(Q38193549)

30 August 2017

1 reference

title

Regulated intramembrane proteolysis of the TGFβ type I receptor conveys oncogenic signals (English)

1 reference

30 August 2017

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24597658%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

Marene Landström

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24597658%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

author name string

Anders Wallenius

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24597658%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

language of work or name

English

0 references

publication date

5 March 2014

1 reference

30 August 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24597658%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

volume

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24597658%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

issue

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24597658%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

page(s)

1853-1861

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24597658%20AND%20SRC:MED&resulttype=core&format=json

TGFβ signalling in context

8 June 2020

cites work

1 reference

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Non-Smad signaling pathways

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Tgf-beta superfamily signaling in embryonic development and homeostasis

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Signaling via hetero-oligomeric complexes of type I and type II serine/threonine kinase receptors

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Cooperative assembly of TGF-beta superfamily signaling complexes is mediated by two disparate mechanisms and distinct modes of receptor binding

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Mechanism of activation of the TGF-beta receptor

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Identification of a member of the MAPKKK family as a potential mediator of TGF-beta signal transduction

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TGF-beta signaling: positive and negative effects on tumorigenesis

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Non-Smad pathways in TGF-beta signaling

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The type I TGF-beta receptor engages TRAF6 to activate TAK1 in a receptor kinase-independent manner

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Phosphatidylinositol 3-kinase function is required for transforming growth factor beta-mediated epithelial to mesenchymal transition and cell migration.

21 January 2018

1 reference

Signaling interplay between transforming growth factor-β receptor and PI3K/AKT pathways in cancer

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Polyubiquitination of transforming growth factor β (TGFβ)-associated kinase 1 mediates nuclear factor-κB activation in response to different inflammatory stimuli.

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1 reference

TRAF6 mediates Smad-independent activation of JNK and p38 by TGF-beta

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A presenilin-1-dependent gamma-secretase-like protease mediates release of Notch intracellular domain

21 January 2018

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Molecular and cellular mechanisms of ectodomain shedding

21 January 2018

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Moonlighting activity of presenilin in plants is independent of gamma-secretase and evolutionarily conserved

21 January 2018

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Dictyostelium possesses highly diverged presenilin/gamma-secretase that regulates growth and cell-fate specification and can accurately process human APP: a system for functional studies of the presenilin/gamma-secretase complex

21 January 2018

1 reference

Regulated intramembrane proteolysis: a control mechanism conserved from bacteria to humans

21 January 2018

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A CBP binding transcriptional repressor produced by the PS1/epsilon-cleavage of N-cadherin is inhibited by PS1 FAD mutations

21 January 2018

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ADAM10 cleavage of N-cadherin and regulation of cell-cell adhesion and beta-catenin nuclear signalling

21 January 2018

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Regulated intracellular ligand transport and proteolysis control EGF signal activation in Drosophila

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Drosophila rhomboid-1 defines a family of putative intramembrane serine proteases

21 January 2018

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21 January 2018

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21 January 2018

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Signaling from the secretory granule to the nucleus

21 January 2018

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The role of protease activity in ErbB biology

21 January 2018

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Receptor tyrosine kinases in the nucleus

21 January 2018

1 reference

Presenilins: members of the gamma-secretase quartets, but part-time soloists too.

21 January 2018

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Presenilin function and gamma-secretase activity

21 January 2018

1 reference

Novel research horizons for presenilins and γ-secretases in cell biology and disease

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Intramembrane proteolysis by presenilin and presenilin-like proteases

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Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease

21 January 2018

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Presenilin-dependent regulated intramembrane proteolysis and gamma-secretase activity

21 January 2018

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gamma-Secretase, Notch, Abeta and Alzheimer's disease: where do the presenilins fit in?

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Got RIP? Presenilin-dependent intramembrane proteolysis in growth factor receptor signaling

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Intramembrane proteolysis in regulated protein trafficking

21 January 2018

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Endoproteolysis of presenilin 1 and accumulation of processed derivatives in vivo

21 January 2018

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21 January 2018

1 reference

TACE-mediated ectodomain shedding of the type I TGF-beta receptor downregulates TGF-beta signaling

21 January 2018

1 reference

TRAF6 stimulates the tumor-promoting effects of TGFβ type I receptor through polyubiquitination and activation of presenilin 1.

21 January 2018

1 reference

Clathrin- and non-clathrin-mediated endocytic regulation of cell signalling

21 January 2018

1 reference

Distinct endocytic pathways regulate TGF-β receptor signalling and turnover

21 January 2018

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Endocytic regulation of TGF-beta signaling

21 January 2018

1 reference

TGF beta receptor internalization into EEA1-enriched early endosomes: role in signaling to Smad2

21 January 2018

1 reference

Post-translational regulation of TGF-β receptor and Smad signaling.

21 January 2018

1 reference

The TAK1-TRAF6 signalling pathway

21 January 2018

1 reference

TACE activation by MAPK-mediated regulation of cell surface dimerization and TIMP3 association.

21 January 2018

1 reference

Signal transduction and endocytosis: close encounters of many kinds

21 January 2018

1 reference

Nuclear signaling by receptor tyrosine kinases: the first robin of spring

21 January 2018

1 reference

Trafficking of receptor tyrosine kinases to the nucleus

21 January 2018

1 reference

The ErbB/HER family of protein-tyrosine kinases and cancer

21 January 2018

1 reference

Beyond TGFβ: roles of other TGFβ superfamily members in cancer

21 January 2018

1 reference

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21 January 2018

1 reference

RanBPM interacts with TβRI, TRAF6 and curbs TGF induced nuclear accumulation of TβRI.

21 January 2018

1 reference

Protein inhibitor of activated STAT3 (PIAS3) protein promotes SUMOylation and nuclear sequestration of the intracellular domain of ErbB4 protein

21 January 2018

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21 January 2018

1 reference

Activation of Notch signaling is required for cholangiocarcinoma progression and is enhanced by inactivation of p53 in vivo

21 January 2018

1 reference

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21 January 2018

1 reference

Notch and cancer: a double-edged sword

21 January 2018

1 reference

Nuclear translocation of type I transforming growth factor β receptor confers a novel function in RNA processing

21 January 2018

1 reference

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21 January 2018

1 reference

Targeting the Transforming Growth Factor-β Signaling in Cancer Therapy

21 January 2018

1 reference

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21 January 2018

1 reference

gamma -Secretase cleavage and nuclear localization of ErbB-4 receptor tyrosine kinase

21 January 2018

1 reference

Heregulin-dependent Trafficking and Cleavage of ErbB-4

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.2217/FON.14.45

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24597658%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

1 reference