(Q38614302)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26493766%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

1 reference

20 July 2021

Complement, a target for therapy in inflammatory and degenerative diseases (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26493766%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

main subject

inflammation

0 references

complement activation

1 reference

20 July 2021

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26493766%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

author name string

Claire L Harris

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26493766%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

publication date

23 October 2015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26493766%20AND%20SRC:MED&resulttype=core&format=json

Nature Reviews Drug Discovery

28 February 2020

1 December 2015

1 reference

20 July 2021

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26493766%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

20 July 2021

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26493766%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

issue

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26493766%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

page(s)

857-877

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26493766%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/nrd4657

28 February 2020

exact match

0 references

cites work

Membrane complement regulatory proteins

1 reference

Are complement deficiencies really rare? Overview on prevalence, clinical importance and modern diagnostic approach

31 March 2020

1 reference

Complement dysregulation and disease: from genes and proteins to diagnostics and drugs.

31 March 2020

1 reference

Dense deposit disease and C3 glomerulopathy

31 March 2020

1 reference

Paroxysmal nocturnal hemoglobinuria and other complement-mediated hematological disorders

31 March 2020

1 reference

Paroxysmal nocturnal hemoglobinuria

31 March 2020

1 reference

Complement activation and inhibition in experimental models of arthritis

31 March 2020

1 reference

31 March 2020

1 reference

Therapeutic targeting of the complement system in age-related macular degeneration: a review.

31 March 2020

1 reference

Complement and immune complexes

31 March 2020

1 reference

Complement deficiencies and systemic lupus erythematosus

31 March 2020

1 reference

Role of complement in induction of antibody production in vivo. Effect of cobra factor and other C3-reactive agents on thymus-dependent and thymus-independent antibody responses

31 March 2020

1 reference

Regulation of humoral immunity by complement

31 March 2020

1 reference

Complement modulation of T cell immune responses during homeostasis and disease.

31 March 2020

1 reference

Complement: a key system for immune surveillance and homeostasis

31 March 2020

1 reference

Complement deficiencies in humans and animals: links to autoimmunity

31 March 2020

1 reference

Complement deficiency states and associated infections

31 March 2020

1 reference

Suppression of drusen formation by compstatin, a peptide inhibitor of complement C3 activation, on cynomolgus monkey with early-onset macular degeneration

31 March 2020

1 reference

A phase ia dose-escalation study of the anti-factor D monoclonal antibody fragment FCFD4514S in patients with geographic atrophy

31 March 2020

1 reference

Complement inhibitors targeted to the proximal tubule prevent injury in experimental nephrotic syndrome and demonstrate a key role for C5b-9

31 March 2020

1 reference

The complement receptor 2/factor H fusion protein TT30 protects paroxysmal nocturnal hemoglobinuria erythrocytes from complement-mediated hemolysis and C3 fragment.

31 March 2020

1 reference

Determination of the half-life of C3 in patients and its relation to the presence of C3-breakdown products and/or circulating immune complexes

31 March 2020

1 reference

Discovery and development of the complement inhibitor eculizumab for the treatment of paroxysmal nocturnal hemoglobinuria

31 March 2020

1 reference

Use of eculizumab for atypical haemolytic uraemic syndrome and C3 glomerulopathies

31 March 2020

1 reference

Pharmacokinetics and concentration-effect relationship of adalimumab in rheumatoid arthritis

31 March 2020

1 reference

Metabolism of the fifth component of complement, and its relation to metabolism of the third component, in patients with complement activation

31 March 2020

1 reference

Dynamics of complement activation in aHUS and how to monitor eculizumab therapy

31 March 2020

1 reference

Structural and Functional Analysis of a C3b-specific Antibody That Selectively Inhibits the Alternative Pathway of Complement

31 March 2020

1 reference

A humanized antibody that regulates the alternative pathway convertase: potential for therapy of renal disease associated with nephritic factors

31 March 2020

1 reference

31 March 2020

1 reference

Metabolism of complement factor D in renal failure

31 March 2020

1 reference

Complement inhibition in cynomolgus monkeys by anti-factor d antigen-binding fragment for the treatment of an advanced form of dry age-related macular degeneration

31 March 2020

1 reference

31 March 2020

Emerging PEGylated drugs

1 reference

Fc-based cytokines : prospects for engineering superior therapeutics

31 March 2020

1 reference

Phase I trial of the recombinant soluble complement receptor 1 in acute lung injury and acute respiratory distress syndrome

31 March 2020

1 reference

The role of complement in the early immune response to transplantation.

31 March 2020

1 reference

Serine protease inhibitor nafamostat given before reperfusion reduces inflammatory myocardial injury by complement and neutrophil inhibition

31 March 2020

1 reference

Inhibition of the serine proteases of the complement system

31 March 2020

1 reference

TNT003, an inhibitor of the serine protease C1s, prevents complement activation induced by cold agglutinins.

31 March 2020

1 reference

Structure-based inhibition of protein-protein interactions.

31 March 2020

1 reference

Structure-activity relationships for substrate-based inhibitors of human complement factor B.

31 March 2020

1 reference

Structures of C3b in complex with factors B and D give insight into complement convertase formation

31 March 2020

1 reference

Selective inhibition of the lectin pathway of complement with phage display selected peptides against mannose-binding lectin-associated serine protease (MASP)-1 and -2: significant contribution of MASP-1 to lectin pathway activation

31 March 2020

1 reference

Species dependence for binding of small molecule agonist and antagonists to the C5a receptor on polymorphonuclear leukocytes

31 March 2020

1 reference

Comparative functional evolution of human and mouse CR1 and CR2

31 March 2020

1 reference

The evolution of mouse and human complement C3-binding proteins: divergence of form but conservation of function

31 March 2020

1 reference

Microfluidic organs-on-chips.

31 March 2020

1 reference

Therapeutic inhibition of the early phase of complement activation

31 March 2020

1 reference

Toward a structure-based comprehension of the lectin pathway of complement

31 March 2020

1 reference

Noncompetitive allosteric inhibitors of the inflammatory chemokine receptors CXCR1 and CXCR2: prevention of reperfusion injury.

31 March 2020

1 reference

Neutrophil recruitment in the reperfused-injured rat liver was effectively attenuated by repertaxin, a novel allosteric noncompetitive inhibitor of CXCL8 receptors: a therapeutic approach for the treatment of post-ischemic hepatic syndromes

31 March 2020

1 reference

C1q-targeted monoclonal antibody prevents complement-dependent cytotoxicity and neuropathology in in vitro and mouse models of neuromyelitis optica

31 March 2020

1 reference

Specific inhibition of the classical complement pathway by C1q-binding peptides.

31 March 2020

1 reference

A novel peptide inhibitor of classical and lectin complement activation including ABO incompatibility.

31 March 2020

1 reference

Peptide inhibitor of complement c1, a novel suppressor of classical pathway activation: mechanistic studies and clinical potential.

31 March 2020

1 reference

Replacement therapy in hereditary angioedema: successful treatment of acute episodes of angioedema with partly purified C1 inhibitor

31 March 2020

1 reference

Therapeutic management of hereditary angioedema due to C1 inhibitor deficiency.

31 March 2020

1 reference

Genetically determined heterogeneity of the C1 esterase inhibitor in patients with hereditary angioneurotic edema

31 March 2020

1 reference

C1 esterase inhibitor concentrate in 1085 Hereditary Angioedema attacks--final results of the I.M.P.A.C.T.2 study

31 March 2020

1 reference

Long-term prophylaxis with C1-inhibitor (C1 INH) concentrate in patients with recurrent angioedema caused by hereditary and acquired C1-inhibitor deficiency

31 March 2020

1 reference

Escalating doses of C1 esterase inhibitor (CINRYZE) for prophylaxis in patients with hereditary angioedema

31 March 2020

1 reference

An evidence based therapeutic approach to hereditary and acquired angioedema

31 March 2020

1 reference

C1-inhibitor in patients with severe sepsis and septic shock: beneficial effect on renal dysfunction

31 March 2020

1 reference

C1-esterase inhibitor infusion increases survival rates for patients with sepsis*.

31 March 2020

1 reference

The effect of C1 inhibitor on myocardial ischemia and reperfusion injury

31 March 2020

1 reference

The effect of C1 inhibitor on intestinal ischemia and reperfusion injury

31 March 2020

1 reference

Design and synthesis of polyethylene glycol-modified biphenylsulfonyl-thiophene-carboxamidine inhibitors of the complement component C1s

31 March 2020

1 reference

Translational success stories: development of direct thrombin inhibitors

31 March 2020

1 reference

Monospecific Inhibitors Show That Both Mannan-binding Lectin-associated Serine Protease-1 (MASP-1) and -2 Are Essential for Lectin Pathway Activation and Reveal Structural Plasticity of MASP-2

31 March 2020

1 reference

Antibody-mediates inhibition of human C1s and the classical complement pathway

31 March 2020

1 reference

Hemolytic uremic syndrome: a factor H mutation (E1172Stop) causes defective complement control at the surface of endothelial cells

31 March 2020

1 reference

Treatment with human complement factor H rapidly reverses renal complement deposition in factor H-deficient mice

31 March 2020

1 reference

Intravitreal human complement factor H in a rat model of laser-induced choroidal neovascularisation

31 March 2020

1 reference

31 March 2020

1 reference

Rational engineering of a minimized immune inhibitor with unique triple-targeting properties

31 March 2020

1 reference

An engineered construct combining complement regulatory and surface-recognition domains represents a minimal-size functional factor H.

31 March 2020

1 reference

C4b-binding protein (C4BP) inhibits development of experimental arthritis in mice.

31 March 2020

1 reference

Recurrent infections in partial complement factor I deficiency: evaluation of three generations of a Brazilian family

31 March 2020

1 reference

Complotype affects the extent of down-regulation by Factor I of the C3b feedback cycle in vitro

31 March 2020

1 reference

Properdin in complement activation and tissue injury

31 March 2020

1 reference

Low-dose recombinant properdin provides substantial protection against Streptococcus pneumoniae and Neisseria meningitidis infection.

31 March 2020

1 reference

Soluble human complement receptor type 1: in vivo inhibitor of complement suppressing post-ischemic myocardial inflammation and necrosis

31 March 2020

1 reference

TP20 is superior to TP10 in reducing ischemia/reperfusion injury in rat lung grafts

31 March 2020

1 reference

Therapeutic efficacy of a novel membrane-targeted complement regulator in antigen-induced arthritis in the rat

31 March 2020

1 reference

Attenuation of myocardial reperfusion injury in pigs by Mirococept, a membrane-targeted complement inhibitor derived from human CR1

31 March 2020

1 reference

Deficient alternative complement pathway activation due to factor D deficiency by 2 novel mutations in the complement factor D gene in a family with meningococcal infections

31 March 2020

1 reference

Inhibiting Alternative Pathway Complement Activation by Targeting the Factor D Exosite

31 March 2020

1 reference

Structure of 3,4-dichloroisocoumarin-inhibited factor D

31 March 2020

1 reference

A lead discovery strategy driven by a comprehensive analysis of proteases in the peptide substrate space

31 March 2020

1 reference

Inhibitors of factor d may provide a treatment for age-related macular degeneration

31 March 2020

1 reference

Therapeutic inhibition of the alternative complement pathway attenuates chronic EAE.

31 March 2020

1 reference

Inhibition of the alternative complement pathway by antisense oligonucleotides targeting complement factor B improves lupus nephritis in mice

31 March 2020

1 reference

Inhibition of complement activation by recombinant Sh-CRIT-ed1 analogues

31 March 2020

1 reference

Intravascular activation of complement and acute lung injury. Dependency on neutrophils and toxic oxygen metabolites

31 March 2020

1 reference

Humanized cobra venom factor: structure, activity, and therapeutic efficacy in preclinical disease models

31 March 2020

1 reference

Inhibition of the Membrane Attack Complex of the Complement System Reduces Secondary Neuroaxonal Loss and Promotes Neurologic Recovery after Traumatic Brain Injury in Mice

31 March 2020

1 reference

The role of the anaphylatoxins in health and disease

31 March 2020

1 reference

Distinct roles of the anaphylatoxins C3a and C5a in dendritic cell-mediated allergic asthma

31 March 2020

1 reference

"Chemokine receptors as therapeutic targets: Why aren't there more drugs?".

31 March 2020

1 reference

Therapeutic activity of C5a receptor antagonists in a rat model of neurodegeneration

31 March 2020

1 reference

Blocking the receptor for C5a in patients with rheumatoid arthritis does not reduce synovial inflammation

31 March 2020

1 reference

The receptor for complement component C3a mediates protection from intestinal ischemia-reperfusion injuries by inhibiting neutrophil mobilization.

31 March 2020

1 reference

A novel C5a-neutralizing mirror-image (l-)aptamer prevents organ failure and improves survival in experimental sepsis

31 March 2020

1 reference

Targeting complement component 5a promotes vascular integrity and limits airway remodeling

31 March 2020

1 reference

Advances in the management of macular degeneration

31 March 2020

1 reference

Complement inhibitor of C5 activation from the soft tick Ornithodoros moubata.

31 March 2020

1 reference

Structure of and influence of a tick complement inhibitor on human complement component 5

31 March 2020

1 reference

In vivo characterization and therapeutic efficacy of a C5-specific inhibitor from the soft tick Ornithodoros moubata

31 March 2020

1 reference

Generation of a recombinant, membrane-targeted form of the complement regulator CD59: activity in vitro and in vivo.

31 March 2020

1 reference

Protection of erythrocytes from human complement-mediated lysis by membrane-targeted recombinant soluble CD59: a new approach to PNH therapy

31 March 2020

1 reference

Aurin tricarboxylic acid protects against red blood cell hemolysis in patients with paroxysmal nocturnal hemoglobinemia

31 March 2020

1 reference

Generation of anti-complement "prodrugs": cleavable reagents for specific delivery of complement regulators to disease sites.

31 March 2020

1 reference

Antibody-directed enzyme prodrug therapy (ADEPT) for cancer

31 March 2020

1 reference

Targeted complement inhibition by C3d recognition ameliorates tissue injury without apparent increase in susceptibility to infection

31 March 2020

1 reference

Targeted complement inhibitors protect against posttransplant cardiac ischemia and reperfusion injury and reveal an important role for the alternative pathway of complement activation

31 March 2020

1 reference

Design and development of TT30, a novel C3d-targeted C3/C5 convertase inhibitor for treatment of human complement alternative pathway-mediated diseases

31 March 2020

1 reference

Detection of complement activation using monoclonal antibodies against C3d.

31 March 2020

1 reference

Noninvasive detection of complement activation through radiologic imaging

31 March 2020

1 reference

The complotype: dictating risk for inflammation and infection

31 March 2020

1 reference

Common polymorphisms in C3, factor B, and factor H collaborate to determine systemic complement activity and disease risk

31 March 2020

1 reference

A common haplotype in the complement regulatory gene factor H (HF1/CFH) predisposes individuals to age-related macular degeneration

31 March 2020

1 reference

Complement factor H genetic variant and age-related macular degeneration: effect size, modifiers and relationship to disease subtype

31 March 2020

1 reference

Variation in factor B (BF) and complement component 2 (C2) genes is associated with age-related macular degeneration

31 March 2020

1 reference

Complement C3 variant and the risk of age-related macular degeneration

31 March 2020

1 reference

Age-related macular degeneration

31 March 2020

1 reference

Atypical hemolytic uremic syndrome

31 March 2020

1 reference

Mutations in factor H reduce binding affinity to C3b and heparin and surface attachment to endothelial cells in hemolytic uremic syndrome

31 March 2020

1 reference

Association of factor H autoantibodies with deletions of CFHR1, CFHR3, CFHR4, and with mutations in CFH, CFI, CD46, and C3 in patients with atypical hemolytic uremic syndrome

31 March 2020

1 reference

Generation of a monoclonal antibody to mouse C5 application in an ELISA assay for detection of anti-CS antibodies

31 March 2020

1 reference

Anti-C5 monoclonal antibody therapy prevents collagen-induced arthritis and ameliorates established disease

31 March 2020

1 reference

Inhibition of complement activity by humanized anti-C5 antibody and single-chain Fv.

31 March 2020

1 reference

Eculizumab: 5G1.1, h5G1.1, long-acting anti-C5 monoclonal antibody 5G1-1, long-acting anti-C5 monoclonal antibody 5G1.1.

31 March 2020

1 reference

Effect of eculizumab on hemolysis and transfusion requirements in patients with paroxysmal nocturnal hemoglobinuria

31 March 2020

1 reference

Multicenter phase 3 study of the complement inhibitor eculizumab for the treatment of patients with paroxysmal nocturnal hemoglobinuria

31 March 2020

1 reference

Long-term safety and efficacy of sustained eculizumab treatment in patients with paroxysmal nocturnal haemoglobinuria

31 March 2020

1 reference

Terminal complement inhibitor eculizumab in atypical hemolytic-uremic syndrome

31 March 2020

1 reference

A molecular insight into complement evasion by the staphylococcal complement inhibitor protein family

31 March 2020

1 reference

31 March 2020

1 reference

Genetic variants in C5 and poor response to eculizumab.

31 March 2020

1 reference

Protein-protein interaction inhibitors get into the groove

31 March 2020

1 reference

Structure of complement fragment C3b-factor H and implications for host protection by complement regulators

31 March 2020

1 reference

New analogs of the clinical complement inhibitor compstatin with subnanomolar affinity and enhanced pharmacokinetic properties

31 March 2020

1 reference

Compstatin: a C3-targeted complement inhibitor reaching its prime for bedside intervention

31 March 2020

1 reference

Update on current and future novel therapies for dry age-related macular degeneration

31 March 2020

1 reference

The amplification loop of the complement pathways.

31 March 2020

1 reference

Pharmacokinetics of plasma-derived C1-esterase inhibitor after subcutaneous versus intravenous administration in subjects with mild or moderate hereditary angioedema: the PASSION study

31 March 2020

1 reference

A phase I study of recombinant human C1 inhibitor in asymptomatic patients with hereditary angioedema

31 March 2020

1 reference

Recombinant human C1-esterase inhibitor relieves symptoms of hereditary angioedema attacks: phase 3, randomized, placebo-controlled trial

31 March 2020

1 reference

Spectrum of complement-mediated thrombotic microangiopathies: pathogenetic insights identifying novel treatment approaches

31 March 2020

1 reference

Eculizumab in AQP4-IgG-positive relapsing neuromyelitis optica spectrum disorders: an open-label pilot study.

31 March 2020

1 reference

Complement in multiple sclerosis: its role in disease and potential as a biomarker.

31 March 2020

1 reference

Systemic complement profiling in multiple sclerosis as a biomarker of disease state.

31 March 2020

1 reference

The role of complement and complement regulators in mediating motor nerve terminal injury in murine models of Guillain-Barré syndrome.

31 March 2020

1 reference

Emerging drugs for Guillain-Barré syndrome

31 March 2020

1 reference

The membrane attack pathway of complement drives pathology in passively induced experimental autoimmune myasthenia gravis in mice

31 March 2020

1 reference

A randomized, double-blind, placebo-controlled phase II study of eculizumab in patients with refractory generalized myasthenia gravis.

31 March 2020

1 reference

Dramatic effects of eculizumab in a child with diffuse proliferative lupus nephritis resistant to conventional therapy.

31 March 2020

1 reference

The genetics and immunobiology of IgA nephropathy

31 March 2020

1 reference

Eculizumab treatment for rescue of renal function in IgA nephropathy

31 March 2020

1 reference

Rheumatoid arthritis and the complement system.

31 March 2020

1 reference

Association of genetic variants of mannan-binding (MBL) lectin-2 gene, MBL levels and function in ulcerative colitis and Crohn's disease

31 March 2020

1 reference

Regulation of the alternative pathway of complement modulates injury and immunity in a chronic model of dextran sulphate sodium-induced colitis.

31 March 2020

1 reference

Long-term response of refractory primary cold agglutinin disease to eculizumab therapy.

31 March 2020

1 reference

Complement and cutaneous autoimmune blistering diseases.

31 March 2020

1 reference

Complement and the antiphospholipid syndrome

31 March 2020

1 reference

Eculizumab Prevents Recurrent Antiphospholipid Antibody Syndrome and Enables Successful Renal Transplantation

31 March 2020

1 reference

Association of C2 and CFB polymorphisms with anterior uveitis.

31 March 2020

1 reference

Pathogenesis of ANCA-associated vasculitis: new possibilities for intervention.

31 March 2020

1 reference

The membrane attack complex of complement drives the progression of atherosclerosis in apolipoprotein E knockout mice

31 March 2020

1 reference

The complement system in human cardiometabolic disease

31 March 2020

1 reference

Label-free quantitative proteomic analysis reveals dysfunction of complement pathway in peripheral blood of schizophrenia patients: evidence for the immune hypothesis of schizophrenia.

31 March 2020

1 reference

The complement control-related genes CSMD1 and CSMD2 associate to schizophrenia.

31 March 2020

1 reference

A complex role for complement in allergic asthma

31 March 2020

1 reference

Complement components as potential therapeutic targets for asthma treatment

31 March 2020

1 reference

Complement factors c3a, c4a, and c5a in chronic obstructive pulmonary disease and asthma

31 March 2020

1 reference

Role of complement in a murine model of peanut-induced anaphylaxis

31 March 2020

1 reference

Peanuts can contribute to anaphylactic shock by activating complement.

31 March 2020

1 reference

Role of complement in multiorgan failure

31 March 2020

1 reference

Double blockade of CD14 and complement C5 abolishes the cytokine storm and improves morbidity and survival in polymicrobial sepsis in mice

31 March 2020

1 reference

Experimental cerebral malaria: the murine model provides crucial insight into the role of complement

31 March 2020

1 reference

Immunomodulation in psoriatic arthritis: focus on cellular and molecular pathways

31 March 2020

1 reference

Potential therapeutic targets for idiopathic inflammatory myopathies.

31 March 2020

1 reference

Identification of a central role for complement in osteoarthritis

31 March 2020

1 reference

Brief report: carboxypeptidase B serves as a protective mediator in osteoarthritis

31 March 2020

1 reference

Innate immunity and the etiology of late-onset Alzheimer's disease.

31 March 2020

1 reference

Inflammation in Alzheimer disease-a brief review of the basic science and clinical literature

31 March 2020

1 reference

The role of the classical complement cascade in synapse loss during development and glaucoma

31 March 2020

1 reference

Diabetic angiopathy, the complement system and the tumor necrosis factor superfamily

31 March 2020

1 reference

Complement involvement in neovascular ocular diseases.

31 March 2020

1 reference

Soluble form of membrane attack complex independently predicts mortality and cardiovascular events in patients with ST-elevation myocardial infarction treated with primary percutaneous coronary intervention

31 March 2020

1 reference

Targeting mannose-binding lectin confers long-lasting protection with a surprisingly wide therapeutic window in cerebral ischemia.

31 March 2020

1 reference

C1-inhibitor protects from brain ischemia-reperfusion injury by combined antiinflammatory and antithrombotic mechanisms.

31 March 2020

1 reference

The role of complement in trauma and fracture healing

31 March 2020

1 reference

The complement system in ischemia-reperfusion injuries

31 March 2020

1 reference

Targeted complement inhibition as a promising strategy for preventing inflammatory complications in hemodialysis

31 March 2020

1 reference

Therapeutic C3 inhibitor Cp40 abrogates complement activation induced by modern hemodialysis filters

31 March 2020

1 reference

STEC-HUS, atypical HUS and TTP are all diseases of complement activation

31 March 2020

1 reference

Systemic complement inhibition with eculizumab for geographic atrophy in age-related macular degeneration: the COMPLETE study

31 March 2020

1 reference

Terminal complement inhibition decreases antibody-mediated rejection in sensitized renal transplant recipients

31 March 2020

1 reference

Immunosuppressant and immunomodulatory treatment for dermatomyositis and polymyositis

31 March 2020

1 reference

12 December 2020

Soluble human complement receptor 1 limits ischemic damage in cardiac surgery patients at high risk requiring cardiopulmonary bypass.

1 reference

12 December 2020

The modulation of the alternative pathway of complement in C2-deficient human serum by changes in concentration of the component and control proteins

1 reference

12 December 2020

Compstatin: a complement inhibitor on its way to clinical application

1 reference

12 December 2020

Three cases of factor I deficiency: the effect of treatment with plasma

1 reference

12 December 2020

C4 binding protein deficiency in a patient with atypical Behçet's disease

1 reference

12 December 2020

High-density lipoproteins can act as carriers of glycophosphoinositol lipid-anchored CD59 in human plasma

1 reference

12 December 2020

Inhibition of human complement by a C3-binding peptide isolated from a phage-displayed random peptide library.

1 reference

12 December 2020

The effects of a cobra venom factor and ethyl palmitate on the prolongation of survival of heterologous erythrocytes

1 reference

12 December 2020

[Decomplementization by a factor extracted from cobra venom. Effect on several immune reactions of the guinea pig and rat]

1 reference

12 December 2020

Eculizumab (Alexion).

1 reference

12 December 2020

Complement system in psoriatic arthritis: a useful marker in response prediction and monitoring of anti-TNF treatment.

1 reference

12 December 2020

Gene therapy in age related macular degeneration and hereditary macular disorders

1 reference

12 December 2020