(Q38592859)

4 September 2017

title

From Genomics to Gene Therapy: Induced Pluripotent Stem Cells Meet Genome Editing (English)

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4 September 2017

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2

Shinya Yamanaka

1 reference

4 September 2017

Akitsu Hotta

1

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language of work or name

1 reference

25 September 2015

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Annual Review of Genetics

4 September 2017

published in

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4 September 2017

volume

49

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4 September 2017

page(s)

47-70

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Induction of pluripotent stem cells from adult human fibroblasts by defined factors

4 September 2017

cites work

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Targeted gene correction of α1-antitrypsin deficiency in induced pluripotent stem cells

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11 October 2022

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11 October 2022

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11 October 2022

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11 October 2022

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Site-specific gene correction of a point mutation in human iPS cells derived from an adult patient with sickle cell disease

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

Efficient TALEN construction and evaluation methods for human cell and animal applications.

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

Precise gene modification mediated by TALEN and single-stranded oligodeoxynucleotides in human cells

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11 October 2022

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Engineering complex synthetic transcriptional programs with CRISPR RNA scaffolds

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11 October 2022

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Human hepatocytes with drug metabolic function induced from fibroblasts by lineage reprogramming.

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11 October 2022

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Formation of pluripotent stem cells in the mammalian embryo depends on the POU transcription factor Oct4

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11 October 2022

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Seamless modification of wild-type induced pluripotent stem cells to the natural CCR5Δ32 mutation confers resistance to HIV infection

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

The length of homology required for gene targeting in embryonic stem cells

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

Correction of sickle cell disease by homologous recombination in embryonic stem cells

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

Murine embryonic stem cell differentiation is promoted by SOCS-3 and inhibited by the zinc finger transcription factor Klf4

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

Development of zinc finger domains for recognition of the 5'-ANN-3' family of DNA sequences and their use in the construction of artificial transcription factors

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

Delivery of full-length factor VIII using a piggyBac transposon vector to correct a mouse model of hemophilia A.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

Efficient drug screening and gene correction for treating liver disease using patient-specific stem cells

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

Targeted genome editing tools for disease modeling and gene therapy

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

Nuclear reprogramming of somatic cells after fusion with human embryonic stem cells

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

Breaking the code of DNA binding specificity of TAL-type III effectors

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

New frontier in regenerative medicine: site-specific gene correction in patient-specific induced pluripotent stem cells

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

A simple cipher governs DNA recognition by TAL effectors

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

A TALEN genome-editing system for generating human stem cell-based disease models

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

Efficient targeting of expressed and silent genes in human ESCs and iPSCs using zinc-finger nucleases

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

CRISPR RNA-guided activation of endogenous human genes

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

Genome-wide detection of DNA double-stranded breaks induced by engineered nucleases.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

Treatment of sickle cell anemia mouse model with iPS cells generated from autologous skin

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

Pathways disrupted in human ALS motor neurons identified through genetic correction of mutant SOD1.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

Toward controlling gene expression at will: selection and design of zinc finger domains recognizing each of the 5'-GNN-3' DNA target sequences

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

RNA-guided human genome engineering via Cas9

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

Multipotent cell lineages in early mouse development depend on SOX2 function

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

Homologous recombination in human embryonic stem cells.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

One-step generation of mice carrying reporter and conditional alleles by CRISPR/Cas-mediated genome engineering

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

A cut above the rest: targeted genome editing technologies in human pluripotent stem cells

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

In vivo selection of engineered homing endonucleases using double-strand break induced homologous recombination

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

Double nicking by RNA-guided CRISPR Cas9 for enhanced genome editing specificity

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

Targeting DNA double-strand breaks with TAL effector nucleases

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

Precise correction of the dystrophin gene in duchenne muscular dystrophy patient induced pluripotent stem cells by TALEN and CRISPR-Cas9.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

New cell lines from mouse epiblast share defining features with human embryonic stem cells

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

A murine ESC-like state facilitates transgenesis and homologous recombination in human pluripotent stem cells.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

DNA-binding specificity is a major determinant of the activity and toxicity of zinc-finger nucleases

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

Engineering of human pluripotent stem cells by AAV-mediated gene targeting

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

RNA-programmed genome editing in human cells

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

Nuclear reprogramming of somatic cells by in vitro hybridization with ES cells.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

20 years of gene therapy for SCID.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

A guide to genome engineering with programmable nucleases

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

Efficient and accurate homologous recombination in hESCs and hiPSCs using helper-dependent adenoviral vectors

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

CRISPR-mediated modular RNA-guided regulation of transcription in eukaryotes

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

Reading frame correction by targeted genome editing restores dystrophin expression in cells from Duchenne muscular dystrophy patients.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

Zinc finger nucleases: looking toward translation.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

Human zinc fingers as building blocks in the construction of artificial transcription factors.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

Highly efficient endogenous human gene correction using designed zinc-finger nucleases

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

DNA targeting specificity of RNA-guided Cas9 nucleases

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

Zinc-finger nuclease-mediated correction of α-thalassemia in iPS cells

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

ZFN, TALEN, and CRISPR/Cas-based methods for genome engineering

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

An iCRISPR platform for rapid, multiplexable, and inducible genome editing in human pluripotent stem cells

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

Generation of isogenic pluripotent stem cells differing exclusively at two early onset Parkinson point mutations

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

Human hematopoietic stem/progenitor cells modified by zinc-finger nucleases targeted to CCR5 control HIV-1 in vivo

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

Isolation of human iPS cells using EOS lentiviral vectors to select for pluripotency

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

Systematic identification of culture conditions for induction and maintenance of naive human pluripotency

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

Functional genomics, proteomics, and regulatory DNA analysis in isogenic settings using zinc finger nuclease-driven transgenesis into a safe harbor locus in the human genome

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

Design and selection of novel Cys2His2 zinc finger proteins

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

A CRISPR/Cas9-based system for reprogramming cell lineage specification.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

Enhanced efficiency of human pluripotent stem cell genome editing through replacing TALENs with CRISPRs

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

Monitoring and robust induction of nephrogenic intermediate mesoderm from human pluripotent stem cells

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

Pancreatic endoderm derived from human embryonic stem cells generates glucose-responsive insulin-secreting cells in vivo

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

Targeted chromosomal gene modification in human cells by single-stranded oligodeoxynucleotides in the presence of a DNA double-strand break

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

Core transcriptional regulatory circuitry in human embryonic stem cells

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

A ROCK inhibitor permits survival of dissociated human embryonic stem cells

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

Targeted gene therapy and cell reprogramming in Fanconi anemia

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

Embryonic stem cell trials for macular degeneration: a preliminary report

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

Translating dosage compensation to trisomy 21

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

Targeted and genome-wide sequencing reveal single nucleotide variations impacting specificity of Cas9 in human stem cells

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

Isolation of single-base genome-edited human iPS cells without antibiotic selection

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

Microhomology-based choice of Cas9 nuclease target sites.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

Derivation of pluripotent epiblast stem cells from mammalian embryos

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

Low incidence of off-target mutations in individual CRISPR-Cas9 and TALEN targeted human stem cell clones detected by whole-genome sequencing.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

RNA-guided gene activation by CRISPR-Cas9-based transcription factors

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

Gene targeting in a HUES line of human embryonic stem cells via electroporation

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

A novel engineered meganuclease induces homologous recombination in yeast and mammalian cells

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

BBS mutations modify phenotypic expression of CEP290-related ciliopathies

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

Optimization of scarless human stem cell genome editing

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

Demarcation of stable subpopulations within the pluripotent hESC compartment

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

Modeling for Lesch-Nyhan disease by gene targeting in human embryonic stem cells

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

Efficient clinical scale gene modification via zinc finger nuclease-targeted disruption of the HIV co-receptor CCR5

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

Targeted chromosomal duplications and inversions in the human genome using zinc finger nucleases

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

SnapShot: directed differentiation of pluripotent stem cells

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

Introduction of double-strand breaks into the genome of mouse cells by expression of a rare-cutting endonuclease

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

Expression of a site-specific endonuclease stimulates homologous recombination in mammalian cells

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

iPS cells: a game changer for future medicine

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

Development and applications of CRISPR-Cas9 for genome engineering

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

m(6)A RNA modification controls cell fate transition in mammalian embryonic stem cells

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

Oxidase-deficient neutrophils from X-linked chronic granulomatous disease iPS cells: functional correction by zinc finger nuclease-mediated safe harbor targeting

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

Highly efficient transient gene expression and gene targeting in primate embryonic stem cells with helper-dependent adenoviral vectors

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

Multiplexed activation of endogenous genes by CRISPR-on, an RNA-guided transcriptional activator system

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

Gene editing of CCR5 in autologous CD4 T cells of persons infected with HIV

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

Generation of an ICF syndrome model by efficient genome editing of human induced pluripotent stem cells using the CRISPR system

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

Seamless gene correction of β-thalassemia mutations in patient-specific iPSCs using CRISPR/Cas9 and piggyBac

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

Gene targeting in mice: functional analysis of the mammalian genome for the twenty-first century

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

Role of ERas in promoting tumour-like properties in mouse embryonic stem cells

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

TALEN-based gene correction for epidermolysis bullosa.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

LIF/STAT3 controls ES cell self-renewal and pluripotency by a Myc-dependent mechanism.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

Establishment of HIV-1 resistance in CD4+ T cells by genome editing using zinc-finger nucleases

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

A protein-tagging system for signal amplification in gene expression and fluorescence imaging

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

Ribosomal and hematopoietic defects in induced pluripotent stem cells derived from Diamond Blackfan anemia patients.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

Functional expression cloning of Nanog, a pluripotency sustaining factor in embryonic stem cells

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

Genetic engineering of human pluripotent cells using TALE nucleases

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

Generation of redesigned homing endonucleases comprising DNA-binding domains derived from two different scaffolds

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

High-frequency genome editing using ssDNA oligonucleotides with zinc-finger nucleases

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

Viable offspring derived from fetal and adult mammalian cells

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

Derivation of novel human ground state naive pluripotent stem cells

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

CRISPR-Cas systems for editing, regulating and targeting genomes

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

Deterministic direct reprogramming of somatic cells to pluripotency

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

Disruption of the proto-oncogene int-2 in mouse embryo-derived stem cells: a general strategy for targeting mutations to non-selectable genes

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

Targeted genome editing in human cells with zinc finger nucleases constructed via modular assembly

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

Multi-kilobase homozygous targeted gene replacement in human induced pluripotent stem cells

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

Sexually mature individuals of Xenopus laevis from the transplantation of single somatic nuclei

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

Transcription activator-like effector nuclease (TALEN)-mediated gene correction in integration-free β-thalassemia induced pluripotent stem cells

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

Induction of homologous recombination in mammalian chromosomes by using the I-SceI system of Saccharomyces cerevisiae

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

Targeted gene correction minimally impacts whole-genome mutational load in human-disease-specific induced pluripotent stem cell clones.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

Gene targeting of a disease-related gene in human induced pluripotent stem and embryonic stem cells

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

Whole-genome sequencing analysis reveals high specificity of CRISPR/Cas9 and TALEN-based genome editing in human iPSCs

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

Requirements for double-strand cleavage by chimeric restriction enzymes with zinc finger DNA-recognition domains

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

Differential roles for Sox15 and Sox2 in transcriptional control in mouse embryonic stem cells

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

Isolation of rare recombinants without using selectable markers for one-step seamless BAC mutagenesis.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

A TALE nuclease architecture for efficient genome editing

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

Modeling disease in human ESCs using an efficient BAC-based homologous recombination system

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

Targeted inversion and reversion of the blood coagulation factor 8 gene in human iPS cells using TALENs

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

Insertion of DNA sequences into the human chromosomal beta-globin locus by homologous recombination

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

Resetting transcription factor control circuitry toward ground-state pluripotency in human

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

Repurposing CRISPR as an RNA-guided platform for sequence-specific control of gene expression

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

Genetic and chemical correction of cholesterol accumulation and impaired autophagy in hepatic and neural cells derived from Niemann-Pick Type C patient-specific iPS cells.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

Genetic correction using engineered nucleases for gene therapy applications

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

Genome editing with engineered zinc finger nucleases

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

In situ genetic correction of the sickle cell anemia mutation in human induced pluripotent stem cells using engineered zinc finger nucleases

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

An AAVS1-targeted minigene platform for correction of iPSCs from all five types of chronic granulomatous disease

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

Human intestinal tissue with adult stem cell properties derived from pluripotent stem cells

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

Generation of CD34+ cells from CCR5-disrupted human embryonic and induced pluripotent stem cells

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

Naive and primed pluripotent states

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

Gene editing in human stem cells using zinc finger nucleases and integrase-defective lentiviral vector delivery

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

One-step generation of mice carrying mutations in multiple genes by CRISPR/Cas-mediated genome engineering

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

Comprehensive DNA recognition through concerted interactions from adjacent zinc fingers

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

DICE, an efficient system for iterative genomic editing in human pluripotent stem cells

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

Characterization of human induced pluripotent stem cell-derived retinal pigment epithelium cell sheets aiming for clinical application.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

Generation of the SCN1A epilepsy mutation in hiPS cells using the TALEN technique

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

Genetic correction of tauopathy phenotypes in neurons derived from human induced pluripotent stem cells

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

Targeting a GFP reporter gene to the MIXL1 locus of human embryonic stem cells identifies human primitive streak-like cells and enables isolation of primitive hematopoietic precursors.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

In vivo genome editing restores haemostasis in a mouse model of haemophilia

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV-GENET-112414-054926

Identifiers

DOI

10.1146/ANNUREV-GENET-112414-054926

1 reference

4 September 2017

1 reference