(Q38779102)

PubMed publication ID

26988744

6 September 2017

title

A critical appraisal of the pathogenic protein spread hypothesis of neurodegeneration (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6701169&resulttype=core&format=json

11 May 2020

1 reference

2

Dennis J Selkoe

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6701169&resulttype=core&format=json

11 May 2020

author name string

Dominic M Walsh

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6701169&resulttype=core&format=json

11 May 2020

language of work or name

English

0 references

publication date

1 March 2016

1 reference

PubMed publication ID

26988744

Nature Reviews Neuroscience

6 September 2017

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6701169&resulttype=core&format=json

11 May 2020

volume

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6701169&resulttype=core&format=json

11 May 2020

issue

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6701169&resulttype=core&format=json

11 May 2020

page(s)

251-260

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6701169&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/nrn.2016.13

11 May 2020

exact match

0 references

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Lewy body-like pathology in long-term embryonic nigral transplants in Parkinson's disease

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Neuropathology in transplants in Parkinson's disease: implications for disease pathogenesis and the future of cell therapy

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Transgene expression in the Nop-tTA driver line is not inherently restricted to the entorhinal cortex

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31 March 2020

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Brain homogenates from human tauopathies induce tau inclusions in mouse brain

31 March 2020

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Templated misfolding of Tau by prion-like seeding along neuronal connections impairs neuronal network function and associated behavioral outcomes in Tau transgenic mice

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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α-Synuclein and tau concentrations in cerebrospinal fluid of patients presenting with parkinsonism: a cohort study

31 March 2020

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Passive immunization reduces behavioral and neuropathological deficits in an alpha-synuclein transgenic model of Lewy body disease

31 March 2020

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31 March 2020

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31 March 2020

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Prions and their partners in crime

31 March 2020

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Release of the cellular prion protein from cultured cells after loss of its glycoinositol phospholipid anchor

31 March 2020

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Processing of a cellular prion protein: identification of N- and C-terminal cleavage sites.

31 March 2020

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Prions: generation and spread versus neurotoxicity.

31 March 2020

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Prion neuropathology follows the accumulation of alternate prion protein isoforms after infective titre has peaked.

31 March 2020

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Prion diseases: what is the neurotoxic molecule?

31 March 2020

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A general model of prion strains and their pathogenicity

31 March 2020

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Direct evidence of Parkinson pathology spread from the gastrointestinal tract to the brain in rats

31 March 2020

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Parkinson's disease: an immunohistochemical study of Lewy body-containing neurons in the enteric nervous system

31 March 2020

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Is Parkinson's disease a primary olfactory disorder?

31 March 2020

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α-Synuclein in cutaneous autonomic nerves

31 March 2020

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31 March 2020

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Conformational diversity of wild-type Tau fibrils specified by templated conformation change

31 March 2020

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Inclusion formation and neuronal cell death through neuron-to-neuron transmission of alpha-synuclein

31 March 2020

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Transmission of multiple system atrophy prions to transgenic mice

31 March 2020

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Cell-to-cell transmission of pathogenic proteins in neurodegenerative diseases

31 March 2020

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Tau Trimers Are the Minimal Propagation Unit Spontaneously Internalized to Seed Intracellular Aggregation.

31 March 2020

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Internalized Tau Oligomers Cause Neurodegeneration by Inducing Accumulation of Pathogenic Tau in Human Neurons Derived from Induced Pluripotent Stem Cells.

31 March 2020

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Iatrogenic Creutzfeldt-Jakob disease at the millennium.

31 March 2020

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Clinical presentation and pre-mortem diagnosis of variant Creutzfeldt-Jakob disease associated with blood transfusion: a case report.

31 March 2020

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Variant Creutzfeldt-Jakob disease.

31 March 2020

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A new variant of Creutzfeldt-Jakob disease in the UK.

31 March 2020

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Is there a risk of prion-like disease transmission by Alzheimer- or Parkinson-associated protein particles?

31 March 2020

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Evaluation of potential infectivity of Alzheimer and Parkinson disease proteins in recipients of cadaver-derived human growth hormone

31 March 2020

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Evidence for and against the transmissibility of Alzheimer disease

31 March 2020

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Evidence against the transmissibility of Alzheimer's disease

31 March 2020

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Human spongiform encephalopathy: the National Institutes of Health series of 300 cases of experimentally transmitted disease

31 March 2020

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Induction of beta (A4)-amyloid in primates by injection of Alzheimer's disease brain homogenate. Comparison with transmission of spongiform encephalopathy

31 March 2020

1 reference

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Towards non-invasive diagnostic imaging of early-stage Alzheimer's disease.

31 March 2020

1 reference

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Oral treatment targeting the unfolded protein response prevents neurodegeneration and clinical disease in prion-infected mice

31 March 2020

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Encephalopathy in mice produced by inoculation with scrapie brain material.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2016.13

Experimental transmission of a Kuru-like syndrome to chimpanzees

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2016.13

Creutzfeldt-Jakob Disease (Spongiform Encephalopathy): Transmission to the Chimpanzee

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2016.13

Self-replication and scrapie

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2016.13

Identification of a protein that purifies with the scrapie prion.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2016.13

A cellular gene encodes scrapie PrP 27-30 protein

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2016.13

Identification of scrapie prion protein-specific mRNA in scrapie-infected and uninfected brain

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2016.13

Spontaneous neurodegeneration in transgenic mice with mutant prion protein

31 March 2020

1 reference

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Genetics of prion diseases

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2016.13

Mice devoid of PrP are resistant to scrapie

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2016.13

A kinetic model for amyloid formation in the prion diseases: importance of seeding

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2016.13

Prionics or the kinetic basis of prion diseases

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2016.13

Proliferation of amyloid-β42 aggregates occurs through a secondary nucleation mechanism

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2016.13

The most infectious prion protein particles.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2016.13

Eight prion strains have PrP(Sc) molecules with different conformations

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2016.13

Detection and characterization of proteinase K-sensitive disease-related prion protein with thermolysin.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2016.13

Prion propagation and toxicity in vivo occur in two distinct mechanistic phases

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2016.13

Evidence for seeding of beta -amyloid by intracerebral infusion of Alzheimer brain extracts in beta -amyloid precursor protein-transgenic mice.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2016.13

Exogenous induction of cerebral beta-amyloidogenesis is governed by agent and host

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2016.13

Exogenous seeding of cerebral β-amyloid deposition in βAPP-transgenic rats

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2016.13

Purified and synthetic Alzheimer's amyloid beta (Aβ) prions

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2016.13

Models of amyloid seeding in Alzheimer's disease and scrapie: mechanistic truths and physiological consequences of the time-dependent solubility of amyloid proteins

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2016.13

On the lag phase in amyloid fibril formation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2016.13

Amyloid-β oligomerization in Alzheimer dementia versus high-pathology controls

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2016.13

Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2016.13

Mutation of the E6-AP ubiquitin ligase reduces nuclear inclusion frequency while accelerating polyglutamine-induced pathology in SCA1 mice.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2016.13

Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2016.13

Beneficial effect of human anti-amyloid-beta active immunization on neurite morphology and tau pathology

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2016.13

Oligomeric amyloid beta associates with postsynaptic densities and correlates with excitatory synapse loss near senile plaques

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2016.13

Soluble Aβ seeds are potent inducers of cerebral β-amyloid deposition

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2016.13

Peripherally applied Abeta-containing inoculates induce cerebral beta-amyloidosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2016.13

Evidence for human transmission of amyloid-β pathology and cerebral amyloid angiopathy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2016.13

Erratum: Evidence for human transmission of amyloid-β pathology and cerebral amyloid angiopathy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2016.13

Proteomic analysis of dendritic cell-derived exosomes: a secreted subcellular compartment distinct from apoptotic vesicles

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2016.13

Nanotubular highways for intercellular organelle transport

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2016.13

Getting a grip on prions: oligomers, amyloids, and pathological membrane interactions

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2016.13

Alpha-synuclein in Lewy body disease and Alzheimer's disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2016.13

Dendritic function of tau mediates amyloid-beta toxicity in Alzheimer's disease mouse models

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2016.13

Amyloid-β oligomers induce synaptic damage via Tau-dependent microtubule severing by TTLL6 and spastin

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2016.13

C-Terminally Truncated Forms of Tau, But Not Full-Length Tau or Its C-Terminal Fragments, Are Released from Neurons Independently of Cell Death.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2016.13

Personalized medicine approach for optimizing the dose of tafamidis to potentially ameliorate wild-type transthyretin amyloidosis (cardiomyopathy).

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2016.13

Parkinson-causing α-synuclein missense mutations shift native tetramers to monomers as a mechanism for disease initiation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2016.13

α-Synuclein occurs physiologically as a helically folded tetramer that resists aggregation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRN.2016.13

31 March 2020

1 reference

12 December 2020

Do neuronal inclusions kill the cell?

1 reference

12 December 2020

Degenerative disease of the central nervous system in New Guinea; the endemic occurrence of kuru in the native population

1 reference

12 December 2020

"Friendly fire" in medicine: hormones, homografts, and Creutzfeldt-Jakob disease

1 reference

12 December 2020

1 reference

12 December 2020

Prion neurotoxicity: insights from prion protein mutants

1 reference

12 December 2020

Proteolytic processing of the prion protein in health and disease.

1 reference

12 December 2020

Relationship of neighboring tissue and gliosis to α-synuclein pathology in a fetal transplant for Parkinson's disease

1 reference

12 December 2020

Transport and targeting of scrapie infectivity and pathology in the optic nerve projections following intraocular infection

1 reference

12 December 2020

Evidence for the experimental transmission of cerebral beta-amyloidosis to primates

1 reference

12 December 2020

Identifiers

DOI

10.1038/NRN.2016.13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6701169&resulttype=core&format=json

Dimensions Publication ID

11 May 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6701169&resulttype=core&format=json

11 May 2020

PubMed publication ID

26988744

1 reference