(Q38747530)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26908138%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

title

Physiological and Pathophysiological Implications of Synaptic Tau (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26908138%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26908138%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

Daniel J. Whitcomb

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26908138%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

Kwangwook Cho

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26908138%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

author name string

Philip Regan

1

1 reference

6 September 2017

Daniel J Whitcomb

2

1 reference

6 September 2017

Kwangwook Cho

3

1 reference

6 September 2017

language of work or name

1 reference

7 July 2016

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26908138%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26908138%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

volume

23

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26908138%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26908138%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

page(s)

137-151

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26908138%20AND%20SRC:MED&resulttype=core&format=json

An N-methyl-D-aspartate-receptor dependent, late-phase long-term depression in middle-aged mice identifies no GluN2-subunit bias.

8 March 2020

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Early investigational drugs targeting tau protein for the treatment of Alzheimer's disease

21 January 2018

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Structure and novel exons of the human tau gene

21 January 2018

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Diabetes-, stress- and ageing-related changes in synaptic plasticity in hippocampus and neocortex--the same metaplastic process?

21 January 2018

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Phosphorylation of Ser262 strongly reduces binding of tau to microtubules: distinction between PHF-like immunoreactivity and microtubule binding.

21 January 2018

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The distribution of tau in the mammalian central nervous system

21 January 2018

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Inhibition of neurite polarity by tau antisense oligonucleotides in primary cerebellar neurons

21 January 2018

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Tau protein is involved in morphological plasticity in hippocampal neurons in response to BDNF.

21 January 2018

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Amyloid beta-protein fragments 25-35 and 31-35 potentiate long-term depression in hippocampal CA1 region of rats in vivo.

21 January 2018

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Glycogen synthase kinase 3 beta induces caspase-cleaved tau aggregation in situ

21 January 2018

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Calcium binding to PICK1 is essential for the intracellular retention of AMPA receptors underlying long-term depression

21 January 2018

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Transmission and spreading of tauopathy in transgenic mouse brain

21 January 2018

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Long-term depression in the CNS.

21 January 2018

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Propagation of tau pathology in a model of early Alzheimer's disease

21 January 2018

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Pro-aggregant Tau impairs mossy fiber plasticity due to structural changes and Ca(++) dysregulation

21 January 2018

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Site-specific phosphorylation and caspase cleavage differentially impact tau-microtubule interactions and tau aggregation

21 January 2018

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Differential regulation of dynein and kinesin motor proteins by tau

21 January 2018

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Hippocampal long-term depression mediates spatial reversal learning in the Morris water maze.

21 January 2018

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Modulation of the dynamic instability of tubulin assembly by the microtubule-associated protein tau

21 January 2018

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Homosynaptic long-term depression in area CA1 of hippocampus and effects of N-methyl-D-aspartate receptor blockade

21 January 2018

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Selective phosphorylation of adult tau isoforms in mature hippocampal neurons exposed to fibrillar A beta.

21 January 2018

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Activity-dependent tau protein translocation to excitatory synapse is disrupted by exposure to amyloid-beta oligomers.

21 January 2018

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Astrocytes are important mediators of Aβ-induced neurotoxicity and tau phosphorylation in primary culture.

21 January 2018

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Frontotemporal dementia: implications for understanding Alzheimer disease

21 January 2018

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Phosphorylation of microtubule-associated protein tau by stress-activated protein kinases

21 January 2018

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Tau proteins of Alzheimer paired helical filaments: abnormal phosphorylation of all six brain isoforms

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416633439

Cloning and sequencing of the cDNA encoding a core protein of the paired helical filament of Alzheimer disease: identification as the microtubule-associated protein tau

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416633439

Characteristics and consequences of muscarinic receptor activation by tau protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416633439

Abnormal phosphorylation of the microtubule-associated protein tau (tau) in Alzheimer cytoskeletal pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416633439

Tau Oligomers: The Toxic Player at Synapses in Alzheimer's Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416633439

PICK1 is a calcium-sensor for NMDA-induced AMPA receptor trafficking

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416633439

The brain-derived neurotrophic factor Val66Met polymorphism is associated with age-related change in reasoning skills.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416633439

Tau proteins: the molecular structure and mode of binding on microtubules

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416633439

Tau mislocalization to dendritic spines mediates synaptic dysfunction independently of neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416633439

AMPAR removal underlies Abeta-induced synaptic depression and dendritic spine loss

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416633439

Association of missense and 5'-splice-site mutations in tau with the inherited dementia FTDP-17

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416633439

Dendritic function of tau mediates amyloid-beta toxicity in Alzheimer's disease mouse models

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416633439

Truncated tau deregulates synaptic markers in rat model for human tauopathy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416633439

Increased risk of type 2 diabetes in Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416633439

Dynamic microtubules regulate dendritic spine morphology and synaptic plasticity

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416633439

Aβ(1-42) inhibition of LTP is mediated by a signaling pathway involving caspase-3, Akt1 and GSK-3β.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416633439

Activation of a synapse weakening pathway by human Val66 but not Met66 pro-brain-derived neurotrophic factor (proBDNF)

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416633439

Hippocampal long-term depression: master or minion in declarative memory processes?

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416633439

Different forms of LTD in the CA1 region of the hippocampus: role of age and stimulus protocol.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416633439

Behavioral stress modifies hippocampal plasticity through N-methyl-D-aspartate receptor activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416633439

Caspase-cleaved tau exhibits rapid memory impairment associated with tau oligomers in a transgenic mouse model

21 January 2018

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Microtubule-associated protein tau is essential for long-term depression in the hippocampus

21 January 2018

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https://api.crossref.org/works/10.1177%2F1073858416633439

Presynaptic long-term depression at the hippocampal mossy fiber-CA3 synapse.

21 January 2018

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https://api.crossref.org/works/10.1177%2F1073858416633439

Microtubule-associated protein tau (tau) is a major antigenic component of paired helical filaments in Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416633439

Axonal disruption and aberrant localization of tau protein characterize the neuropil pathology of Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416633439

Tau neurotoxicity and rescue in animal models of human Tauopathies

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416633439

Heterogeneity of Tau proteins during mouse brain development and differentiation of cultured neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416633439

Soluble oligomers of amyloid Beta protein facilitate hippocampal long-term depression by disrupting neuronal glutamate uptake

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416633439

Novel diffusion barrier for axonal retention of Tau in neurons and its failure in neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416633439

Caspase-3 activation via mitochondria is required for long-term depression and AMPA receptor internalization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416633439

Profiling murine tau with 0N, 1N and 2N isoform-specific antibodies in brain and peripheral organs reveals distinct subcellular localization, with the 1N isoform being enriched in the nucleus

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416633439

Trans-synaptic spread of tau pathology in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416633439

PACSIN1, a Tau-interacting protein, regulates axonal elongation and branching by facilitating microtubule instability

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416633439

Tau immunization: a cautionary tale?

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416633439

Experimental diabetes in rats causes hippocampal dendritic and synaptic reorganization and increased glucocorticoid reactivity to stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416633439

The CAMKK2-AMPK kinase pathway mediates the synaptotoxic effects of Aβ oligomers through Tau phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416633439

Tau mRNA is present in axonal RNA granules and is associated with elongation factor 1A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416633439

Glycogen synthase kinase-3 and the Alzheimer-like state of microtubule-associated protein tau.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416633439

Biopsy-derived adult human brain tau is phosphorylated at many of the same sites as Alzheimer's disease paired helical filament tau.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416633439

Tau phosphorylation and tau mislocalization mediate soluble Aβ oligomer-induced AMPA glutamate receptor signaling deficits.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416633439

The potential for beta-structure in the repeat domain of tau protein determines aggregation, synaptic decay, neuronal loss, and coassembly with endogenous Tau in inducible mouse models of tauopathy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416633439

Cleavage and conformational changes of tau protein follow phosphorylation during Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416633439

Phosphorylation of tau protein at sites Ser(396-404) is one of the earliest events in Alzheimer's disease and Down syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416633439

Interaction of endogenous tau protein with synaptic proteins is regulated by N-methyl-D-aspartate receptor-dependent tau phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416633439

Proline-directed and non-proline-directed phosphorylation of PHF-tau.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416633439

Tau post-translational modifications in wild-type and human amyloid precursor protein transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416633439

21 January 2018

The many faces of tau

1 reference

https://api.crossref.org/works/10.1177%2F1073858416633439

Mechanisms underlying induction of homosynaptic long-term depression in area CA1 of the hippocampus

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416633439

Phosphorylation of tau and alpha-synuclein in synaptic-enriched fractions of the frontal cortex in Alzheimer's disease, and in Parkinson's disease and related alpha-synucleinopathies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416633439

Clinicopathologic and 11C-Pittsburgh compound B implications of Thal amyloid phase across the Alzheimer's disease spectrum

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416633439

Engineering a memory with LTD and LTP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416633439

Rare individual amyloid-β oligomers act on astrocytes to initiate neuronal damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416633439

Correlation of Alzheimer disease neuropathologic changes with cognitive status: a review of the literature

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416633439

Transgenic mice lacking NMDAR-dependent LTD exhibit deficits in behavioral flexibility

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416633439

Inhibition of glycogen synthase kinase-3 by lithium correlates with reduced tauopathy and degeneration in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416633439

NMDA receptor subunit diversity: impact on receptor properties, synaptic plasticity and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416633439

Phosphorylation determines two distinct species of Tau in the central nervous system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416633439

Tau immunotherapy for Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416633439

A systematic investigation of the protein kinases involved in NMDA receptor-dependent LTD: evidence for a role of GSK-3 but not other serine/threonine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416633439

LTP inhibits LTD in the hippocampus via regulation of GSK3beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416633439

Dissecting phenotypic traits linked to human resilience to Alzheimer's pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416633439

Alterations in glucose metabolism induce hypothermia leading to tau hyperphosphorylation through differential inhibition of kinase and phosphatase activities: implications for Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416633439

Obesity, diabetes, and leptin resistance promote tau pathology in a mouse model of disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416633439

Physiological release of endogenous tau is stimulated by neuronal activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416633439

Tau is essential to beta -amyloid-induced neurotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416633439

Tau phosphorylation at serine 396 residue is required for hippocampal LTD

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416633439

Phosphorylation regulates tau interactions with Src homology 3 domains of phosphatidylinositol 3-kinase, phospholipase Cgamma1, Grb2, and Src family kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416633439

Reducing endogenous tau ameliorates amyloid beta-induced deficits in an Alzheimer's disease mouse model

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416633439

Hippocampal synaptic loss in early Alzheimer's disease and mild cognitive impairment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416633439

Alzheimer's disease is a synaptic failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416633439

A novel GSK-3beta inhibitor reduces Alzheimer's pathology and rescues neuronal loss in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416633439

Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416633439

Tau protein is required for amyloid {beta}-induced impairment of hippocampal long-term potentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416633439

Pre-synaptic C-terminal truncated tau is released from cortical synapses in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416633439

Analysis of tau post-translational modifications in rTg4510 mice, a model of tau pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416633439

Stress acts cumulatively to precipitate Alzheimer's disease-like tau pathology and cognitive deficits.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416633439

Chronic psychosocial stress exacerbates impairment of cognition and long-term potentiation in beta-amyloid rat model of Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416633439

Diabetes impairs hippocampal function through glucocorticoid-mediated effects on new and mature neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416633439

Reversibility of Tau-related cognitive defects in a regulatable FTD mouse model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416633439

The synaptic accumulation of hyperphosphorylated tau oligomers in Alzheimer disease is associated with dysfunction of the ubiquitin-proteasome system

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416633439

Somatodendritic localization of phosphorylated tau in neonatal and adult rat cerebral cortex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416633439

Tyrosine phosphorylation of tau regulates its interactions with Fyn SH2 domains, but not SH3 domains, altering the cellular localization of tau.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416633439

Cognitive defects are reversible in inducible mice expressing pro-aggregant full-length human Tau.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416633439

Association between the BDNF 196 A/G polymorphism and sporadic Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416633439

The role of type 2 diabetes in neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416633439

The brain-derived neurotrophic factor Val66Met polymorphism and prediction of neural risk for Alzheimer disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416633439

mTOR-mediated hyperphosphorylation of tau in the hippocampus is involved in cognitive deficits in streptozotocin-induced diabetic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416633439

A protein factor essential for microtubule assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416633439

Muscarinic acetylcholine receptors: mutant mice provide new insights for drug development

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416633439

Tauopathies: classification and clinical update on neurodegenerative diseases associated with microtubule-associated protein tau

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416633439

Pseudophosphorylation of Tau at distinct epitopes or the presence of the P301L mutation targets the microtubule-associated protein Tau to dendritic spines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416633439

Behavioural stress facilitates the induction of long-term depression in the hippocampus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416633439

Glycogen Synthase Kinase 3β-mediated Phosphorylation in the Most C-terminal Region of Protein Interacting with C Kinase 1 (PICK1) Regulates the Binding of PICK1 to Glutamate Receptor Subunit GluA2

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416633439

Neuronal activity regulates extracellular tau in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416633439

Starvation induces tau hyperphosphorylation in mouse brain: implications for Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416633439

Behavioral stress modifies hippocampal synaptic plasticity through corticosterone-induced sustained extracellular signal-regulated kinase/mitogen-activated protein kinase activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416633439

Developmental regulation of tau phosphorylation, tau kinases, and tau phosphatases

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416633439

Amyloid-β oligomers induce synaptic damage via Tau-dependent microtubule severing by TTLL6 and spastin

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416633439

Abeta oligomers cause localized Ca(2+) elevation, missorting of endogenous Tau into dendrites, Tau phosphorylation, and destruction of microtubules and spines

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416633439

Appoptosin-Mediated Caspase Cleavage of Tau Contributes to Progressive Supranuclear Palsy Pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1073858416633439

21 January 2018

Identifiers

DOI

10.1177/1073858416633439

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26908138%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

1 reference