(Q38517896)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26048892%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

review article

1 reference

title

A Perspective on the Future of High-Throughput RNAi Screening: Will CRISPR Cut Out the Competition or Can RNAi Help Guide the Way? (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26048892%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

0 references

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26048892%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

author name string

Simon Woodcock

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26048892%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

publication date

5 June 2015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26048892%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biomolecular Screening

16 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26048892%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

volume

20

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26048892%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

page(s)

1040-1051

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26048892%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

issue

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26048892%20AND%20SRC:MED&resulttype=core&format=json

Yeast genomics and drug target identification

16 February 2020

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High-throughput RNAi in Caenorhabditis elegans: genome-wide screens and functional genomics

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21 January 2018

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Functional genomics in Drosophila models of human disease

21 January 2018

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Fishing for function: zebrafish BAC transgenics for functional genomics

21 January 2018

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Functional genomics in mice by tagged sequence mutagenesis

21 January 2018

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Functional genomics to new drug targets

21 January 2018

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Functional genomic and high-content screening for target discovery and deconvolution

21 January 2018

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Gene-trap mutagenesis: past, present and beyond

21 January 2018

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Ten years of gene targeting: targeted mouse mutants, from vector design to phenotype analysis

21 January 2018

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Northern blot analysis for detection and quantification of RNA in pancreatic cancer cells and tissues

21 January 2018

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Discovery of novel targets with high throughput RNA interference screening

21 January 2018

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RNAi screening comes of age: improved techniques and complementary approaches

21 January 2018

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Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans

21 January 2018

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The silent revolution: RNA interference as basic biology, research tool, and therapeutic

21 January 2018

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Beyond RNAi: antiviral defense strategies in Drosophila and mosquito

21 January 2018

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siRNA vs. shRNA: similarities and differences

21 January 2018

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A kinase shRNA screen links LATS2 and the pRB tumor suppressor

21 January 2018

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An RNAi-based genetic screen for oxidative stress resistance reveals retinol saturase as a mediator of stress resistance.

21 January 2018

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Systems analysis of quantitative shRNA-library screens identifies regulators of cell adhesion

21 January 2018

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A genome-wide RNAi screen identifies multiple synthetic lethal interactions with the Ras oncogene

21 January 2018

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A large scale shRNA barcode screen identifies the circadian clock component ARNTL as putative regulator of the p53 tumor suppressor pathway

21 January 2018

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A genome-wide short hairpin RNA screening of jurkat T-cells for human proteins contributing to productive HIV-1 replication

21 January 2018

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A functional genome-wide RNAi screen identifies TAF1 as a regulator for apoptosis in response to genotoxic stress

21 January 2018

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Genome-wide siRNA screen identifies SMCX, EP400, and Brd4 as E2-dependent regulators of human papillomavirus oncogene expression

21 January 2018

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Genome-wide RNAi screen identifies human host factors crucial for influenza virus replication.

21 January 2018

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Genome-wide functional analysis of human cell-cycle regulators.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057115590069

High-throughput RNA interference screening using pooled shRNA libraries and next generation sequencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057115590069

A computational study of off-target effects of RNA interference

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057115590069

Systematic analysis of RNAi reports identifies dismal commonality at gene-level and reveals an unprecedented enrichment in pooled shRNA screens

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057115590069

Nucleotide sequence of the iap gene, responsible for alkaline phosphatase isozyme conversion in Escherichia coli, and identification of the gene product

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057115590069

Multiplex genome engineering using CRISPR/Cas systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057115590069

RNA-guided human genome engineering via Cas9

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057115590069

Enhanced efficiency of human pluripotent stem cell genome editing through replacing TALENs with CRISPRs

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057115590069

Evolution and classification of the CRISPR-Cas systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057115590069

CRISPR-mediated adaptive immune systems in bacteria and archaea

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057115590069

Genome engineering using the CRISPR-Cas9 system

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057115590069

Targeting DNA With Fingers and TALENs

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057115590069

TALENs: a widely applicable technology for targeted genome editing

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057115590069

Precision genome engineering with programmable DNA-nicking enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057115590069

Targeted chromosomal duplications and inversions in the human genome using zinc finger nucleases

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057115590069

CRISPR-mediated direct mutation of cancer genes in the mouse liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057115590069

Prevention of muscular dystrophy in mice by CRISPR/Cas9-mediated editing of germline DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057115590069

Generation of mouse models of myeloid malignancy with combinatorial genetic lesions using CRISPR-Cas9 genome editing.

21 January 2018

1 reference

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Genetic screens in human cells using the CRISPR-Cas9 system

21 January 2018

1 reference

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High-throughput screening of a CRISPR/Cas9 library for functional genomics in human cells

21 January 2018

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Genome-wide recessive genetic screening in mammalian cells with a lentiviral CRISPR-guide RNA library

21 January 2018

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Genome-scale CRISPR-Cas9 knockout screening in human cells

21 January 2018

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Double nicking by RNA-guided CRISPR Cas9 for enhanced genome editing specificity

21 January 2018

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DNA single-strand break repair

21 January 2018

1 reference

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Mammalian base excision repair: the forgotten archangel

21 January 2018

1 reference

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A CRISPR CASe for high-throughput silencing

21 January 2018

1 reference

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Repurposing CRISPR as an RNA-guided platform for sequence-specific control of gene expression

21 January 2018

1 reference

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CRISPR interference (CRISPRi) for sequence-specific control of gene expression

21 January 2018

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Multiplexed activation of endogenous genes by CRISPR-on, an RNA-guided transcriptional activator system

21 January 2018

1 reference

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CRISPR-mediated modular RNA-guided regulation of transcription in eukaryotes

21 January 2018

1 reference

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Genome-Scale CRISPR-Mediated Control of Gene Repression and Activation

21 January 2018

1 reference

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A protein-tagging system for signal amplification in gene expression and fluorescence imaging

21 January 2018

1 reference

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Repurposing CRISPR/Cas9 for in situ functional assays.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057115590069

CRISPR-Cas9 knockin mice for genome editing and cancer modeling

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057115590069

Tiam1-Rac signaling counteracts Eg5 during bipolar spindle assembly to facilitate chromosome congression

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057115590069

Enhancing and confirming the specificity of RNAi experiments

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057115590069

Protospacer recognition motifs: mixed identities and functional diversity

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057115590069

DNA targeting specificity of RNA-guided Cas9 nucleases

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057115590069

Expansion of the CRISPR-Cas9 genome targeting space through the use of H1 promoter-expressed guide RNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057115590069

Phylogeny of Cas9 determines functional exchangeability of dual-RNA and Cas9 among orthologous type II CRISPR-Cas systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057115590069

Efficient genome engineering in human pluripotent stem cells using Cas9 from Neisseria meningitidis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057115590069

Comparison of non-canonical PAMs for CRISPR/Cas9-mediated DNA cleavage in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057115590069

Position-specific chemical modification of siRNAs reduces "off-target" transcript silencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057115590069

Widespread siRNA "off-target" transcript silencing mediated by seed region sequence complementarity

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057115590069

Online GESS: prediction of miRNA-like off-target effects in large-scale RNAi screen data by seed region analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057115590069

siRNA off-target effects in genome-wide screens identify signaling pathway members

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057115590069

Recognizing and avoiding siRNA off-target effects for target identification and therapeutic application

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057115590069

Efficient genome modification by CRISPR-Cas9 nickase with minimal off-target effects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057115590069

Low incidence of off-target mutations in individual CRISPR-Cas9 and TALEN targeted human stem cell clones detected by whole-genome sequencing.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057115590069

High-throughput profiling of off-target DNA cleavage reveals RNA-programmed Cas9 nuclease specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057115590069

CRISPR/Cas9 systems targeting β-globin and CCR5 genes have substantial off-target activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057115590069

High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057115590069

DNA interrogation by the CRISPR RNA-guided endonuclease Cas9.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057115590069

Genome-wide binding of the CRISPR endonuclease Cas9 in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057115590069

Genome-wide analysis reveals characteristics of off-target sites bound by the Cas9 endonuclease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057115590069

RNA-guided editing of bacterial genomes using CRISPR-Cas systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057115590069

Designing functional siRNA with reduced off-target effects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057115590069

Multi-task learning for cross-platform siRNA efficacy prediction: an in-silico study

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057115590069

Improving CRISPR-Cas nuclease specificity using truncated guide RNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057115590069

Sequence-specific inhibition of microRNA via CRISPR/CRISPRi system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057115590069

Automated high-throughput siRNA transfection in raw 264.7 macrophages: a case study for optimization procedure

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057115590069

Quantitative study of electroporation-mediated molecular uptake and cell viability

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057115590069

Nucleoporation of dendritic cells: efficient gene transfer by electroporation into human monocyte-derived dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057115590069

Comparison of the efficiency and safety of non-viral vector-mediated gene transfer into a wide range of human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057115590069

Gene disruption by cell-penetrating peptide-mediated delivery of Cas9 protein and guide RNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057115590069

Cellular siRNA delivery using cell-penetrating peptides modified for endosomal escape

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057115590069

CRISPRseek: a bioconductor package to identify target-specific guide RNAs for CRISPR-Cas9 genome-editing systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057115590069

Advances in genome editing technology and its promising application in evolutionary and ecological studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057115590069

Simultaneous editing of three homoeoalleles in hexaploid bread wheat confers heritable resistance to powdery mildew.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057115590069

Using RNA-seq and targeted nucleases to identify mechanisms of drug resistance in acute myeloid leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057115590069

Parallel chemical genetic and genome-wide RNAi screens identify cytokinesis inhibitors and targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057115590069

An RNAi-based chemical genetic screen identifies three small-molecule inhibitors of the Wnt/wingless signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057115590069

RNA interference: from model organisms towards therapy for neural and neuromuscular disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057115590069

Glial cell line-derived neurotrophic factor and its receptor ret is a novel ligand-receptor complex critical for survival response during podocyte injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057115590069

21 January 2018

Identifiers

DOI

10.1177/1087057115590069

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26048892%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

1 reference