(Q38202550)

30 August 2017

title

Discoidin domain receptors: a proteomic portrait (English)

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30 August 2017

3

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30 August 2017

Leo K Iwai

1

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30 August 2017

Maciej T Luczynski

series ordinal

2

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30 August 2017

publication date

5 April 2014

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Cellular and Molecular Life Sciences

30 August 2017

published in

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30 August 2017

volume

71

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30 August 2017

issue

17

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30 August 2017

page(s)

3269-3279

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Discoidin domain receptors: unique receptor tyrosine kinases in collagen-mediated signaling

30 August 2017

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The discoidin domain receptor DDR2 is a receptor for type X collagen

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An orphan receptor tyrosine kinase family whose members serve as nonintegrin collagen receptors

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The discoidin domain receptor tyrosine kinases are activated by collagen

21 January 2018

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Oncogenic kinase signalling

21 January 2018

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Kinase drug discovery--what's next in the field?

21 January 2018

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Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib

21 January 2018

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ALK inhibition for non-small cell lung cancer: from discovery to therapy in record time

21 January 2018

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Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia

21 January 2018

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Consistent and selective expression of the discoidin domain receptor-1 tyrosine kinase in human brain tumors

21 January 2018

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Identification of expressed genes characterizing long-term survival in malignant glioma patients

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-014-1616-1

Mutations in the DDR2 kinase gene identify a novel therapeutic target in squamous cell lung cancer

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-014-1616-1

Increased expression of discoidin domain receptor 2 (DDR2): a novel independent prognostic marker of worse outcome in breast cancer patients.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-014-1616-1

Expression and mutation analysis of the discoidin domain receptors 1 and 2 in non-small cell lung carcinoma

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-014-1616-1

Epidermal growth factor receptor activity determines response of colorectal cancer cells to gefitinib alone and in combination with chemotherapy

21 January 2018

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Epithelial to mesenchymal transition is a determinant of sensitivity of non-small-cell lung carcinoma cell lines and xenografts to epidermal growth factor receptor inhibition

21 January 2018

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Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer

21 January 2018

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Higher expression of EphA2 and ephrin-A1 is related to favorable clinicopathological features in pathological stage I non-small cell lung carcinoma.

21 January 2018

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The tumor microenvironment: a critical determinant of neoplastic evolution

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-014-1616-1

Survey of tyrosine kinase signaling reveals ROS kinase fusions in human cholangiocarcinoma

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-014-1616-1

Phosphoproteomics identifies driver tyrosine kinases in sarcoma cell lines and tumors

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-014-1616-1

The human rhabdomyosarcoma cell line A204 lays down a highly insoluble matrix composed mainly of alpha 1 type-XI and alpha 2 type-V collagen chains

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-014-1616-1

Receptor tyrosine kinase coactivation networks in cancer

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-014-1616-1

Phosphoproteomic studies of receptor tyrosine kinases: future perspectives

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-014-1616-1

Molecular characterization of EGFR and EGFRvIII signaling networks in human glioblastoma tumor xenografts

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-014-1616-1

Phosphoproteomic analysis identifies insulin enhancement of discoidin domain receptor 2 phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1616-1

The receptor AXL diversifies EGFR signaling and limits the response to EGFR-targeted inhibitors in triple-negative breast cancer cells

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-014-1616-1

Solution conformations and dynamics of ABL kinase-inhibitor complexes determined by NMR substantiate the different binding modes of imatinib/nilotinib and dasatinib

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1616-1

Quantitative chemical proteomics reveals mechanisms of action of clinical ABL kinase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1616-1

Characterization of AMN107, a selective inhibitor of native and mutant Bcr-Abl.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1616-1

Chemical proteomic profiles of the BCR-ABL inhibitors imatinib, nilotinib, and dasatinib reveal novel kinase and nonkinase targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1616-1

Effect of the tyrosine kinase inhibitor STI571 in a patient with a metastatic gastrointestinal stromal tumor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1616-1

Efficacy and safety of imatinib mesylate in advanced gastrointestinal stromal tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1616-1

Kinase mutations and imatinib response in patients with metastatic gastrointestinal stromal tumor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1616-1

Inhibition of collagen-induced discoidin domain receptor 1 and 2 activation by imatinib, nilotinib and dasatinib

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1616-1

HSP90 at the hub of protein homeostasis: emerging mechanistic insights

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-014-1616-1

Quantitative proteomics reveals that Hsp90 inhibition preferentially targets kinases and the DNA damage response

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-014-1616-1

Systematic identification of the HSP90 candidate regulated proteome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1616-1

Hsp90 inhibition differentially destabilises MAP kinase and TGF-beta signalling components in cancer cells revealed by kinase-targeted chemoproteomics

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-014-1616-1

A chemical and phosphoproteomic characterization of dasatinib action in lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1616-1

Clinical resistance to STI-571 cancer therapy caused by BCR-ABL gene mutation or amplification

21 January 2018

1 reference

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Acquired resistance of lung adenocarcinomas to gefitinib or erlotinib is associated with a second mutation in the EGFR kinase domain

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-014-1616-1

Acquired resistance to dasatinib in lung cancer cell lines conferred by DDR2 gatekeeper mutation and NF1 loss

21 January 2018

1 reference

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ATP-competitive inhibitors block protein kinase recruitment to the Hsp90-Cdc37 system

21 January 2018

1 reference

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Actinomycin D identified as an inhibitor of discoidin domain receptor 2 interaction with collagen through an insect cell based screening of a drug compound library

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1616-1

Discoipyrroles A-D: isolation, structure determination, and synthesis of potent migration inhibitors from Bacillus hunanensis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1616-1

Using functional signature ontology (FUSION) to identify mechanisms of action for natural products

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1616-1

Discovery and optimization of 3-(2-(Pyrazolo[1,5-a]pyrimidin-6-yl)ethynyl)benzamides as novel selective and orally bioavailable discoidin domain receptor 1 (DDR1) inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1616-1

Discovery of a Potent and Selective DDR1 Receptor Tyrosine Kinase Inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1616-1

Dynamic reprogramming of the kinome in response to targeted MEK inhibition in triple-negative breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1616-1

MYC on the path to cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1616-1

Pinpointing phosphotyrosine-dependent interactions downstream of the collagen receptor DDR1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1616-1

A discoidin domain receptor 1/SHP-2 signaling complex inhibits alpha2beta1-integrin-mediated signal transducers and activators of transcription 1/3 activation and cell migration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1616-1

Proteomic, functional and motif-based analysis of C-terminal Src kinase-interacting proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1616-1

Transcriptional upregulation of DDR2 by ATF4 facilitates osteoblastic differentiation through p38 MAPK-mediated Runx2 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1616-1

An essential role of discoidin domain receptor 2 (DDR2) in osteoblast differentiation and chondrocyte maturation via modulation of Runx2 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1616-1

Phosphotyrosine mediated protein interactions of the discoidin domain receptor 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1616-1

DDR1 receptor tyrosine kinase promotes prosurvival pathway through Notch1 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1616-1

The collagen receptor DDR1 regulates cell spreading and motility by associating with myosin IIA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1616-1

Collagen I-mediated up-regulation of N-cadherin requires cooperative signals from integrins and discoidin domain receptor 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1616-1

Collective cell migration requires suppression of actomyosin at cell-cell contacts mediated by DDR1 and the cell polarity regulators Par3 and Par6.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1616-1

Phosphorylation of DARPP-32 regulates breast cancer cell migration downstream of the receptor tyrosine kinase DDR1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1616-1

KIBRA interacts with discoidin domain receptor 1 to modulate collagen-induced signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1616-1

Discoidin domain receptor 1 receptor tyrosine kinase induces cyclooxygenase-2 and promotes chemoresistance through nuclear factor-kappaB pathway activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1616-1

Phosphoproteomics of collagen receptor networks reveals SHP-2 phosphorylation downstream of wild-type DDR2 and its lung cancer mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1616-1

Autophosphorylation of FGFR1 kinase is mediated by a sequential and precisely ordered reaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1616-1

Tyrosine 740 phosphorylation of discoidin domain receptor 2 by Src stimulates intramolecular autophosphorylation and Shc signaling complex formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1616-1

Discoidin domain receptor 2 interacts with Src and Shc following its activation by type I collagen

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1616-1

Discoidin domain receptor 2 is associated with the increased expression of matrix metalloproteinase-13 in synovial fibroblasts of rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1616-1

A transmembrane leucine zipper is required for activation of the dimeric receptor tyrosine kinase DDR1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1616-1

Mapping of DDR1 distribution and oligomerization on the cell surface by FRET microscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1616-1

The pathobiology of collagens in glioma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1616-1

Shedding of discoidin domain receptor 1 by membrane-type matrix metalloproteinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1616-1

Crystallographic insight into collagen recognition by discoidin domain receptor 2

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1616-1

Discoidin domain receptors promote α1β1- and α2β1-integrin mediated cell adhesion to collagen by enhancing integrin activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1616-1

Temporal regulation of EGF signalling networks by the scaffold protein Shc1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1616-1

Biosynthesis of type V procollagen by A204, a human rhabdomyosarcoma cell line

21 January 2018

1 reference

12 December 2020

Functional analysis of discoidin domain receptor 1: effect of adhesion on DDR1 phosphorylation

1 reference

12 December 2020

Aberrant epidermal growth factor receptor signaling and enhanced sensitivity to EGFR inhibitors in lung cancer.

1 reference

12 December 2020

The precise sequence of FGF receptor autophosphorylation is kinetically driven and is disrupted by oncogenic mutations

1 reference

12 December 2020

EGFR and MET receptor tyrosine kinase-altered microRNA expression induces tumorigenesis and gefitinib resistance in lung cancers

1 reference

12 December 2020

Glycosylation at Asn211 regulates the activation state of the discoidin domain receptor 1 (DDR1).

1 reference

12 December 2020

Expression and signaling activity of Wnt-5a/discoidin domain receptor-1 and Syk plays distinct but decisive roles in breast cancer patient survival.

1 reference

12 December 2020

DDR1 signaling is essential to sustain Stat5 function during lactogenesis

1 reference

12 December 2020

10.1007/S00018-014-1616-1

Identifiers

DOI

1 reference

30 August 2017

1 reference