(Q37824814)

23 August 2017

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title

G protein-coupled receptors: novel targets for drug discovery in cancer (English)

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G protein-coupled receptor

23 August 2017

main subject

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2

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author name string

Rosamaria Lappano

series ordinal

1

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23 August 2017

publication date

1 January 2011

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Nature Reviews Drug Discovery

23 August 2017

published in

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23 August 2017

volume

10

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23 August 2017

issue

1

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23 August 2017

page(s)

47-60

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https://scigraph.springernature.com/pub.10.1038/nrd3320

23 August 2017

exact match

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cites work

Seven-transmembrane receptors

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31 March 2020

1 reference

Identification of overexpression of orphan G protein-coupled receptor GPR49 in human colon and ovarian primary tumors

31 March 2020

1 reference

GPR87 is an overexpressed G-protein coupled receptor in squamous cell carcinoma of the lung

31 March 2020

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Mechanisms of estrogen signaling and gene expression via GPR30

31 March 2020

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GPR56 and its related diseases

31 March 2020

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G-protein-coupled receptors and cancer.

31 March 2020

1 reference

Isolation and characterization of a new cellular oncogene encoding a protein with multiple potential transmembrane domains

31 March 2020

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Angiotensin-(1-7) is an endogenous ligand for the G protein-coupled receptor Mas

31 March 2020

1 reference

Mitogenic effects of gastrin-releasing peptide in head and neck squamous cancer cells are mediated by activation of the epidermal growth factor receptor.

31 March 2020

1 reference

Organ selectivity in metastasis: regulation by chemokines and their receptors

31 March 2020

1 reference

The COX-2/PGE2 pathway: key roles in the hallmarks of cancer and adaptation to the tumour microenvironment

31 March 2020

1 reference

Chemokines in tumor-associated angiogenesis.

31 March 2020

1 reference

Gastrin-releasing peptide links stressor to cancer progression

31 March 2020

1 reference

Signal characteristics of G protein-transactivated EGF receptor

31 March 2020

1 reference

Estrogen-induced activation of Erk-1 and Erk-2 requires the G protein-coupled receptor homolog, GPR30, and occurs via trans-activation of the epidermal growth factor receptor through release of HB-EGF

31 March 2020

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New mechanisms in heptahelical receptor signaling to mitogen activated protein kinase cascades

31 March 2020

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GPCR-induced migration of breast carcinoma cells depends on both EGFR signal transactivation and EGFR-independent pathways.

31 March 2020

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Crosstalk between G-protein-coupled receptors and epidermal growth factor receptor in cancer

31 March 2020

1 reference

EGFR signal transactivation in cancer cells

31 March 2020

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ADAMs: key components in EGFR signalling and development

31 March 2020

1 reference

Cross-talk between G protein-coupled receptor and epidermal growth factor receptor signaling pathways contributes to growth and invasion of head and neck squamous cell carcinoma

31 March 2020

1 reference

Mitochondrial reactive oxygen species mediate GPCR-induced TACE/ADAM17-dependent transforming growth factor-alpha shedding

31 March 2020

1 reference

TACE cleavage of proamphiregulin regulates GPCR-induced proliferation and motility of cancer cells

31 March 2020

1 reference

The significance of cancer cell expression of the chemokine receptor CXCR4.

31 March 2020

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The CXCL12-CXCR4 chemotactic pathway as a target of adjuvant breast cancer therapies

31 March 2020

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Expression of protease-activated receptor 1 in oral squamous cell carcinoma

31 March 2020

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Aberrant Expression and Activation of the Thrombin Receptor Protease-Activated Receptor-1 Induces Cell Proliferation and Motility in Human Colon Cancer Cells

31 March 2020

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Role of thrombin in angiogenesis and tumor progression

31 March 2020

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Protease-activated receptor signalling, endocytic sorting and dysregulation in cancer

31 March 2020

1 reference

Persistent transactivation of EGFR and ErbB2/HER2 by protease-activated receptor-1 promotes breast carcinoma cell invasion

31 March 2020

1 reference

The importance of endothelin axis in initiation, progression, and therapy of ovarian cancer

31 March 2020

1 reference

Combined targeting of endothelin A receptor and epidermal growth factor receptor in ovarian cancer shows enhanced antitumor activity

31 March 2020

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Preclinical anticancer activity of the specific endothelin A receptor antagonist ZD4054.

31 March 2020

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ETAR antagonist ZD4054 exhibits additive effects with aromatase inhibitors and fulvestrant in breast cancer therapy, and improves in vivo efficacy of anastrozole

31 March 2020

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Phase 3, randomized, controlled trial of atrasentan in patients with nonmetastatic, hormone-refractory prostate cancer

31 March 2020

1 reference

Bone-specific growth inhibition of prostate cancer metastasis by atrasentan

31 March 2020

1 reference

Targeting endothelin A receptor enhances anti-proliferative and anti-invasive effects of the HER2 antibody trastuzumab in HER2-overexpressing breast cancer cells

31 March 2020

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TACE is required for the activation of the EGFR by TGF-alpha in tumors

31 March 2020

1 reference

Tackling EGFR signaling with TACE antagonists: a rational target for metalloprotease inhibitors in cancer

31 March 2020

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Novel TACE inhibitors in drug discovery: a review of patented compounds

31 March 2020

1 reference

Targeting TACE-dependent EGFR ligand shedding in breast cancer

31 March 2020

1 reference

TACE/ADAM-17: a component of the epidermal growth factor receptor axis and a promising therapeutic target in colorectal cancer

31 March 2020

1 reference

Structure-function relationship of estrogen receptor alpha and beta: impact on human health

31 March 2020

1 reference

The estrogen receptor binds tightly to its responsive element as a ligand-induced homodimer

31 March 2020

1 reference

The G protein-coupled receptor GPR30 mediates the proliferative effects induced by 17beta-estradiol and hydroxytamoxifen in endometrial cancer cells

31 March 2020

1 reference

17beta-estradiol, genistein, and 4-hydroxytamoxifen induce the proliferation of thyroid cancer cells through the g protein-coupled receptor GPR30.

31 March 2020

1 reference

G protein-coupled receptor 30 (GPR30) mediates gene expression changes and growth response to 17beta-estradiol and selective GPR30 ligand G-1 in ovarian cancer cells

31 March 2020

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The unfolding stories of GPR30, a new membrane-bound estrogen receptor.

31 March 2020

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Activation of GPR30 inhibits the growth of prostate cancer cells through sustained activation of Erk1/2, c-jun/c-fos-dependent upregulation of p21, and induction of G(2) cell-cycle arrest

31 March 2020

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Virtual and biomolecular screening converge on a selective agonist for GPR30.

31 March 2020

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G protein-coupled receptor 30 expression is up-regulated by EGF and TGF alpha in estrogen receptor alpha-positive cancer cells

31 March 2020

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Estrogenic GPR30 signalling induces proliferation and migration of breast cancer cells through CTGF

31 March 2020

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Epidermal growth factor induces G protein-coupled receptor 30 expression in estrogen receptor-negative breast cancer cells

31 March 2020

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Nuclear alternate estrogen receptor GPR30 mediates 17beta-estradiol-induced gene expression and migration in breast cancer-associated fibroblasts

31 March 2020

1 reference

31 March 2020

Fibroblasts in cancer

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The tumour microenvironment as a target for chemoprevention.

31 March 2020

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Stromal gene expression predicts clinical outcome in breast cancer

31 March 2020

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Distribution of GPR30, a seven membrane-spanning estrogen receptor, in primary breast cancer and its association with clinicopathologic determinants of tumor progression

31 March 2020

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GPR30 predicts poor survival for ovarian cancer

31 March 2020

1 reference

Crosstalk between insulin/insulin-like growth factor-1 receptors and G protein-coupled receptor signaling systems: a novel target for the antidiabetic drug metformin in pancreatic cancer

31 March 2020

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Insulin potentiates Ca2+ signaling and phosphatidylinositol 4,5-bisphosphate hydrolysis induced by Gq protein-coupled receptor agonists through an mTOR-dependent pathway

31 March 2020

1 reference

Critical nodes in signalling pathways: insights into insulin action

31 March 2020

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Systemic treatment with the antidiabetic drug metformin selectively impairs p53-deficient tumor cell growth

31 March 2020

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Metformin inhibits mammalian target of rapamycin-dependent translation initiation in breast cancer cells

31 March 2020

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Metformin disrupts crosstalk between G protein-coupled receptor and insulin receptor signaling systems and inhibits pancreatic cancer growth

31 March 2020

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Antidiabetic therapies affect risk of pancreatic cancer

31 March 2020

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Crosstalk between epidermal growth factor receptor- and insulin-like growth factor-1 receptor signaling: implications for cancer therapy.

31 March 2020

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Expression cDNA cloning of a transforming gene encoding the wild-type G alpha 12 gene product

31 March 2020

1 reference

31 March 2020

Transforming G proteins

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The G12/13-RhoA signaling pathway contributes to efficient lysophosphatidic acid-stimulated cell migration

31 March 2020

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Inhibition of tumor growth and angiogenesis by a lysophosphatidic acid antagonist in an engineered three-dimensional lung cancer xenograft model

31 March 2020

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The G protein G alpha(13) is required for growth factor-induced cell migration

31 March 2020

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Thrombin receptor overexpression in malignant and physiological invasion processes

31 March 2020

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Galpha12 and Galpha13 negatively regulate the adhesive functions of cadherin.

31 March 2020

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Role of G12 proteins in oncogenesis and metastasis

31 March 2020

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Mammalian Rho GTPases: new insights into their functions from in vivo studies

31 March 2020

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Rho GTPases in cancer cell biology

31 March 2020

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The thrombin receptor, PAR-1, causes transformation by activation of Rho-mediated signaling pathways

31 March 2020

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G protein mediated signaling pathways in lysophospholipid induced cell proliferation and survival

31 March 2020

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Role of p38 mitogen-activated kinase and c-Jun terminal kinase in migration response to lysophosphatidic acid and sphingosine-1-phosphate in glioma cells

31 March 2020

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Roles of sphingosine-1-phosphate (S1P) receptors in malignant behavior of glioma cells. Differential effects of S1P2 on cell migration and invasiveness.

31 March 2020

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S1P(2) receptors mediate inhibition of glioma cell migration through Rho signaling pathways independent of PTEN.

31 March 2020

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Cancer and the chemokine network

31 March 2020

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Involvement of chemokine receptors in breast cancer metastasis

31 March 2020

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Chemokine receptor CXCR4 downregulated by von Hippel-Lindau tumour suppressor pVHL.

31 March 2020

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Stromal cell-derived factor-1alpha promotes melanoma cell invasion across basement membranes involving stimulation of membrane-type 1 matrix metalloproteinase and Rho GTPase activities.

31 March 2020

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Activated G(alpha)13 impairs cell invasiveness through p190RhoGAP-mediated inhibition of RhoA activity.

31 March 2020

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Thrombin-activated receptors: promising targets for cancer therapy?

31 March 2020

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Twist is required for thrombin-induced tumor angiogenesis and growth

31 March 2020

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Thrombin up-regulates cathepsin D which enhances angiogenesis, growth, and metastasis

31 March 2020

1 reference

Lysophosphatidic acid receptors

31 March 2020

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Identification of p2y9/GPR23 as a Novel G Protein-coupled Receptor for Lysophosphatidic Acid, Structurally Distant from the Edg Family

31 March 2020

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GPR92 as a new G12/13- and Gq-coupled lysophosphatidic acid receptor that increases cAMP, LPA5

31 March 2020

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The orphan GPCR GPR87 was deorphanized and shown to be a lysophosphatidic acid receptor

31 March 2020

1 reference

31 March 2020

The Hallmarks of Cancer

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Differential requirement of the epidermal growth factor receptor for G protein-mediated activation of transcription factors by lysophosphatidic acid

31 March 2020

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The emerging role of lysophosphatidic acid in cancer

31 March 2020

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G protein-coupled lysophosphatidic acid receptors stimulate proliferation of colon cancer cells through the {beta}-catenin pathway

31 March 2020

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LPA2 (EDG4) mediates Rho-dependent chemotaxis with lower efficacy than LPA1 (EDG2) in breast carcinoma cells

31 March 2020

1 reference

Lysophosphatidic acid receptor 2 and Gi/Src pathway mediate cell motility through cyclooxygenase 2 expression in CAOV-3 ovarian cancer cells.

31 March 2020

1 reference

Phosphatase-resistant analogues of lysophosphatidic acid: agonists promote healing, antagonists and autotaxin inhibitors treat cancer

31 March 2020

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Alpha-substituted phosphonate analogues of lysophosphatidic acid (LPA) selectively inhibit production and action of LPA

31 March 2020

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Structure-activity relationships of fluorinated lysophosphatidic acid analogues

31 March 2020

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Serum lysophosphatidic acid is produced through diverse phospholipase pathways

31 March 2020

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Autotaxin (ATX), a potent tumor motogen, augments invasive and metastatic potential of ras-transformed cells

31 March 2020

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Inhibition of autotaxin by lysophosphatidic acid and sphingosine 1-phosphate

31 March 2020

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Lysophosphatidic acid production and action: validated targets in cancer?

31 March 2020

1 reference

Carba analogs of cyclic phosphatidic acid are selective inhibitors of autotaxin and cancer cell invasion and metastasis

31 March 2020

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Identification of small-molecule inhibitors of autotaxin that inhibit melanoma cell migration and invasion

31 March 2020

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Dual activity lysophosphatidic acid receptor pan-antagonist/autotaxin inhibitor reduces breast cancer cell migration in vitro and causes tumor regression in vivo

31 March 2020

1 reference

Hedgehog signaling in animal development: paradigms and principles

31 March 2020

1 reference

Hedgehog signaling in development and cancer.

31 March 2020

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Evaluating Smoothened as a G-protein-coupled receptor for Hedgehog signalling

31 March 2020

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GLI transcription factors: mediators of oncogenic Hedgehog signalling

31 March 2020

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Hedgehog: functions and mechanisms

31 March 2020

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Hedgehog target genes: mechanisms of carcinogenesis induced by aberrant hedgehog signaling activation

31 March 2020

1 reference

Cytotoxic effects induced by docetaxel, gefitinib, and cyclopamine on side population and nonside population cell fractions from human invasive prostate cancer cells

31 March 2020

1 reference

Expression and regulation of hedgehog signaling pathway in pancreatic cancer

31 March 2020

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Sonic hedgehog signaling promotes motility and invasiveness of gastric cancer cells through TGF-beta-mediated activation of the ALK5-Smad 3 pathway

31 March 2020

1 reference

KAAD-cyclopamine augmented TRAIL-mediated apoptosis in malignant glioma cells by modulating the intrinsic and extrinsic apoptotic pathway

31 March 2020

1 reference

Discovery of a potent and orally active hedgehog pathway antagonist (IPI-926)

31 March 2020

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An orally bioavailable small-molecule inhibitor of Hedgehog signaling inhibits tumor initiation and metastasis in pancreatic cancer.

31 March 2020

1 reference

A current review of targeted therapeutics for ovarian cancer

31 March 2020

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Inhibition of Hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer

31 March 2020

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Structural analogues of smoothened intracellular loops as potent inhibitors of Hedgehog pathway and cancer cell growth

31 March 2020

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1-amino-4-benzylphthalazines as orally bioavailable smoothened antagonists with antitumor activity

31 March 2020

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Treatment of medulloblastoma with hedgehog pathway inhibitor GDC-0449

31 March 2020

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Smoothened mutation confers resistance to a Hedgehog pathway inhibitor in medulloblastoma.

31 March 2020

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Inhibition of GLI-mediated transcription and tumor cell growth by small-molecule antagonists

31 March 2020

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Pathological responses to oncogenic Hedgehog signaling in skin are dependent on canonical Wnt/beta3-catenin signaling

31 March 2020

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31 March 2020

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Wnt/beta-catenin signaling in development and disease

31 March 2020

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Binding of GSK3beta to the APC-beta-catenin complex and regulation of complex assembly

31 March 2020

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Serine phosphorylation-regulated ubiquitination and degradation of beta-catenin

31 March 2020

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Wnt/Fz signaling and the cytoskeleton: potential roles in tumorigenesis.

31 March 2020

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MSX1 induces the Wnt pathway antagonist genes DKK1, DKK2, DKK3, and SFRP1 in neuroblastoma cells, but does not block Wnt3 and Wnt5A signalling to DVL3.

31 March 2020

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Wnt signaling: complexity at the surface.

31 March 2020

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Frizzled-7 dictates three-dimensional organization of colorectal cancer cell carcinoids

31 March 2020

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Anticancer activity of BIM-46174, a new inhibitor of the heterotrimeric Galpha/Gbetagamma protein complex

31 March 2020

1 reference

Activation of the non-canonical Dvl-Rac1-JNK pathway by Frizzled homologue 10 in human synovial sarcoma

31 March 2020

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Down-regulation of frizzled-7 expression decreases survival, invasion and metastatic capabilities of colon cancer cells

31 March 2020

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LRP6 overexpression defines a class of breast cancer subtype and is a target for therapy

31 March 2020

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Wnt signaling in breast cancer: have we come full circle?

31 March 2020

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Mining the Wnt pathway for cancer therapeutics

31 March 2020

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Quercetin inhibit human SW480 colon cancer growth in association with inhibition of cyclin D1 and survivin expression through Wnt/beta-catenin signaling pathway

31 March 2020

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Ethacrynic acid exhibits selective toxicity to chronic lymphocytic leukemia cells by inhibition of the Wnt/beta-catenin pathway

31 March 2020

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Murrayafoline A attenuates the Wnt/beta-catenin pathway by promoting the degradation of intracellular beta-catenin proteins.

31 March 2020

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Thiazolidinediones downregulate Wnt/beta-catenin signaling via multiple mechanisms in breast cancer cells.

31 March 2020

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Drugging the Wnt pathway: problems and progress.

31 March 2020

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G-protein-coupled receptors and signaling networks: emerging paradigms.

31 March 2020

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CXCR4 is a major chemokine receptor on glioma cells and mediates their survival.

31 March 2020

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Akt activation induced by lysophosphatidic acid and sphingosine-1-phosphate requires both mitogen-activated protein kinase kinase and p38 mitogen-activated protein kinase and is cell-line specific

31 March 2020

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Dual actions of sphingosine-1-phosphate: extracellular through the Gi-coupled receptor Edg-1 and intracellular to regulate proliferation and survival

31 March 2020

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Caspase activation during phorbol ester-induced apoptosis requires ROCK-dependent myosin-mediated contraction

31 March 2020

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A hallmark of immunoreceptor, the tyrosine-based inhibitory motif ITIM, is present in the G protein-coupled receptor OX1R for orexins and drives apoptosis: a novel mechanism.

31 March 2020

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Adaptor protein-2 interaction with arrestin regulates GPCR recycling and apoptosis

31 March 2020

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p53: traffic cop at the crossroads of DNA repair and recombination

31 March 2020

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Importance of p53 for cancer onset and therapy

31 March 2020

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The G protein-coupled receptor 87 is necessary for p53-dependent cell survival in response to genotoxic stress

31 March 2020

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Lysophosphatidic acid decreases the nuclear localization and cellular abundance of the p53 tumor suppressor in A549 lung carcinoma cells

31 March 2020

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G-protein-coupled receptor kinase 5 phosphorylates p53 and inhibits DNA damage-induced apoptosis

31 March 2020

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p53 Attenuates cancer cell migration and invasion through repression of SDF-1/CXCL12 expression in stromal fibroblasts

31 March 2020

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G protein-coupled receptor connectivity to NF-kappaB in inflammation and cancer

31 March 2020

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Is NF-kappaB a good target for cancer therapy? Hopes and pitfalls

31 March 2020

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Control of inducible chemoresistance: enhanced anti-tumor therapy through increased apoptosis by inhibition of NF-kappaB

31 March 2020

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NF-kappaB as a potential molecular target for cancer therapy

31 March 2020

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Bcl10 plays a critical role in NF-kappaB activation induced by G protein-coupled receptors.

31 March 2020

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CARMA3 deficiency abrogates G protein-coupled receptor-induced NF-{kappa}B activation

31 March 2020

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Beta-arrestin 2 is required for lysophosphatidic acid-induced NF-kappaB activation

31 March 2020

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Local angiotensin II-generation in human gastric cancer: correlation with tumor progression through the activation of ERK1/2, NF-kappaB and survivin

31 March 2020

1 reference

CF101, an agonist to the A3 adenosine receptor, enhances the chemotherapeutic effect of 5-fluorouracil in a colon carcinoma murine model

31 March 2020

1 reference

An agonist to the A3 adenosine receptor inhibits colon carcinoma growth in mice via modulation of GSK-3 beta and NF-kappa B.

31 March 2020

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Identification of herpesvirus-like DNA sequences in AIDS-associated Kaposi's sarcoma

31 March 2020

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The Kaposi's sarcoma-associated herpesvirus G protein-coupled receptor as a therapeutic target for the treatment of Kaposi's sarcoma.

31 March 2020

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The N terminus of Kaposi's sarcoma-associated herpesvirus G protein-coupled receptor is necessary for high affinity chemokine binding but not for constitutive activity.

31 March 2020

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Tumorigenesis induced by the HHV8-encoded chemokine receptor requires ligand modulation of high constitutive activity.

31 March 2020

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Kaposi's sarcoma-associated herpesvirus K7 induces viral G protein-coupled receptor degradation and reduces its tumorigenicity

31 March 2020

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G-protein-coupled receptor of Kaposi's sarcoma-associated herpesvirus is a viral oncogene and angiogenesis activator

31 March 2020

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Transgenic expression of the chemokine receptor encoded by human herpesvirus 8 induces an angioproliferative disease resembling Kaposi's sarcoma

31 March 2020

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Endothelial infection with KSHV genes in vivo reveals that vGPCR initiates Kaposi's sarcomagenesis and can promote the tumorigenic potential of viral latent genes

31 March 2020

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1 Alpha,25-dihydroxyvitamin D3 and its TX527 analog inhibit the growth of endothelial cells transformed by Kaposi sarcoma-associated herpes virus G protein-coupled receptor in vitro and in vivo.

31 March 2020

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Oncogenic gamma-herpesviruses: comparison of viral proteins involved in tumorigenesis

31 March 2020

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Epstein-Barr virus-encoded BILF1 is a constitutively active G protein-coupled receptor

31 March 2020

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The Epstein-Barr virus BILF1 gene encodes a G protein-coupled receptor that inhibits phosphorylation of RNA-dependent protein kinase

31 March 2020

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Immune responses to Epstein-Barr virus: molecular interactions in the virus evasion of CD8+ T cell immunity

31 March 2020

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Detection of human cytomegalovirus genome and gene products in central nervous system tumours

31 March 2020

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Specific localisation of human cytomegalovirus nucleic acids and proteins in human colorectal cancer

31 March 2020

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HCMV microinfections in inflammatory diseases and cancer

31 March 2020

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Oncomodulatory signals by regulatory proteins encoded by human cytomegalovirus: a novel role for viral infection in tumor progression

31 March 2020

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Cytomegalovirus infection blocks apoptosis in cancer cells.

31 March 2020

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Human cytomegalovirus-encoded chemokine receptor US28 promotes tumorigenesis.

31 March 2020

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The human cytomegalovirus-encoded chemokine receptor US28 promotes angiogenesis and tumor formation via cyclooxygenase-2.

31 March 2020

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From purified GPCRs to drug discovery: the promise of protein-based methodologies

31 March 2020

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The impact of GPCR structures on pharmacology and structure-based drug design

31 March 2020

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Insights into G protein structure, function, and regulation.

31 March 2020

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Regulator of G-protein signaling (RGS) proteins in cancer biology

31 March 2020

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Regulator of G-protein signalling expression and function in ovarian cancer cell lines.

31 March 2020

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Modulation of g protein signaling normalizes tumor vessels

31 March 2020

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The G protein-coupled receptor kinase (GRK) interactome: role of GRKs in GPCR regulation and signaling

31 March 2020

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Beyond desensitization: physiological relevance of arrestin-dependent signaling.

31 March 2020

1 reference

Regulation of GPR54 signaling by GRK2 and {beta}-arrestin

31 March 2020

1 reference

Role for the regulator of G-protein signaling homology domain of G protein-coupled receptor kinases 5 and 6 in beta 2-adrenergic receptor and rhodopsin phosphorylation

31 March 2020

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The Epstein-Barr virus G-protein-coupled receptor contributes to immune evasion by targeting MHC class I molecules for degradation

31 March 2020

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12 December 2020

G proteins in cancer: the prostate cancer paradigm

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12 December 2020

Overexpression of G protein-coupled receptors in cancer cells: involvement in tumor progression

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12 December 2020

Hedgehog beyond medulloblastoma and basal cell carcinoma

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12 December 2020

Virus-encoded G-protein-coupled receptors: constitutively active (dys)regulators of cell function and their potential as drug target

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12 December 2020

The Wnt signaling pathway and its role in tumor development

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12 December 2020

Bradykinin enhances cell migration in human chondrosarcoma cells through BK receptor signaling pathways

1 reference

12 December 2020

Lysophosphatidic acid prevents apoptosis in fibroblasts via G(i)-protein-mediated activation of mitogen-activated protein kinase

1 reference

12 December 2020

Cyclopamine and quercetin suppress the growth of leukemia and lymphoma cells

1 reference

12 December 2020

Role of Hedgehog signaling pathway in proliferation and invasiveness of hepatocellular carcinoma cells.

1 reference

12 December 2020

Expression of the open reading frame 74 (G-protein-coupled receptor) gene of Kaposi's sarcoma (KS)-associated herpesvirus: implications for KS pathogenesis

1 reference

12 December 2020

Rho GTPases in hepatocellular carcinoma

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12 December 2020

GPR30: a novel indicator of poor survival for endometrial carcinoma

1 reference

12 December 2020

Metformin regulates breast cancer stem cell ontogeny by transcriptional regulation of the epithelial-mesenchymal transition (EMT) status.

1 reference

12 December 2020

The Kaposi's sarcoma-associated herpes virus G protein-coupled receptor up-regulates vascular endothelial growth factor expression and secretion through mitogen-activated protein kinase and p38 pathways acting on hypoxia-inducible factor 1alpha

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12 December 2020

Identifiers

DOI

10.1038/NRD3320

1 reference

23 August 2017

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