(Q38076344)

28 August 2017

1 reference

title

Delivery systems and local administration routes for therapeutic siRNA. (English)

1 reference

Lívia Neves Borgheti-Cardoso

28 August 2017

author

object named as

Lívia Neves Borgheti-Cardoso

2

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author name string

Fabiana Testa Moura de Carvalho Vicentini

1

1 reference

28 August 2017

Lívia Vieira Depieri

3

1 reference

28 August 2017

Danielle de Macedo Mano

4

1 reference

28 August 2017

Thais Fedatto Abelha

5

1 reference

28 August 2017

Raquel Petrilli

6

1 reference

28 August 2017

Maria Vitória Lopes Badra Bentley

7

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28 August 2017

publication date

24 January 2013

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28 August 2017

published in

Pharmaceutical Research

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28 August 2017

volume

30

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28 August 2017

issue

4

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28 August 2017

page(s)

915-931

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Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans

28 August 2017

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21 January 2018

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21 January 2018

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Inhalable siRNA: potential as a therapeutic agent in the lungs

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Lipidic systems for in vivo siRNA delivery

21 January 2018

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Knocking down barriers: advances in siRNA delivery

21 January 2018

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Liposome-polyethylenimine complexes for enhanced DNA and siRNA delivery

21 January 2018

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Barrier function of the skin: "la raison d'être" of the epidermis

21 January 2018

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Nanotechnology and the transdermal route: A state of the art review and critical appraisal

21 January 2018

1 reference

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RNAi-mediated suppression of constitutive pulmonary gene expression by small interfering RNA in mice.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11095-013-0971-1

Chitosan-based nanostructures: a delivery platform for ocular therapeutics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-0971-1

RVG peptide tethered bioreducible polyethylenimine for gene delivery to brain

21 January 2018

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Enhanced endosomal escape of siRNA-incorporating hybrid nanoparticles from calcium phosphate and PEG-block charge-conversional polymer for efficient gene knockdown with negligible cytotoxicity

21 January 2018

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Molecular medicine for the brain: silencing of disease genes with RNA interference

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11095-013-0971-1

Development of pH-responsive nanocarriers using trimethylchitosans and methacrylic acid copolymer for siRNA delivery

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11095-013-0971-1

Engineered nanoscaled polyplex gene delivery systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-0971-1

Efficient gene silencing in lungs and liver using imidazole-modified chitosan as a nanocarrier for small interfering RNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-0971-1

Virus-mimetic polymeric micelles for targeted siRNA delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-0971-1

Pulmonary delivery of therapeutic siRNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-0971-1

Gene silencing activity of siRNA polyplexes based on biodegradable polymers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-0971-1

siRNA delivery systems for cancer treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-0971-1

Chitosan-based formulations for delivery of DNA and siRNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-0971-1

Intravaginal gene silencing using biodegradable polymer nanoparticles densely loaded with small-interfering RNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-0971-1

Enhancing the cellular uptake of siRNA duplexes following noncovalent packaging with protein transduction domain peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-0971-1

Translocation of cell penetrating peptide engrafted nanoparticles across skin layers

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-0971-1

Controlled delivery of T-box21 small interfering RNA ameliorates autoimmune alopecia (Alopecia Areata) in a C3H/HeJ mouse model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-0971-1

Delivery of siRNA and other macromolecules into skin and cells using a peptide enhancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-0971-1

A pH-sensitive fusogenic peptide facilitates endosomal escape and greatly enhances the gene silencing of siRNA-containing nanoparticles in vitro and in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-0971-1

Inhibition of respiratory syncytial virus infection with intranasal siRNA nanoparticles targeting the viral NS1 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-0971-1

Neuroprotection by biodegradable PAMAM ester (e-PAM-R)-mediated HMGB1 siRNA delivery in primary cortical cultures and in the postischemic brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-0971-1

Durable protection from Herpes Simplex Virus-2 transmission following intravaginal application of siRNAs targeting both a viral and host gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-0971-1

Flow-through electroporation based on constant voltage for large-volume transfection of cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-0971-1

Electrically assisted ocular gene therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-0971-1

Nanoparticles for retinal gene therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-0971-1

Iontophoresis: a non-invasive ocular drug delivery.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-0971-1

Transdermal iontophoresis as an in-vivo technique for studying microvascular physiology

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-0971-1

Targeting V600EB-Raf and Akt3 using nanoliposomal-small interfering RNA inhibits cutaneous melanocytic lesion development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-0971-1

Enhancement of topical small interfering RNA delivery and expression by low-fluence erbium:YAG laser pretreatment of skin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-0971-1

Electrically assisted delivery of macromolecules into the corneal epithelium

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-0971-1

Single-cell electroporation of adult sensory neurons for gene screening with RNA interference mechanism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-0971-1

Transfer of small interfering RNA by single-cell electroporation in cerebellar cell cultures

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-0971-1

Plasmid DNA and siRNA transfection of intestinal epithelial monolayers by electroporation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-0971-1

Current status and future potential of transdermal drug delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-0971-1

Amelioration of psoriasis by anti-TNF-alpha RNAi in the xenograft transplantation model

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-0971-1

Protein expression of TNF-alpha in psoriatic skin is regulated at a posttranscriptional level by MAPK-activated protein kinase 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-0971-1

Mitogen- and stress-activated protein kinase 1 is activated in lesional psoriatic epidermis and regulates the expression of pro-inflammatory cytokines

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-0971-1

Development of quantitative molecular clinical end points for siRNA clinical trials

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-0971-1

Therapeutic siRNAs for dominant genetic skin disorders including pachyonychia congenita.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-0971-1

First-in-human mutation-targeted siRNA phase Ib trial of an inherited skin disorder.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-0971-1

Alopecia areata: a tissue specific autoimmune disease of the hair follicle

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-0971-1

Topical matrix-based siRNA silences local gene expression in a murine wound model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-0971-1

Melanoma development and progression: a conspiracy between tumor and host

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-0971-1

Acquired and intrinsic BRAF inhibitor resistance in BRAF V600E mutant melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-0971-1

Therapeutic silencing of an endogenous gene by siRNA cream in an arthritis model mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-0971-1

Inhaled drug therapy for treatment of tuberculosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-0971-1

Non-viral siRNA delivery to the lung

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-0971-1

Inhibition of respiratory viruses by nasally administered siRNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-0971-1

Polyethylenimines for RNAi-mediated gene targeting in vivo and siRNA delivery to the lung

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-0971-1

Interaction of bronchoalveolar lavage fluid with polyplexes and lipoplexes: analysing the role of proteins and glycoproteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-0971-1

Inefficient cationic lipid-mediated siRNA and antisense oligonucleotide transfer to airway epithelial cells in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-0971-1

WT1 gene silencing by aerosol delivery of PEI-RNAi complexes inhibits B16-F10 lung metastases growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-0971-1

Suppression of plasminogen activator inhibitor-1 by RNA interference attenuates pulmonary fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-0971-1

Intrapulmonary delivery of XCL1-targeting small interfering RNA in mice chronically infected with Mycobacterium tuberculosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-0971-1

RNA interference of influenza virus production by directly targeting mRNA for degradation and indirectly inhibiting all viral RNA transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-0971-1

A randomized, double-blind, placebo-controlled study of an RNAi-based therapy directed against respiratory syncytial virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-0971-1

RNA interference-mediated silencing of the respiratory syncytial virus nucleocapsid defines a potent antiviral strategy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-0971-1

Evaluation of the safety, tolerability and pharmacokinetics of ALN-RSV01, a novel RNAi antiviral therapeutic directed against respiratory syncytial virus (RSV).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-0971-1

RNA interference therapy in lung transplant patients infected with respiratory syncytial virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-0971-1

Ophthalmic drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-0971-1

Recent developments in ocular gene therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-0971-1

Potential applications for RNAi to probe pathogenesis and develop new treatments for ocular disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-0971-1

Non-viral ocular gene therapy: potential ocular therapeutic avenues.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-0971-1

Ophthalmic drug design based on the metabolic activity of the eye: soft drugs and chemical delivery systems.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-0971-1

Gene delivery to the retina: focus on non-viral approaches

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-0971-1

Toxicogenomics of non-viral drug delivery systems for RNAi: potential impact on siRNA-mediated gene silencing activity and specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-0971-1

Current and future ophthalmic drug delivery systems. A shift to the posterior segment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-0971-1

SiRNA strategy against overexpression of extracellular matrix in diabetic retinopathy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-0971-1

Ocular neovascularization: Implication of endogenous angiogenic inhibitors and potential therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-0971-1

Inhibition of ocular angiogenesis by siRNA targeting vascular endothelial growth factor pathway genes: therapeutic strategy for herpetic stromal keratitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-0971-1

Suppression of ocular neovascularization with siRNA targeting VEGF receptor 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-0971-1

Gene therapy targeting glaucoma: where are we?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-0971-1

Beta-defensin-2 promotes resistance against infection with P. aeruginosa

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-0971-1

Nonviral gene transfection nanoparticles: function and applications in the brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-0971-1

Interfering with the brain: use of RNA interference for understanding the pathophysiology of psychiatric and neurological disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-0971-1

Recent advances in the manipulation of murine gene expression and its utility for the study of human neurological disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-0971-1

RNAi therapeutics for CNS disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-0971-1

RNA interference and nonviral targeted gene therapy of experimental brain cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-0971-1

RNA interference improves motor and neuropathological abnormalities in a Huntington's disease mouse model

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-0971-1

Intrastriatal rAAV-mediated delivery of anti-huntingtin shRNAs induces partial reversal of disease progression in R6/1 Huntington's disease transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-0971-1

Unexpected off-targeting effects of anti-huntingtin ribozymes and siRNA in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-0971-1

A majority of Huntington's disease patients may be treatable by individualized allele-specific RNA interference.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-0971-1

Small interfering RNA targeting the PINK1 induces apoptosis in dopaminergic cells SH-SY5Y.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-0971-1

Silencing mutant SOD1 using RNAi protects against neurodegeneration and extends survival in an ALS model

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-0971-1

Lentiviral-mediated silencing of SOD1 through RNA interference retards disease onset and progression in a mouse model of ALS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-0971-1

Targeting BACE1 with siRNAs ameliorates Alzheimer disease neuropathology in a transgenic model

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-0971-1

Therapeutic application of gene silencing MMP-9 in a middle cerebral artery occlusion-induced focal ischemia rat model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-0971-1

MMP-9 gene silencing by a quantum dot-siRNA nanoplex delivery to maintain the integrity of the blood brain barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-0971-1

Tf-lipoplex-mediated c-Jun silencing improves neuronal survival following excitotoxic damage in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-0971-1

Review article: RNA interference--potential therapeutic applications for the gastroenterologist

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-0971-1

Engineering mucosal RNA interference in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-0971-1

Cholesterol paves the way for topically applied viricides

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-0971-1

An siRNA-based microbicide protects mice from lethal herpes simplex virus 2 infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-0971-1

Vaginal delivery of siRNA using a novel PEGylated lipoplex-entrapped alginate scaffold system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-0971-1

Biological barriers to therapy with antisense and siRNA oligonucleotides

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-0971-1

Cellular delivery of siRNA and antisense oligonucleotides via receptor-mediated endocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-0971-1

Hyaluronic acid-polyethyleneimine conjugate for target specific intracellular delivery of siRNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-0971-1

Target specific intracellular delivery of siRNA/PEI-HA complex by receptor mediated endocytosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-0971-1

A novel tumor-targeted delivery system with hydrophobized hyaluronic acid-spermine conjugates (HHSCs) for efficient receptor-mediated siRNA delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-0971-1

High-density lipoprotein facilitates in vivo delivery of α-tocopherol-conjugated short-interfering RNA to the brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-0971-1

Inhibition of HIV transmission in human cervicovaginal explants and humanized mice using CD4 aptamer-siRNA chimeras

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-013-0971-1

Small interfering RNA (siRNA) delivery into monocyte-derived dendritic cells by electroporation

21 January 2018

1 reference

12 December 2020

Using siRNA in prophylactic and therapeutic regimens against SARS coronavirus in Rhesus macaque

1 reference

12 December 2020

Mitogen- and stress-activated protein kinase 2 and cyclic AMP response element binding protein are activated in lesional psoriatic epidermis

1 reference

12 December 2020

Localized, targeted, and sustained siRNA delivery

1 reference

12 December 2020

RNAi therapeutics: an update on delivery

1 reference

12 December 2020

RNAi tackles a sexually transmitted disease

1 reference

12 December 2020

An eye-opener for RNAi therapeutics

1 reference

12 December 2020

Noninvasive delivery of siRNA into the epidermis by iontophoresis using an atopic dermatitis-like model rat

1 reference

12 December 2020

Small interfering RNA (siRNA) delivery into murine bone marrow-derived dendritic cells by electroporation

1 reference

12 December 2020

Modulation of scratching behavior by silencing an endogenous cyclooxygenase-1 gene in the skin through the administration of siRNA

1 reference

12 December 2020

Drug delivery to the posterior segment of the eye IV: theoretical formulation of a drug delivery system for subconjunctival injection

1 reference

12 December 2020

siRNA relieves chronic neuropathic pain

1 reference

12 December 2020

Liquid crystalline phase nanodispersions enable skin delivery of siRNA

1 reference

12 December 2020

Topical application of cream-emulsified CD86 siRNA ameliorates allergic skin disease by targeting cutaneous dendritic cells

1 reference

12 December 2020

10.1007/S11095-013-0971-1

Identifiers

DOI

1 reference

28 August 2017

0 references

1 reference