PEG.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903199143

Role of a novel excipient poly(ethylene glycol)-b-poly(L-histidine) in retention of physical stability of insulin at aqueous/organic interface

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903199143

Promotion of bone regeneration by CCN2 incorporated into gelatin hydrogel.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903199143

In vitro and in vivo release of vascular endothelial growth factor from gelatin microparticles and biodegradable composite scaffolds.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903199143

Novel composite microparticles for protein stabilization and delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903199143

The physical state of mannitol after freeze-drying: effects of mannitol concentration, freezing rate, and a noncrystallizing cosolute.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903199143

Excipient crystallinity and its protein-structure-stabilizing effect during freeze-drying.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903199143

Real-time in situ monitoring of lysozyme during lyophilization using infrared spectroscopy: dehydration stress in the presence of sucrose

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903199143

Effective inhibition of mannitol crystallization in frozen solutions by sodium chloride

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903199143

Solute Crystallization in Mannitol–Glycine Systems—Implications on Protein Stabilization in Freeze‐Dried Formulations

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903199143

Polysorbates 20 and 80 used in the formulation of protein biotherapeutics: structure and degradation pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903199143

Stability of proteins: temperature, pressure and the role of the solvent

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903199143

Measuring and increasing protein solubility.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903199143

A simple method for improving protein solubility and long-term stability.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903199143

Role of cations in stability of acidic protein Desulfovibrio desulfuricans apoflavodoxin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903199143

Salts enhance both protein stability and amyloid formation of an immunoglobulin light chain

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903199143

Evaluation of Hofmeister effects on the kinetic stability of proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903199143

Toward understanding insulin fibrillation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903199143

The influence of ionic strength and pH on the aggregation properties of zinc-free insulin studied by static and dynamic laser light scattering

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903199143

Effects of pH, temperature, and sucrose on benzyl alcohol-induced aggregation of recombinant human granulocyte colony stimulating factor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903199143

Mechanism for benzyl alcohol-induced aggregation of recombinant human interleukin-1 receptor antagonist in aqueous solution

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903199143

Hepatotoxicity during rapid intravenous loading with amiodarone: Description of three cases and review of the literature

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903199143

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903199143

Immunogenicity of therapeutic proteins: clinical implications and future prospects

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903199143

Evaluation of the physical stability of the EC5 domain of E-cadherin: effects of pH, temperature, ionic strength, and disulfide bonds

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903199143

Design of new enzyme stabilizers inspired by glycosides of hyperthermophilic microorganisms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903199143

Effects of Triton X-100 nanoaggregates on dimerization and antioxidant activity of morin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903199143

Influence of histidine on the stability and physical properties of a fully human antibody in aqueous and solid forms

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903199143

Impact of critical process and formulation parameters affecting in-process stability of lactate dehydrogenase during the secondary drying stage of lyophilization: a mini freeze dryer study

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903199143

Effects of hydrophilic cyclodextrins on aggregation of recombinant human growth hormone

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903199143

Optimization of storage stability of lyophilized actin using combinations of disaccharides and dextran.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903199143

Influence of polyols on the stability and kinetic parameters of invertase from Candida utilis: correlation with the conformational stability and activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903199143

Effects of Tween 80 and sucrose on acute short-term stability and long-term storage at -20 degrees C of a recombinant hemoglobin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903199143

Solid state chemistry of proteins: II. The correlation of storage stability of freeze-dried human growth hormone (hGH) with structure and dynamics in the glassy solid

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903199143

Infrared microscopy for in situ measurement of protein secondary structure during freezing and freeze-drying

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903199143

Conformational and bioactivity analysis of insulin: freeze-drying TBA/water co-solvent system in the presence of surfactant and sugar

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903199143

Protection mechanism of Tween 80 during freeze-thawing of a model protein, LDH.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903199143

Physical characterisation of formulations for the development of two stable freeze-dried proteins during both dried and liquid storage.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903199143

A new mechanism for decreasing aggregation of recombinant human interferon-gamma by a surfactant: slowed dissolution of lyophilized formulations in a solution containing 0.03% polysorbate 20.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903199143

Dendrimer Effects on Peptide and Protein Fibrillation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425240903199143

10.1517/17425240903199143

21 January 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19678792%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

1 reference