(Q38543385)

4 September 2017

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title

Evolutionary consequences of drug resistance: shared principles across diverse targets and organisms (English)

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4 September 2017

1

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author name string

Dan I Andersson

series ordinal

2

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4 September 2017

7 July 2015

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4 September 2017

Nature Reviews Genetics

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4 September 2017

16

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4 September 2017

8

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4 September 2017

459-471

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https://scigraph.springernature.com/pub.10.1038/nrg3922

4 September 2017

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cites work

Nature, position, and frequency of mutations made in a single cycle of HIV-1 replication

1 reference

Topology of viral evolution

21 January 2018

1 reference

A systematic review of a single-class maintenance strategy with nucleoside/nucleotide reverse transcriptase inhibitors in HIV/AIDS.

21 January 2018

1 reference

Rilpivirine: a new non-nucleoside reverse transcriptase inhibitor

21 January 2018

1 reference

The nucleoside reverse transcriptase inhibitors, nonnucleoside reverse transcriptase inhibitors, and protease inhibitors in the treatment of HIV infections (AIDS).

21 January 2018

1 reference

The dual role of pharmacogenetics in HIV treatment: mutations and polymorphisms regulating antiretroviral drug resistance and disposition.

21 January 2018

1 reference

Development of drug resistance to HIV-1 protease inhibitors

21 January 2018

1 reference

Mutation rate and evolution of fluoroquinolone resistance in Escherichia coli isolates from patients with urinary tract infections.

21 January 2018

1 reference

Gene amplification and adaptive evolution in bacteria.

21 January 2018

1 reference

Contribution of gene amplification to evolution of increased antibiotic resistance in Salmonella typhimurium

21 January 2018

1 reference

Evolution of antifungal-drug resistance: mechanisms and pathogen fitness

21 January 2018

1 reference

The antibiotic resistome: the nexus of chemical and genetic diversity

21 January 2018

1 reference

Origins and evolution of antibiotic resistance

21 January 2018

1 reference

Doomsday postponed? Preventing and reversing epidemics of drug-resistant tuberculosis

21 January 2018

1 reference

The clinical impact of bacterial biofilms

21 January 2018

1 reference

Virulence in malaria: an evolutionary viewpoint

21 January 2018

1 reference

Antimalarial drugs: modes of action and mechanisms of parasite resistance

21 January 2018

1 reference

A plausible mechanism for the antimalarial activity of artemisinin: A computational approach

21 January 2018

1 reference

Malaria: an update on current chemotherapy

21 January 2018

1 reference

The threat of artemisinin-resistant malaria

21 January 2018

1 reference

Evidence of Artemisinin-Resistant Malaria in Western Cambodia

21 January 2018

1 reference

Genetic loci associated with delayed clearance of Plasmodium falciparum following artemisinin treatment in Southeast Asia

21 January 2018

1 reference

A molecular marker of artemisinin-resistant Plasmodium falciparum malaria

21 January 2018

1 reference

Cancer drug resistance: an evolving paradigm

21 January 2018

1 reference

Explaining the high mutation rates of cancer cells to drug and multidrug resistance by chromosome reassortments that are catalyzed by aneuploidy

21 January 2018

1 reference

Chromosomal instability determines taxane response

21 January 2018

1 reference

Drug resistance in cancer: an overview.

21 January 2018

1 reference

The role of tumour-stromal interactions in modifying drug response: challenges and opportunities

21 January 2018

1 reference

Cancer as a dysregulated epigenome allowing cellular growth advantage at the expense of the host

21 January 2018

1 reference

Cancer epigenetics: tumor heterogeneity, plasticity of stem-like states, and drug resistance.

21 January 2018

1 reference

Reduced viral replication capacity of human immunodeficiency virus type 1 subtype C caused by cytotoxic-T-lymphocyte escape mutations in HLA-B57 epitopes of capsid protein

21 January 2018

1 reference

Replicative fitness costs of nonnucleoside reverse transcriptase inhibitor drug resistance mutations on HIV subtype C.

21 January 2018

1 reference

The fitness cost of mutations associated with human immunodeficiency virus type 1 drug resistance is modulated by mutational interactions

21 January 2018

1 reference

Persistence of antibiotic resistance in bacterial populations.

21 January 2018

1 reference

The genetic basis of the fitness costs of antimicrobial resistance: a meta-analysis approach

21 January 2018

1 reference

Fitness cost of chromosomal drug resistance-conferring mutations

21 January 2018

1 reference

Fitness of antibiotic-resistant microorganisms and compensatory mutations.

21 January 2018

1 reference

Fitness trade-offs restrict the evolution of resistance to amphotericin B

21 January 2018

1 reference

The interplay between drug resistance and fitness in malaria parasites

21 January 2018

1 reference

A change of strategy in the war on cancer.

21 January 2018

1 reference

Mutational anatomy of an HIV-1 protease variant conferring cross-resistance to protease inhibitors in clinical trials. Compensatory modulations of binding and activity

21 January 2018

1 reference

Individual contributions of mutant protease and reverse transcriptase to viral infectivity, replication, and protein maturation of antiretroviral drug-resistant human immunodeficiency virus type 1.

21 January 2018

1 reference

Mutations in HIV-1 gag and pol Compensate for the Loss of Viral Fitness Caused by a Highly Mutated Protease

21 January 2018

1 reference

Relative replication fitness of efavirenz-resistant mutants of HIV-1: correlation with frequency during clinical therapy and evidence of compensation for the reduced fitness of K103N + L100I by the nucleoside resistance mutation L74V.

21 January 2018

1 reference

Association of efavirenz hypersusceptibility with virologic response in ACTG 368, a randomized trial of abacavir (ABC) in combination with efavirenz (EFV) and indinavir (IDV) in HIV-infected subjects with prior nucleoside analog experience

21 January 2018

1 reference

Compensation of fitness costs and reversibility of antibiotic resistance mutations

21 January 2018

1 reference

Mutational effects and the evolution of new protein functions.

21 January 2018

1 reference

Novel ribosomal mutations affecting translational accuracy, antibiotic resistance and virulence of Salmonella typhimurium.

21 January 2018

1 reference

Origin of robustness in generating drug-resistant malaria parasites

21 January 2018

1 reference

Tug-of-war between driver and passenger mutations in cancer and other adaptive processes

21 January 2018

1 reference

Within-host bacterial diversity hinders accurate reconstruction of transmission networks from genomic distance data

21 January 2018

1 reference

Evolution of the mutation rate

21 January 2018

1 reference

Methods for determining spontaneous mutation rates

21 January 2018

1 reference

Rates of evolutionary change in viruses: patterns and determinants

21 January 2018

1 reference

Homologous recombination between the tuf genes of Salmonella typhimurium.

21 January 2018

1 reference

21 January 2018

1 reference

An experimental analysis of the curative action of penicillin in acute bacterial infections. III. The effect of suppuration upon the antibacterial action of the drug

21 January 2018

1 reference

Does the cell number 10(9) still really fit one gram of tumor tissue?

21 January 2018

1 reference

Absolute quantification of somatic DNA alterations in human cancer

21 January 2018

1 reference

The biological cost of antibiotic resistance

21 January 2018

1 reference

Long-term dynamics of adaptation in asexual populations

21 January 2018

1 reference

The epidemiology of antibiotic resistance in hospitals: paradoxes and prescriptions

21 January 2018

1 reference

Current perspectives on HIV-1 antiretroviral drug resistance

21 January 2018

1 reference

The distinct contributions of fitness and genetic barrier to the development of antiviral drug resistance

21 January 2018

1 reference

Fitness impaired drug resistant HIV-1 is not compromised in cell-to-cell transmission or establishment of and reactivation from latency

21 January 2018

1 reference

Estimating the fitness advantage conferred by permissive neuraminidase mutations in recent oseltamivir-resistant A(H1N1)pdm09 influenza viruses

21 January 2018

1 reference

Molecular genetic and structural modeling studies of Staphylococcus aureus RNA polymerase and the fitness of rifampin resistance genotypes in relation to clinical prevalence

21 January 2018

1 reference

Comprehensive phenotypic characterization of rifampicin resistance mutations in Salmonella provides insight into the evolution of resistance in Mycobacterium tuberculosis.

21 January 2018

1 reference

Viral fitness cost prevents HIV-1 from evading dolutegravir drug pressure

21 January 2018

1 reference

Selection of resistant bacteria at very low antibiotic concentrations

21 January 2018

1 reference

Selection of resistance at lethal and non-lethal antibiotic concentrations.

21 January 2018

1 reference

Selection of a multidrug resistance plasmid by sublethal levels of antibiotics and heavy metals

21 January 2018

1 reference

Microbiological effects of sublethal levels of antibiotics.

21 January 2018

1 reference

Fitness variations and their impact on the evolution of antiretroviral drug resistance.

21 January 2018

1 reference

Antiviral resistance and impact on viral replication capacity: evolution of viruses under antiviral pressure occurs in three phases

21 January 2018

1 reference

Dynamics of antibiotic resistant Mycobacterium tuberculosis during long-term infection and antibiotic treatment

21 January 2018

1 reference

Helicobacter pylori evolution and phenotypic diversification in a changing host

21 January 2018

1 reference

Environmental heterogeneity drives within-host diversification and evolution of Pseudomonas aeruginosa

21 January 2018

1 reference

The role of clonal interference in the evolutionary dynamics of plasmid-host adaptation

21 January 2018

1 reference

Clonal interference and the evolution of RNA viruses.

21 January 2018

1 reference

Diminishing Returns from Mutation Supply Rate in Asexual Populations

21 January 2018

1 reference

Molecular characterization of clonal interference during adaptive evolution in asexual populations of Saccharomyces cerevisiae

21 January 2018

1 reference

Pervasive genetic hitchhiking and clonal interference in forty evolving yeast populations

21 January 2018

1 reference

Compensatory adaptation to the deleterious effect of antibiotic resistance in Salmonella typhimurium

21 January 2018

1 reference

Fitness-compensatory mutations in rifampicin-resistant RNA polymerase.

21 January 2018

1 reference

Genetic characterization of compensatory evolution in strains carrying rpoB Ser531Leu, the rifampicin resistance mutation most frequently found in clinical isolates.

21 January 2018

1 reference

Biological cost and compensatory evolution in fusidic acid-resistant Staphylococcus aureus

21 January 2018

1 reference

Virulence of antibiotic-resistant Salmonella typhimurium

21 January 2018

1 reference

Evolution and transmission of drug-resistant tuberculosis in a Russian population

21 January 2018

1 reference

Evolutionary pathways of transmitted drug-resistant HIV-1.

21 January 2018

1 reference

HIV-1 reverse transcriptase inhibitor resistance mutations and fitness: a view from the clinic and ex vivo.

21 January 2018

1 reference

Co-evolution of compensatory mutation K43E with mutation M41L in long-term HIV antiretroviral treatment

21 January 2018

1 reference

Empirical fitness landscapes and the predictability of evolution

21 January 2018

1 reference

Emerging viruses: why they are not jacks of all trades?

21 January 2018

1 reference

Topological features of rugged fitness landscapes in sequence space

21 January 2018

1 reference

Biological cost of single and multiple norfloxacin resistance mutations in Escherichia coli implicated in urinary tract infections.

21 January 2018

1 reference

Interplay in the selection of fluoroquinolone resistance and bacterial fitness

21 January 2018

1 reference

Positive epistasis drives the acquisition of multidrug resistance

21 January 2018

1 reference

The cost of antibiotic resistance depends on evolutionary history in Escherichia coli.

21 January 2018

1 reference

Epistasis buffers the fitness effects of rifampicin- resistance mutations in Pseudomonas aeruginosa.

21 January 2018

1 reference

Initial mutations direct alternative pathways of protein evolution

21 January 2018

1 reference

Darwinian evolution can follow only very few mutational paths to fitter proteins

21 January 2018

1 reference

Understanding, predicting and manipulating the genotypic evolution of antibiotic resistance.

21 January 2018

1 reference

Molecular mechanisms of antibacterial multidrug resistance

21 January 2018

1 reference

Multidrug resistance of a porin deletion mutant of Mycobacterium smegmatis

21 January 2018

1 reference

Antibiotic activity against small-colony variants of Staphylococcus aureus: review of in vitro, animal and clinical data

21 January 2018

1 reference

Synergism between beta-lactams and glycopeptides against VanA-type methicillin-resistant Staphylococcus aureus and heterologous expression of the vanA operon

21 January 2018

1 reference

Hyper-susceptibility of a fusidic acid-resistant mutant of Salmonella to different classes of antibiotics.

21 January 2018

1 reference

Alternating antibiotic treatments constrain evolutionary paths to multidrug resistance

21 January 2018

1 reference

Use of collateral sensitivity networks to design drug cycling protocols that avoid resistance development.

21 January 2018

1 reference

Genome-wide analysis captures the determinants of the antibiotic cross-resistance interaction network.

21 January 2018

1 reference

When the most potent combination of antibiotics selects for the greatest bacterial load: the smile-frown transition

21 January 2018

1 reference

Antibiotic interactions that select against resistance.

21 January 2018

1 reference

Accelerated evolution of resistance in multidrug environments

21 January 2018

1 reference

Resistance mutations against dolutegravir in HIV integrase impair the emergence of resistance against reverse transcriptase inhibitors

21 January 2018

1 reference

Viral error catastrophe by mutagenic nucleosides

21 January 2018

1 reference

Perspectives and opportunities for novel antiviral treatments targeting virus fitness

21 January 2018

1 reference

RNA virus error catastrophe: direct molecular test by using ribavirin

21 January 2018

1 reference

The broad-spectrum antiviral ribonucleoside ribavirin is an RNA virus mutagen

21 January 2018

1 reference

Curing of foot-and-mouth disease virus from persistently infected cells by ribavirin involves enhanced mutagenesis.

21 January 2018

1 reference

Human immunodeficiency virus type 1 fitness and tropism: concept, quantification, and clinical relevance.

21 January 2018

1 reference

Lethal mutagenesis of HIV.

21 January 2018

1 reference

A single mutation in poliovirus RNA-dependent RNA polymerase confers resistance to mutagenic nucleotide analogs via increased fidelity

21 January 2018

1 reference

Ribavirin resistance in hepatitis C virus replicon-containing cell lines conferred by changes in the cell line or mutations in the replicon RNA.

21 January 2018

1 reference

Foot-and-mouth disease virus mutant with decreased sensitivity to ribavirin: implications for error catastrophe

21 January 2018

1 reference

Increased fidelity reduces poliovirus fitness and virulence under selective pressure in mice

21 January 2018

1 reference

Counteracting Quasispecies Adaptability: Extinction of a Ribavirin-Resistant Virus Mutant by an Alternative Mutagenic Treatment

21 January 2018

1 reference

Outwitting evolution: fighting drug-resistant TB, malaria, and HIV.

21 January 2018

1 reference

Combination therapies for combating antimicrobial resistance

21 January 2018

1 reference

Combined anticancer therapies: an overview of the latest applications

21 January 2018

1 reference

Fitness Trade-Offs Associated with the Evolution of Resistance to Antifungal Drug Combinations.

21 January 2018

1 reference

Bacterial evolution of antibiotic hypersensitivity.

21 January 2018

1 reference

Whole-genome sequencing of rifampicin-resistant Mycobacterium tuberculosis strains identifies compensatory mutations in RNA polymerase genes.

21 January 2018

1 reference

Challenges of antibacterial discovery

21 January 2018

1 reference

Epidemiology and clinical relevance of microbial resistance determinants versus anti-Gram-positive agents.

21 January 2018

1 reference

HIV molecular epidemiology: transmission and adaptation to human populations

21 January 2018

1 reference

Escape of HIV-1 from a small molecule CCR5 inhibitor is not associated with a fitness loss

21 January 2018

1 reference

Evolvability of an RNA virus is determined by its mutational neighbourhood

21 January 2018

1 reference

Viral quasispecies evolution

21 January 2018

1 reference

Accurate sampling and deep sequencing of the HIV-1 protease gene using a Primer ID

21 January 2018

1 reference

Detection and quantification of rare mutations with massively parallel sequencing

21 January 2018

1 reference

Detection of ultra-rare mutations by next-generation sequencing

21 January 2018

1 reference

Quantitative evolutionary dynamics using high-resolution lineage tracking

21 January 2018

1 reference

A quantitative high-resolution genetic profile rapidly identifies sequence determinants of hepatitis C viral fitness and drug sensitivity

21 January 2018

1 reference

Advances for studying clonal evolution in cancer

21 January 2018

1 reference

The life history of 21 breast cancers

21 January 2018

1 reference

Precise estimates of mutation rate and spectrum in yeast

21 January 2018

1 reference

Mitotic evolution of Plasmodium falciparum shows a stable core genome but recombination in antigen families

21 January 2018

1 reference

Quantitative image analysis of HIV-1 infection in lymphoid tissue.

21 January 2018

1 reference

Nitrofurantoin resistance mechanism and fitness cost in Escherichia coli

21 January 2018

1 reference

Self-regulation of Candida albicans population size during GI colonization

21 January 2018

1 reference

Malaria biology and disease pathogenesis: insights for new treatments

21 January 2018

1 reference

Challenges in circulating tumour cell research

21 January 2018

1 reference

Directed mutagenesis of Mycobacterium smegmatis 16S rRNA to reconstruct the in vivo evolution of aminoglycoside resistance in Mycobacterium tuberculosis

21 January 2018

1 reference

Antibiotic resistance and its cost: is it possible to reverse resistance?

21 January 2018

1 reference

Adaptation to the fitness costs of antibiotic resistance in Escherichia coli

31 March 2020

1 reference

Targeting Notch, Hedgehog, and Wnt pathways in cancer stem cells: clinical update

31 March 2020

1 reference

The fate of competing beneficial mutations in an asexual population.

31 March 2020

1 reference

Towards an integrated model of bacterial conjugation

31 March 2020

1 reference

12 December 2020

Lower in vivo mutation rate of human immunodeficiency virus type 1 than that predicted from the fidelity of purified reverse transcriptase

1 reference

12 December 2020

Compensatory evolution in rifampin-resistant Escherichia coli

1 reference

12 December 2020

Compensatory mutations, antibiotic resistance and the population genetics of adaptive evolution in bacteria

1 reference

12 December 2020

Rates of spontaneous mutation

1 reference

12 December 2020

Drug resistance during indinavir therapy is caused by mutations in the protease gene and in its Gag substrate cleavage sites

1 reference

12 December 2020

Antiretroviral treatment of adult HIV infection: 2012 recommendations of the International Antiviral Society-USA panel.

1 reference

12 December 2020

Evolutionary reversals of antibiotic resistance in experimental populations of Pseudomonas aeruginosa.

1 reference

12 December 2020

Genetic studies on microbial cross resistance to toxic agents. I. Cross resistance of Escherichia coli to fifteen antibiotics

1 reference

12 December 2020

Identifiers

DOI

10.1038/NRG3922

1 reference

PubMed ID

26149714

Dimensions Publication ID

4 September 2017

0 references

1 reference

PubMed ID

26149714