(Q37953288)

25 August 2017

Parkin, PINK1 and mitochondrial integrity: emerging concepts of mitochondrial dysfunction in Parkinson's disease (English)

1 reference

25 August 2017

1 reference

1 reference

Konstanze F Winklhofer

series ordinal

2

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author name string

Anna Pilsl

series ordinal

1

1 reference

25 August 2017

6 November 2011

1 reference

25 August 2017

Acta Neuropathologica

1 reference

25 August 2017

123

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25 August 2017

2

1 reference

25 August 2017

173-188

1 reference

https://scigraph.springernature.com/pub.10.1007/s00401-011-0902-3

25 August 2017

0 references

cites work

Expanding insights of mitochondrial dysfunction in Parkinson's disease.

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OPA1, encoding a dynamin-related GTPase, is mutated in autosomal dominant optic atrophy linked to chromosome 3q28

21 January 2018

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Constructing and decoding unconventional ubiquitin chains.

21 January 2018

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Mutations in PTEN-induced putative kinase 1 associated with recessive parkinsonism have differential effects on protein stability

21 January 2018

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Mitochondrial fusion and division: Regulation and role in cell viability

21 January 2018

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Parkin selectively alters the intrinsic threshold for mitochondrial cytochrome c release

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Genetic findings in Parkinson's disease and translation into treatment: a leading role for mitochondria?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Parkin is transcriptionally regulated by ATF4: evidence for an interconnection between mitochondrial stress and ER stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Staging of brain pathology related to sporadic Parkinson's disease

21 January 2018

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Mitochondrial dynamics, cell death and the pathogenesis of Parkinson's disease

21 January 2018

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Balance is the challenge--the impact of mitochondrial dynamics in Parkinson's disease

21 January 2018

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A critical evaluation of the Braak staging scheme for Parkinson's disease.

21 January 2018

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Protofibrils, pores, fibrils, and neurodegeneration: separating the responsible protein aggregates from the innocent bystanders

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

The WD-repeats of Net2p interact with Dnm1p and Fis1p to regulate division of mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Parkin negatively regulates JNK pathway in the dopaminergic neurons of Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Broad activation of the ubiquitin-proteasome system by Parkin is critical for mitophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Rapid ATP loss caused by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mouse brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Mitochondrial dynamics--fusion, fission, movement, and mitophagy--in neurodegenerative diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Disruption of fusion results in mitochondrial heterogeneity and dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Mitochondrial fusion protects against neurodegeneration in the cerebellum.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Mitochondrial fusion is required for mtDNA stability in skeletal muscle and tolerance of mtDNA mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

A pivotal role for PINK1 and autophagy in mitochondrial quality control: implications for Parkinson disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

S-nitrosylation of parkin regulates ubiquitination and compromises parkin's protective function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Perturbations in mitochondrial dynamics induced by human mutant PINK1 can be rescued by the mitochondrial division inhibitor mdivi-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Loss of PINK1 function promotes mitophagy through effects on oxidative stress and mitochondrial fission

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Parkin prevents mitochondrial swelling and cytochrome c release in mitochondria-dependent cell death.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Chronic parkinsonism secondary to intravenous injection of meperidine analogues

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

The role of parkin in familial and sporadic Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Genetic animal models of Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

PINK1 cleavage at position A103 by the mitochondrial protease PARL.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

PINK1 function in health and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Nuclear gene OPA1, encoding a mitochondrial dynamin-related protein, is mutated in dominant optic atrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

The Parkinson's disease genes pink1 and parkin promote mitochondrial fission and/or inhibit fusion in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Functions and dysfunctions of mitochondrial dynamics

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Nix is critical to two distinct phases of mitophagy, reactive oxygen species-mediated autophagy induction and Parkin-ubiquitin-p62-mediated mitochondrial priming

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Progressive parkinsonism in mice with respiratory-chain-deficient dopamine neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Autophagy: a lysosomal degradation pathway with a central role in health and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Loss-of-function of human PINK1 results in mitochondrial pathology and can be rescued by parkin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

A regulated interaction with the UIM protein Eps15 implicates parkin in EGF receptor trafficking and PI(3)K-Akt signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Parkin is protective against proteotoxic stress in a transgenic zebrafish model

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

PINK1-associated Parkinson's disease is caused by neuronal vulnerability to calcium-induced cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Autophagy, a guardian against neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Loss of PINK1 causes mitochondrial functional defects and increased sensitivity to oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Mitofusin 1 and mitofusin 2 are ubiquitinated in a PINK1/parkin-dependent manner upon induction of mitophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

The PINK1/Parkin-mediated mitophagy is compromised by PD-associated mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Parkinson phenotype in aged PINK1-deficient mice is accompanied by progressive mitochondrial dysfunction in absence of neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Parkin promotes the ubiquitination and degradation of the mitochondrial fusion factor mitofusin 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

During autophagy mitochondria elongate, are spared from degradation and sustain cell viability.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Mitochondrial pathology and apoptotic muscle degeneration in Drosophila parkin mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Differential effects of PINK1 nonsense and missense mutations on mitochondrial function and morphology.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Mutant Parkin impairs mitochondrial function and morphology in human fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Cytoplasmic Pink1 activity protects neurons from dopaminergic neurotoxin MPTP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Genetic analysis of pathways to Parkinson disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

The genetics of Parkinson's syndromes: a critical review

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Parkin protects against tyrosinase-mediated dopamine neurotoxicity by suppressing stress-activated protein kinase pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Mitochondrial biology and oxidative stress in Parkinson disease pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Parkin mediates neuroprotection through activation of IkappaB kinase/nuclear factor-kappaB signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Parkin attenuates manganese-induced dopaminergic cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Mitochondrial dysfunction, peroxidation damage and changes in glutathione metabolism in PARK6.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

The molecular mechanism of mitochondrial fusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Identification of a novel Zn2+-binding domain in the autosomal recessive juvenile Parkinson-related E3 ligase parkin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Atypical ubiquitin chains: new molecular signals. 'Protein Modifications: Beyond the Usual Suspects' review series

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Parkin suppresses unfolded protein stress-induced cell death through its E3 ubiquitin-protein ligase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Mitochondrial fission factor Drp1 is essential for embryonic development and synapse formation in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Parkinsonism-inducing neurotoxin, N-methyl-4-phenyl-1,2,3,6 -tetrahydropyridine: uptake of the metabolite N-methyl-4-phenylpyridine by dopamine neurons explains selective toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Parkin protects human dopaminergic neuroblastoma cells against dopamine-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Mitochondrial membrane potential regulates PINK1 import and proteolytic destabilization by PARL

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Regulating mitochondrial outer membrane proteins by ubiquitination and proteasomal degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

The deacetylase HDAC6 regulates aggresome formation and cell viability in response to misfolded protein stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Genetic mutations and functions of PINK1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

PINK1 is recruited to mitochondria with parkin and associates with LC3 in mitophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

PINK1 controls mitochondrial localization of Parkin through direct phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

A role for ubiquitin in selective autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Impaired dopamine release and synaptic plasticity in the striatum of PINK1-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Absence of nigral degeneration in aged parkin/DJ-1/PINK1 triple knockout mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Impairing the mitochondrial fission and fusion balance: a new mechanism of neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Mitochondrial fragmentation in neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

The emerging complexity of protein ubiquitination

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Lewy body-like pathology in long-term embryonic nigral transplants in Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Challenges in Parkinson's disease: restoration of the nigrostriatal dopamine system is not enough

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Evidence of active nerve cell degeneration in the substantia nigra of humans years after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine exposure

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

The effects of oxidative stress on parkin and other E3 ligases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Dopamine covalently modifies and functionally inactivates parkin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

HDAC6 controls autophagosome maturation essential for ubiquitin-selective quality-control autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Disease-causing mutations in parkin impair mitochondrial ubiquitination, aggregation, and HDAC6-dependent mitophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Roles of the mammalian mitochondrial fission and fusion mediators Fis1, Drp1, and Opa1 in apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Autophagy in the Pathogenesis of Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Lewy bodies in grafted neurons in subjects with Parkinson's disease suggest host-to-graft disease propagation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Characterization of PINK1 processing, stability, and subcellular localization

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Structural determinants of PINK1 topology and dual subcellular distribution

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Ubiquitin-proteasome system and mitochondria - reciprocity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Lentiviral vector delivery of parkin prevents dopaminergic degeneration in an alpha-synuclein rat model of Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Loss of parkin or PINK1 function increases Drp1-dependent mitochondrial fragmentation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Genetic mouse models of Parkinson's disease The state of the art.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

A cell biological perspective on mitochondrial dysfunction in Parkinson disease and other neurodegenerative diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Intraneuronal generation of a pyridinium metabolite may cause drug-induced parkinsonism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Emerging roles of mitochondrial proteases in neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Mitochondria in neuroplasticity and neurological disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

The mitochondrial intramembrane protease PARL cleaves human Pink1 to regulate Pink1 trafficking

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Dopamine neurons implanted into people with Parkinson's disease survive without pathology for 14 years

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Axonal mitochondrial transport and potential are correlated

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Autophagy fights disease through cellular self-digestion

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Parkin: a multifaceted ubiquitin ligase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Parkinson's disease mutations in PINK1 result in decreased Complex I activity and deficient synaptic function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Mitochondrial function and morphology are impaired in parkin-mutant fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Parkin is recruited into aggresomes in a stress-specific manner: over-expression of parkin reduces aggresome formation but can be dissociated from parkin's effect on neuronal survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Inter-mitochondrial complementation: Mitochondria-specific system preventing mice from expression of disease phenotypes by mutant mtDNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

p62/SQSTM1 is required for Parkin-induced mitochondrial clustering but not mitophagy; VDAC1 is dispensable for both

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Parkin is recruited selectively to impaired mitochondria and promotes their autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

PINK1 is selectively stabilized on impaired mitochondria to activate Parkin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Inhibition of NADH-linked oxidation in brain mitochondria by 1-methyl-4-phenyl-pyridine, a metabolite of the neurotoxin, 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Genetic etiology of Parkinson disease associated with mutations in the SNCA, PARK2, PINK1, PARK7, and LRRK2 genes: a mutation update

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Missing pieces in the Parkinson's disease puzzle

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Mitochondrial dysfunction and oxidative damage in parkin-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

The PINK1-Parkin pathway is involved in the regulation of mitochondrial remodeling process.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Parkin protects against the toxicity associated with mutant alpha-synuclein: proteasome dysfunction selectively affects catecholaminergic neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

The mitochondrial protease HtrA2 is regulated by Parkinson's disease-associated kinase PINK1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

The PINK1/Parkin pathway regulates mitochondrial morphology

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

The mitochondrial fusion-promoting factor mitofusin is a substrate of the PINK1/parkin pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

PINK1 protects against oxidative stress by phosphorylating mitochondrial chaperone TRAP1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Role of neuronal nitric oxide in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced dopaminergic neurotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Tubular network formation protects mitochondria from autophagosomal degradation during nutrient starvation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Metabolic adaptations through the PGC-1 alpha and SIRT1 pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Parkin protects against mitochondrial toxins and beta-amyloid accumulation in skeletal muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Mitochondrial alterations in PINK1 deficient cells are influenced by calcineurin-dependent dephosphorylation of dynamin-related protein 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Genome-wide association study identifies common variants at four loci as genetic risk factors for Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Metabolic control of mitochondrial biogenesis through the PGC-1 family regulatory network

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Mitochondria in the aetiology and pathogenesis of Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Mitochondria: the next (neurode)generation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Mitochondrial Parkin recruitment is impaired in neurons derived from mutant PINK1 induced pluripotent stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Phosphorylation of parkin by Parkinson disease-linked kinase PINK1 activates parkin E3 ligase function and NF-kappaB signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Functional alteration of PARL contributes to mitochondrial dysregulation in Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Parkin stabilizes PINK1 through direct interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

PARIS (ZNF746) repression of PGC-1α contributes to neurodegeneration in Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Parkinson's Disease: Genetics and Pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Mitochondrial import and enzymatic activity of PINK1 mutants associated to recessive parkinsonism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Genome-wide association study reveals genetic risk underlying Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Positioning mitochondrial plasticity within cellular signaling cascades.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Alpha-synuclein in Lewy bodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Parkin is a component of an SCF-like ubiquitin ligase complex and protects postmitotic neurons from kainate excitotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Impaired mitochondrial transport and Parkin-independent degeneration of respiratory chain-deficient dopamine neurons in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Drosophila HtrA2 is dispensable for apoptosis but acts downstream of PINK1 independently from Parkin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Cytoplasmic localization and proteasomal degradation of N-terminally cleaved form of PINK1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Impaired transcriptional upregulation of Parkin promoter variant under oxidative stress and proteasomal inhibition: clinical association

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Proteasome and p97 mediate mitophagy and degradation of mitofusins induced by Parkin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Quality control of mitochondria: protection against neurodegeneration and ageing

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Parkinson's disease: genetic versus toxin-induced rodent models

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

The role of PTEN-induced kinase 1 in mitochondrial dysfunction and dynamics

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

SLP-2 is required for stress-induced mitochondrial hyperfusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Fission and selective fusion govern mitochondrial segregation and elimination by autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Can overexpression of parkin provide a novel strategy for neuroprotection in Parkinson's disease?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Molecular interaction between parkin and PINK1 in mammalian neuronal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Hereditary early-onset Parkinson's disease caused by mutations in PINK1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Parkin interacts with Ambra1 to induce mitophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Bioenergetics of neurons inhibit the translocation response of Parkin following rapid mitochondrial depolarization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Mitochondrial dynamics in Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Mitochondrial alterations in Parkinson's disease: new clues

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

PINK1-dependent recruitment of Parkin to mitochondria in mitophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Exogenous α-synuclein fibrils induce Lewy body pathology leading to synaptic dysfunction and neuron death

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Stress-induced alterations in parkin solubility promote parkin aggregation and compromise parkin's protective function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Parkin ubiquitinates Drp1 for proteasome-dependent degradation: implication of dysregulated mitochondrial dynamics in Parkinson disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Pink1 Parkinson mutations, the Cdc37/Hsp90 chaperones and Parkin all influence the maturation or subcellular distribution of Pink1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Pink1 forms a multiprotein complex with Miro and Milton, linking Pink1 function to mitochondrial trafficking

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

PGC-1alpha activation as a therapeutic approach in mitochondrial disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Rhomboid-7 and HtrA2/Omi act in a common pathway with the Parkinson's disease factors Pink1 and Parkin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

The parkin protein as a therapeutic target in Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Inactivation of parkin by oxidative stress and C-terminal truncations: a protective role of molecular chaperones

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

The two faces of protein misfolding: gain- and loss-of-function in neurodegenerative diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Relative sensitivity of parkin and other cysteine-containing enzymes to stress-induced solubility alterations

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

PINK1 is necessary for long term survival and mitochondrial function in human dopaminergic neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Dynamics of mitochondrial structure during apoptosis and the enigma of Opa1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Mitochondrial pathology and muscle and dopaminergic neuron degeneration caused by inactivation of Drosophila Pink1 is rescued by Parkin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Pink1 regulates mitochondrial dynamics through interaction with the fission/fusion machinery

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Eaten alive: a history of macroautophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Nitrosative stress linked to sporadic Parkinson's disease: S-nitrosylation of parkin regulates its E3 ubiquitin ligase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Parkin mediates proteasome-dependent protein degradation and rupture of the outer mitochondrial membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Loss-of-function analysis suggests that Omi/HtrA2 is not an essential component of the PINK1/PARKIN pathway in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

The kinase domain of mitochondrial PINK1 faces the cytoplasm

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Silencing of the Pink1 gene expression by conditional RNAi does not induce dopaminergic neuron death in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Drosophila parkin requires PINK1 for mitochondrial translocation and ubiquitinates mitofusin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

Mutations in the mitochondrial GTPase mitofusin 2 cause Charcot-Marie-Tooth neuropathy type 2A

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

NBR1 and p62 as cargo receptors for selective autophagy of ubiquitinated targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0902-3

10.1007/S00401-011-0902-3

21 January 2018

Identifiers

DOI

1 reference

25 August 2017

1 reference

PubMed ID

22057787