(Q38087851)

28 August 2017

title

Regulation of cell migration, invasion and metastasis by IAP proteins and their antagonists (English)

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28 August 2017

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1

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28 August 2017

language of work or name

English

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publication date

11 March 2013

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28 August 2017

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28 August 2017

volume

33

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28 August 2017

issue

6

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28 August 2017

page(s)

671-676

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https://scigraph.springernature.com/pub.10.1038/onc.2013.63

28 August 2017

exact match

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cites work

Targeting IAP proteins for therapeutic intervention in cancer

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.63

IAP proteins: blocking the road to death's door

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.63

Targeting inhibitor of apoptosis proteins for therapeutic intervention.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.63

A conserved XIAP-interaction motif in caspase-9 and Smac/DIABLO regulates caspase activity and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.63

Mechanism of XIAP-mediated inhibition of caspase-9

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.63

Structural basis of caspase-7 inhibition by XIAP

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.63

Structural basis for the inhibition of caspase-3 by XIAP

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.63

Direct inhibition of caspase 3 is dispensable for the anti-apoptotic activity of XIAP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.63

Regulation of apoptosis by XIAP ubiquitin-ligase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.63

IAPs, RINGs and ubiquitylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.63

(Un)expected roles of c-IAPs in apoptotic and NFkappaB signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.63

Ubiquitylation in apoptosis: a post-translational modification at the edge of life and death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.63

Antagonists induce a conformational change in cIAP1 that promotes autoubiquitination

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.63

CARD-mediated autoinhibition of cIAP1's E3 ligase activity suppresses cell proliferation and migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.63

Ubiquitin binding modulates IAP antagonist-stimulated proteasomal degradation of c-IAP1 and c-IAP2(1)

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.63

IAPs contain an evolutionarily conserved ubiquitin-binding domain that regulates NF-kappaB as well as cell survival and oncogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.63

A giant ubiquitin-conjugating enzyme related to IAP apoptosis inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.63

A human IAP-family gene, apollon, expressed in human brain cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.63

Structure of a Survivin-Borealin-INCENP core complex reveals how chromosomal passengers travel together

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.63

Suppression of apoptosis in mammalian cells by NAIP and a related family of IAP genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.63

NLR proteins: integral members of innate immunity and mediators of inflammatory diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.63

Human inhibitor of apoptosis proteins: why XIAP is the black sheep of the family

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.63

Engineering ML-IAP to produce an extraordinarily potent caspase 9 inhibitor: implications for Smac-dependent anti-apoptotic activity of ML-IAP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.63

IkappaB kinase complexes: gateways to NF-kappaB activation and transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.63

cIAP1 and cIAP2 facilitate cancer cell survival by functioning as E3 ligases that promote RIP1 ubiquitination

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.63

c-IAP1 and c-IAP2 are critical mediators of tumor necrosis factor alpha (TNFalpha)-induced NF-kappaB activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.63

Both cIAP1 and cIAP2 regulate TNFalpha-mediated NF-kappaB activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.63

c-IAP1 and UbcH5 promote K11-linked polyubiquitination of RIP1 in TNF signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.63

Recruitment of the linear ubiquitin chain assembly complex stabilizes the TNF-R1 signaling complex and is required for TNF-mediated gene induction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.63

Promiscuous mutations activate the noncanonical NF-kappaB pathway in multiple myeloma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.63

Frequent engagement of the classical and alternative NF-kappaB pathways by diverse genetic abnormalities in multiple myeloma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.63

Rescue of TRAF3-null mice by p100 NF-kappa B deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.63

Classical and/or alternative NF-kappaB pathway activation in multiple myeloma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.63

IAP antagonists induce autoubiquitination of c-IAPs, NF-kappaB activation, and TNFalpha-dependent apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.63

IAP antagonists target cIAP1 to induce TNFalpha-dependent apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.63

TWEAK-FN14 signaling induces lysosomal degradation of a cIAP1-TRAF2 complex to sensitize tumor cells to TNFalpha.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.63

Two distinct signalling cascades target the NF-kappaB regulatory factor c-IAP1 for degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.63

NF-kappaB-inducing kinase regulates the processing of NF-kappaB2 p100

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.63

Activation by IKKalpha of a second, evolutionary conserved, NF-kappa B signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.63

The alternative NF-kappaB pathway from biochemistry to biology: pitfalls and promises for future drug development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.63

Cellular inhibitors of apoptosis are global regulators of NF-κB and MAPK activation by members of the TNF family of receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.63

Activation of NF-kappa B by XIAP, the X chromosome-linked inhibitor of apoptosis, in endothelial cells involves TAK1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.63

XIAP Induces NF-κB Activation via the BIR1/TAB1 Interaction and BIR1 Dimerization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.63

X-linked inhibitor of apoptosis protein functions as a cofactor in transforming growth factor-beta signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.63

IAP suppression of apoptosis involves distinct mechanisms: the TAK1/JNK1 signaling cascade and caspase inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.63

Cellular inhibitors of apoptosis cIAP1 and cIAP2 are required for innate immunity signaling by the pattern recognition receptors NOD1 and NOD2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.63

XIAP mediates NOD signaling via interaction with RIP2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.63

The Ubiquitin Ligase XIAP Recruits LUBAC for NOD2 Signaling in Inflammation and Innate Immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.63

Different modes of ubiquitination of the adaptor TRAF3 selectively activate the expression of type I interferons and proinflammatory cytokines

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.63

Inhibitor of apoptosis proteins limit RIP3 kinase-dependent interleukin-1 activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.63

Virus-triggered ubiquitination of TRAF3/6 by cIAP1/2 is essential for induction of interferon-beta (IFN-beta) and cellular antiviral response

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.63

Modulation of immune signalling by inhibitors of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.63

To fight or die - inhibitor of apoptosis proteins at the crossroad of innate immunity and death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.63

Sept4/ARTS is required for stem cell apoptosis and tumor suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.63

A role for Drosophila IAP1-mediated caspase inhibition in Rac-dependent cell migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.63

Vital functions for lethal caspases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.63

E3 ligase activity of XIAP RING domain is required for XIAP-mediated cancer cell migration, but not for its RhoGDI binding activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.63

RhoGDI SUMOylation at Lys-138 increases its binding activity to Rho GTPase and its inhibiting cancer cell motility.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.63

X-linked inhibitor of apoptosis protein (XIAP) mediates cancer cell motility via Rho GDP dissociation inhibitor (RhoGDI)-dependent regulation of the cytoskeleton

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.63

XIAP is essential for shear stress-enhanced Tyr-576 phosphorylation of FAK.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.63

XIAP reverses various functional activities of FRNK in endothelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.63

X-linked inhibitor of apoptosis protein controls alpha5-integrin-mediated cell adhesion and migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.63

Genomic models of metastatic cancer: functional analysis of death-from-cancer signature genes reveals aneuploid, anoikis-resistant, metastasis-enabling phenotype with altered cell cycle control and activated Polycomb Group (PcG) protein chromatin si

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.63

IAP regulation of metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.63

NF-kappaB and epithelial to mesenchymal transition of cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.63

A smac mimetic reduces TNF related apoptosis inducing ligand (TRAIL)-induced invasion and metastasis of cholangiocarcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.63

X-linked and cellular IAPs modulate the stability of C-RAF kinase and cell motility

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.63

IAPs regulate the plasticity of cell migration by directly targeting Rac1 for degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.63

Role of melanoma inhibitor of apoptosis (ML-IAP) protein, a member of the baculoviral IAP repeat (BIR) domain family, in the regulation of C-RAF kinase and cell migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.63

MAP kinase signalling pathways in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.63

Mammalian Rho GTPases: new insights into their functions from in vivo studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.63

Compensatory proliferation and apoptosis-induced proliferation: a need for clarification.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.63

TRAF2 differentially regulates the canonical and noncanonical pathways of NF-kappaB activation in mature B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.63

Cellular inhibitors of apoptosis proteins cIAP1 and cIAP2 are required for efficient caspase-1 activation by the inflammasome

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.63

An apoptosis-inhibiting baculovirus gene with a zinc finger-like motif

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.63

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/ONC.2013.63

1 reference

Dimensions Publication ID

28 August 2017

1018858524

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1 reference