(Q38729876)

5 September 2017

Genome-wide CRISPR screens reveal a Wnt-FZD5 signaling circuit as a druggable vulnerability of RNF43-mutant pancreatic tumors (English)

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Corrigendum: Genome-wide CRISPR screens reveal a Wnt-FZD5 signaling circuit as a druggable vulnerability of RNF43-mutant pancreatic tumors.

5 September 2017

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corrigendum / erratum

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Mélanie Robitaille

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Traver Hart

object named as

Traver Hart

4

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Stephane Angers

object named as

Stéphane Angers

17

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Hans Clevers

14

object named as

Hans Clevers

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5 September 2017

Zachary Steinhart

1

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5 September 2017

Zvezdan Pavlovic

2

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5 September 2017

Megha Chandrashekhar

3

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5 September 2017

Xiaowei Wang

5

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5 September 2017

Xiaoyu Zhang

6

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5 September 2017

Kevin R Brown

8

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5 September 2017

Sridevi Jaksani

9

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5 September 2017

René Overmeer

10

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5 September 2017

Sylvia F Boj

11

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5 September 2017

Jarrett Adams

12

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5 September 2017

James Pan

13

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5 September 2017

Sachdev Sidhu

15

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5 September 2017

Jason Moffat

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5 September 2017

language of work or name

English

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publication date

21 November 2016

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5 September 2017

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5 September 2017

23

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1

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5 September 2017

60-68

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https://scigraph.springernature.com/pub.10.1038/nm.4219

5 September 2017

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cites work

Mechanisms of Wnt signaling in development

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7 January 2021

Adult mammalian stem cells: the role of Wnt, Lgr5 and R-spondins

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7 January 2021

WNT signalling pathways as therapeutic targets in cancer

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7 January 2021

Wnt signaling in cancer

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7 January 2021

Targeting Wnts at the source--new mechanisms, new biomarkers, new drugs

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7 January 2021

Whole genomes redefine the mutational landscape of pancreatic cancer

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7 January 2021

Mutational landscape of mucinous ovarian carcinoma and its neoplastic precursors

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7 January 2021

Whole-genome sequencing and comprehensive molecular profiling identify new driver mutations in gastric cancer.

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7 January 2021

RNF43 is frequently mutated in colorectal and endometrial cancers

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7 January 2021

Identifying candidate colon cancer tumor suppressor genes using inhibition of nonsense-mediated mRNA decay in colon cancer cells

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7 January 2021

Tumour suppressor RNF43 is a stem-cell E3 ligase that induces endocytosis of Wnt receptors

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7 January 2021

ZNRF3 promotes Wnt receptor turnover in an R-spondin-sensitive manner

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7 January 2021

Porcupine inhibitor suppresses paracrine Wnt-driven growth of Rnf43;Znrf3-mutant neoplasia

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7 January 2021

Inactivating mutations of RNF43 confer Wnt dependency in pancreatic ductal adenocarcinoma

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7 January 2021

Development and applications of CRISPR-Cas9 for genome engineering

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7 January 2021

High-Resolution CRISPR Screens Reveal Fitness Genes and Genotype-Specific Cancer Liabilities.

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7 January 2021

Genome-scale CRISPR-Cas9 knockout screening in human cells

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7 January 2021

Identification and characterization of essential genes in the human genome.

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7 January 2021

Genetic screens in human cells using the CRISPR-Cas9 system

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7 January 2021

BAGEL: a computational framework for identifying essential genes from pooled library screens.

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7 January 2021

Measuring error rates in genomic perturbation screens: gold standards for human functional genomics

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7 January 2021

Genomic Copy Number Dictates a Gene-Independent Cell Response to CRISPR/Cas9 Targeting

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7 January 2021

Easy quantitative assessment of genome editing by sequence trace decomposition

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7 January 2021

CDR-H3 Diversity Is Not Required for Antigen Recognition by Synthetic Antibodies

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7 January 2021

Wnt pathway inhibition via the targeting of Frizzled receptors results in decreased growth and tumorigenicity of human tumors

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7 January 2021

Genome-wide association study of pancreatic cancer in Japanese population

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7 January 2021

Frequent frameshift mutations in 2 mononucleotide repeats of RNF43 gene and its regional heterogeneity in gastric and colorectal cancers

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7 January 2021

Prospective derivation of a living organoid biobank of colorectal cancer patients.

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7 January 2021

Wnt7b is required for epithelial progenitor growth and operates during epithelial-to-mesenchymal signaling in pancreatic development.

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7 January 2021

WNT7B mediates autocrine Wnt/β-catenin signaling and anchorage-independent growth in pancreatic adenocarcinoma

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7 January 2021

Systematic mapping of WNT-FZD protein interactions reveals functional selectivity by distinct WNT-FZD pairs.

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7 January 2021

High-throughput real-time quantitative reverse transcription PCR

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7 January 2021

A comprehensive transcriptional portrait of human cancer cell lines

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7 January 2021

A roadmap to generate renewable protein binders to the human proteome

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7 January 2021

High-throughput generation of synthetic antibodies from highly functional minimalist phage-displayed libraries

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7 January 2021

Simplified synthetic antibody libraries

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7 January 2021

Identifiers

DOI

10.1038/NM.4219

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Dimensions Publication ID

5 September 2017

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