(Q38399347)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25830673%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

review article

1 reference

title

Structures of Ras superfamily effector complexes: What have we learnt in two decades? (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25830673%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25830673%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

author name string

Darerca Owen

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25830673%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

publication date

1 March 2015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25830673%20AND%20SRC:MED&resulttype=core&format=json

Critical Reviews in Biochemistry and Molecular Biology

4 March 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25830673%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

volume

50

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25830673%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25830673%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

page(s)

85-133

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25830673%20AND%20SRC:MED&resulttype=core&format=json

Structure of Cdc42 in complex with the GTPase-binding domain of the 'Wiskott-Aldrich syndrome' protein

4 March 2020

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Regulation of reactive oxygen species generation in cell signaling

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The structure of binder of Arl2 (BART) reveals a novel G protein binding domain: implications for function

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ADP-ribosylation factor 6 acts as an allosteric activator for the folded but not disordered cholera toxin A1 polypeptide.

21 January 2018

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A Dual Binding Mode for RhoGTPases in Plexin Signalling

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The structural basis of the activation of Ras by Sos

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Entamoeba histolytica Rho1 Regulates Actin Polymerization through a Divergent, Diaphanous-Related Formin

21 January 2018

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Structural and mechanistic insights into ras association domains of phospholipase C epsilon

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Structural insights into formation of an active signaling complex between Rac and phospholipase C gamma 2

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Rab and Arl GTPase family members cooperate in the localization of the golgin GCC185.

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The GDI-like solubilizing factor PDEδ sustains the spatial organization and signalling of Ras family proteins

21 January 2018

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Elucidation of Rab27 recruitment by its effectors: structure of Rab27a bound to Exophilin4/Slp2-a

21 January 2018

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Structural Insights into a Unique Legionella pneumophila Effector LidA Recognizing Both GDP and GTP Bound Rab1 in Their Active State

21 January 2018

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Regulation of small GTPases by GEFs, GAPs, and GDIs

21 January 2018

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Structure of the nuclear transport complex karyopherin-beta2-Ran x GppNHp

21 January 2018

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The structure of the GGA1-GAT domain reveals the molecular basis for ARF binding and membrane association of GGAs

21 January 2018

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Structural biology of nucleocytoplasmic transport

21 January 2018

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The structure of the nuclear export receptor Cse1 in its cytosolic state reveals a closed conformation incompatible with cargo binding.

21 January 2018

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Structures of the tRNA export factor in the nuclear and cytosolic states

21 January 2018

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Cholera toxin: a paradigm for multi-functional engagement of cellular mechanisms (Review)

21 January 2018

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Three-dimensional structure of an oncogene protein: catalytic domain of human c-H-ras p21.

21 January 2018

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Structural and functional studies of the Ras-associating and pleckstrin-homology domains of Grb10 and Grb14

21 January 2018

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Structural Basis and Mechanism of Autoregulation in 3-Phosphoinositide-Dependent Grp1 Family Arf GTPase Exchange Factors

21 January 2018

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Golgi-localized GAP for Cdc42 functions downstream of ARF1 to control Arp2/3 complex and F-actin dynamics

21 January 2018

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Structural insights into the interaction of ROCKI with the switch regions of RhoA

21 January 2018

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Structural basis for Rab11-mediated recruitment of FIP3 to recycling endosomes

21 January 2018

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Structural basis of family-wide Rab GTPase recognition by rabenosyn-5

21 January 2018

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Solution structure of the Ras-binding domain of c-Raf-1 and identification of its Ras interaction surface

21 January 2018

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Chemical shift assignments and folding topology of the Ras-binding domain of human Raf-1 as determined by heteronuclear three-dimensional NMR spectroscopy.

21 January 2018

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The RalB-RLIP76 Complex Reveals a Novel Mode of Ral-Effector Interaction

21 January 2018

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Solution structure and dynamics of the small GTPase RalB in its active conformation: significance for effector protein binding

21 January 2018

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Nucleocytoplasmic transport: taking an inventory

21 January 2018

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Structural basis of the interaction between RalA and Sec5, a subunit of the sec6/8 complex

21 January 2018

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Structure of Cdc42 in a complex with the GTPase-binding domain of the cell polarity protein, Par6

21 January 2018

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The Structure of the Ternary Complex of Krev Interaction Trapped 1 (KRIT1) Bound to Both the Rap1 GTPase and the Heart of Glass (HEG1) Cytoplasmic Tail

21 January 2018

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KRIT-1/CCM1 is a Rap1 effector that regulates endothelial cell cell junctions

21 January 2018

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Equilibrium and kinetic measurements reveal rapidly reversible binding of Ras to Raf.

21 January 2018

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Structural basis for the nuclear export activity of Importin13

21 January 2018

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Ran-dependent nuclear export mediators: a structural perspective

21 January 2018

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The complex of Arl2-GTP and PDE delta: from structure to function

21 January 2018

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Exorcising the exocyst complex

21 January 2018

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Molecular studies of CtpA, the carboxyl-terminal processing protease for the D1 protein of the photosystem II reaction center in higher plants

21 January 2018

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VARP is recruited on to endosomes by direct interaction with retromer, where together they function in export to the cell surface

21 January 2018

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Structure of the Rho family GTP-binding protein Cdc42 in complex with the multifunctional regulator RhoGDI

21 January 2018

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Plexin structures are coming: opportunities for multilevel investigations of semaphorin guidance receptors, their cell signaling mechanisms, and functions

21 January 2018

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OCRL mutation analysis in Italian patients with Lowe syndrome

21 January 2018

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Structural basis for the interaction of Ras with RalGDS

21 January 2018

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Mutational analysis reveals a single binding interface between RhoA and its effector, PRK1.

21 January 2018

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Differential binding of RhoA, RhoB, and RhoC to protein kinase C-related kinase (PRK) isoforms PRK1, PRK2, and PRK3: PRKs have the highest affinity for RhoB.

21 January 2018

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The structural basis of Arf effector specificity: the crystal structure of ARF6 in a complex with JIP4

21 January 2018

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Arl2-GTP and Arl3-GTP regulate a GDI-like transport system for farnesylated cargo

21 January 2018

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A large-scale conformational change couples membrane recruitment to cargo binding in the AP2 clathrin adaptor complex

21 January 2018

1 reference

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Structures and mechanisms of vesicle coat components and multisubunit tethering complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2014.999191

p21-activated kinases: three more join the Pak.

21 January 2018

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https://api.crossref.org/works/10.3109%2F10409238.2014.999191

Crystal structure of rab11 in complex with rab11 family interacting protein 2

21 January 2018

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Exo84 and Sec5 are competitive regulatory Sec6/8 effectors to the RalA GTPase

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2014.999191

The cell-polarity protein Par6 links Par3 and atypical protein kinase C to Cdc42

21 January 2018

1 reference

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Mechanism of IRSp53 inhibition and combinatorial activation by Cdc42 and downstream effectors

21 January 2018

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https://api.crossref.org/works/10.3109%2F10409238.2014.999191

Phospholipase C(epsilon): a novel Ras effector

21 January 2018

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Structural biology of Arf and Rab GTPases' effector recruitment and specificity

21 January 2018

1 reference

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Structural basis for the exclusive specificity of Slac2-a/melanophilin for the Rab27 GTPases

21 January 2018

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https://api.crossref.org/works/10.3109%2F10409238.2014.999191

Specificity of Interactions between mDia Isoforms and Rho Proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2014.999191

Structure of the TPR domain of p67phox in complex with Rac.GTP

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2014.999191

The FYVE domain of early endosome antigen 1 is required for both phosphatidylinositol 3-phosphate and Rab5 binding. Critical role of this dual interaction for endosomal localization

21 January 2018

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https://api.crossref.org/works/10.3109%2F10409238.2014.999191

Structural basis for nuclear import complex dissociation by RanGTP

21 January 2018

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Structure of PAK1 in an autoinhibited conformation reveals a multistage activation switch

21 January 2018

1 reference

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Structural Basis for Small G Protein Effector Interaction of Ras-related Protein 1 (Rap1) and Adaptor Protein Krev Interaction Trapped 1 (KRIT1)

21 January 2018

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Thermodynamic and kinetic characterization of the interaction between the Ras binding domain of AF6 and members of the Ras subfamily

21 January 2018

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Interaction of Arl1-GTP with GRIP domains recruits autoantigens Golgin-97 and Golgin-245/p230 onto the Golgi

21 January 2018

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The structural basis of Rho effector recognition revealed by the crystal structure of human RhoA complexed with the effector domain of PKN/PRK1

21 January 2018

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Structural basis for Arf6-MKLP1 complex formation on the Flemming body responsible for cytokinesis.

21 January 2018

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Structural basis for membrane recruitment and allosteric activation of cytohesin family Arf GTPase exchange factors

21 January 2018

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Structural evidence for feedback activation by Ras.GTP of the Ras-specific nucleotide exchange factor SOS

21 January 2018

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Structural basis for the assembly of a nuclear export complex.

21 January 2018

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COP and clathrin-coated vesicle budding: different pathways, common approaches

21 January 2018

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Structural basis for ARF1-mediated recruitment of ARHGAP21 to Golgi membranes

21 January 2018

1 reference

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IRSp53 is an essential intermediate between Rac and WAVE in the regulation of membrane ruffling

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2014.999191

Molecular switch for signal transduction: structural differences between active and inactive forms of protooncogenic ras proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2014.999191

Structural basis for Rab GTPase recognition and endosome tethering by the C2H2 zinc finger of Early Endosomal Autoantigen 1 (EEA1)

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2014.999191

GTPase networks in membrane traffic

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2014.999191

The Rac1 polybasic region is required for interaction with its effector PRK1

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2014.999191

Crystal structure of the nuclear export receptor CRM1 in complex with Snurportin1 and RanGTP

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2014.999191

Structure of Cdc42 bound to the GTPase binding domain of PAK

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2014.999191

Structure of the GTPase-binding domain of Sec5 and elucidation of its Ral binding site

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2014.999191

Structure of the small G protein Cdc42 bound to the GTPase-binding domain of ACK

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2014.999191

BART is essential for nuclear retention of STAT3

21 January 2018

1 reference

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Structural basis for membrane binding specificity of the Bin/Amphiphysin/Rvs (BAR) domain of Arfaptin-2 determined by Arl1 GTPase

21 January 2018

1 reference

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The 2.2 A crystal structure of the Ras-binding domain of the serine/threonine kinase c-Raf1 in complex with Rap1A and a GTP analogue

21 January 2018

1 reference

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Ras/Rap effector specificity determined by charge reversal

21 January 2018

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https://api.crossref.org/works/10.3109%2F10409238.2014.999191

A high-resolution structure of the pre-microRNA nuclear export machinery

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2014.999191

Crystal structures of an intrinsically active cholera toxin mutant yield insight into the toxin activation mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2014.999191

Structural basis for the activation of cholera toxin by human ARF6-GTP

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2014.999191

Structural basis of Rab effector specificity: crystal structure of the small G protein Rab3A complexed with the effector domain of rabphilin-3A

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2014.999191

Molecular dissection of the interaction between the small G proteins Rac1 and RhoA and protein kinase C-related kinase 1 (PRK1)

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2014.999191

Residues in Cdc42 that specify binding to individual CRIB effector proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2014.999191

Crystal structure and functional analysis of Ras binding to its effector phosphoinositide 3-kinase gamma

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2014.999191

Structure of the guanine-nucleotide-binding domain of the Ha-ras oncogene product p21 in the triphosphate conformation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2014.999191

Structural basis for Arl1-dependent targeting of homodimeric GRIP domains to the Golgi apparatus

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2014.999191

Inositol 5-phosphatases: insights from the Lowe syndrome protein OCRL.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2014.999191

The small GTPase ARL2 is required for cytokinesis in Trypanosoma brucei

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2014.999191

Structural basis of myosin V Rab GTPase-dependent cargo recognition

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2014.999191

Structural Basis for the Interaction of the Adaptor Protein Grb14 with Activated Ras

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2014.999191

PDZ domain proteins: scaffolds for signaling complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2014.999191

Structural basis for recruitment of Rab6-interacting protein 1 to Golgi via a RUN domain

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2014.999191

Structural basis for recruitment and activation of the AP-1 clathrin adaptor complex by Arf1

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2014.999191

Role of phosphoinositide 3-OH kinase in cell transformation and control of the actin cytoskeleton by Ras

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2014.999191

The Ras protein superfamily: evolutionary tree and role of conserved amino acids

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2014.999191

Structural and mechanistic insights into the interaction between Rho and mammalian Dia.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2014.999191

RhoA effector mutants reveal distinct effector pathways for cytoskeletal reorganization, SRF activation and transformation.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2014.999191

The binding of Varp to VAMP7 traps VAMP7 in a closed, fusogenically inactive conformation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2014.999191

Pleckstrin homology (PH) like domains - versatile modules in protein-protein interaction platforms

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2014.999191

Protein LidA from Legionella is a Rab GTPase supereffector

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2014.999191

ARL2 and BART enter mitochondria and bind the adenine nucleotide transporter

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2014.999191

Molecular mechanism of membrane recruitment of GGA by ARF in lysosomal protein transport

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2014.999191

Structural basis for Rab11-dependent membrane recruitment of a family of Rab11-interacting protein 3 (FIP3)/Arfophilin-1

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2014.999191

Structural insights into semaphorins and their receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2014.999191

The pleckstrin homology domain of phospholipase C-beta2 as an effector site for Rac.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2014.999191

Arf GTPase regulation through cascade mechanisms and positive feedback loops

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2014.999191

Novel type of Ras effector interaction established between tumour suppressor NORE1A and Ras switch II

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2014.999191

Structure of the GAT domain of human GGA1: A syntaxin amino-terminal domain fold in an endosomal trafficking adaptor

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2014.999191

The structural basis of Arfaptin-mediated cross-talk between Rac and Arf signalling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2014.999191

Binding of Rac1, Rnd1, and RhoD to a Novel Rho GTPase Interaction Motif Destabilizes Dimerization of the Plexin-B1 Effector Domain

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2014.999191

Structure and function of the intracellular region of the plexin-b1 transmembrane receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2014.999191

The guanine nucleotide-binding switch in three dimensions

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2014.999191

Structural view of the Ran-Importin beta interaction at 2.3 A resolution

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2014.999191

Structure of a Ran-binding domain complexed with Ran bound to a GTP analogue: implications for nuclear transport

21 January 2018

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https://api.crossref.org/works/10.3109%2F10409238.2014.999191

Mammalian Ras interacts directly with the serine/threonine kinase Raf

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2014.999191

Rac Regulates Its Effector Phospholipase C 2 through Interaction with a Split Pleckstrin Homology Domain

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2014.999191

Structural basis of Rnd1 binding to plexin Rho GTPase binding domains (RBDs)

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2014.999191

Molecular dissection of Rab11 binding from coiled-coil formation in the Rab11-FIP2 C-terminal domain

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2014.999191

Multiple Ras functions can contribute to mammalian cell transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2014.999191

Structural basis for recruitment of GRIP domain golgin-245 by small GTPase Arl1

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2014.999191

Structural basis for recruitment of RILP by small GTPase Rab7

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2014.999191

Rap1-interacting adapter molecule (RIAM) associates with the plasma membrane via a proximity detector

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2014.999191

Structural basis for the Rho- and phosphoinositide-dependent localization of the exocyst subunit Sec3

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2014.999191

A Structure-Based Mechanism for Arf1-Dependent Recruitment of Coatomer to Membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2014.999191

The structure of Rap1 in complex with RIAM reveals specificity determinants and recruitment mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2014.999191

The three-dimensional crystal structure of cholera toxin

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2014.999191

Crystal structure of the ARL2-GTP-BART complex reveals a novel recognition and binding mode of small GTPase with effector

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2014.999191

Varp is a Rab21 guanine nucleotide exchange factor and regulates endosome dynamics

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2014.999191

A conserved negative regulatory region in alphaPAK: inhibition of PAK kinases reveals their morphological roles downstream of Cdc42 and Rac1.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2014.999191

Crystal structure of the human GGA1 GAT domain

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2014.999191

Structural basis of Rab5-Rabaptin5 interaction in endocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2014.999191

Crystal structure of Rac1 bound to its effector phospholipase C-β2

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2014.999191

10.3109/10409238.2014.999191

21 January 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25830673%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

1 reference