(Q38588878)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26383138%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

title

MYC: connecting selective transcriptional control to global RNA production (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26383138%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26383138%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

Bruno Amati

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26383138%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

author name string

Theresia R Kress

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26383138%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

language of work or name

English

0 references

publication date

18 September 2015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26383138%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

published in

Nature Reviews Cancer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26383138%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

volume

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26383138%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

issue

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26383138%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

page(s)

593-607

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26383138%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/nrc3984

24 February 2020

exact match

0 references

cites work

Activation of a cellular onc gene by promoter insertion in ALV-induced lymphoid leukosis

1 reference

myc function and regulation

31 March 2020

1 reference

The c-myc promoter: still MysterY and challenge

31 March 2020

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31 March 2020

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Mammalian MYC Proteins and Cancer

31 March 2020

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Myc function in Drosophila.

31 March 2020

1 reference

Drosophila Myc: A master regulator of cellular performance

31 March 2020

1 reference

Premetazoan ancestry of the Myc-Max network

31 March 2020

1 reference

Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes

31 March 2020

1 reference

MYC activation is a hallmark of cancer initiation and maintenance

31 March 2020

1 reference

Reflecting on 25 years with MYC.

31 March 2020

1 reference

Emerging landscape of oncogenic signatures across human cancers

31 March 2020

1 reference

The Myc oncoprotein as a therapeutic target for human cancer

31 March 2020

1 reference

Conditional transgenic models define how MYC initiates and maintains tumorigenesis

31 March 2020

1 reference

MYC inactivation uncovers pluripotent differentiation and tumour dormancy in hepatocellular cancer

31 March 2020

1 reference

Reversible tumorigenesis by MYC in hematopoietic lineages

31 March 2020

1 reference

Sustained loss of a neoplastic phenotype by brief inactivation of MYC

31 March 2020

1 reference

Suppression of Myc-induced apoptosis in beta cells exposes multiple oncogenic properties of Myc and triggers carcinogenic progression.

31 March 2020

1 reference

Modelling Myc inhibition as a cancer therapy

31 March 2020

1 reference

Endogenous Myc maintains the tumor microenvironment

31 March 2020

1 reference

Max: a helix-loop-helix zipper protein that forms a sequence-specific DNA-binding complex with Myc

31 March 2020

1 reference

Transcriptional amplification in tumor cells with elevated c-Myc.

31 March 2020

1 reference

c-Myc is a universal amplifier of expressed genes in lymphocytes and embryonic stem cells

31 March 2020

1 reference

Selective transcriptional regulation by Myc in cellular growth control and lymphomagenesis.

31 March 2020

1 reference

Activation and repression by oncogenic MYC shape tumour-specific gene expression profiles.

31 March 2020

1 reference

Genomic targets of the human c-Myc protein

31 March 2020

1 reference

Global mapping of c-Myc binding sites and target gene networks in human B cells

31 March 2020

1 reference

CpG islands and the regulation of transcription

31 March 2020

1 reference

Myc-binding-site recognition in the human genome is determined by chromatin context

31 March 2020

1 reference

An extended transcriptional network for pluripotency of embryonic stem cells

31 March 2020

1 reference

Facilitators and impediments of the pluripotency reprogramming factors' initial engagement with the genome

31 March 2020

1 reference

Pioneer transcription factors target partial DNA motifs on nucleosomes to initiate reprogramming

31 March 2020

1 reference

Gene regulation and epigenetic remodeling in murine embryonic stem cells by c-Myc

31 March 2020

1 reference

Cell-type specific and combinatorial usage of diverse transcription factors revealed by genome-wide binding studies in multiple human cells

31 March 2020

1 reference

Genome recognition by MYC.

31 March 2020

1 reference

Genomic binding by the Drosophila Myc, Max, Mad/Mnt transcription factor network

31 March 2020

1 reference

Sequence specificity incompletely defines the genome-wide occupancy of Myc.

31 March 2020

1 reference

X-ray structures of Myc-Max and Mad-Max recognizing DNA. Molecular bases of regulation by proto-oncogenic transcription factors

31 March 2020

1 reference

The mechanism of discrimination between cognate and non-specific DNA by dimeric b/HLH/LZ transcription factors

31 March 2020

1 reference

Interaction with WDR5 promotes target gene recognition and tumorigenesis by MYC

31 March 2020

1 reference

The chromodomain-containing histone acetyltransferase TIP60 acts as a code reader, recognizing the epigenetic codes for initiating transcription

31 March 2020

1 reference

MYC recruits the TIP60 histone acetyltransferase complex to chromatin

31 March 2020

1 reference

Genome-wide mapping of Myc binding and gene regulation in serum-stimulated fibroblasts.

31 March 2020

1 reference

An expansive human regulatory lexicon encoded in transcription factor footprints

31 March 2020

1 reference

Sequence features and chromatin structure around the genomic regions bound by 119 human transcription factors

31 March 2020

1 reference

Transcriptional repression: the dark side of myc.

31 March 2020

1 reference

TGFbeta influences Myc, Miz-1 and Smad to control the CDK inhibitor p15INK4b

31 March 2020

1 reference

Repression of p15INK4b expression by Myc through association with Miz-1

31 March 2020

1 reference

Repression of SRF target genes is critical for Myc-dependent apoptosis of epithelial cells

31 March 2020

1 reference

Kinetic profiling of the c-Myc transcriptome and bioinformatic analysis of repressed gene promoters

31 March 2020

1 reference

Analysis of Myc bound loci identified by CpG island arrays shows that Max is essential for Myc-dependent repression

31 March 2020

1 reference

Transcriptional regulation and transformation by Myc proteins

31 March 2020

1 reference

Determination of copy number of c-Myc protein per cell by quantitative Western blotting

31 March 2020

1 reference

Myc requires distinct E2F activities to induce S phase and apoptosis

31 March 2020

1 reference

Myc regulates the transcription of the PRC2 gene to control the expression of developmental genes in embryonic stem cells

31 March 2020

1 reference

c-Myc-induced transcription factor AP4 is required for host protection mediated by CD8+ T cells

31 March 2020

1 reference

A positive role for Myc in TGFbeta-induced Snail transcription and epithelial-to-mesenchymal transition

31 March 2020

1 reference

Myc influences global chromatin structure.

31 March 2020

1 reference

MicroRNAs as regulators and mediators of c-MYC function

31 March 2020

1 reference

MYC acts via the PTEN tumor suppressor to elicit autoregulation and genome-wide gene repression by activation of the Ezh2 methyltransferase

31 March 2020

1 reference

Combinatorial analysis of transcription factor partners reveals recruitment of c-MYC to estrogen receptor-alpha responsive promoters.

31 March 2020

1 reference

Cell-type independent MYC target genes reveal a primordial signature involved in biomass accumulation

31 March 2020

1 reference

MYC, metabolism, cell growth, and tumorigenesis.

31 March 2020

1 reference

Taming of the beast: shaping Myc-dependent amplification

31 March 2020

1 reference

c-Myc regulates transcriptional pause release

31 March 2020

1 reference

The Myc transactivation domain promotes global phosphorylation of the RNA polymerase II carboxy-terminal domain independently of direct DNA binding

31 March 2020

1 reference

Cellular MYCro economics: Balancing MYC function with MYC expression

31 March 2020

1 reference

Protein and nucleotide biosynthesis are coupled by a single rate-limiting enzyme, PRPS2, to drive cancer

31 March 2020

1 reference

Coordinating genome expression with cell size

31 March 2020

1 reference

Connecting variability in global transcription rate to mitochondrial variability

31 March 2020

1 reference

Single mammalian cells compensate for differences in cellular volume and DNA copy number through independent global transcriptional mechanisms.

31 March 2020

1 reference

New cell cycle compartments identified by multiparameter flow cytometry

31 March 2020

1 reference

CDK7 inhibition suppresses super-enhancer-linked oncogenic transcription in MYCN-driven cancer.

31 March 2020

1 reference

MYC regulates the non-coding transcriptome.

31 March 2020

1 reference

Revisiting global gene expression analysis

31 March 2020

1 reference

Myc and its interactors take shape.

31 March 2020

1 reference

c-Myc associates with ribosomal DNA and activates RNA polymerase I transcription.

31 March 2020

1 reference

c-Myc binds to human ribosomal DNA and stimulates transcription of rRNA genes by RNA polymerase I

31 March 2020

1 reference

Direct activation of RNA polymerase III transcription by c-Myc

31 March 2020

1 reference

Control of transcriptional elongation

31 March 2020

1 reference

Myc recruits P-TEFb to mediate the final step in the transcriptional activation of the cad promoter

31 March 2020

1 reference

c-Myc recruits P-TEFb for transcription, cellular proliferation and apoptosis

31 March 2020

1 reference

Myc-induced proliferation and transformation require Akt-mediated phosphorylation of FoxO proteins

31 March 2020

1 reference

P-TEFb is a crucial co-factor for Myc transactivation.

31 March 2020

1 reference

RNA polymerase stalling at developmental control genes in the Drosophila melanogaster embryo

31 March 2020

1 reference

Promoter-proximal pausing of RNA polymerase II: emerging roles in metazoans

31 March 2020

1 reference

Getting up to speed with transcription elongation by RNA polymerase II

31 March 2020

1 reference

Large-scale identification of c-MYC-associated proteins using a combined TAP/MudPIT approach

31 March 2020

1 reference

Chromatin connectivity maps reveal dynamic promoter-enhancer long-range associations

31 March 2020

1 reference

The pluripotent regulatory circuitry connecting promoters to their long-range interacting elements.

31 March 2020

1 reference

MYC on the path to cancer

31 March 2020

1 reference

MYC as a regulator of ribosome biogenesis and protein synthesis

31 March 2020

1 reference

Myc-dependent regulation of ribosomal RNA synthesis during Drosophila development.

31 March 2020

1 reference

MAD1 and c-MYC regulate UBF and rDNA transcription during granulocyte differentiation

31 March 2020

1 reference

An essential E box in the promoter of the gene encoding the mRNA cap-binding protein (eukaryotic initiation factor 4E) is a target for activation by c-myc

31 March 2020

1 reference

Increased expression of eukaryotic translation initiation factors eIF-4E and eIF-2 alpha in response to growth induction by c-myc

31 March 2020

1 reference

c-Myc enhances protein synthesis and cell size during B lymphocyte development

31 March 2020

1 reference

Control of cell growth by c-Myc in the absence of cell division

31 March 2020

1 reference

Drosophila myc regulates cellular growth during development.

31 March 2020

1 reference

Suppression of Myc oncogenic activity by ribosomal protein haploinsufficiency

31 March 2020

1 reference

Eukaryotic initiation factor 6 is rate-limiting in translation, growth and transformation

31 March 2020

1 reference

S-adenosyl homocysteine hydrolase is required for Myc-induced mRNA cap methylation, protein synthesis, and cell proliferation.

31 March 2020

1 reference

Specific regulation of mRNA cap methylation by the c-Myc and E2F1 transcription factors

31 March 2020

1 reference

Global regulation of nucleotide biosynthetic genes by c-Myc

31 March 2020

1 reference

The transcription factor Myc controls metabolic reprogramming upon T lymphocyte activation

31 March 2020

1 reference

An E-box-mediated increase in cad transcription at the G1/S-phase boundary is suppressed by inhibitory c-Myc mutants

31 March 2020

1 reference

A functional screen for Myc-responsive genes reveals serine hydroxymethyltransferase, a major source of the one-carbon unit for cell metabolism

31 March 2020

1 reference

Myc stimulates nuclearly encoded mitochondrial genes and mitochondrial biogenesis

31 March 2020

1 reference

Acetyl-CoA induces cell growth and proliferation by promoting the acetylation of histones at growth genes.

31 March 2020

1 reference

Myc-dependent mitochondrial generation of acetyl-CoA contributes to fatty acid biosynthesis and histone acetylation during cell cycle entry

31 March 2020

1 reference

Metabolic regulation of epigenetics

31 March 2020

1 reference

CDK9-mediated transcription elongation is required for MYC addiction in hepatocellular carcinoma

31 March 2020

1 reference

Deep sequencing of subcellular RNA fractions shows splicing to be predominantly co-transcriptional in the human genome but inefficient for lncRNAs

31 March 2020

1 reference

Context-dependent control of alternative splicing by RNA-binding proteins

31 March 2020

1 reference

Considering the kinetics of mRNA synthesis in the analysis of the genome and epigenome reveals determinants of co-transcriptional splicing.

31 March 2020

1 reference

Genome-wide RNAi screens in human brain tumor isolates reveal a novel viability requirement for PHF5A

31 March 2020

1 reference

MYC regulates the core pre-mRNA splicing machinery as an essential step in lymphomagenesis

31 March 2020

1 reference

The spliceosome is a therapeutic vulnerability in MYC-driven cancer

31 March 2020

1 reference

The splicing factor SRSF1 regulates apoptosis and proliferation to promote mammary epithelial cell transformation

31 March 2020

1 reference

Oncogenic splicing factor SRSF1 is a critical transcriptional target of MYC.

31 March 2020

1 reference

HnRNP proteins controlled by c-Myc deregulate pyruvate kinase mRNA splicing in cancer

31 March 2020

1 reference

Myc and SAGA rewire an alternative splicing network during early somatic cell reprogramming

31 March 2020

1 reference

SNIP1 is a candidate modifier of the transcriptional activity of c-Myc on E box-dependent target genes

31 March 2020

1 reference

Regulation of cyclin D1 RNA stability by SNIP1

31 March 2020

1 reference

Tristetraprolin impairs myc-induced lymphoma and abolishes the malignant state

31 March 2020

1 reference

AREsite: a database for the comprehensive investigation of AU-rich elements

31 March 2020

1 reference

Global target mRNA specification and regulation by the RNA-binding protein ZFP36.

31 March 2020

1 reference

The many pathways of RNA degradation

31 March 2020

1 reference

Nonsense-mediated mRNA decay - mechanisms of substrate mRNA recognition and degradation in mammalian cells

31 March 2020

1 reference

Overexpression of the c-myc oncogene inhibits nonsense-mediated RNA decay in B lymphocytes

31 March 2020

1 reference

The eukaryotic RNA exosome

31 March 2020

1 reference

Deregulated Myc requires MondoA/Mlx for metabolic reprogramming and tumorigenesis

31 March 2020

1 reference

Myc represses the p21(WAF1/CIP1) promoter and interacts with Sp1/Sp3.

31 March 2020

1 reference

Direct interaction of c-Myc with Smad2 and Smad3 to inhibit TGF-beta-mediated induction of the CDK inhibitor p15(Ink4B)

31 March 2020

1 reference

Inhibition of transcriptional regulator Yin-Yang-1 by association with c-Myc

31 March 2020

1 reference

Myc represses transcription through recruitment of DNA methyltransferase corepressor

31 March 2020

1 reference

Miz1 is required to maintain autophagic flux.

31 March 2020

1 reference

Miz-1 activates gene expression via a novel consensus DNA binding motif

31 March 2020

1 reference

Repression of transcription of the p27(Kip1) cyclin-dependent kinase inhibitor gene by c-Myc.

31 March 2020

1 reference

Negative regulation of the mammalian UV response by Myc through association with Miz-1

31 March 2020

1 reference

Myc downregulation by transforming growth factor beta required for activation of the p15(Ink4b) G(1) arrest pathway.

31 March 2020

1 reference

The interaction between Myc and Miz1 is required to antagonize TGFbeta-dependent autocrine signaling during lymphoma formation and maintenance

31 March 2020

1 reference

Myc regulates keratinocyte adhesion and differentiation via complex formation with Miz1

31 March 2020

1 reference

c-Myc controls the balance between hematopoietic stem cell self-renewal and differentiation

31 March 2020

1 reference

The c-myc oncogene perturbs B lymphocyte development in Eμ-myc transgenic mice

31 March 2020

2 references

31 March 2020

12 December 2020

Inhibition of cell differentiation: a critical mechanism for MYC-mediated carcinogenesis?

1 reference

Reversible kinetic analysis of Myc targets in vivo provides novel insights into Myc-mediated tumorigenesis.

31 March 2020

1 reference

NOTCH1 directly regulates c-MYC and activates a feed-forward-loop transcriptional network promoting leukemic cell growth

31 March 2020

1 reference

Notch1 contributes to mouse T-cell leukemia by directly inducing the expression of c-myc

31 March 2020

1 reference

c-Myc is an important direct target of Notch1 in T-cell acute lymphoblastic leukemia/lymphoma

31 March 2020

1 reference

Myc deletion rescues Apc deficiency in the small intestine

31 March 2020

1 reference

Identification of c-MYC as a target of the APC pathway

31 March 2020

1 reference

Medulloblastoma growth inhibition by hedgehog pathway blockade

31 March 2020

1 reference

Dysregulation of the Hedgehog pathway in human hepatocarcinogenesis

31 March 2020

1 reference

31 March 2020

1 reference

STAT3 is required for the gp130-mediated full activation of the c-myc gene

31 March 2020

1 reference

E2F4/5 and p107 as Smad cofactors linking the TGFbeta receptor to c-myc repression

31 March 2020

1 reference

Transforming growth factor beta-mediated transcriptional repression of c-myc is dependent on direct binding of Smad3 to a novel repressive Smad binding element

31 March 2020

1 reference

The mTORC1/S6K1 pathway regulates glutamine metabolism through the eIF4B-dependent control of c-Myc translation

31 March 2020

1 reference

Translational control of c-MYC by rapamycin promotes terminal myeloid differentiation

31 March 2020

1 reference

A MAPK/HNRPK pathway controls BCR/ABL oncogenic potential by regulating MYC mRNA translation

31 March 2020

1 reference

The MK5/PRAK kinase and Myc form a negative feedback loop that is disrupted during colorectal tumorigenesis

31 March 2020

1 reference

Ras enhances Myc protein stability.

31 March 2020

1 reference

Multiple Ras-dependent phosphorylation pathways regulate Myc protein stability.

31 March 2020

1 reference

Feedback regulation of c-Myc by ribosomal protein L11

31 March 2020

1 reference

Induction of ribosomal genes and hepatocyte hypertrophy by adenovirus-mediated expression of c-Myc in vivo

31 March 2020

1 reference

Cyclins D1 and D2 mediate myc-induced proliferation via sequestration of p27(Kip1) and p21(Cip1).

31 March 2020

1 reference

Ras and Myc can drive oncogenic cell proliferation through individual D-cyclins.

31 March 2020

1 reference

Induction of cyclin E-cdk2 kinase activity, E2F-dependent transcription and cell growth by Myc are genetically separable events

31 March 2020

1 reference

Myc activation of cyclin E/Cdk2 kinase involves induction of cyclin E gene transcription and inhibition of p27(Kip1) binding to newly formed complexes

31 March 2020

1 reference

Tumor cell-selective regulation of NOXA by c-MYC in response to proteasome inhibition.

31 March 2020

1 reference

Bim is a suppressor of Myc-induced mouse B cell leukemia

31 March 2020

1 reference

Evasion of the p53 tumour surveillance network by tumour-derived MYC mutants

31 March 2020

1 reference

Apoptosis triggered by Myc-induced suppression of Bcl-X(L) or Bcl-2 is bypassed during lymphomagenesis

31 March 2020

1 reference

c-Myc Augments Gamma Irradiation-Induced Apoptosis by Suppressing Bcl-XL

31 March 2020

1 reference

Hypoxia-inducible factor 1 and dysregulated c-Myc cooperatively induce vascular endothelial growth factor and metabolic switches hexokinase 2 and pyruvate dehydrogenase kinase 1

31 March 2020

1 reference

c-Myc transactivation of LDH-A: implications for tumor metabolism and growth

31 March 2020

1 reference

Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction

31 March 2020

1 reference

c-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism

31 March 2020

1 reference

HIF-1 inhibits mitochondrial biogenesis and cellular respiration in VHL-deficient renal cell carcinoma by repression of C-MYC activity

31 March 2020

1 reference

Mitochondrial p32 is upregulated in Myc expressing brain cancers and mediates glutamine addiction

31 March 2020

1 reference

An integrated database of genes responsive to the Myc oncogenic transcription factor: identification of direct genomic targets

31 March 2020

1 reference

Transcriptional control of DNA replication licensing by Myc.

31 March 2020

1 reference

Non-transcriptional control of DNA replication by c-Myc

31 March 2020

1 reference

C-MYC transcriptionally amplifies SOX2 target genes to regulate self-renewal in multipotent otic progenitor cells

31 March 2020

1 reference

c-MYC-miRNA circuitry: a central regulator of aggressive B-cell malignancies

31 March 2020

1 reference

Widespread microRNA repression by Myc contributes to tumorigenesis

31 March 2020

1 reference

Deep sequencing of MYC DNA-binding sites in Burkitt lymphoma

31 March 2020

1 reference

Isolation and characterization of c-myc, a cellular homolog of the oncogene (v-myc) of avian myelocytomatosis virus strain 29

31 March 2020

1 reference

12 December 2020

Immunologic competence of B cells subjected to constitutive c-myc oncogene expression in immunoglobulin heavy chain enhancer myc transgenic mice

1 reference

12 December 2020

Association of Myc with the zinc-finger protein Miz-1 defines a novel pathway for gene regulation by Myc

1 reference

12 December 2020

c-myc protein expression in untransformed fibroblasts

1 reference

12 December 2020

c-MYC-induced genomic instability.

1 reference

12 December 2020

Mechanism for the transcriptional repression by c-Myc on PDGF beta-receptor

1 reference

12 December 2020

mRNAs containing extensive secondary structure in their 5' non-coding region translate efficiently in cells overexpressing initiation factor eIF-4E

1 reference

12 December 2020

Bax is a transcriptional target and mediator of c-myc-induced apoptosis.

1 reference

12 December 2020

MYC-repressed long noncoding RNAs antagonize MYC-induced cell proliferation and cell cycle progression

1 reference

12 December 2020