(Q38107828)

PubMed publication ID

23686238

29 August 2017

title

Interplay between DNA tumor viruses and the host DNA damage response (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6707713&resulttype=core&format=json

12 May 2020

0 references

2

Micah A Luftig

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6707713&resulttype=core&format=json

12 May 2020

author name string

Karyn McFadden

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6707713&resulttype=core&format=json

12 May 2020

publication date

1 January 2013

1 reference

PubMed publication ID

23686238

Current Topics in Microbiology and Immunology

29 August 2017

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6707713&resulttype=core&format=json

12 May 2020

volume

371

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6707713&resulttype=core&format=json

12 May 2020

page(s)

229-257

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6707713&resulttype=core&format=json

The proto-oncogene c-myc is a direct target gene of Epstein-Barr virus nuclear antigen 2.

12 May 2020

cites work

1 reference

12 December 2020

Efficient persistence of extrachromosomal KSHV DNA mediated by latency-associated nuclear antigen

1 reference

12 December 2020

Human papillomavirus is a necessary cause of invasive cervical cancer worldwide

1 reference

12 December 2020

Modulation of the NF-kappa B pathway by virally encoded death effector domains-containing proteins

1 reference

12 December 2020

Epstein-barr virus transformation: involvement of latent membrane protein 1-mediated activation of NF-kappaB.

1 reference

12 December 2020

p53 inhibition by the LANA protein of KSHV protects against cell death

1 reference

12 December 2020

1 reference

12 December 2020

Identification of domains of the HPV11 E1 protein required for DNA replication in vitro

1 reference

12 December 2020

The human papillomavirus type 16 E6 and E7 oncoproteins cooperate to induce mitotic defects and genomic instability by uncoupling centrosome duplication from the cell division cycle

1 reference

12 December 2020

The latent nuclear antigen of Kaposi sarcoma-associated herpesvirus targets the retinoblastoma-E2F pathway and with the oncogene Hras transforms primary rat cells

1 reference

12 December 2020

The expression pattern of Epstein-Barr virus latent genes in vivo is dependent upon the differentiation stage of the infected B cell

1 reference

12 December 2020

Viral interferon regulatory factor 1 of Kaposi's sarcoma-associated herpesvirus binds to p53 and represses p53-dependent transcription and apoptosis.

1 reference

12 December 2020

ATM phosphorylates histone H2AX in response to DNA double-strand breaks

1 reference

12 December 2020

Epstein-Barr virus nuclear antigen 3C putative repression domain mediates coactivation of the LMP1 promoter with EBNA-2.

1 reference

12 December 2020

The human herpes virus 8-encoded viral FLICE inhibitory protein physically associates with and persistently activates the Ikappa B kinase complex

1 reference

12 December 2020

Epstein-Barr virus: exploiting the immune system

1 reference

12 December 2020

Telomeric proteins regulate episomal maintenance of Epstein-Barr virus origin of plasmid replication

1 reference

12 December 2020

Epstein-Barr virus nuclear antigen 3C and prothymosin alpha interact with the p300 transcriptional coactivator at the CH1 and CH3/HAT domains and cooperate in regulation of transcription and histone acetylation.

1 reference

12 December 2020

Adenovirus oncoproteins inactivate the Mre11-Rad50-NBS1 DNA repair complex

1 reference

12 December 2020

Epstein-Barr virus-associated Burkitt lymphomagenesis selects for downregulation of the nuclear antigen EBNA2.

1 reference

12 December 2020

The oncogenic potential of Kaposi's sarcoma-associated herpesvirus cyclin is exposed by p53 loss in vitro and in vivo

1 reference

12 December 2020

The Epstein-Barr virus immediate-early protein BZLF1 regulates p53 function through multiple mechanisms

1 reference

12 December 2020

Repeated phosphopeptide motifs in Claspin mediate the regulated binding of Chk1

1 reference

12 December 2020

DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation

1 reference

12 December 2020

MDC1 is a mediator of the mammalian DNA damage checkpoint

1 reference

12 December 2020

Chk1 and Chk2 kinases in checkpoint control and cancer

1 reference

12 December 2020

Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes

1 reference

12 December 2020

Complex protein-DNA dynamics at the latent origin of DNA replication of Epstein-Barr virus

1 reference

12 December 2020

Phosphorylated claspin interacts with a phosphate-binding site in the kinase domain of Chk1 during ATR-mediated activation

1 reference

12 December 2020

Telomere Repeat Binding Factors TRF1, TRF2, and hRAP1 Modulate Replication of Epstein-Barr Virus OriP

1 reference

12 December 2020

EBNA3C coactivation with EBNA2 requires a SUMO homology domain

1 reference

12 December 2020

The role of p53 in suppression of KSHV cyclin-induced lymphomagenesis

1 reference

12 December 2020

Epstein-Barr virus nuclear antigen 3C regulates cyclin A/p27 complexes and enhances cyclin A-dependent kinase activity

1 reference

12 December 2020

KSHV vFLIP is essential for the survival of infected lymphoma cells

1 reference

12 December 2020

Latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus up-regulates transcription of human telomerase reverse transcriptase promoter through interaction with transcription factor Sp1.

1 reference

12 December 2020

Autophosphorylation of ataxia-telangiectasia mutated is regulated by protein phosphatase 2A.

1 reference

12 December 2020

Human papillomavirus-associated head and neck cancer is a distinct epidemiologic, clinical, and molecular entity

1 reference

12 December 2020

Epstein-Barr virus lytic replication elicits ATM checkpoint signal transduction while providing an S-phase-like cellular environment.

1 reference

12 December 2020

Conserved modes of recruitment of ATM, ATR and DNA-PKcs to sites of DNA damage

1 reference

12 December 2020

Structure of the p53 binding domain of HAUSP/USP7 bound to Epstein-Barr nuclear antigen 1 implications for EBV-mediated immortalization

1 reference

12 December 2020

Epstein-Barr virus EBNA3 proteins bind to the C8/alpha7 subunit of the 20S proteasome and are degraded by 20S proteasomes in vitro, but are very stable in latently infected B cells

1 reference

12 December 2020

A role for the Tip60 histone acetyltransferase in the acetylation and activation of ATM

1 reference

12 December 2020

Epstein-Barr virus latent antigen 3C can mediate the degradation of the retinoblastoma protein through an SCF cellular ubiquitin ligase

1 reference

12 December 2020

Kaposi's sarcoma-associated herpesvirus-encoded latency-associated nuclear antigen induces chromosomal instability through inhibition of p53 function

1 reference

12 December 2020

Inhibition of the ATM/p53 signal transduction pathway by Kaposi's sarcoma-associated herpesvirus interferon regulatory factor 1.

1 reference

12 December 2020

TopBP1 activates the ATR-ATRIP complex

1 reference

12 December 2020

Wip1 Phosphatase Modulates ATM-Dependent Signaling Pathways

1 reference

12 December 2020

ATR-dependent phosphorylation and activation of ATM in response to UV treatment or replication fork stalling

1 reference

12 December 2020

Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints

1 reference

12 December 2020

Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication

1 reference

12 December 2020

Epstein-Barr virus promotes genomic instability in Burkitt's lymphoma

1 reference

12 December 2020

The ATM/ATR signaling effector Chk2 is targeted by Epstein-Barr virus nuclear antigen 3C to release the G2/M cell cycle block

1 reference

12 December 2020

ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage

1 reference

12 December 2020

Viral oncogene-induced DNA damage response is activated in Kaposi sarcoma tumorigenesis

1 reference

12 December 2020

RNF8 ubiquitylates histones at DNA double-strand breaks and promotes assembly of repair proteins

1 reference

12 December 2020

RNF8 transduces the DNA-damage signal via histone ubiquitylation and checkpoint protein assembly

1 reference

12 December 2020

Gamma-herpesvirus kinase actively initiates a DNA damage response by inducing phosphorylation of H2AX to foster viral replication

1 reference

12 December 2020

Orchestration of the DNA-damage response by the RNF8 ubiquitin ligase

1 reference

12 December 2020

A role for MRE11, NBS1, and recombination junctions in replication and stable maintenance of EBV episomes

1 reference

12 December 2020

Human papillomaviruses activate caspases upon epithelial differentiation to induce viral genome amplification

1 reference

12 December 2020

DNA damage signalling guards against activated oncogenes and tumour progression

1 reference

12 December 2020

Epstein-Barr virus nuclear antigen 3C interacts with and enhances the stability of the c-Myc oncoprotein

1 reference

12 December 2020

Epstein-Barr virus latent membrane protein 1 represses DNA repair through the PI3K/Akt/FOXO3a pathway in human epithelial cells

1 reference

12 December 2020

How shelterin protects mammalian telomeres

1 reference

12 December 2020

Involvement of human ORC and TRF2 in pre-replication complex assembly at telomeres.

1 reference

12 December 2020

RNA-dependent recruitment of the origin recognition complex

1 reference

12 December 2020

Efficiency of transformation of lymphocytes by Epstein-Barr virus

1 reference

12 December 2020

Epstein-Barr virus episome stability is coupled to a delay in replication timing

1 reference

12 December 2020

The Epstein-Barr virus nuclear antigen-1 promotes genomic instability via induction of reactive oxygen species.

1 reference

12 December 2020

RNF168 binds and amplifies ubiquitin conjugates on damaged chromosomes to allow accumulation of repair proteins

1 reference

12 December 2020

Epstein-Barr virus nuclear antigen 3C augments Mdm2-mediated p53 ubiquitination and degradation by deubiquitinating Mdm2.

1 reference

12 December 2020

Oncogenic HPV infection interrupts the expression of tumor-suppressive miR-34a through viral oncoprotein E6

1 reference

12 December 2020

Autophagy mediates the mitotic senescence transition

1 reference

12 December 2020

The shelterin protein TRF2 inhibits Chk2 activity at telomeres in the absence of DNA damage.

1 reference

12 December 2020

Mechanism of genomic instability in cells infected with the high-risk human papillomaviruses

1 reference

12 December 2020

Frequent inactivation of A20 in B-cell lymphomas

1 reference

12 December 2020

Taking the time to make important decisions: the checkpoint effector kinases Chk1 and Chk2 and the DNA damage response

1 reference

12 December 2020

EBV and genomic instability--a new look at the role of the virus in the pathogenesis of Burkitt's lymphoma.

1 reference

12 December 2020

Three Epstein-Barr virus latency proteins independently promote genomic instability by inducing DNA damage, inhibiting DNA repair and inactivating cell cycle checkpoints

1 reference

12 December 2020

Clonal transformation of adult human leukocytes by Epstein-Barr virus

1 reference

12 December 2020

Human papillomaviruses activate the ATM DNA damage pathway for viral genome amplification upon differentiation

1 reference

12 December 2020

FLIP-mediated autophagy regulation in cell death control

1 reference

12 December 2020

Chromosomal rearrangements after ex vivo Epstein–Barr virus (EBV) infection of human B cells

1 reference

12 December 2020

Autophosphorylation at serine 1981 stabilizes ATM at DNA damage sites

1 reference

12 December 2020

A deneddylase encoded by Epstein-Barr virus promotes viral DNA replication by regulating the activity of cullin-RING ligases

1 reference

12 December 2020

Regulation of Epstein-Barr virus origin of plasmid replication (OriP) by the S-phase checkpoint kinase Chk2.

1 reference

12 December 2020

RAD18-dependent recruitment of SNM1A to DNA repair complexes by a ubiquitin-binding zinc finger

1 reference

12 December 2020

Epigenetic repression of p16(INK4A) by latent Epstein-Barr virus requires the interaction of EBNA3A and EBNA3C with CtBP.

1 reference

12 December 2020

Multiple roles of ATM in monitoring and maintaining DNA integrity

1 reference

12 December 2020

Human papillomavirus oncoproteins: pathways to transformation

1 reference

12 December 2020

Genomes in Conflict: Maintaining Genome Integrity During Virus Infection

1 reference

12 December 2020

Kaposi's sarcoma and its associated herpesvirus

1 reference

12 December 2020

ATM activation by oxidative stress

1 reference

12 December 2020

The ATM-Chk2 and ATR-Chk1 pathways in DNA damage signaling and cancer

1 reference

12 December 2020

DNA-SCARS: distinct nuclear structures that sustain damage-induced senescence growth arrest and inflammatory cytokine secretion

1 reference

12 December 2020

An ATM/Chk2-mediated DNA damage-responsive signaling pathway suppresses Epstein-Barr virus transformation of primary human B cells

1 reference

12 December 2020

EBNA3C attenuates the function of p53 through interaction with inhibitor of growth family proteins 4 and 5

1 reference

12 December 2020

Noise cancellation: viral fine tuning of the cellular environment for its own genome replication.

1 reference

12 December 2020

Epstein-Barr virus nuclear antigens 3C and 3A maintain lymphoblastoid cell growth by repressing p16INK4A and p14ARF expression

1 reference

12 December 2020

Human papillomavirus (HPV) E7 induces prolonged G2 following S phase reentry in differentiated human keratinocytes

1 reference

12 December 2020

The Epstein-Barr virus nuclear antigen-1 promotes telomere dysfunction via induction of oxidative stress

1 reference

12 December 2020

Nucleotide deficiency promotes genomic instability in early stages of cancer development

1 reference

12 December 2020

ATR signalling: more than meeting at the fork

1 reference

12 December 2020

Nuclear accumulation of the papillomavirus E1 helicase blocks S-phase progression and triggers an ATM-dependent DNA damage response

1 reference

12 December 2020

The papillomavirus E1 helicase activates a cellular DNA damage response in viral replication foci

1 reference

12 December 2020

At a crossroads: human DNA tumor viruses and the host DNA damage response.

1 reference

12 December 2020

Conserved herpesvirus kinases target the DNA damage response pathway and TIP60 histone acetyltransferase to promote virus replication.

1 reference

12 December 2020

The DNA damage response in viral-induced cellular transformation

1 reference

12 December 2020

Hitchhiking on host chromatin: how papillomaviruses persist.

1 reference

12 December 2020

Subversion of autophagy by Kaposi's sarcoma-associated herpesvirus impairs oncogene-induced senescence

1 reference

12 December 2020

Telomeric DNA damage is irreparable and causes persistent DNA-damage-response activation

1 reference

12 December 2020

The Epstein-Barr virus (EBV)-induced tumor suppressor microRNA MiR-34a is growth promoting in EBV-infected B cells

1 reference

12 December 2020

The viral interferon regulatory factors of KSHV: immunosuppressors or oncogenes?

1 reference

12 December 2020

Oncogene-induced telomere dysfunction enforces cellular senescence in human cancer precursor lesions

1 reference

12 December 2020

Epstein-Barr virus BPLF1 deubiquitinates PCNA and attenuates polymerase η recruitment to DNA damage sites

1 reference

12 December 2020

Human papillomaviruses recruit cellular DNA repair and homologous recombination factors to viral replication centers

1 reference

12 December 2020

Analysis of Epstein-Barr virus-regulated host gene expression changes through primary B-cell outgrowth reveals delayed kinetics of latent membrane protein 1-mediated NF-κB activation

1 reference

12 December 2020

The cellular ataxia telangiectasia-mutated kinase promotes epstein-barr virus lytic reactivation in response to multiple different types of lytic reactivation-inducing stimuli

1 reference

12 December 2020

Engagement of the ATR-dependent DNA damage response at the human papillomavirus 18 replication centers during the initial amplification

1 reference

12 December 2020

Replication of Epstein-Barr viral DNA.

1 reference

12 December 2020

The E6 and E7 genes of the human papillomavirus type 16 together are necessary and sufficient for transformation of primary human keratinocytes

1 reference

12 December 2020

The human papilloma virus-16 E7 oncoprotein is able to bind to the retinoblastoma gene product

1 reference

12 December 2020

Complex formation of human papillomavirus E7 proteins with the retinoblastoma tumor suppressor gene product

1 reference

12 December 2020

Stable replication of plasmids derived from Epstein-Barr virus in various mammalian cells

1 reference

12 December 2020

Structure and transcription of human papillomavirus sequences in cervical carcinoma cells

1 reference

12 December 2020

Sequence-specific DNA binding of the Epstein-Barr virus nuclear antigen (EBNA-1) to clustered sites in the plasmid maintenance region

1 reference

12 December 2020

Bovine papillomavirus E2 trans-activating gene product binds to specific sites in papillomavirus DNA

1 reference

12 December 2020

Integral membrane protein 2 of Epstein-Barr virus regulates reactivation from latency through dominant negative effects on protein-tyrosine kinases

1 reference

12 December 2020

Identification of herpesvirus-like DNA sequences in AIDS-associated Kaposi's sarcoma

1 reference

12 December 2020

EBNA-2 and EBNA-LP cooperate to cause G0 to G1 transition during immortalization of resting human B lymphocytes by Epstein-Barr virus.

1 reference

12 December 2020

Functional and physical interaction between p53 and BZLF1: implications for Epstein-Barr virus latency

1 reference

12 December 2020

The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53

1 reference

12 December 2020

EBNA-2 and EBNA-3C extensively and mutually exclusively associate with RBPJkappa in Epstein-Barr virus-transformed B lymphocytes

1 reference

12 December 2020

A conserved domain of the Epstein-Barr virus nuclear antigens 3A and 3C binds to a discrete domain of Jkappa

1 reference

12 December 2020

10.1007/978-3-642-37765-5_9

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6707713&resulttype=core&format=json

12 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6707713&resulttype=core&format=json

12 May 2020

PubMed publication ID

23686238

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6707713&resulttype=core&format=json