(Q38289421)

1 September 2017

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title

Nuclear bile acid signaling through the farnesoid X receptor (English)

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1 September 2017

3

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1 September 2017

Claire Mazuy

1

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1 September 2017

Audrey Helleboid

series ordinal

2

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1 September 2017

Philippe Lefebvre

series ordinal

4

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1 September 2017

publication date

16 December 2014

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Cellular and Molecular Life Sciences

1 September 2017

published in

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1 September 2017

volume

72

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1 September 2017

issue

9

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1 September 2017

page(s)

1631-1650

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https://scigraph.springernature.com/pub.10.1007/s00018-014-1805-y

1 September 2017

exact match

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cites work

Functional specificities of Brm and Brg-1 Swi/Snf ATPases in the feedback regulation of hepatic bile acid biosynthesis

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12 December 2020

New developments in glucuronidation research: report of a workshop on "glucuronidation, its role in health and disease"

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12 December 2020

Activation of the farnesoid X receptor provides protection against acetaminophen-induced hepatic toxicity

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12 December 2020

The interaction between bacteria and bile.

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12 December 2020

Differential activation of the human farnesoid X receptor depends on the pattern of expressed isoforms and the bile acid pool composition.

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12 December 2020

The long-term effect of ursodeoxycholic acid on laboratory liver parameters in biochemically non-advanced primary biliary cirrhosis

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12 December 2020

Perspective: TGR5 (Gpbar-1) in liver physiology and disease

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12 December 2020

Farnesoid X receptor targeting to treat nonalcoholic steatohepatitis

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12 December 2020

Mechanistic insights into isoform-dependent and species-specific regulation of bile salt export pump by farnesoid X receptor

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12 December 2020

Effects of chenodeoxycholic acid and deoxycholic acid on cholesterol absorption and metabolism in humans

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12 December 2020

SIRT1 controls liver regeneration by regulating bile acid metabolism through farnesoid X receptor and mammalian target of rapamycin signaling.

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12 December 2020

Generation of multiple farnesoid-X-receptor isoforms through the use of alternative promoters

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12 December 2020

The bile acid sensor FXR regulates insulin transcription and secretion

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12 December 2020

Efficacy and safety of the farnesoid X receptor agonist obeticholic acid in patients with type 2 diabetes and nonalcoholic fatty liver disease

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12 December 2020

Time-restricted feeding without reducing caloric intake prevents metabolic diseases in mice fed a high-fat diet

1 reference

12 December 2020

Feedback regulation of bile acid synthesis in primary human hepatocytes: evidence that CDCA is the strongest inhibitor

1 reference

12 December 2020

Bile acid metabolites in serum: intraindividual variation and associations with coronary heart disease, metabolic syndrome and diabetes mellitus

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12 December 2020

Activation of bile salt nuclear receptor FXR is repressed by pro-inflammatory cytokines activating NF-κB signaling in the intestine.

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12 December 2020

Farnesoid X receptor antagonizes nuclear factor kappaB in hepatic inflammatory response

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12 December 2020

Mechanisms of STAT3 activation in the liver of FXR knockout mice

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12 December 2020

DCo(H2)ding the metabolic functions of SIRT1 in the intestine

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12 December 2020

Phosphorylation of farnesoid X receptor by protein kinase C promotes its transcriptional activity

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12 December 2020

In VivoImaging of Farnesoid X Receptor Activity Reveals the Ileum as the Primary Bile Acid Signaling Tissue

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12 December 2020

Genome-wide analysis of hepatic LRH-1 reveals a promoter binding preference and suggests a role in regulating genes of lipid metabolism in concert with FXR.

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12 December 2020

Protective effects of farnesoid X receptor (FXR) on hepatic lipid accumulation are mediated by hepatic FXR and independent of intestinal FGF15 signal

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12 December 2020

Bile acids acutely stimulate insulin secretion of mouse β-cells via farnesoid X receptor activation and K(ATP) channel inhibition

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12 December 2020

Bile acid-induced liver toxicity: relation to the hydrophobic-hydrophilic balance of bile acids.

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12 December 2020

DAX1 suppresses FXR transactivity as a novel co-repressor

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12 December 2020

The membrane protein ATPase class I type 8B member 1 signals through protein kinase C zeta to activate the farnesoid X receptor

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12 December 2020

The farnesoid X-activated receptor mediates bile acid activation of phospholipid transfer protein gene expression

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12 December 2020

Identification of a nuclear receptor for bile acids

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12 December 2020

Increase in serum total cholesterol and low-density lipoprotein cholesterol by high-dose chenodeoxycholic acid in patients with radiolucent gallstones significantly reversed during preventive low dose after gallstone dissolution

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12 December 2020

Spontaneous hepatocarcinogenesis in farnesoid X receptor-null mice

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12 December 2020

Activation of the nuclear receptor FXR enhances hepatocyte chemoprotection and liver tumor chemoresistance against genotoxic compounds.

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12 December 2020

FXR controls the tumor suppressor NDRG2 and FXR agonists reduce liver tumor growth and metastasis in an orthotopic mouse xenograft model

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12 December 2020

Expression of sterol 12alpha-hydroxylase alters bile acid pool composition in primary rat hepatocytes and in vivo

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12 December 2020

Expression and activation of the farnesoid X receptor in the vasculature

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12 December 2020

Small heterodimer partner overexpression partially protects against liver tumor development in farnesoid X receptor knockout mice.

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12 December 2020

Genome-wide binding and transcriptome analysis of human farnesoid X receptor in primary human hepatocytes

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12 December 2020

AMPK: a nutrient and energy sensor that maintains energy homeostasis

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12 December 2020

FXR mediates a chromatin looping in the GR promoter thus promoting the resolution of colitis in rodents.

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12 December 2020

Bile acid-activated nuclear receptor FXR suppresses apolipoprotein A-I transcription via a negative FXR response element

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12 December 2020

FGF-receptor substrate 2 functions as a molecular sensor integrating external regulatory signals into the FGF pathway

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12 December 2020

Bile acid reduces the secretion of very low density lipoprotein by repressing microsomal triglyceride transfer protein gene expression mediated by hepatocyte nuclear factor-4.

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12 December 2020

Farnesoid X receptor activation mediates head-to-tail chromatin looping in the Nr0b2 gene encoding small heterodimer partner.

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12 December 2020

Bile acids as modulators of gut microbiota linking dietary habits and inflammatory bowel disease: a potentially dangerous liaison

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12 December 2020

Promotion of liver regeneration/repair by farnesoid X receptor in both liver and intestine in mice

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12 December 2020

Molecular basis for feedback regulation of bile acid synthesis by nuclear receptors

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12 December 2020

Farnesoid X receptor agonists suppress hepatic apolipoprotein CIII expression

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12 December 2020

A chemical, genetic, and structural analysis of the nuclear bile acid receptor FXR

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12 December 2020

The farnesoid X receptor controls gene expression in a ligand- and promoter-selective fashion

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12 December 2020

Gut microbiota regulates bile acid metabolism by reducing the levels of tauro-beta-muricholic acid, a naturally occurring FXR antagonist

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12 December 2020

The effect of ursodeoxycholic acid on the florid duct lesion of primary biliary cirrhosis

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12 December 2020

Synergistic growth inhibition of human hepatocellular carcinoma cells by acyclic retinoid and GW4064, a farnesoid X receptor ligand.

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12 December 2020

Regulation of host weight gain and lipid metabolism by bacterial bile acid modification in the gut

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12 December 2020

Fasting serum taurine-conjugated bile acids are elevated in type 2 diabetes and do not change with intensification of insulin

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12 December 2020

Bile salt biotransformations by human intestinal bacteria

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12 December 2020

Bile acids regulate the ontogenic expression of ileal bile acid binding protein in the rat via the farnesoid X receptor

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12 December 2020

Farnesoid X receptor deficiency improves glucose homeostasis in mouse models of obesity

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12 December 2020

Synthetic farnesoid X receptor agonists induce high-density lipoprotein-mediated transhepatic cholesterol efflux in mice and monkeys and prevent atherosclerosis in cholesteryl ester transfer protein transgenic low-density lipoprotein receptor (-/-)

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12 December 2020

Farnesoid X receptor alleviates age-related proliferation defects in regenerating mouse livers by activating forkhead box m1b transcription

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12 December 2020

Ligand-dependent activation of the farnesoid X-receptor directs arginine methylation of histone H3 by CARM1

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12 December 2020

Glucocorticoid receptor mediates the gluconeogenic activity of the farnesoid X receptor in the fasting condition.

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12 December 2020

Fxr(-/-) mice adapt to biliary obstruction by enhanced phase I detoxification and renal elimination of bile acids

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12 December 2020

Separating Tumorigenicity from Bile Acid Regulatory Activity for Endocrine Hormone FGF19.

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12 December 2020

Downregulation of nuclear receptor FXR is associated with multiple malignant clinicopathological characteristics in human hepatocellular carcinoma

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12 December 2020

Activation of the nuclear receptor FXR induces fibrinogen expression: a new role for bile acid signaling.

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12 December 2020

Genome-wide tissue-specific farnesoid X receptor binding in mouse liver and intestine.

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12 December 2020

Farnesoid X receptor deficiency in mice leads to increased intestinal epithelial cell proliferation and tumor development

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12 December 2020

The methyl transferase PRMT1 functions as co-activator of farnesoid X receptor (FXR)/9-cis retinoid X receptor and regulates transcription of FXR responsive genes

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12 December 2020

Hepatoprotection by the farnesoid X receptor agonist GW4064 in rat models of intra- and extrahepatic cholestasis

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12 December 2020

Chenodeoxycholic acid-mediated activation of the farnesoid X receptor negatively regulates hydroxysteroid sulfotransferase.

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12 December 2020

Microbiota modification with probiotics induces hepatic bile acid synthesis via downregulation of the Fxr-Fgf15 axis in mice.

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12 December 2020

Hepatocyte nuclear factor 4 alpha and farnesoid X receptor co-regulates gene transcription in mouse livers on a genome-wide scale

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12 December 2020

A regulatory cascade of the nuclear receptors FXR, SHP-1, and LRH-1 represses bile acid biosynthesis

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12 December 2020

Bile acid sequestrants: more than simple resins

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12 December 2020

Efficacy and safety of colesevelam in patients with type 2 diabetes mellitus and inadequate glycemic control receiving insulin-based therapy

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12 December 2020

Mechanism of tissue-specific farnesoid X receptor in suppressing the expression of genes in bile-acid synthesis in mice

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12 December 2020

FXR: the key to benefits in bariatric surgery?

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12 December 2020

Structural basis for bile acid binding and activation of the nuclear receptor FXR

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12 December 2020

Deciphering the nuclear bile acid receptor FXR paradigm

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12 December 2020

Peroxisome proliferator-activated receptor-gamma coactivator 1alpha (PGC-1alpha) regulates triglyceride metabolism by activation of the nuclear receptor FXR

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12 December 2020

Reduced hepatic expression of farnesoid X receptor in hereditary cholestasis associated to mutation in ATP8B1

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12 December 2020

Intrahepatic cholestasis of pregnancy: Amelioration of pruritus by UDCA is associated with decreased progesterone disulphates in urine

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12 December 2020

Lack of biliary lipid excretion in the little skate, Raja erinacea, indicates the absence of functional Mdr2, Abcg5, and Abcg8 transporters

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12 December 2020

Effect of complete sulfation of bile acids on bile formation: role of conjugation and number of sulfate groups

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12 December 2020

Ageing Fxr deficient mice develop increased energy expenditure, improved glucose control and liver damage resembling NASH

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12 December 2020

Role of farnesoid X receptor in determining hepatic ABC transporter expression and liver injury in bile duct-ligated mice

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12 December 2020

Transcriptional regulation of autophagy by an FXR-CREB axis

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12 December 2020

Nutrient-sensing nuclear receptors coordinate autophagy

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12 December 2020

Farnesoid X receptor is essential for normal glucose homeostasis

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12 December 2020

Targeted profiling of circulating and hepatic bile acids in human, mouse, and rat using a UPLC-MRM-MS-validated method

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12 December 2020

Interactions in the transcriptional regulation exerted by Stat5 and by members of the steroid hormone receptor family

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12 December 2020

ASCOM controls farnesoid X receptor transactivation through its associated histone H3 lysine 4 methyltransferase activity

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12 December 2020

Ursodiol for the long-term treatment of primary biliary cirrhosis. The UDCA-PBC Study Group.

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12 December 2020

Metformin interferes with bile acid homeostasis through AMPK-FXR crosstalk.

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12 December 2020

Diurnal regulation of MTP and plasma triglyceride by CLOCK is mediated by SHP.

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12 December 2020

Bile acids activate fibroblast growth factor 19 signaling in human hepatocytes to inhibit cholesterol 7alpha-hydroxylase gene expression

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12 December 2020

FXR activation reverses insulin resistance and lipid abnormalities and protects against liver steatosis in Zucker (fa/fa) obese rats

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12 December 2020

Interaction of the glucocorticoid receptor and the chicken ovalbumin upstream promoter-transcription factor II (COUP-TFII): implications for the actions of glucocorticoids on glucose, lipoprotein, and xenobiotic metabolism

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12 December 2020

Identification of the DNA binding specificity and potential target genes for the farnesoid X-activated receptor

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12 December 2020

Hepatic deletion of SIRT1 decreases hepatocyte nuclear factor 1α/farnesoid X receptor signaling and induces formation of cholesterol gallstones in mice.

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12 December 2020

Microbiota and diabetes: an evolving relationship.

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12 December 2020

Bile acids and the gut microbiome

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12 December 2020

Alpha-crystallin is a target gene of the farnesoid X-activated receptor in human livers

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12 December 2020

The bile acid membrane receptor TGR5: a novel pharmacological target in metabolic, inflammatory and neoplastic disorders.

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12 December 2020

Bile acid biosynthesis

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12 December 2020

Functional roles of enhancer RNAs for oestrogen-dependent transcriptional activation

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12 December 2020

Different effects of chenodeoxycholic acid and ursodeoxycholic acid on serum lipoprotein concentrations in patients with radiolucent gallstones

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12 December 2020

Dehydroepiandrosterone sulfotransferase gene induction by bile acid activated farnesoid X receptor

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12 December 2020

Regulation of drug transporters by the farnesoid X receptor in mice

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12 December 2020

Correlation of farnesoid X receptor coactivator recruitment and cholesterol 7alpha-hydroxylase gene repression by bile acids

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12 December 2020

Farnesoid X receptor activation increases cholesteryl ester transfer protein expression in humans and transgenic mice

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12 December 2020

Cytoplasmic tyrosine phosphatase Shp2 coordinates hepatic regulation of bile acid and FGF15/19 signaling to repress bile acid synthesis

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12 December 2020

Subcellular organization of bile acid amidation in human liver: a key issue in regulating the biosynthesis of bile salts

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12 December 2020

Farnesoid X receptor represses hepatic lipase gene expression

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12 December 2020

Farnesoid X receptor deficiency induces nonalcoholic steatohepatitis in low-density lipoprotein receptor-knockout mice fed a high-fat diet

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12 December 2020

TRRAP as a hepatic coactivator of LXR and FXR function

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12 December 2020

Hepatic glucose sensing is required to preserve β cell glucose competence

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12 December 2020

The nuclear receptor SHP mediates inhibition of hepatic stellate cells by FXR and protects against liver fibrosis

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12 December 2020

Bile acids lower triglyceride levels via a pathway involving FXR, SHP, and SREBP-1c

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12 December 2020

Bile acids: natural ligands for an orphan nuclear receptor

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12 December 2020

FXR ligands protect against hepatocellular inflammation via SOCS3 induction

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12 December 2020

Identification of bile acid coenzyme A synthetase in rat kidney

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12 December 2020

Increased activation of the Wnt/β-catenin pathway in spontaneous hepatocellular carcinoma observed in farnesoid X receptor knockout mice

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12 December 2020

Farnesoid X receptor induces GLUT4 expression through FXR response element in the GLUT4 promoter

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12 December 2020

Molecular and functional characterization of bile acid transport in human hepatoblastoma HepG2 cells

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12 December 2020

Colesevelam improved lipoprotein particle subclasses in patients with prediabetes and primary hyperlipidaemia

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12 December 2020

Microbiome remodelling leads to inhibition of intestinal farnesoid X receptor signalling and decreased obesity.

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12 December 2020

Histone H3K4 trimethylation by MLL3 as part of ASCOM complex is critical for NR activation of bile acid transporter genes and is downregulated in cholestasis

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12 December 2020

The p300 acetylase is critical for ligand-activated farnesoid X receptor (FXR) induction of SHP.

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12 December 2020

Vitamin D receptor as an intestinal bile acid sensor

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12 December 2020

Key discoveries in bile acid chemistry and biology and their clinical applications: history of the last eight decades

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12 December 2020

The transrepressive activity of peroxisome proliferator-activated receptor alpha is necessary and sufficient to prevent liver fibrosis in mice

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12 December 2020

An increased flux through the glucose 6-phosphate pool in enterocytes delays glucose absorption in Fxr-/- mice

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12 December 2020

The farnesoid X-receptor is an essential regulator of cholesterol homeostasis

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12 December 2020

Loss of functional farnesoid X receptor increases atherosclerotic lesions in apolipoprotein E-deficient mice

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12 December 2020

Targeted disruption of the nuclear receptor FXR/BAR impairs bile acid and lipid homeostasis.

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12 December 2020

The bile acid nuclear receptor FXR and the bile acid binding protein IBABP are differently expressed in colon cancer

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12 December 2020

Regulation of multidrug resistance-associated protein 2 (ABCC2) by the nuclear receptors pregnane X receptor, farnesoid X-activated receptor, and constitutive androstane receptor

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12 December 2020

SUMOylation of the farnesoid X receptor (FXR) regulates the expression of FXR target genes

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12 December 2020

The enzymes, regulation, and genetics of bile acid synthesis

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12 December 2020

In vitro farnesoid X receptor ligand sensor assay using surface plasmon resonance and based on ligand-induced coactivator association

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12 December 2020

Bile acids induce cdx2 expression through the farnesoid x receptor in gastric epithelial cells

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12 December 2020

Bile salt transporters

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12 December 2020

Direct methylation of FXR by Set7/9, a lysine methyltransferase, regulates the expression of FXR target genes

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12 December 2020

Identification of 15d-PGJ2 as an antagonist of farnesoid X receptor: molecular modeling with biological evaluation

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12 December 2020

Bile acid receptor agonist GW4064 regulates PPARγ coactivator-1α expression through estrogen receptor-related receptor α

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12 December 2020

Genome-wide interrogation of hepatic FXR reveals an asymmetric IR-1 motif and synergy with LRH-1.

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12 December 2020

Regulation of FXR transcriptional activity in health and disease: Emerging roles of FXR cofactors and post-translational modifications

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12 December 2020

The hinge region of the human estrogen receptor determines functional synergy between AF-1 and AF-2 in the quantitative response to estradiol and tamoxifen.

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12 December 2020

Natural structural variants of the nuclear receptor farnesoid X receptor affect transcriptional activation

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12 December 2020

Selective Activation of Nuclear Bile Acid Receptor FXR in the Intestine Protects Mice Against Cholestasis

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12 December 2020

FXR is a molecular target for the effects of vertical sleeve gastrectomy

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12 December 2020

Upregulation of a basolateral FXR-dependent bile acid efflux transporter OSTalpha-OSTbeta in cholestasis in humans and rodents

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12 December 2020

The combination of ursodeoxycholic acid and methotrexate for patients with primary biliary cirrhosis: the results of a pilot study

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12 December 2020

Loss of FXR protects against diet-induced obesity and accelerates liver carcinogenesis in ob/ob mice

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12 December 2020

Involvement of corepressor complex subunit GPS2 in transcriptional pathways governing human bile acid biosynthesis

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12 December 2020

A randomized, double-blind, placebo-controlled trial of ursodeoxycholic acid in primary biliary cirrhosis.

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12 December 2020

Studies in mice, hamsters, and rats demonstrate that repression of hepatic apoA-I expression by taurocholic acid in mice is not mediated by the farnesoid-X-receptor

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12 December 2020

FXR deficiency causes reduced atherosclerosis in Ldlr-/- mice

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12 December 2020

The Canadian Multicenter Double-blind Randomized Controlled Trial of ursodeoxycholic acid in primary biliary cirrhosis.

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12 December 2020

Farnesoid X receptor immunolocalization in reproductive tissues of adult female rabbits.

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12 December 2020

Syndecan-1 expression is regulated in an isoform-specific manner by the farnesoid-X receptor

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12 December 2020

Intestine-specific deletion of SIRT1 in mice impairs DCoH2-HNF-1α-FXR signaling and alters systemic bile acid homeostasis.

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12 December 2020

FXR induces the UGT2B4 enzyme in hepatocytes: a potential mechanism of negative feedback control of FXR activity

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12 December 2020

Results of the glucose-lowering effect of WelChol study (GLOWS): a randomized, double-blind, placebo-controlled pilot study evaluating the effect of colesevelam hydrochloride on glycemic control in subjects with type 2 diabetes

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12 December 2020

The nuclear receptor PXR is a lithocholic acid sensor that protects against liver toxicity

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12 December 2020

Bile acid receptors as targets for the treatment of dyslipidemia and cardiovascular disease

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12 December 2020

Colesevelam HCl improves glycemic control and reduces LDL cholesterol in patients with inadequately controlled type 2 diabetes on sulfonylurea-based therapy

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12 December 2020

Progressive familial intrahepatic cholestasis, type 1, is associated with decreased farnesoid X receptor activity

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12 December 2020

Protective effects of 6-ethyl chenodeoxycholic acid, a farnesoid X receptor ligand, in estrogen-induced cholestasis

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12 December 2020

Discovery and SAR study of hydroxyacetophenone derivatives as potent, non-steroidal farnesoid X receptor (FXR) antagonists

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12 December 2020

A G protein-coupled receptor responsive to bile acids

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12 December 2020

Development of time resolved fluorescence resonance energy transfer-based assay for FXR antagonist discovery

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12 December 2020

FXR acetylation is normally dynamically regulated by p300 and SIRT1 but constitutively elevated in metabolic disease states

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12 December 2020

Increase in the ileal absorption rate of sodium taurocholate in germ-free or conventional rats given an amylomaize-starch diet

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12 December 2020

Diurnal variations of mouse plasma and hepatic bile acid concentrations as well as expression of biosynthetic enzymes and transporters

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12 December 2020

Intestinal FXR-mediated FGF15 production contributes to diurnal control of hepatic bile acid synthesis in mice

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12 December 2020

Farnesoid X receptor represses hepatic human APOA gene expression

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12 December 2020

Glucose sensing O-GlcNAcylation pathway regulates the nuclear bile acid receptor farnesoid X receptor (FXR).

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12 December 2020

Hepatocarcinogenesis in FXR-/- mice mimics human HCC progression that operates through HNF1α regulation of FXR expression

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12 December 2020

Liver receptor homologue-1 mediates species- and cell line-specific bile acid-dependent negative feedback regulation of the apical sodium-dependent bile acid transporter

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12 December 2020

FXR regulates liver repair after CCl4-induced toxic injury

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12 December 2020

Kinetics of hepatic bile acid handling in cholestatic liver disease: effect of ursodeoxycholic acid.

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12 December 2020

Design, synthesis, and evaluation of non-steroidal farnesoid X receptor (FXR) antagonist

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12 December 2020

A nontumorigenic variant of FGF19 treats cholestatic liver diseases.

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12 December 2020

Glucose regulates the expression of the farnesoid X receptor in liver

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12 December 2020

Glycine and taurine conjugation of bile acids by a single enzyme. Molecular cloning and expression of human liver bile acid CoA:amino acid N-acyltransferase

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12 December 2020

Binding mechanism of the farnesoid X receptor marine antagonist suvanine reveals a strategy to forestall drug modulation on nuclear receptors. Design, synthesis, and biological evaluation of novel ligands.

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12 December 2020

Activation of the farnesoid X receptor represses PCSK9 expression in human hepatocytes

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12 December 2020

Role of nuclear receptors and hepatocyte-enriched transcription factors for Ntcp repression in biliary obstruction in mouse liver

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12 December 2020

Genomic analysis of hepatic farnesoid X receptor binding sites reveals altered binding in obesity and direct gene repression by farnesoid X receptor in mice

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12 December 2020

The hepatic orosomucoid/α1-acid glycoprotein gene cluster is regulated by the nuclear bile acid receptor FXR.

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12 December 2020

Benefit of farnesoid X receptor inhibition in obstructive cholestasis

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12 December 2020

Potency of individual bile acids to regulate bile acid synthesis and transport genes in primary human hepatocyte cultures

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12 December 2020

Feedback regulation of bile acid synthesis in human liver: importance of HNF-4alpha for regulation of CYP7A1.

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12 December 2020

Compensatory induction of liver efflux transporters in response to ANIT-induced liver injury is impaired in FXR-null mice.

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12 December 2020

Fibroblast growth factor 15 functions as an enterohepatic signal to regulate bile acid homeostasis

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12 December 2020

Nuclear receptor-dependent bile acid signaling is required for normal liver regeneration

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12 December 2020

Lowering bile acid pool size with a synthetic farnesoid X receptor (FXR) agonist induces obesity and diabetes through reduced energy expenditure

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12 December 2020

Guggulsterone is a farnesoid X receptor antagonist in coactivator association assays but acts to enhance transcription of bile salt export pump

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12 December 2020

Separating transrepression and transactivation: a distressing divorce for the glucocorticoid receptor?

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12 December 2020

The nuclear receptor FXR is expressed in pancreatic beta-cells and protects human islets from lipotoxicity

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12 December 2020

The farnesoid X receptor modulates adiposity and peripheral insulin sensitivity in mice

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12 December 2020

Systemic gut microbial modulation of bile acid metabolism in host tissue compartments

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12 December 2020

The bile acid receptor FXR is a modulator of intestinal innate immunity

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12 December 2020

Lithocholic acid decreases expression of UGT2B7 in Caco-2 cells: a potential role for a negative farnesoid X receptor response element

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12 December 2020

Cisplatin-induced chemoresistance in colon cancer cells involves FXR-dependent and FXR-independent up-regulation of ABC proteins.

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12 December 2020

Ku proteins function as corepressors to regulate farnesoid X receptor-mediated gene expression

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12 December 2020

Higher circulating bile acid concentrations in obese patients with type 2 diabetes.

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12 December 2020

Enterohepatic circulation of bile salts in farnesoid X receptor-deficient mice: efficient intestinal bile salt absorption in the absence of ileal bile acid-binding protein

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12 December 2020

Activation of the nuclear receptor FXR improves hyperglycemia and hyperlipidemia in diabetic mice

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12 December 2020

The farnesoid X receptor modulates hepatic carbohydrate metabolism during the fasting-refeeding transition.

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12 December 2020

The impact of farnesoid X receptor activation on intestinal permeability in inflammatory bowel disease

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12 December 2020

Regulation of antibacterial defense in the small intestine by the nuclear bile acid receptor

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12 December 2020

Isolation of proteins that interact specifically with the retinoid X receptor: two novel orphan receptors

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12 December 2020

Farnesoid X receptor agonist WAY-362450 attenuates liver inflammation and fibrosis in murine model of non-alcoholic steatohepatitis.

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12 December 2020

Turnover and nature of fecal bile acids in germfree and infected rats fed cholic acid-24-14C; bile acids and steroids 41

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12 December 2020

Farnesoid X receptor and bile salts are involved in transcriptional regulation of the gene encoding the human bile salt export pump

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12 December 2020

Expression of the nuclear bile acid receptor/farnesoid X receptor is reduced in human colon carcinoma compared to nonneoplastic mucosa independent from site and may be associated with adverse prognosis.

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12 December 2020

Disturbances of bile acid metabolism in cholestasis

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12 December 2020

Retinoid X receptor (RXR) agonist-induced antagonism of farnesoid X receptor (FXR) activity due to absence of coactivator recruitment and decreased DNA binding

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12 December 2020

Spontaneous development of liver tumors in the absence of the bile acid receptor farnesoid X receptor

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12 December 2020

Nuclear bile acid receptor FXR protects against intestinal tumorigenesis

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12 December 2020

Combined functional variants of hepatobiliary transporters and FXR aggravate intrahepatic cholestasis of pregnancy

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12 December 2020

Nuclear receptors HNF4α and LRH-1 cooperate in regulating Cyp7a1 in vivo

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12 December 2020

Farnesoid X receptor inhibits the transcriptional activity of carbohydrate response element binding protein in human hepatocytes.

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12 December 2020

10.1007/S00018-014-1805-Y

Identifiers

DOI

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1 September 2017

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