(Q37880729)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21618531%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

review article

1 reference

title

Molecular chaperones as therapeutic targets to counteract proteostasis defects (English)

1 reference

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2 February 2020

0 references

1

1 reference

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2 February 2020

Roberto Dominici

2

1 reference

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2 February 2020

author name string

Marina Cardano

3

1 reference

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2 February 2020

Giuseppe Diaferia

4

1 reference

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2 February 2020

Ermanna Rovida

5

1 reference

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2 February 2020

Ida Biunno

6

1 reference

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2 February 2020

publication date

1 March 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21618531%20AND%20SRC:MED&resulttype=core&format=json

Journal of Cellular Physiology

2 February 2020

published in

1 reference

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2 February 2020

volume

227

1 reference

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2 February 2020

issue

3

1 reference

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2 February 2020

page(s)

1226-1234

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21618531%20AND%20SRC:MED&resulttype=core&format=json

Initial hydrophobic collapse in the folding of barstar

2 February 2020

cites work

1 reference

Principles that govern the folding of protein chains

21 January 2018

1 reference

The aggravating role of the ubiquitin-proteasome system in neurodegeneration

21 January 2018

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Chaperone-targeting cytotoxin and endoplasmic reticulum stress-inducing drug synergize to kill cancer cells

21 January 2018

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A migration signature and plasma biomarker panel for pancreatic adenocarcinoma

21 January 2018

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Is protein folding hierarchic? II. Folding intermediates and transition states

21 January 2018

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SEL1L a multifaceted protein playing a role in tumor progression.

21 January 2018

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Heat shock proteins in cancer: chaperones of tumorigenesis

21 January 2018

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mSEL-1L (Suppressor/enhancer Lin12-like) protein levels influence murine neural stem cell self-renewal and lineage commitment

21 January 2018

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Identification of a region within SEL1L protein required for tumour growth inhibition

21 January 2018

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Secretion of novel SEL1L endogenous variants is promoted by ER stress/UPR via endosomes and shed vesicles in human cancer cells

21 January 2018

1 reference

SEL1L expression in pancreatic adenocarcinoma parallels SMAD4 expression and delays tumor growth in vitro and in vivo

21 January 2018

1 reference

The carboxy-terminal domain of Hsc70 provides binding sites for a distinct set of chaperone cofactors

21 January 2018

1 reference

The protein folding problem: when will it be solved?

21 January 2018

1 reference

The protein folding problem

21 January 2018

1 reference

SEL1L expression in non-small cell lung cancer.

21 January 2018

1 reference

Protein folding and unfolding at atomic resolution

21 January 2018

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Disease-modifying pathways in neurodegeneration.

21 January 2018

1 reference

Haploid insufficiency of suppressor enhancer Lin12 1-like (SEL1L) protein predisposes mice to high fat diet-induced hyperglycemia.

21 January 2018

1 reference

Heat shock transcription factor 1-activating compounds suppress polyglutamine-induced neurodegeneration through induction of multiple molecular chaperones

21 January 2018

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Heat shock proteins 27 and 70: anti-apoptotic proteins with tumorigenic properties

21 January 2018

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SEL1L and squamous cell carcinoma of the esophagus.

21 January 2018

1 reference

Inactivation of VCP/ter94 suppresses retinal pathology caused by misfolded rhodopsin in Drosophila

21 January 2018

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Converging concepts of protein folding in vitro and in vivo

21 January 2018

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Quality and quantity control at the endoplasmic reticulum

21 January 2018

1 reference

Small molecule inducers of heat-shock response reduce polyQ-mediated huntingtin aggregation. A possible therapeutic strategy.

21 January 2018

1 reference

Adaptation to ER stress as a driver of malignancy and resistance to therapy in human melanoma

21 January 2018

1 reference

Hip, a novel cochaperone involved in the eukaryotic hsc70/hsp40 reaction cycle

21 January 2018

1 reference

Cell Biology. The proteome in balance

21 January 2018

1 reference

Reduced histone deacetylase 7 activity restores function to misfolded CFTR in cystic fibrosis

21 January 2018

1 reference

Molecular chaperones as rational drug targets for Parkinson's disease therapeutics

21 January 2018

1 reference

Protein structure prediction on the Web: a case study using the Phyre server

21 January 2018

1 reference

Sub-microsecond protein folding

21 January 2018

1 reference

Correctors promote folding of the CFTR in the endoplasmic reticulum.

21 January 2018

1 reference

Collective roles of molecular chaperones in protein degradation pathways associated with neurodegenerative diseases

21 January 2018

1 reference

The crystal structure of Helicobacter pylori cysteine-rich protein B reveals a novel fold for a penicillin-binding protein

21 January 2018

1 reference

The crystal structure of Helicobacter cysteine-rich protein C at 2.0 A resolution: similar peptide-binding sites in TPR and SEL1-like repeat proteins

21 January 2018

1 reference

Chaperone-mediated autophagy in aging and disease

21 January 2018

1 reference

CHIP: a link between the chaperone and proteasome systems

21 January 2018

1 reference

Role of molecular chaperones in neurodegenerative disorders

21 January 2018

1 reference

Proteotoxic stress and inducible chaperone networks in neurodegenerative disease and aging

21 January 2018

1 reference

Partial restoration of mutant enzyme homeostasis in three distinct lysosomal storage disease cell lines by altering calcium homeostasis

21 January 2018

1 reference

Chemical and biological approaches synergize to ameliorate protein-folding diseases.

21 January 2018

1 reference

Aggresome formation and neurodegenerative diseases: therapeutic implications

21 January 2018

1 reference

A soluble sulfogalactosyl ceramide mimic promotes Delta F508 CFTR escape from endoplasmic reticulum associated degradation

21 January 2018

1 reference

Heat shock protein hsp72 is a negative regulator of apoptosis signal-regulating kinase 1.

21 January 2018

1 reference

Targeting of multiple signalling pathways by heat shock protein 90 molecular chaperone inhibitors

21 January 2018

1 reference

Identification and structural characterization of the ATP/ADP-binding site in the Hsp90 molecular chaperone

21 January 2018

1 reference

Brain-permeable small-molecule inhibitors of Hsp90 prevent alpha-synuclein oligomer formation and rescue alpha-synuclein-induced toxicity

21 January 2018

1 reference

The unfolded protein response regulator GRP78/BiP as a novel target for increasing chemosensitivity in malignant gliomas.

21 January 2018

1 reference

Dislocation of ricin toxin A chains in human cells utilizes selective cellular factors

21 January 2018

1 reference

What are pharmacological chaperones and why are they interesting?

21 January 2018

1 reference

Signal integration in the endoplasmic reticulum unfolded protein response

21 January 2018

1 reference

Trehalose, a novel mTOR-independent autophagy enhancer, accelerates the clearance of mutant huntingtin and alpha-synuclein.

21 January 2018

1 reference

Chemical chaperones increase the cellular activity of N370S beta -glucosidase: a therapeutic strategy for Gaucher disease

21 January 2018

1 reference

Activation and clinical significance of the unfolded protein response in breast cancer

21 January 2018

1 reference

An acetylation site in the middle domain of Hsp90 regulates chaperone function

21 January 2018

1 reference

Geldanamycin induces heat shock protein 70 and protects against MPTP-induced dopaminergic neurotoxicity in mice

21 January 2018

1 reference

Geldanamycin activates a heat shock response and inhibits huntingtin aggregation in a cell culture model of Huntington's disease

21 January 2018

1 reference

Recognition of an ERAD-L substrate analyzed by site-specific in vivo photocrosslinking

21 January 2018

1 reference

Molecular chaperone targeting and regulation by BAG family proteins

21 January 2018

1 reference

Trehalose alleviates polyglutamine-mediated pathology in a mouse model of Huntington disease

21 January 2018

1 reference

Targeting cancer cells through autophagy for anticancer therapy

21 January 2018

1 reference

Multiple routes and structural heterogeneity in protein folding

21 January 2018

1 reference

Selective inhibition of endoplasmic reticulum-associated degradation rescues DeltaF508-cystic fibrosis transmembrane regulator and suppresses interleukin-8 levels: therapeutic implications.

21 January 2018

1 reference

Molecular simulation of ab initio protein folding for a millisecond folder NTL9(1-39)

21 January 2018

1 reference

Additive effect of multiple pharmacological chaperones on maturation of CFTR processing mutants

21 January 2018

1 reference

HSP90 and the chaperoning of cancer

21 January 2018

1 reference

Pharmacologic chaperoning as a strategy to treat Gaucher disease

21 January 2018

1 reference