(Q38007145)

26 August 2017

title

Highlights in antiviral drug research: antivirals at the horizon (English)

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26 August 2017

Erik De Clercq

1

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publication date

2 May 2012

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Medicinal Research Reviews

26 August 2017

published in

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26 August 2017

volume

33

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26 August 2017

issue

6

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26 August 2017

page(s)

1215-1248

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The discovery of antiviral agents: ten different compounds, ten different stories

26 August 2017

cites work

1 reference

Antiviral drug discovery: ten more compounds, and ten more stories (part B).

21 January 2018

1 reference

Another ten stories in antiviral drug discovery (part C): "Old" and "new" antivirals, strategies, and perspectives

21 January 2018

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The next ten stories on antiviral drug discovery (part E): advents, advances, and adventures

21 January 2018

1 reference

Inhibition of the subgenomic hepatitis C virus replicon in huh-7 cells by 2'-deoxy-2'-fluorocytidine.

21 January 2018

1 reference

Design, synthesis, and antiviral activity of 2'-deoxy-2'-fluoro-2'-C-methylcytidine, a potent inhibitor of hepatitis C virus replication

21 January 2018

1 reference

Synthesis and pharmacokinetics of valopicitabine (NM283), an efficient prodrug of the potent anti-HCV agent 2'-C-methylcytidine.

21 January 2018

1 reference

The novel nucleoside analog R1479 (4'-azidocytidine) is a potent inhibitor of NS5B-dependent RNA synthesis and hepatitis C virus replication in cell culture

21 January 2018

1 reference

Design, synthesis, and antiviral properties of 4'-substituted ribonucleosides as inhibitors of hepatitis C virus replication: the discovery of R1479.

21 January 2018

1 reference

2'-deoxy-4'-azido nucleoside analogs are highly potent inhibitors of hepatitis C virus replication despite the lack of 2'-alpha-hydroxyl groups

21 January 2018

1 reference

The design, synthesis, and antiviral activity of monofluoro and difluoro analogues of 4'-azidocytidine against hepatitis C virus replication: the discovery of 4'-azido-2'-deoxy-2'-fluorocytidine and 4'-azido-2'-dideoxy-2',2'-difluorocytidine

21 January 2018

1 reference

2'-deoxy-2'-α-fluoro-2'-β-C-methyl 3',5'-cyclic phosphate nucleotide prodrug analogs as inhibitors of HCV NS5B polymerase: discovery of PSI-352938.

21 January 2018

1 reference

An efficient and diastereoselective synthesis of PSI-6130: a clinically efficacious inhibitor of HCV NS5B polymerase.

21 January 2018

1 reference

Mechanism of Activation of -D-2'-Deoxy-2'-Fluoro-2'-C-Methylcytidine and Inhibition of Hepatitis C Virus NS5B RNA Polymerase

21 January 2018

1 reference

Characterization of the metabolic activation of hepatitis C virus nucleoside inhibitor beta-D-2'-Deoxy-2'-fluoro-2'-C-methylcytidine (PSI-6130) and identification of a novel active 5'-triphosphate species

21 January 2018

1 reference

The Mechanism of Action of -D-2'-Deoxy-2'-Fluoro-2'-C-Methylcytidine Involves a Second Metabolic Pathway Leading to -D-2'-Deoxy-2'-Fluoro-2'-C-Methyluridine 5'-Triphosphate, a Potent Inhibitor of the Hepatitis C Virus RNA-Dependent RNA Polymerase

21 January 2018

1 reference

PSI-7851, a pronucleotide of beta-D-2'-deoxy-2'-fluoro-2'-C-methyluridine monophosphate, is a potent and pan-genotype inhibitor of hepatitis C virus replication

21 January 2018

1 reference

Mechanism of activation of PSI-7851 and its diastereoisomer PSI-7977

21 January 2018

1 reference

Discovery of a β-d-2'-deoxy-2'-α-fluoro-2'-β-C-methyluridine nucleotide prodrug (PSI-7977) for the treatment of hepatitis C virus

21 January 2018

1 reference

Activity and the metabolic activation pathway of the potent and selective hepatitis C virus pronucleotide inhibitor PSI-353661.

21 January 2018

1 reference

Stereoselective synthesis of PSI-352938: a β-D-2'-deoxy-2'-α-fluoro-2'-β-C-methyl-3',5'-cyclic phosphate nucleotide prodrug for the treatment of HCV.

21 January 2018

1 reference

Inhibition of hepatitis C virus replicon RNA synthesis by PSI-352938, a cyclic phosphate prodrug of β-D-2'-deoxy-2'-α-fluoro-2'-β-C-methylguanosine

21 January 2018

1 reference

INX-08189, a phosphoramidate prodrug of 6-O-methyl-2'-C-methyl guanosine, is a potent inhibitor of hepatitis C virus replication with excellent pharmacokinetic and pharmacodynamic properties.

21 January 2018

1 reference

Design, synthesis and evaluation of a novel double pro-drug: INX-08189. A new clinical candidate for hepatitis C virus.

21 January 2018

1 reference

Synthesis and antiviral activity of (Z)- and (E)-2,2-[bis(hydroxymethyl)cyclopropylidene]methylpurines and -pyrimidines: second-generation methylenecyclopropane analogues of nucleosides

21 January 2018

1 reference

In vitro activity and mechanism of action of methylenecyclopropane analogs of nucleosides against herpesvirus replication

21 January 2018

1 reference

Oral activity of a methylenecyclopropane analog, cyclopropavir, in animal models for cytomegalovirus infections

21 January 2018

1 reference

Pivotal role of animal models in the development of new therapies for cytomegalovirus infections

21 January 2018

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In search of effective anti-HHV-6 agents

21 January 2018

1 reference

L-valine ester of cyclopropavir: a new antiviral prodrug.

21 January 2018

1 reference

Cytomegalovirus UL97 mutations affecting cyclopropavir and ganciclovir susceptibility

21 January 2018

1 reference

Stereoselective phosphorylation of cyclopropavir by pUL97 and competitive inhibition by maribavir.

21 January 2018

1 reference

Phosphorylation of antiviral and endogenous nucleotides to di- and triphosphates by guanosine monophosphate kinase.

21 January 2018

1 reference

Phosphonate analogues of cyclopropavir phosphates and their E-isomers. Synthesis and antiviral activity.

21 January 2018

1 reference

Nucleosides with a twist. Can fixed forms of sugar ring pucker influence biological activity in nucleosides and oligonucleotides?

21 January 2018

1 reference

Metabolic pathways of N-methanocarbathymidine, a novel antiviral agent, in native and herpes simplex virus type 1 infected Vero cells

21 January 2018

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Synthesis and biological evaluation of 5-substituted derivatives of the potent antiherpes agent (north)-methanocarbathymine

21 January 2018

1 reference

Dynamics of the antiviral activity of N-methanocarbathymidine against herpes simplex virus type 1 in cell culture

21 January 2018

1 reference

Experimental and structural evidence that herpes 1 kinase and cellular DNA polymerase(s) discriminate on the basis of sugar pucker

21 January 2018

1 reference

Stereospecific synthesis and antiviral properties of different enantiomerically pure carbocyclic 2'-deoxyribonucleoside analogues derived from common chiral pools: (+)-(1R,5S)- and (-)-(1S,5R)-2-oxabicyclo[3.3.0]oct-6-en-3-one

21 January 2018

1 reference

Activity and mechanism of action of N-methanocarbathymidine against herpesvirus and orthopoxvirus infections

21 January 2018

1 reference

Cell line dependency for antiviral activity and in vivo efficacy of N-methanocarbathymidine against orthopoxvirus infections in mice

21 January 2018

1 reference

Efficacy of N-methanocarbathymidine in treating mice infected intranasally with the IHD and WR strains of vaccinia virus

21 January 2018

1 reference

Vaccinia virus lacking the deoxyuridine triphosphatase gene (F2L) replicates well in vitro and in vivo, but is hypersensitive to the antiviral drug (N)-methanocarbathymidine

21 January 2018

1 reference

Potent antiviral activity of north-methanocarbathymidine against Kaposi's sarcoma-associated herpesvirus

21 January 2018

1 reference

A greener enantioselective synthesis of the antiviral agent North-methanocarbathymidine (N-MCT) from 2-deoxy-d-ribose

21 January 2018

1 reference

D-(+)-iso-methanocarbathymidine: a high-affinity substrate for herpes simplex virus 1 thymidine kinase

21 January 2018

1 reference

The history of N-methanocarbathymidine: the investigation of a conformational concept leads to the discovery of a potent and selective nucleoside antiviral agent

21 January 2018

1 reference

Alkoxyalkyl prodrugs of acyclic nucleoside phosphonates enhance oral antiviral activity and reduce toxicity: current state of the art.

21 January 2018

1 reference

Efficacy of CMX001 against herpes simplex virus infections in mice and correlations with drug distribution studies

21 January 2018

1 reference

Oral activity of ether lipid ester prodrugs of cidofovir against experimental human cytomegalovirus infection.

21 January 2018

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Alkoxyalkyl esters of cidofovir and cyclic cidofovir exhibit multiple-log enhancement of antiviral activity against cytomegalovirus and herpesvirus replication in vitro

21 January 2018

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Oral treatment of murine cytomegalovirus infections with ether lipid esters of cidofovir

21 January 2018

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Oral hexadecyloxypropyl-cidofovir therapy in pregnant guinea pigs improves outcome in the congenital model of cytomegalovirus infection

21 January 2018

1 reference

Ether lipid-ester prodrugs of acyclic nucleoside phosphonates: activity against adenovirus replication in vitro

21 January 2018

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Hexadecyloxypropyl-cidofovir, CMX001, prevents adenovirus-induced mortality in a permissive, immunosuppressed animal model

21 January 2018

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Eradication of disseminated adenovirus infection in a pediatric hematopoietic stem cell transplantation recipient using the novel antiviral agent CMX001.

21 January 2018

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Cidofovir inhibits polyomavirus BK replication in human renal tubular cells downstream of viral early gene expression

21 January 2018

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Ether lipid ester derivatives of cidofovir inhibit polyomavirus BK replication in vitro.

21 January 2018

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1-O-hexadecyloxypropyl cidofovir (CMX001) effectively inhibits polyomavirus BK replication in primary human renal tubular epithelial cells

21 January 2018

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Hexadecyloxypropyl-cidofovir (CMX001) suppresses JC virus replication in human fetal brain SVG cell cultures

21 January 2018

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CMX001 (1-O-hexadecyloxypropyl-cidofovir) inhibits polyomavirus JC replication in human brain progenitor-derived astrocytes

21 January 2018

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Treatment of progressive multifocal leukoencephalopathy and idiopathic CD4+ lymphocytopenia

21 January 2018

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Design and development of oral drugs for the prophylaxis and treatment of smallpox infection.

21 January 2018

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Enhanced inhibition of orthopoxvirus replication in vitro by alkoxyalkyl esters of cidofovir and cyclic cidofovir

21 January 2018

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Oral treatment of cowpox and vaccinia virus infections in mice with ether lipid esters of cidofovir.

21 January 2018

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Efficacy of oral active ether lipid analogs of cidofovir in a lethal mousepox model

21 January 2018

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Mousepox in the C57BL/6 strain provides an improved model for evaluating anti-poxvirus therapies

21 January 2018

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Ectromelia virus infections of mice as a model to support the licensure of anti-orthopoxvirus therapeutics

21 January 2018

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Efficacy of therapeutic intervention with an oral ether-lipid analogue of cidofovir (CMX001) in a lethal mousepox model

21 January 2018

1 reference

A mouse model of lethal infection for evaluating prophylactics and therapeutics against Monkeypox virus

21 January 2018

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Poxvirus interleukin-4 expression overcomes inherent resistance and vaccine-induced immunity: pathogenesis, prophylaxis, and antiviral therapy

21 January 2018

1 reference

Efficacy of CMX001 as a post exposure antiviral in New Zealand White rabbits infected with rabbitpox virus, a model for orthopoxvirus infections of humans

21 January 2018

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Efficacy of CMX001 as a prophylactic and presymptomatic antiviral agent in New Zealand white rabbits infected with rabbitpox virus, a model for orthopoxvirus infections of humans

21 January 2018

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Development of CMX001 for the Treatment of Poxvirus Infections

21 January 2018

1 reference

Comparison of the antiviral activities of alkoxyalkyl and alkyl esters of cidofovir against human and murine cytomegalovirus replication in vitro

21 January 2018

1 reference

Synthesis, metabolic stability and antiviral evaluation of various alkoxyalkyl esters of cidofovir and 9-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]adenine

21 January 2018

1 reference

Maporal virus as a surrogate for pathogenic New World hantaviruses and its inhibition by favipiravir

21 January 2018

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In vitro and in vivo activities of anti-influenza virus compound T-705.

21 January 2018

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Mechanism of action of T-705 against influenza virus

21 January 2018

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Intracellular metabolism of favipiravir (T-705) in uninfected and influenza A (H5N1) virus-infected cells

21 January 2018

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T-705 (favipiravir) activity against lethal H5N1 influenza A viruses

21 January 2018

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Efficacy of orally administered T-705 on lethal avian influenza A (H5N1) virus infections in mice

21 January 2018

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In vitro antiviral activity of favipiravir (T-705) against drug-resistant influenza and 2009 A(H1N1) viruses

21 January 2018

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Effects of the combination of favipiravir (T-705) and oseltamivir on influenza A virus infections in mice

21 January 2018

1 reference

T-705 (favipiravir) and related compounds: Novel broad-spectrum inhibitors of RNA viral infections.

21 January 2018

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Activity of T-1106 in a Hamster Model of Yellow Fever Virus Infection

21 January 2018

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Activity of T-705 in a Hamster Model of Yellow Fever Virus Infection in Comparison with That of a Chemically Related Compound, T-1106

21 January 2018

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Efficacy of orally administered T-705 pyrazine analog on lethal West Nile virus infection in rodents

21 January 2018

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Effect of T-705 treatment on western equine encephalitis in a mouse model

21 January 2018

1 reference

In Vitro and In Vivo Activities of T-705 against Arenavirus and Bunyavirus Infections

21 January 2018

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T-705 (favipiravir) inhibition of arenavirus replication in cell culture

21 January 2018

1 reference

Treatment of late stage disease in a model of arenaviral hemorrhagic fever: T-705 efficacy and reduced toxicity suggests an alternative to ribavirin

21 January 2018

1 reference

Efficacy of favipiravir (T-705) and T-1106 pyrazine derivatives in phlebovirus disease models

21 January 2018

1 reference

Lassa fever. Effective therapy with ribavirin

21 January 2018

1 reference

Ribavirin can be mutagenic for arenaviruses.

21 January 2018

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Novel approaches in anti-arenaviral drug development

21 January 2018

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Arenaviruses and hantaviruses: from epidemiology and genomics to antivirals

21 January 2018

1 reference

Development of a new tacaribe arenavirus infection model and its use to explore antiviral activity of a novel aristeromycin analog

21 January 2018

1 reference

Imidazo[2,1-b]thiazole carbohydrate derivatives: Synthesis and antiviral activity against Junin virus, agent of Argentine hemorrhagic fever

21 January 2018

1 reference

Broad-spectrum antiviral activity of small interfering RNA targeting the conserved RNA termini of Lassa virus

21 January 2018

1 reference

Inhibition of different Lassa virus strains by alpha and gamma interferons and comparison with a less pathogenic arenavirus

21 January 2018

1 reference

Antiviral activity of antimicrobial cationic peptides against Junin virus and herpes simplex virus

21 January 2018

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Infectious Lassa virus, but not filoviruses, is restricted by BST-2/tetherin

21 January 2018

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Cap binding and immune evasion revealed by Lassa nucleoprotein structure

21 January 2018

1 reference

Arenavirus reverse genetics: new approaches for the investigation of arenavirus biology and development of antiviral strategies

21 January 2018

1 reference

Pharmacologic inhibition of site 1 protease activity inhibits sterol regulatory element-binding protein processing and reduces lipogenic enzyme gene expression and lipid synthesis in cultured cells and experimental animals

21 January 2018

1 reference

Antiviral activity of a small-molecule inhibitor of arenavirus glycoprotein processing by the cellular site 1 protease

21 January 2018

1 reference

Identification and characterization of potent small molecule inhibitor of hemorrhagic fever New World arenaviruses

21 January 2018

1 reference

Unique small molecule entry inhibitors of hemorrhagic fever arenaviruses

21 January 2018

1 reference

A specific interaction of small molecule entry inhibitors with the envelope glycoprotein complex of the Junín hemorrhagic fever arenavirus

21 January 2018

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pH-induced activation of arenavirus membrane fusion is antagonized by small-molecule inhibitors

21 January 2018

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Identification of a broad-spectrum arenavirus entry inhibitor

21 January 2018

1 reference

Current status of anti-picornavirus therapies

21 January 2018

1 reference

Efficacy and safety of oral pleconaril for treatment of colds due to picornaviruses in adults: results of 2 double-blind, randomized, placebo-controlled trials

21 January 2018

1 reference

Relationship of pleconaril susceptibility and clinical outcomes in treatment of common colds caused by rhinoviruses

21 January 2018

1 reference

Selective inhibitors of picornavirus replication

21 January 2018

1 reference

Enteroviral meningitis: natural history and outcome of pleconaril therapy

21 January 2018

1 reference

New pleconaril and [(biphenyloxy)propyl]isoxazole derivatives with substitutions in the central ring exhibit antiviral activity against pleconaril-resistant coxsackievirus B3

21 January 2018

1 reference

Synthesis and antiviral activity against Coxsackie virus B3 of some novel benzimidazole derivatives

21 January 2018

1 reference

A small interfering RNA targeting coxsackievirus B3 protects permissive HeLa cells from viral challenge

21 January 2018

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Combination of soluble coxsackievirus-adenovirus receptor and anti-coxsackievirus siRNAs exerts synergistic antiviral activity against coxsackievirus B3.

21 January 2018

1 reference

9-Arylpurines as a novel class of enterovirus inhibitors.

21 January 2018

1 reference

Mycophenolate mofetil inhibits the development of Coxsackie B3-virus-induced myocarditis in mice

21 January 2018

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Inhibition of coxsackie B3 virus induced myocarditis in mice by 2-(3,4-dichlorophenoxy)-5-nitrobenzonitrile

21 January 2018

1 reference

The interferon inducer ampligen [poly(I)-poly(C12U)] markedly protects mice against coxsackie B3 virus-induced myocarditis

21 January 2018

1 reference

Towards the design of combination therapy for the treatment of enterovirus infections

21 January 2018

1 reference

The thiazolobenzimidazole TBZE-029 inhibits enterovirus replication by targeting a short region immediately downstream from motif C in the nonstructural protein 2C.

21 January 2018

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Potential use of antiviral agents in polio eradication

21 January 2018

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Picornavirus non-structural proteins as targets for new anti-virals with broad activity

21 January 2018

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Antiviral activity and constituent of Ardisia chinensis benth against coxsackie B3 virus

21 January 2018

1 reference

Antiviral activity and mode of action of caffeoylquinic acids from Schefflera heptaphylla (L.) Frodin

21 January 2018

1 reference

Anti-coxsackie virus B3 norsesquiterpenoids from the roots of Phyllanthus emblica

21 January 2018

1 reference

In vivo and in vitro antiviral activities of calycosin-7-O-beta-D-glucopyranoside against coxsackie virus B3.

21 January 2018

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Antiviral activity of substituted homoisoflavonoids on enteroviruses.

21 January 2018

1 reference

Anti-human cytomegalovirus activity of constituents from Sasa albo-marginata (Kumazasa in Japan).

21 January 2018

1 reference

Increased bioavailability of tricin-amino acid derivatives via a prodrug approach

21 January 2018

1 reference

Genistein treatment of cells inhibits arenavirus infection

21 January 2018

1 reference

Arenavirus entry occurs through a cholesterol-dependent, non-caveolar, clathrin-mediated endocytic mechanism

21 January 2018

1 reference

Genistein, a general kinase inhibitor, as a potential antiviral for arenaviral hemorrhagic fever as described in the Pirital virus-Syrian golden hamster model

21 January 2018

1 reference

Antiviral activity of raoulic acid from Raoulia australis against Picornaviruses

21 January 2018

1 reference

Inhibition of poxvirus growth by Terameprocol, a methylated derivative of nordihydroguaiaretic acid

21 January 2018

1 reference

Nigericin is a potent inhibitor of the early stage of vaccinia virus replication

21 January 2018

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Modulation of glycosylation and transport of viral membrane glycoproteins by a sodium ionophore

21 January 2018

1 reference

Anti-influenza virus activity and structure-activity relationship of aglycoristocetin derivatives with cyclobutenedione carrying hydrophobic chains.

21 January 2018

1 reference

Antiretroviral activity of semisynthetic derivatives of glycopeptide antibiotics

21 January 2018

1 reference

Inhibition of feline (FIPV) and human (SARS) coronavirus by semisynthetic derivatives of glycopeptide antibiotics

21 January 2018

1 reference

Antiviral effect of brassinosteroids against herpes virus and arenaviruses

21 January 2018

1 reference

Antiviral activity of brassinosteroids derivatives against measles virus in cell cultures

21 January 2018

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Antiviral mode of action of a synthetic brassinosteroid against Junin virus replication

21 January 2018

1 reference

Biyouyanagin A, an anti-HIV agent from Hypericum chinense L. var. salicifolium

21 January 2018

1 reference

Design, synthesis, and biological evaluation of a biyouyanagin compound library

21 January 2018

1 reference

Antiviral activity of the MEK-inhibitor U0126 against pandemic H1N1v and highly pathogenic avian influenza virus in vitro and in vivo

21 January 2018

1 reference

Phase I and pharmacodynamic study of the oral MEK inhibitor CI-1040 in patients with advanced malignancies

21 January 2018

1 reference

A phase II study of PD-0325901, an oral MEK inhibitor, in previously treated patients with advanced non-small cell lung cancer

21 January 2018

1 reference

Inhibition of influenza virus-induced NF-kappaB and Raf/MEK/ERK activation can reduce both virus titers and cytokine expression simultaneously in vitro and in vivo

21 January 2018

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MEK inhibition impairs influenza B virus propagation without emergence of resistant variants

21 January 2018

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Influenza virus-induced AP-1-dependent gene expression requires activation of the JNK signaling pathway

21 January 2018

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p38 mitogen-activated protein kinase and c-jun-NH2-terminal kinase regulate RANTES production by influenza virus-infected human bronchial epithelial cells

21 January 2018

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Influenza virus propagation is impaired by inhibition of the Raf/MEK/ERK signalling cascade

21 January 2018

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Modulation of HIV-1 infectivity by MAPK, a virion-associated kinase

21 January 2018

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Inhibition of CD3/CD28-mediated activation of the MEK/ERK signaling pathway represses replication of X4 but not R5 human immunodeficiency virus type 1 in peripheral blood CD4(+) T lymphocytes

21 January 2018

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Coxsackievirus B3 replication is reduced by inhibition of the extracellular signal-regulated kinase (ERK) signaling pathway

21 January 2018

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Suppression of coronavirus replication by inhibition of the MEK signaling pathway

21 January 2018

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Distinct effects of knocking down MEK1 and MEK2 on replication of herpes simplex virus type 2.

21 January 2018

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MEK-specific inhibitor U0126 blocks spread of Borna disease virus in cultured cells

21 January 2018

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The dengue virus envelope protein induced PAI-1 gene expression via MEK/ERK pathways.

21 January 2018

1 reference

PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo

21 January 2018

1 reference

A synthetic inhibitor of the mitogen-activated protein kinase cascade

21 January 2018

1 reference

Visna virus-induced activation of MAPK is required for virus replication and correlates with virus-induced neuropathology

21 January 2018

1 reference

The multi-targeted kinase inhibitor sorafenib inhibits human cytomegalovirus replication.

21 January 2018

1 reference

Platelet-derived growth factor-alpha receptor activation is required for human cytomegalovirus infection

21 January 2018

1 reference

Protein kinase inhibitors of the quinazoline class exert anti-cytomegaloviral activity in vitro and in vivo

21 January 2018

1 reference

A broad-spectrum antiviral targeting entry of enveloped viruses

21 January 2018

1 reference

Rigid amphipathic fusion inhibitors, small molecule antiviral compounds against enveloped viruses

21 January 2018

1 reference

Mechanistic Studies on a Novel Hydrophobic Derivative of Aglycoristocetin with Potent and Broad Activity Against Influenza Viruses

21 January 2018

1 reference

Picornavirus inhibitors: trifluoromethyl substitution provides a global protective effect against hepatic metabolism

21 January 2018

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12 December 2020

A specific inhibitor for tyrosine protein kinase from Pseudomonas

1 reference

12 December 2020

Pleconaril-resistant chronic parechovirus-associated enteropathy in agammaglobulinaemia

1 reference

12 December 2020

Extracellular signal-regulated kinase activity is sustained early during human cytomegalovirus infection

1 reference

12 December 2020

FDA panel rejects common cold treatment

1 reference

12 December 2020

Treatment of potentially life-threatening enterovirus infections with pleconaril

1 reference

12 December 2020

Antiviral flavans from the leaves of Pithecellobium clypearia

1 reference

12 December 2020

Genistein, a specific inhibitor of tyrosine-specific protein kinases

1 reference

12 December 2020

Activity of pleconaril against enteroviruses

1 reference

12 December 2020

Double blind placebo-controlled trial of pleconaril in infants with enterovirus meningitis

1 reference

12 December 2020

Activities of various compounds against murine and primate polyomaviruses

1 reference

12 December 2020

Monensin and nigericin prevent the inhibition of host translation by poliovirus, without affecting p220 cleavage.

1 reference

12 December 2020

Yet another ten stories on antiviral drug discovery (part D): paradigms, paradoxes, and paraductions

1 reference

12 December 2020

Aminopyrrolidineamide inhibitors of site-1 protease

1 reference

12 December 2020

Using biomarkers to stage disease progression in a lethal mousepox model treated with CMX001.

1 reference

12 December 2020

Antiviral triterpenoids from the medicinal plant Schefflera heptaphylla

1 reference

12 December 2020

Identifiers

DOI

10.1002/MED.21256

1 reference

release_lvdjhu2ewrcnvlqaknrcbv7u7a

26 August 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/lvdjhu2ewrcnvlqaknrcbv7u7a

24 November 2022

mapped directly with Wikidata item

1 reference