(Q37899566)

30 June 2019

review article

1 reference

title

Dynamic allostery: linkers are not merely flexible (English)

1 reference

30 June 2019

author

Buyong Ma

series ordinal

1

1 reference

25 August 2017

4

Ruth Nussinov

1 reference

25 August 2017

2

Chung-Jung Tsai

1 reference

30 June 2019

Türkan Haliloğlu

series ordinal

3

object named as

Türkan Haliloğlu

1 reference

30 June 2019

publication date

1 July 2011

1 reference

30 June 2019

published in

Structure

1 reference

30 June 2019

volume

19

1 reference

30 June 2019

issue

7

1 reference

30 June 2019

page(s)

907-917

1 reference

30 June 2019

Identity between TRAP and SMCC complexes indicates novel pathways for the function of nuclear receptors and diverse mammalian activators

cites work

1 reference

12 December 2020

Folding funnels, binding funnels, and protein function

1 reference

12 December 2020

Detecting protein function and protein-protein interactions from genome sequences

1 reference

12 December 2020

Folding and binding cascades: shifts in energy landscapes

1 reference

12 December 2020

Folding funnels and binding mechanisms

1 reference

12 December 2020

Transcriptional activation by Gcn4p involves independent interactions with the SWI/SNF complex and the SRB/mediator

1 reference

12 December 2020

Origin of multicellular eukaryotes - insights from proteome comparisons.

1 reference

12 December 2020

Role of linkers in communication between protein modules

1 reference

12 December 2020

Insights into SCF ubiquitin ligases from the structure of the Skp1-Skp2 complex

1 reference

12 December 2020

Two-state allosteric behavior in a single-domain signaling protein

1 reference

12 December 2020

Structured disorder and conformational selection

1 reference

12 December 2020

The TRAP/Mediator coactivator complex interacts directly with estrogen receptors alpha and beta through the TRAP220 subunit and directly enhances estrogen receptor function in vitro

1 reference

12 December 2020

Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complex

1 reference

12 December 2020

TRAP/SMCC/mediator-dependent transcriptional activation from DNA and chromatin templates by orphan nuclear receptor hepatocyte nuclear factor 4.

1 reference

12 December 2020

An analysis of protein domain linkers: their classification and role in protein folding

1 reference

12 December 2020

A multiplicity of coactivators is required by Gcn4p at individual promoters in vivo

1 reference

12 December 2020

Organization of cell-regulatory systems through modular-protein-interaction domains

1 reference

12 December 2020

Coordination of p300-mediated chromatin remodeling and TRAP/mediator function through coactivator PGC-1alpha

1 reference

12 December 2020

Multi-domain protein families and domain pairs: comparison with known structures and a random model of domain recombination.

1 reference

12 December 2020

The role of dynamics in allosteric regulation

1 reference

12 December 2020

A triad of subunits from the Gal11/tail domain of Srb mediator is an in vivo target of transcriptional activator Gcn4p

1 reference

12 December 2020

Structural and functional organization of TRAP220, the TRAP/mediator subunit that is targeted by nuclear receptors

1 reference

12 December 2020

The SCF ubiquitin ligase: insights into a molecular machine

1 reference

12 December 2020

Is allostery an intrinsic property of all dynamic proteins?

1 reference

12 December 2020

A high resolution protein interaction map of the yeast Mediator complex

1 reference

12 December 2020

Control of protein functional dynamics by peptide linkers.

1 reference

12 December 2020

MED14 and MED1 differentially regulate target-specific gene activation by the glucocorticoid receptor

1 reference

12 December 2020

Coupled protein domain motion in Taq polymerase revealed by neutron spin-echo spectroscopy

1 reference

12 December 2020

cAMP is a ligand for the tandem GAF domain of human phosphodiesterase 10 and cGMP for the tandem GAF domain of phosphodiesterase 11

1 reference

12 December 2020

Structural changes involved in protein binding correlate with intrinsic motions of proteins in the unbound state

1 reference

12 December 2020

The changing landscape of protein allostery

1 reference

12 December 2020

Reconciling the "old" and "new" views of protein allostery: a molecular simulation study of chemotaxis Y protein (CheY).

1 reference

12 December 2020

Regulation of Aurora-A kinase gene expression via GABP recruitment of TRAP220/MED1.

1 reference

12 December 2020

The dynamic energy landscape of dihydrofolate reductase catalysis

1 reference

12 December 2020

The mediator complex functions as a coactivator for GATA-1 in erythropoiesis via subunit Med1/TRAP220

1 reference

12 December 2020

The Energy Landscapes and Motions of Proteins

1 reference

12 December 2020

Binding induced conformational changes of proteins correlate with their intrinsic fluctuations: a case study of antibodies

1 reference

12 December 2020

MED25 is distinct from TRAP220/MED1 in cooperating with CBP for retinoid receptor activation

1 reference

12 December 2020

Structural dynamics in the gating ring of cyclic nucleotide-gated ion channels

1 reference

12 December 2020

The Mediator subunit MED1/TRAP220 is required for optimal glucocorticoid receptor-mediated transcription activation

1 reference

12 December 2020

Alternative mechanisms by which mediator subunit MED1/TRAP220 regulates peroxisome proliferator-activated receptor gamma-stimulated adipogenesis and target gene expression

1 reference

12 December 2020

Evolution of allostery in the cyclic nucleotide binding module

1 reference

12 December 2020

The Med1 subunit of transcriptional mediator plays a central role in regulating CCAAT/enhancer-binding protein-beta-driven transcription in response to interferon-gamma

1 reference

12 December 2020

Allostery: absence of a change in shape does not imply that allostery is not at play

1 reference

12 December 2020

RAM-induced Allostery Facilitates Assembly of a Notch Pathway Active Transcription Complex

1 reference

12 December 2020

Discrete breathers in protein structures

1 reference

12 December 2020

Allostery and cooperativity revisited

1 reference

12 December 2020

Subdividing repressor function: DNA binding affinity, selectivity, and allostery can be altered by amino acid substitution of nonconserved residues in a LacI/GalR homologue

1 reference

12 December 2020

Functional chimeras of the phosphodiesterase 5 and 10 tandem GAF domains

1 reference

12 December 2020

Allosteric regulation and catalysis emerge via a common route.

1 reference

12 December 2020

Light-activated DNA binding in a designed allosteric protein

1 reference

12 December 2020

Dynamic energy landscape view of coupled binding and protein conformational change: induced-fit versus population-shift mechanisms

1 reference

12 December 2020

Structural insights into NEDD8 activation of cullin-RING ligases: conformational control of conjugation

1 reference

12 December 2020

The Kv1.2 potassium channel: the position of an N-glycan on the extracellular linkers affects its protein expression and function

1 reference

12 December 2020

Direct observation of the dynamic process underlying allosteric signal transmission.

1 reference

12 December 2020

Protein allostery, signal transmission and dynamics: a classification scheme of allosteric mechanisms

1 reference

12 December 2020

Analysis of correlations between energy and residue fluctuations in native proteins and determination of specific sites for binding.

1 reference

12 December 2020

The c-terminus of GRK3 indicates rapid dissociation of G protein heterotrimers

1 reference

12 December 2020

Structural basis for cAMP-mediated allosteric control of the catabolite activator protein.

1 reference

12 December 2020

A genomic strategy to elucidate modules of oncogenic pathway signaling networks

1 reference

12 December 2020

DNA Binding Site Sequence Directs Glucocorticoid Receptor Structure and Activity

1 reference

12 December 2020

Mechanism of differential control of NMDA receptor activity by NR2 subunits

1 reference

12 December 2020

Energy landscape along an enzymatic reaction trajectory: hinges or cracks?

1 reference

12 December 2020

Amplification of signaling via cellular allosteric relay and protein disorder

1 reference

12 December 2020

Allosteric Effects Govern Nuclear Receptor Action: DNA Appears as a Player

1 reference

12 December 2020

Arsenic metalation of seaweed Fucus vesiculosus metallothionein: the importance of the interdomain linker in metallothionein

1 reference

12 December 2020

The origin of allosteric functional modulation: multiple pre-existing pathways

1 reference

12 December 2020

The mechanism of ubiquitination in the cullin-RING E3 ligase machinery: conformational control of substrate orientation

1 reference

12 December 2020

Mechanism for the allosteric regulation of phosphodiesterase 2A deduced from the X-ray structure of a near full-length construct

1 reference

12 December 2020

Hidden dynamic allostery in a PDZ domain.

1 reference

12 December 2020

The role of dynamic conformational ensembles in biomolecular recognition

1 reference

12 December 2020

Observing biological dynamics at atomic resolution using NMR.

1 reference

12 December 2020

Long-range energy transfer in proteins

1 reference

12 December 2020

Dynamic activation of an allosteric regulatory protein.

1 reference

12 December 2020

During transitions proteins make fleeting bonds.

1 reference

12 December 2020

Transient non-native hydrogen bonds promote activation of a signaling protein

1 reference

12 December 2020

Millisecond timescale fluctuations in dihydrofolate reductase are exquisitely sensitive to the bound ligands

1 reference

12 December 2020

Molecular dynamics reveal the essential role of linker motions in the function of cullin-RING E3 ligases

1 reference

12 December 2020

Macromolecular dynamics in crowded environments

1 reference

12 December 2020

Entropic mechanism of large fluctuation in allosteric transition

1 reference

12 December 2020

Seven transmembrane receptors as shapeshifting proteins: the impact of allosteric modulation and functional selectivity on new drug discovery

1 reference

12 December 2020

Rapid diversification of cell signaling phenotypes by modular domain recombination

1 reference

12 December 2020

p53 activates transcription by directing structural shifts in Mediator

1 reference

12 December 2020

Neck linker length determines the degree of processivity in kinesin-1 and kinesin-2 motors

1 reference

12 December 2020

Independent and cooperative motions of the Kv1.2 channel: voltage sensing and gating

1 reference

12 December 2020

The N terminus of Cbl-c regulates ubiquitin ligase activity by modulating affinity for the ubiquitin-conjugating enzyme

1 reference

12 December 2020

Induced fit, conformational selection and independent dynamic segments: an extended view of binding events

1 reference

12 December 2020

Rbx1 flexible linker facilitates cullin-RING ligase function before neddylation and after deneddylation

1 reference

12 December 2020

An adaptable peptide-based porous material

1 reference

12 December 2020

Protein functional landscapes, dynamics, allostery: a tortuous path towards a universal theoretical framework.

1 reference

12 December 2020

Choreographing an enzyme's dance

1 reference

12 December 2020

Enzyme dynamics point to stepwise conformational selection in catalysis.

1 reference

12 December 2020

Identification of an allosteric signaling network within Tec family kinases

1 reference

12 December 2020

Biochemical characterization of the transcriptional regulator BzdR from Azoarcus sp. CIB

1 reference

12 December 2020

Crystallographic and Nuclear Magnetic Resonance Evaluation of the Impact of Peptide Binding to the Second PDZ Domain of Protein Tyrosine Phosphatase 1E

1 reference

12 December 2020

G protein coupled receptors as allosteric proteins and the role of allosteric modulators

1 reference

12 December 2020

An interdomain sector mediating allostery in Hsp70 molecular chaperones

1 reference

12 December 2020

Allostery and population shift in drug discovery

1 reference

12 December 2020

Impact of linker length on the activity of PROTACs

1 reference

12 December 2020

Coupling of receptor conformation and ligand orientation determine graded activity

1 reference

12 December 2020

Coupling of tandem Smad ubiquitination regulatory factor (Smurf) WW domains modulates target specificity

1 reference

12 December 2020

Regulation of Syk by phosphorylation on serine in the linker insert

1 reference

12 December 2020

ASD: a comprehensive database of allosteric proteins and modulators

1 reference

12 December 2020

The O-glycosylated linker from the Trichoderma reesei Family 7 cellulase is a flexible, disordered protein

1 reference

12 December 2020

Sequences at the interface of the fifth immunoglobulin domain and first fibronectin type III repeat of the neural cell adhesion molecule are critical for its polysialylation

1 reference

12 December 2020

Mesoscopic dynamics of diffusion-influenced enzyme kinetics

1 reference

12 December 2020

Structure and mechanism of the hexameric MecA-ClpC molecular machine

1 reference

12 December 2020

Functionally important positions can comprise the majority of a protein's architecture

1 reference

12 December 2020

NMR reveals novel mechanisms of protein activity regulation

1 reference

12 December 2020

Regulation of membrane traffic by integrin signaling

1 reference

12 December 2020

Dynamically committed, uncommitted, and quenched states encoded in protein kinase A revealed by NMR spectroscopy

1 reference

12 December 2020

Structural insights into the architecture and allostery of full-length AMP-activated protein kinase.

1 reference

12 December 2020

Allosteric signal transmission in the nucleotide-binding domain of 70-kDa heat shock protein (Hsp70) molecular chaperones

1 reference

12 December 2020

Processes of fungal proteome evolution and gain of function: gene duplication and domain rearrangement

1 reference

12 December 2020

Crystal structure of Thermus aquaticus DNA polymerase

1 reference

12 December 2020

Structure of Taq polymerase with DNA at the polymerase active site

1 reference

12 December 2020

Crystal structure of Taq DNA polymerase in complex with an inhibitory Fab: the Fab is directed against an intermediate in the helix-coil dynamics of the enzyme

1 reference

12 December 2020

10.1016/J.STR.2011.06.002

Identifiers

DOI

1 reference

30 June 2019

PMCID

6361528

1 reference

30 June 2019

PubMed ID

21742258

1 reference

30 June 2019