(Q37974734)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22233681%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

title

PI3K/AKT, MAPK and AMPK signalling: protein kinases in glucose homeostasis (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22233681%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

0 references

0 references

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22233681%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

2

Brian A Hemmings

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22233681%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

author name string

Simon M Schultze

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22233681%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

Markus Niessen

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22233681%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

publication date

11 January 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22233681%20AND%20SRC:MED&resulttype=core&format=json

Expert Reviews in Molecular Medicine

20 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22233681%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

volume

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22233681%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

page(s)

e1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22233681%20AND%20SRC:MED&resulttype=core&format=json

Efficacy of everolimus in advanced renal cell carcinoma: a double-blind, randomised, placebo-controlled phase III trial

20 January 2020

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Metformin increases fasting plasma peptide tyrosine tyrosine (PYY) in women with polycystic ovarian syndrome (PCOS).

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IRS proteins and the common path to diabetes

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The AMP-activated protein kinase alpha2 catalytic subunit controls whole-body insulin sensitivity

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Identification and characterization of a small molecule AMPK activator that treats key components of type 2 diabetes and the metabolic syndrome

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Severe diabetes, age-dependent loss of adipose tissue, and mild growth deficiency in mice lacking Akt2/PKB beta

21 January 2018

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Use of mouse models in studying type 2 diabetes mellitus

21 January 2018

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Increased insulin sensitivity and hypoglycaemia in mice lacking the p85 alpha subunit of phosphoinositide 3-kinase

21 January 2018

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Adipose tissue selective insulin receptor knockout protects against obesity and obesity-related glucose intolerance

21 January 2018

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Disruption of IRS-2 causes type 2 diabetes in mice

21 January 2018

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Insulin resistance and growth retardation in mice lacking insulin receptor substrate-1.

21 January 2018

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Alternative pathway of insulin signalling in mice with targeted disruption of the IRS-1 gene.

21 January 2018

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A family with severe insulin resistance and diabetes due to a mutation in AKT2.

21 January 2018

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Natural variants of human p85 alpha phosphoinositide 3-kinase in severe insulin resistance: a novel variant with impaired insulin-stimulated lipid kinase activity

21 January 2018

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Gene encoding the catalytic subunit p110beta of human phosphatidylinositol 3-kinase: cloning, genomic structure, and screening for variants in patients with type 2 diabetes

21 January 2018

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Insulin receptor substrate-2 amino acid polymorphisms are not associated with random type 2 diabetes among Caucasians

21 January 2018

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IRS2 variants and syndromes of severe insulin resistance

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The Akt kinases: isoform specificity in metabolism and cancer

21 January 2018

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A common amino acid polymorphism in insulin receptor substrate-1 causes impaired insulin signaling. Evidence from transfection studies

21 January 2018

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New inhibitors of the mammalian target of rapamycin signaling pathway for cancer.

21 January 2018

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A novel T608R missense mutation in insulin receptor substrate-1 identified in a subject with type 2 diabetes impairs metabolic insulin signaling.

21 January 2018

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The nuts and bolts of AGC protein kinases

21 January 2018

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Insulin resistance: interactions between obesity and a common variant of insulin receptor substrate-1.

21 January 2018

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Phosphatase and tensin homolog regulation of islet growth and glucose homeostasis

21 January 2018

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Glycogen synthase kinase 3alpha-specific regulation of murine hepatic glycogen metabolism

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Essential role of protein kinase B gamma (PKB gamma/Akt3) in postnatal brain development but not in glucose homeostasis

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Human diabetes associated with a mutation in the tyrosine kinase domain of the insulin receptor

21 January 2018

1 reference

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The critical role of AKT2 in hepatic steatosis induced by PTEN loss

21 January 2018

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The syndromes of insulin resistance and acanthosis nigricans. Insulin-receptor disorders in man.

21 January 2018

1 reference

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Genetic epidemiology of diabetes

21 January 2018

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Peptides targeting protein kinases: strategies and implications

21 January 2018

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21 January 2018

The two TORCs and Akt.

1 reference

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Structural Basis of Human p70 Ribosomal S6 Kinase-1 Regulation by Activation Loop Phosphorylation

21 January 2018

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https://api.crossref.org/works/10.1017%2FS1462399411002109

Ten years of protein kinase B signalling: a hard Akt to follow

21 January 2018

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https://api.crossref.org/works/10.1017%2FS1462399411002109

Metformin, independent of AMPK, inhibits mTORC1 in a rag GTPase-dependent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411002109

TRB3: a tribbles homolog that inhibits Akt/PKB activation by insulin in liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411002109

Metformin and reduced risk of cancer in diabetic patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411002109

Carboxyl-terminal modulator protein (CTMP), a negative regulator of PKB/Akt and v-Akt at the plasma membrane

21 January 2018

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Metformin and pathologic complete responses to neoadjuvant chemotherapy in diabetic patients with breast cancer

21 January 2018

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Insulin X10 revisited: a super-mitogenic insulin analogue

21 January 2018

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Akt2 is required for hepatic lipid accumulation in models of insulin resistance.

21 January 2018

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A review of modern insulin analogue pharmacokinetic and pharmacodynamic profiles in type 2 diabetes: improvements and limitations

21 January 2018

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Absence of S6K1 protects against age- and diet-induced obesity while enhancing insulin sensitivity

21 January 2018

1 reference

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Divergent regulation of hepatic glucose and lipid metabolism by phosphoinositide 3-kinase via Akt and PKCλ/ζ

21 January 2018

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https://api.crossref.org/works/10.1017%2FS1462399411002109

Molecular and clinical characteristics in 46 families affected with Peutz-Jeghers syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411002109

7 January 2021

Early neonatal death in mice homozygous for a null allele of the insulin receptor gene

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411002109

7 January 2021

Inhibitor kappaB kinase is involved in the paracrine crosstalk between human fat and muscle cells

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411002109

7 January 2021

Effects of adenoviral gene transfer of wild-type, constitutively active, and kinase-defective protein kinase C-lambda on insulin-stimulated glucose transport in L6 myotubes

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411002109

7 January 2021

Metformin prolongs the postprandial fall in plasma ghrelin concentrations in type 2 diabetes

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411002109

7 January 2021

A polymorphism in the AMPKalpha2 subunit gene is associated with insulin resistance and type 2 diabetes in the Japanese population

1 reference

https://api.crossref.org/works/10.1017%2FS1462399411002109

7 January 2021

Hypoglycaemia, liver necrosis and perinatal death in mice lacking all isoforms of phosphoinositide 3-kinase p85 alpha

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7 January 2021

10.1017/S1462399411002109

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22233681%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

1 reference