(Q37801886)

23 August 2017

title

Follow-up actions from positive results of in vitro genetic toxicity testing (English)

1 reference

23 August 2017

1 reference

18

Jan van Benthem

0 references

author name string

Kerry L Dearfield

1

1 reference

23 August 2017

Véronique Thybaud

2

1 reference

23 August 2017

Michael C Cimino

3

1 reference

23 August 2017

Laura Custer

4

1 reference

23 August 2017

Andreas Czich

5

1 reference

23 August 2017

James S Harvey

6

1 reference

23 August 2017

Susan Hester

7

1 reference

23 August 2017

James H Kim

8

1 reference

23 August 2017

David Kirkland

9

1 reference

23 August 2017

Dan D Levy

10

1 reference

23 August 2017

Elisabeth Lorge

11

1 reference

23 August 2017

Martha M Moore

12

1 reference

23 August 2017

Gladys Ouédraogo-Arras

13

1 reference

23 August 2017

Maik Schuler

14

1 reference

23 August 2017

Willi Suter

15

1 reference

23 August 2017

Kevin Sweder

16

1 reference

23 August 2017

Kirk Tarlo

17

1 reference

23 August 2017

Jan van Benthem

18

1 reference

23 August 2017

Freddy van Goethem

19

1 reference

23 August 2017

Kristine L Witt

20

1 reference

23 August 2017

publication date

20 October 2010

1 reference

Environmental and Molecular Mutagenesis

23 August 2017

published in

1 reference

23 August 2017

volume

52

1 reference

23 August 2017

issue

3

1 reference

23 August 2017

page(s)

177-204

1 reference

IPCS harmonization of methods for the prediction and quantification of human carcinogenic/mutagenic hazard, and for indicating the probable mechanism of action of carcinogens.

23 August 2017

cites work

1 reference

Workshop on the relationship between short-term information and carcinogenicity; Williamsburg, Virginia, January 20-23, 1987.

21 January 2018

1 reference

Comparative overview of current international strategies and guidelines for genetic toxicology testing for regulatory purposes

21 January 2018

1 reference

Mutagenicity testing for chemical risk assessment: update of the WHO/IPCS Harmonized Scheme

21 January 2018

1 reference

Current and future application of genetic toxicity assays: the role and value of in vitro mammalian assays

21 January 2018

1 reference

Mouse lymphoma thymidine kinase locus gene mutation assay: International Workshop on Genotoxicity Test Procedures Workgroup Report.

21 January 2018

1 reference

Mouse lymphoma thymidine kinase gene mutation assay: follow-up International Workshop on Genotoxicity Test Procedures, New Orleans, Louisiana, April 2000.

21 January 2018

1 reference

Mouse lymphoma thymidine kinase gene mutation assay: follow-up meeting of the International Workshop on Genotoxicity Testing--Aberdeen, Scotland, 2003--Assay acceptance criteria, positive controls, and data evaluation

21 January 2018

1 reference

Single cell gel/comet assay: guidelines for in vitro and in vivo genetic toxicology testing

21 January 2018

1 reference

Report of the IWGT working group on strategy/interpretation for regulatory in vivo tests II. Identification of in vivo-only positive compounds in the bone marrow micronucleus test

21 January 2018

1 reference

Mammalian cell gene mutation assays working group report

21 January 2018

1 reference

Summary report of the Working Group on Mammalian Germ Cell Tests

21 January 2018

1 reference

Interactions of histidine-containing test substances and extraction methods with the Ames mutagenicity test

21 January 2018

1 reference

Genotoxicity of 17 gyrase- and four mammalian topoisomerase II-poisons in prokaryotic and eukaryotic test systems

21 January 2018

1 reference

Methods for detecting carcinogens and mutagens with the Salmonella/mammalian-microsome mutagenicity test

21 January 2018

1 reference

Molecular dissection of mutations at the heterozygous thymidine kinase locus in mouse lymphoma cells

21 January 2018

1 reference

Assessing the risk of heritable gene mutation in mammals: drosophila sex-linked recessive lethal test and tests measuring DNA damage and repair in mammalian germ cells

21 January 2018

1 reference

Series: current issues in mutagenesis and carcinogenesis, No. 65. The genotoxicity and carcinogenicity of paracetamol: a regulatory (re)view

21 January 2018

1 reference

IPCS framework for analyzing the relevance of a cancer mode of action for humans.

21 January 2018

1 reference

IPCS framework for analyzing the relevance of a noncancer mode of action for humans

21 January 2018

1 reference

The in vivo comet assay: use and status in genotoxicity testing

21 January 2018

1 reference

Mutation tests in Neurospora crassa. A report of the U.S. Environmental Protection Agency Gene-Tox Program

21 January 2018

1 reference

Implications of treatment-condition-induced genotoxicity for chemical screening and data interpretation

21 January 2018

1 reference

Fourth International Workgroup on Genotoxicity testing: results of the in vivo Comet assay workgroup

21 January 2018

1 reference

Mutant frequency and mutational spectra in the Tk and Hprt genes of N-ethyl-N-nitrosourea-treated mouse lymphoma cellsdagger

21 January 2018

1 reference

The comet assay for DNA damage and repair: principles, applications, and limitations

21 January 2018

1 reference

ECVAM retrospective validation of in vitro micronucleus test (MNT)

21 January 2018

1 reference

Considerations in the U.S. Environmental Protection Agency's testing approach for mutagenicity

21 January 2018

1 reference

A strategy for the risk assessment of human genotoxic metabolites.

21 January 2018

1 reference

Stage specificity, dose response, and doubling dose for mouse minisatellite germ-line mutation induced by acute radiation

21 January 2018

1 reference

Leukaemia-specific chromosome damage detected by comet with fluorescence in situ hybridization (comet-FISH).

21 January 2018

1 reference

The mutagenic effects of diacridines and diquinolines in microbial systems

21 January 2018

1 reference

Report from working group on in vitro tests for chromosomal aberrations

21 January 2018

1 reference

Critical features of bacterial mutation assays

21 January 2018

1 reference

Recommendations for the performance of bacterial mutation assays

21 January 2018

1 reference

Heritable translocation test in mice

21 January 2018

1 reference

Sulfotransferases in the bioactivation of xenobiotics

21 January 2018

1 reference

Chemical modifiers of unstable expanded simple sequence repeats: what goes up, could come down

21 January 2018

1 reference

Current status of bioassays in genetic toxicology--the dominant lethal assay. A report of the U.S. Environmental Protection Agency Gene-Tox Program

21 January 2018

1 reference

In vivo rodent erythrocyte micronucleus assay

21 January 2018

1 reference

In vivo erythrocyte micronucleus assay III. Validation and regulatory acceptance of automated scoring and the use of rat peripheral blood reticulocytes, with discussion of non-hematopoietic target cells and a single dose-level limit test.

21 January 2018

1 reference

Synthesis, metabolism and structure-mutagenicity relationships of novel 4-nitro-(imidazoles and pyrazoles) in Salmonella typhimurium.

21 January 2018

1 reference

Mutation-rate determinations based on electrophoretic analysis of laboratory mice

21 January 2018

1 reference

Follow-up testing of rodent carcinogens not positive in the standard genotoxicity testing battery: IWGT workgroup report

21 January 2018

1 reference

In vitro approaches to develop weight of evidence (WoE) and mode of action (MoA) discussions with positive in vitro genotoxicity results

21 January 2018

1 reference

Report from the in vitro micronucleus assay working group

21 January 2018

1 reference

Strategy for genotoxicity testing--metabolic considerations

21 January 2018

1 reference

Detailed review of transgenic rodent mutation assays

21 January 2018

1 reference

DNA repair assays as tests for environmental mutagens. A report of the U.S. EPA Gene-Tox Program

21 January 2018

1 reference

An evaluation of tests using DNA repair-deficient bacteria for predicting genotoxicity and carcinogenicity. A report of the U.S. EPA's Gene-TOX Program

21 January 2018

1 reference

Different cytotoxic and clastogenic effects of epigallocatechin gallate in various cell-culture media due to variable rates of its oxidation in the culture medium.

21 January 2018

1 reference

SFTG international collaborative study on in vitro micronucleus test I. General conditions and overall conclusions of the study

21 January 2018

1 reference

Recommendations for the performance of UDS tests in vitro and in vivo

21 January 2018

1 reference

Revised methods for the Salmonella mutagenicity test

21 January 2018

1 reference

Validation study of the in vitro micronucleus test in a Chinese hamster lung cell line (CHL/IU).

21 January 2018

1 reference

Recent developments in frameworks to consider human relevance of hypothesized modes of action for tumours in animals

21 January 2018

1 reference

Differential mutant quantitation at the mouse lymphoma tk and CHO hgprt loci

21 January 2018

1 reference

Mouse Lymphoma Thymidine Kinase Gene Mutation Assay: International Workshop on Genotoxicity Tests Workgroup Report—Plymouth, UK 2002

21 January 2018

1 reference

Analysis of in vivo mutation data can inform cancer risk assessment.

21 January 2018

1 reference

The Ames Salmonella/microsome mutagenicity assay

21 January 2018

1 reference

Ciprofloxacin: mammalian DNA topoisomerase type II poison in vivo.

21 January 2018

1 reference

ICH-harmonised guidances on genotoxicity testing of pharmaceuticals: evolution, reasoning and impact.

21 January 2018

1 reference

Improving dose selection and identification of aneugens in the in vitro chromosome aberration test by integration of flow cytometry-based methods.

21 January 2018

1 reference

A new sensitive 32P-postlabeling assay based on the specific enzymatic conversion of bulky DNA lesions to radiolabeled dinucleotides and nucleoside 5'-monophosphates.

21 January 2018

1 reference

Roles of glucuronidation and UDP-glucuronosyltransferases in xenobiotic bioactivation reactions

21 January 2018

1 reference

Use of the mouse spot test in chemical mutagenesis: interpretation of past data and recommendations for future work

21 January 2018

1 reference

The mouse specific-locus test with agents other than radiations: interpretation of data and recommendations for future work

21 January 2018

1 reference

The comet assay with multiple mouse organs: comparison of comet assay results and carcinogenicity with 208 chemicals selected from the IARC monographs and U.S. NTP Carcinogenicity Database

21 January 2018

1 reference

International Commission for Protection Against Environmental Mutagens and Carcinogens. Genotoxicity under extreme culture conditions. A report from ICPEMC Task Group 9.

21 January 2018

1 reference

Detection of induced male germline mutation: correlations and comparisons between traditional germline mutation assays, transgenic rodent assays and expanded simple tandem repeat instability assays.

21 January 2018

1 reference

Genotoxicity of lomefloxacin--an antibacterial drug in somatic and germ cells of Swiss albino mice in vivo

21 January 2018

1 reference

A simple technique for quantitation of low levels of DNA damage in individual cells

21 January 2018

1 reference

The bleomycin amplification assay in V79 cells predicts frameshift mutagenicity of intercalative agents

21 January 2018

1 reference

Enhancement of bleomycin-induced micronucleus formation in V79 cells as a rapid and sensitive screen for non-covalent DNA-binding compounds

21 January 2018

1 reference

IPCS conceptual framework for evaluating a mode of action for chemical carcinogenesis

21 January 2018

1 reference

Genotoxicity assessment of the antiepileptic drug AMP397, an Ames-positive aromatic nitro compound.

21 January 2018

1 reference

In vivo transgenic mutation assays

21 January 2018

1 reference

Strategy for genotoxicity testing: hazard identification and risk assessment in relation to in vitro testing.

21 January 2018

1 reference

Report from the working group on the in vivo mammalian bone marrow chromosomal aberration test.

21 January 2018

1 reference

Sister-chromatid exchange: second report of the Gene-Tox Program

21 January 2018

1 reference

In vitro micronucleus assay with Chinese hamster V79 cells - results of a collaborative study with in situ exposure to 26 chemical substances

21 January 2018

1 reference

The mouse lymphoma assay detects recombination, deletion, and aneuploidy

21 January 2018

1 reference

Advances in the application of germline tandem repeat instability for in situ monitoring

21 January 2018

1 reference

Identification of rodent carcinogens and noncarcinogens using genetic toxicity tests: premises, promises, and performance.

21 January 2018

1 reference

Testing of chemicals for genetic activity with Saccharomyces cerevisiae: a report of the U.S. Environmental Protection Agency Gene-Tox Program.

21 January 2018

1 reference

Genotoxicity risk assessment: a proposed classification strategy

21 January 2018

1 reference

7 January 2021

Cytotoxicity and chromosome aberrations in vitro: experience in industry and the case for an upper limit on toxicity in the aberration assay

1 reference

7 January 2021

In vivo transgenic mutation assays

1 reference

7 January 2021

Comments and perspective on the EPA workshop on "The relationship between short-term test information and carcinogenicity"

1 reference

7 January 2021

Report from the In Vitro Micronucleus Assay Working Group

1 reference

7 January 2021

The L5178Y/tk+/- mouse lymphoma specific gene and chromosomal mutation assay a phase III report of the U.S. Environmental Protection Agency Gene-Tox Program

1 reference

7 January 2021

Mouse lymphoma thymidine kinase gene mutation assay: meeting of the International Workshop on Genotoxicity Testing, San Francisco, 2005, recommendations for 24-h treatment

1 reference

7 January 2021

Methods of DNA adduct determination and their application to testing compounds for genotoxicity

1 reference

7 January 2021

Report of the IWGT working group on strategies and interpretation of regulatory in vivo tests I. Increases in micronucleated bone marrow cells in rodents that do not indicate genotoxic hazards

1 reference

7 January 2021

Evaluation of thresholds for benomyl- and carbendazim-induced aneuploidy in cultured human lymphocytes using fluorescence in situ hybridization

1 reference

7 January 2021

Use of genetic toxicology information for risk assessment

1 reference

7 January 2021

Measurement of micronuclei in lymphocytes

1 reference

7 January 2021

Effects of high osmotic strength on chromosome aberrations, sister-chromatid exchanges and DNA strand breaks, and the relation to toxicity

1 reference

7 January 2021

A protocol for the in vitro micronucleus test. I. Contributions to the development of a protocol suitable for regulatory submissions from an examination of 16 chemicals with different mechanisms of action and different levels of activity

1 reference

7 January 2021

Recommendations for conducting the in vivo alkaline Comet assay. 4th International Comet Assay Workshop

1 reference

7 January 2021

Aspergillus nidulans: systems and results of tests for chemical induction of mitotic segregation and mutation. I. Diploid and duplication assay systems. A report of the U.S. EPA Gene-Tox Program

1 reference

7 January 2021

Recommendations for spacing of test chemical concentrations in the mouse lymphoma tk mutation assay (MLA)

1 reference

7 January 2021

Adduct formation, mutagenesis and nucleotide excision repair of DNA damage produced by reactive oxygen species and lipid peroxidation product

1 reference

7 January 2021

A comparison of micronucleus induction in 3 mouse strains with representative clastogens

1 reference

7 January 2021

Aspergillus nidulans: systems and results of tests for induction of mitotic segregation and mutation. II. Haploid assay systems and overall response of all systems. A report of the U.S. EPA Gene-Tox Program

1 reference

7 January 2021

Identifiers

DOI

10.1002/EM.20617

1 reference

23 August 2017

1 reference