(Q38812588)

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Expert consensus document: Cholangiocarcinoma: current knowledge and future perspectives consensus statement from the European Network for the Study of Cholangiocarcinoma (ENS-CCA).

scientific article published on 20 April 2016

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2 April 2020

Expert consensus document: Cholangiocarcinoma: current knowledge and future perspectives consensus statement from the European Network for the Study of Cholangiocarcinoma (ENS-CCA) (English)

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2 April 2020

cholangiocarcinoma

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Gastrin inhibits cholangiocarcinoma growth through increased apoptosis by activation of Ca2+-dependent protein kinase C-alpha

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gamma-Aminobutyric acid inhibits cholangiocarcinoma growth by cyclic AMP-dependent regulation of the protein kinase A/extracellular signal-regulated kinase 1/2 pathway

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21 January 2018

Endothelin inhibits cholangiocarcinoma growth by a decrease in the vascular endothelial growth factor expression

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21 January 2018

The endocannabinoid anandamide inhibits cholangiocarcinoma growth via activation of the noncanonical Wnt signaling pathway

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21 January 2018

Anandamide exerts its antiproliferative actions on cholangiocarcinoma by activation of the GPR55 receptor

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21 January 2018

H3 histamine receptor-mediated activation of protein kinase Calpha inhibits the growth of cholangiocarcinoma in vitro and in vivo.

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21 January 2018

The H4 histamine receptor agonist, clobenpropit, suppresses human cholangiocarcinoma progression by disruption of epithelial mesenchymal transition and tumor metastasis

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21 January 2018

Inhibition of histidine decarboxylase ablates the autocrine tumorigenic effects of histamine in human cholangiocarcinoma

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21 January 2018

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21 January 2018

Detection of response-predicting mutations in the kinase domain of the epidermal growth factor receptor gene in cholangiocarcinomas

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21 January 2018

Amplification and overexpression of c-erbB-2, epidermal growth factor receptor, and c-met in biliary tract cancers

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Prognostic significance of overexpression of c-Met oncoprotein in cholangiocarcinoma

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Immunohistochemical demonstration of MET overexpression in human intrahepatic cholangiocarcinoma and in hepatolithiasis

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

EGF/EGFR axis contributes to the progression of cholangiocarcinoma through the induction of an epithelial-mesenchymal transition.

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Overexpression of epithelial-mesenchymal transition-related markers according to cell dedifferentiation: clinical implications as an independent predictor of poor prognosis in cholangiocarcinoma

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Nuclear expression of S100A4 calcium-binding protein increases cholangiocarcinoma invasiveness and metastasization

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Involvement of PI3K and ERK1/2 pathways in hepatocyte growth factor-induced cholangiocarcinoma cell invasion

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Bile acids activate EGF receptor via a TGF-alpha-dependent mechanism in human cholangiocyte cell lines

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Impact of bile acids on the growth of human cholangiocarcinoma via FXR.

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Conjugated bile acids promote cholangiocarcinoma cell invasive growth through activation of sphingosine 1-phosphate receptor 2.

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Cholangiocarcinomas can originate from hepatocytes in mice

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Intrahepatic cholangiocarcinoma can arise from Notch-mediated conversion of hepatocytes

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Constitutive Notch2 signaling induces hepatic tumors in mice

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Differential effects of targeting Notch receptors in a mouse model of liver cancer

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

The roles of Notch1 expression in the migration of intrahepatic cholangiocarcinoma

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Inhibition of hedgehog signaling attenuates carcinogenesis in vitro and increases necrosis of cholangiocellular carcinoma.

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Non-canonical Hedgehog signaling contributes to chemotaxis in cholangiocarcinoma

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Myofibroblast-derived PDGF-BB promotes Hedgehog survival signaling in cholangiocarcinoma cells

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Polo-like kinase 2 is a mediator of hedgehog survival signaling in cholangiocarcinoma.

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Desmoplastic stroma and cholangiocarcinoma: clinical implications and therapeutic targeting

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Inhibition of interleukin 6-mediated mitogen-activated protein kinase activation attenuates growth of a cholangiocarcinoma cell line

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Interleukin-6 contributes to growth in cholangiocarcinoma cells by aberrant promoter methylation and gene expression

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Interleukin-6 contributes to Mcl-1 up-regulation and TRAIL resistance via an Akt-signaling pathway in cholangiocarcinoma cells

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Mcl-1 mediates tumor necrosis factor-related apoptosis-inducing ligand resistance in human cholangiocarcinoma cells.

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Interleukin 6 upregulates myeloid cell leukemia-1 expression through a STAT3 pathway in cholangiocarcinoma cells

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Over-expression of interleukin-6 enhances cell survival and transformed cell growth in human malignant cholangiocytes

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Sustained IL-6/STAT-3 signaling in cholangiocarcinoma cells due to SOCS-3 epigenetic silencing

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

In situ detection of TGF betas, TGF beta receptor II mRNA and telomerase activity in rat cholangiocarcinogenesis

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

E/N-cadherin switch mediates cancer progression via TGF-β-induced epithelial-to-mesenchymal transition in extrahepatic cholangiocarcinoma

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Epithelial-mesenchymal transition induced by transforming growth factor-{beta}1/Snail activation aggravates invasive growth of cholangiocarcinoma

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Bile acids induce cyclooxygenase-2 expression via the epidermal growth factor receptor in a human cholangiocarcinoma cell line

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Oxysterols induce cyclooxygenase-2 expression in cholangiocytes: implications for biliary tract carcinogenesis

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Cyclooxygenase-2 and ERBB-2 in cholangiocarcinoma: potential therapeutic targets

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Celecoxib-induced apoptosis in rat cholangiocarcinoma cells mediated by Akt inactivation and Bax translocation

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Cyclooxygenase-2 promotes human cholangiocarcinoma growth: evidence for cyclooxygenase-2-independent mechanism in celecoxib-mediated induction of p21waf1/cip1 and p27kip1 and cell cycle arrest

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Reappraisal of the therapeutic role of celecoxib in cholangiocarcinoma.

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Microsomal prostaglandin E synthase-1 inhibits PTEN and promotes experimental cholangiocarcinogenesis and tumor progression

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Nitric oxide-mediated inhibition of DNA repair potentiates oxidative DNA damage in cholangiocytes

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Inducible nitric oxide synthase upregulates cyclooxygenase-2 in mouse cholangiocytes promoting cell growth

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

IL-33 facilitates oncogene-induced cholangiocarcinoma in mice by an interleukin-6-sensitive mechanism

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Accessories to the crime: functions of cells recruited to the tumor microenvironment

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Influence of tumour micro-environment heterogeneity on therapeutic response

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

The emerging roles of microvesicles in liver diseases

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Human bile contains microRNA-laden extracellular vesicles that can be used for cholangiocarcinoma diagnosis

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Extracellular vesicle noncoding RNA: new players in the diagnosis and pathogenesis of cholangiocarcinoma

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Tumour cell-derived extracellular vesicles interact with mesenchymal stem cells to modulate the microenvironment and enhance cholangiocarcinoma growth

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Molecular profiling of stroma identifies osteopontin as an independent predictor of poor prognosis in intrahepatic cholangiocarcinoma

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Genomic and genetic characterization of cholangiocarcinoma identifies therapeutic targets for tyrosine kinase inhibitors

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

The role of cancer-associated myofibroblasts in intrahepatic cholangiocarcinoma

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Platelet-derived growth factor-D and Rho GTPases regulate recruitment of cancer-associated fibroblasts in cholangiocarcinoma

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Possible regulation of migration of intrahepatic cholangiocarcinoma cells by interaction of CXCR4 expressed in carcinoma cells with tumor necrosis factor-alpha and stromal-derived factor-1 released in stroma

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Role of the stromal-derived factor-1 (SDF-1)-CXCR4 axis in the interaction between hepatic stellate cells and cholangiocarcinoma

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Hepatic myofibroblasts promote the progression of human cholangiocarcinoma through activation of epidermal growth factor receptor.

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Identification of CXCL5/ENA-78 as a factor involved in the interaction between cholangiocarcinoma cells and cancer-associated fibroblasts

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Hedgehog signaling between cancer cells and hepatic stellate cells in promoting cholangiocarcinoma

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Hepatic stellate cells may relate to progression of intrahepatic cholangiocarcinoma

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Therapeutic effects of deleting cancer-associated fibroblasts in cholangiocarcinoma

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Circulating CD14(+) CD16(+) monocyte levels predict tissue invasive character of cholangiocarcinoma.

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Significance of alternatively activated macrophages in patients with intrahepatic cholangiocarcinoma.

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Activated macrophages promote Wnt/β-catenin signaling in cholangiocarcinoma cells

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Tumor-associated angiogenesis and lymphangiogenesis correlate with progression of intrahepatic cholangiocarcinoma

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Prognostic factors in node-negative intrahepatic cholangiocarcinoma with special reference to angiogenesis

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Primary sclerosing cholangitis.

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Cholangiocarcinoma in primary sclerosing cholangitis: risk factors and clinical presentation.

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Cholangiocarcinoma complicating primary sclerosing cholangitis: a 24-year experience

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

The clinical presentation and prognostic factors for intrahepatic and extrahepatic cholangiocarcinoma in a tertiary care centre.

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Cholangiocarcinoma in cirrhosis: absence of contrast washout in delayed phases by magnetic resonance imaging avoids misdiagnosis of hepatocellular carcinoma.

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Contrast enhanced CT-scan to diagnose intrahepatic cholangiocarcinoma in patients with cirrhosis.

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Peripheral mass-forming cholangiocarcinoma in cirrhotic liver.

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Intrahepatic cholangiocarcinoma: expert consensus statement.

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Difficult Diagnostic Problems in Pancreatobiliary Neoplasia.

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

The Ability to Diagnose Intrahepatic Cholangiocarcinoma Definitively Using Novel Branched DNA-Enhanced Albumin RNA In Situ Hybridization Technology

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Biliary stent therapy for dominant strictures in patients affected by primary sclerosing cholangitis

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Magnetic resonance cholangiopancreatography: a meta-analysis of test performance in suspected biliary disease

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

An update on cholangiocarcinoma associated with primary sclerosing cholangitis

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Using CT and cholangiography to diagnose biliary tract carcinoma complicating primary sclerosing cholangitis.

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Diagnosis and management of primary sclerosing cholangitis.

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

EASL Clinical Practice Guidelines: management of cholestatic liver diseases.

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

ACG Clinical Guideline: Primary Sclerosing Cholangitis.

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Comparative effectiveness of biliary brush cytology and intraductal biopsy for detection of malignant biliary strictures: a systematic review and meta-analysis.

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Hilar cholangiocarcinoma: expert consensus statement

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Trans-peritoneal fine needle aspiration biopsy of hilar cholangiocarcinoma is associated with disease dissemination

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

The value of serum CA 19-9 in predicting cholangiocarcinomas in patients with primary sclerosing cholangitis

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Serum and biliary insulin-like growth factor I and vascular endothelial growth factor in determining the cause of obstructive cholestasis.

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Volatile organic compounds in bile for early diagnosis of cholangiocarcinoma in patients with primary sclerosing cholangitis: a pilot study

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Bile proteomics for differentiation of malignant from benign biliary strictures: a pilot study

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Progranulin and cholangiocarcinoma: another bad boy on the block!

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Serum and bile biomarkers for cholangiocarcinoma

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

New staging system and a registry for perihilar cholangiocarcinoma

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Comparison of the sixth and the seventh editions of the UICC classification for perihilar cholangiocarcinoma

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Hilar cholangiocarcinoma

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Evolution of surgical treatment for perihilar cholangiocarcinoma: a single-center 34-year review of 574 consecutive resections

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Liver transplantation for cholangiocarcinoma

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Efficacy of neoadjuvant chemoradiation, followed by liver transplantation, for perihilar cholangiocarcinoma at 12 US centers

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Predictors of pretransplant dropout and posttransplant recurrence in patients with perihilar cholangiocarcinoma

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Cisplatin and gemcitabine for advanced biliary tract cancer: a meta-analysis of two randomised trials

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Cisplatin plus gemcitabine versus gemcitabine for biliary tract cancer

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Gemcitabine alone or in combination with cisplatin in patients with biliary tract cancer: a comparative multicentre study in Japan

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Gemcitabine and oxaliplatin in advanced biliary tract carcinoma: a phase II study

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Gemcitabine and oxaliplatin in patients with unresectable biliary cancer including gall bladder cancer: a Korean Cancer Study Group phase II trial

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Second-line chemotherapy in advanced biliary cancer: a systematic review

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Metformin inhibits tumor growth by regulating multiple miRNAs in human cholangiocarcinoma

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Transarterial chemoembolization versus supportive therapy in the palliative treatment of unresectable intrahepatic cholangiocarcinoma.

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Intra-arterial therapy for advanced intrahepatic cholangiocarcinoma: a multi-institutional analysis.

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Treatment of unresectable cholangiocarcinoma using yttrium-90 microspheres: results from a pilot study

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Comparative effectiveness of hepatic artery based therapies for unresectable intrahepatic cholangiocarcinoma.

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Radiofrequency ablation in the treatment of unresectable intrahepatic cholangiocarcinoma: systematic review and meta-analysis

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Endoscopic radiofrequency ablation for malignant biliary obstruction: a nationwide retrospective study of 84 consecutive applications.

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Successful photodynamic therapy for nonresectable cholangiocarcinoma: a randomized prospective study

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Photodynamic therapy for unresectable cholangiocarcinoma: a comparative effectiveness systematic review and meta-analyses

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Endoscopic stenting for hilar cholangiocarcinoma: efficacy of unilateral and bilateral placement of plastic and metal stents in a retrospective review of 480 patients.

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Molecular pathogenesis of cholangiocarcinoma

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Cholangiocarcinoma: molecular pathways and therapeutic opportunities

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Omega-3 Polyunsaturated Fatty Acids Upregulate 15-PGDH Expression in Cholangiocarcinoma Cells by Inhibiting miR-26a/b Expression

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

miR-21 Inhibition Reduces Liver Fibrosis and Prevents Tumor Development by Inducing Apoptosis of CD24+ Progenitor Cells

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Mouse model of intrahepatic cholangiocarcinoma validates FIG-ROS as a potent fusion oncogene and therapeutic target

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Enhanced antitumour drug delivery to cholangiocarcinoma through the apical sodium-dependent bile acid transporter (ASBT).

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

PD-L1 and HLA Class I Antigen Expression and Clinical Course of the Disease in Intrahepatic Cholangiocarcinoma

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Pharmacogenetics of the organic anion transporting polypeptide 1A2

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Expression of SLC22A1 variants may affect the response of hepatocellular carcinoma and cholangiocarcinoma to sorafenib.

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Concurrent analysis of human equilibrative nucleoside transporter 1 and ribonucleotide reductase subunit 1 expression increases predictive value for prognosis in cholangiocarcinoma patients treated with adjuvant gemcitabine-based chemotherapy

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Characterization of 5-fluorouracil-resistant cholangiocarcinoma cell lines.

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

No correlation between the expression of FXR and genes involved in multidrug resistance phenotype of primary liver tumors.

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Molecular identification and functional characterization of Mdr1a in rat cholangiocytes

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Epithelial secretion of vinblastine by human intestinal adenocarcinoma cell (HCT-8 and T84) layers expressing P-glycoprotein

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Biochemical, cellular, and pharmacological aspects of the multidrug transporter

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Expression of MDR1 mRNA and encoding P-glycoprotein in archival formalin-fixed paraffin-embedded gall bladder cancer tissues

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Expression of the multidrug resistance proteins MRP2 and MRP3 in human cholangiocellular carcinomas

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Increased cytotoxicity and bystander effect of 5-fluorouracil and 5-deoxy-5-fluorouridine in human colorectal cancer cells transfected with thymidine phosphorylase

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Orotate phosphoribosyl transferase mRNA expression and the response of cholangiocarcinoma to 5-fluorouracil

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Reversal of multiple drug resistance in cholangiocarcinoma by the glutathione S-transferase-pi-specific inhibitor O1-hexadecyl-gamma-glutamyl-S-benzylcysteinyl-D-phenylglycine ethylester.

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Drug sensitivity and drug resistance profiles of human intrahepatic cholangiocarcinoma cell lines

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

High expression of thymidylate synthase leads to resistance to 5-fluorouracil in biliary tract carcinoma in vitro

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Simvastatin enhances the chemotherapeutic efficacy of S-1 against bile duct cancer: E2F-1/TS downregulation might be the mechanism

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Expression of IGF-I, IGF-II, and IGF-IR in gallbladder carcinoma. A systematic analysis including primary and corresponding metastatic tumours

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

The therapeutic potential of agents targeting the type I insulin-like growth factor receptor

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Disrupting insulin-like growth factor signaling as a potential cancer therapy

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Enhanced expression of RAD51 associating protein-1 is involved in the growth of intrahepatic cholangiocarcinoma cells

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Prediction of breast cancer sensitivity to neoadjuvant chemotherapy based on status of DNA damage repair proteins

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Promoter hypermethylation is a major event of hMLH1 gene inactivation in liver fluke related cholangiocarcinoma.

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Gene expression analysis for predicting gemcitabine resistance in human cholangiocarcinoma

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Silencing of Tousled-like kinase 1 sensitizes cholangiocarcinoma cells to cisplatin-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Structural and biophysical characterization of the interactions between the death domain of Fas receptor and calmodulin.

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Bcl-2 is overexpressed and alters the threshold for apoptosis in a cholangiocarcinoma cell line

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Acquisition of chemoresistance in intrahepatic cholangiocarcinoma cells by activation of AKT and extracellular signal-regulated kinase (ERK)1/2.

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

XIAP antagonist embelin inhibited proliferation of cholangiocarcinoma cells.

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Pathological spectrum of intrahepatic cholangiocarcinoma arising in non-biliary chronic advanced liver diseases

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Cystic and micropapillary epithelial changes of peribiliary glands might represent a precursor lesion of biliary epithelial neoplasms

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Epithelial cell adhesion molecule is a prognosis marker for intrahepatic cholangiocarcinoma

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Clinicopathologic significance of Sox2, CD44 and CD44v6 expression in intrahepatic cholangiocarcinoma

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Cholangiocarcinoma development: the resurgence of bile acids

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

FUT2 and FUT3 genotype determines CA19-9 cut-off values for detection of cholangiocarcinoma in patients with primary sclerosing cholangitis

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Different relation between ERCC1 overexpression and treatment outcomes of two platinum agents in advanced biliary tract adenocarcinoma patients

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Liver transplantation for cholangiocarcinoma: Selection is essential for acceptable results

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

21 January 2018

Molecular Bases of Chemoresistance in Cholangiocarcinoma

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

31 March 2020

Prognostic significance of tumor doubling time in mass-forming type cholangiocarcinoma

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

31 March 2020

AJCC 7th edition of TNM staging accurately discriminates outcomes of patients with resectable intrahepatic cholangiocarcinoma: By the AFC-IHCC-2009 study group

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

31 March 2020

Intrahepatic calculi associated with cholangiocarcinoma

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

31 March 2020

Cystic and papillary neoplasm involving peribiliary glands: a biliary counterpart of branch-type intraductal papillary mucinous [corrected] neoplasm?

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

31 March 2020

Mucin-producing cholangiocarcinoma might derive from biliary tree stem/progenitor cells located in peribiliary glands

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

31 March 2020

Cholangiocarcinoma: a cancer in search of the right classification

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

31 March 2020

Association of stem cell marker expression pattern and survival in human biliary tract cancer

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

31 March 2020

Exome sequencing of liver fluke-associated cholangiocarcinoma

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

31 March 2020

Global DNA methylation and hydroxymethylation differ in hepatocellular carcinoma and cholangiocarcinoma and relate to survival rate

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

31 March 2020

Endogenous Opioids Modulate the Growth of the Biliary Tree in the Course of Cholestasis

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

31 March 2020

Notch1 is overexpressed in human intrahepatic cholangiocarcinoma and is associated with its proliferation, invasiveness and sensitivity to 5-fluorouracil in vitro

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

31 March 2020

Biliary tract. A new mouse model that closely resembles human cholangiocarcinoma

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

31 March 2020

Microvessel density correlates with lymph node metastases and prognosis in hilar cholangiocarcinoma

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

31 March 2020

Cholangiocarcinoma in young individuals with and without primary sclerosing cholangitis

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

31 March 2020

Cytokeratin 7 and 20 expression in cholangiocarcinomas varies along the biliary tract but still differs from that in colorectal carcinoma metastasis

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

31 March 2020

Comparative immunohistochemical profile of hepatocellular carcinoma, cholangiocarcinoma, and metastatic adenocarcinoma

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

31 March 2020

N-cadherin serves as diagnostic biomarker in intrahepatic and perihilar cholangiocarcinomas

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

31 March 2020

A prospective comparison of the diagnostic accuracy of ERCP, MRCP, CT, and EUS in biliary strictures

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

31 March 2020

Improvement in perioperative and long-term outcome after surgical treatment of hilar cholangiocarcinoma: results of an Italian multicenter analysis of 440 patients

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

31 March 2020

EUS-guided fine-needle aspiration cytodiagnosis of hilar cholangiocarcinoma: a case series

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

31 March 2020

EUS-guided fine-needle aspiration of suspected hilar cholangiocarcinoma in potentially operable patients with negative brush cytology

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

31 March 2020

ERCP or EUS for tissue diagnosis of biliary strictures? A prospective comparative study

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

31 March 2020

Endoscopic ultrasound and fine-needle aspiration of unexplained bile duct strictures

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

31 March 2020

Yield of endoscopic ultrasound-guided fine-needle aspiration of bile duct lesions

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

31 March 2020

Staging, resectability, and outcome in 225 patients with hilar cholangiocarcinoma

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

31 March 2020

Trends in survival after surgery for cholangiocarcinoma: a 30-year population-based SEER database analysis

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

31 March 2020

Surgical outcomes of 230 resected hilar cholangiocarcinoma in a single centre

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

31 March 2020

Can we cure cholangiocarcinoma with neoadjuvant chemoradiation and liver transplantation? Time for a multicenter trial

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

31 March 2020

Cost-effectiveness of gemcitabine + cisplatin vs. gemcitabine monotherapy in advanced biliary tract cancer

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

31 March 2020

Safety and feasibility of endoscopic biliary radiofrequency ablation treatment of extrahepatic cholangiocarcinoma

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

31 March 2020

Efficacy and safety of photodynamic therapy for unresectable cholangiocarcinoma: A meta-analysis

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

31 March 2020

Advances in endoscopic retrograde cholangiopancreatography for the treatment of cholangiocarcinoma

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

31 March 2020

Cost comparison of endoscopic stenting vs surgical treatment for unresectable cholangiocarcinoma

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

31 March 2020

The analysis of organic anion transporting polypeptide (OATP) mRNA and protein patterns in primary and metastatic liver cancer

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

31 March 2020

Downregulation of organic cation transporter 1 (SLC22A1) is associated with tumor progression and reduced patient survival in human cholangiocellular carcinoma

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

31 March 2020

Human equilibrative nucleoside transporter 1 (hENT1) expression is a potential predictive tool for response to gemcitabine in patients with advanced cholangiocarcinoma

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

31 March 2020

Epidermal growth factor receptor dynamics influences response to epidermal growth factor receptor targeted agents

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

31 March 2020

Microsatellite instability and alternative genetic pathway in intrahepatic cholangiocarcinoma

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

31 March 2020

Microsatellite instability in thorotrast-induced human intrahepatic cholangiocarcinoma

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

31 March 2020

NK4 regulates 5-fluorouracil sensitivity in cholangiocarcinoma cells by modulating the intrinsic apoptosis pathway

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

31 March 2020

Expression and antitumor effects of TRAIL in human cholangiocarcinoma

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.51

31 March 2020

Proposal of a new disease concept "biliary diseases with pancreatic counterparts". Anatomical and pathological bases

1 reference

https://pubmed.ncbi.nlm.nih.gov/27095655

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytokines released from activated human macrophages induce epithelial mesenchymal transition markers of cholangiocarcinoma cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/27095655

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tamoxifen-mediated growth inhibition of human cholangiocarcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/27095655

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tissue invasive macrophage density is correlated with prognosis in cholangiocarcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/27095655

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intrahepatic cholangioenteric anastomosis in carcinoma of the hilus of the liver

1 reference

https://pubmed.ncbi.nlm.nih.gov/27095655

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased local dopamine secretion has growth-promoting effects in cholangiocarcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/27095655

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Triptolide sensitizes resistant cholangiocarcinoma cells to TRAIL-induced apoptosis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/27095655

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Angiogenesis in cholangiocellular carcinoma: expression of vascular endothelial growth factor, angiopoietin-1/2, thrombospondin-1 and clinicopathological significance

1 reference

https://pubmed.ncbi.nlm.nih.gov/27095655

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The cyclooxygenase-2 inhibitor celecoxib blocks phosphorylation of Akt and induces apoptosis in human cholangiocarcinoma cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/27095655

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alpha-smooth muscle actin-positive fibroblasts promote biliary cell proliferation and correlate with poor survival in cholangiocarcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/27095655

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical relationship between MDR1 gene and gallbladder cancer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/27095655

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Recent advances on the mechanisms regulating cholangiocyte proliferation and the significance of the neuroendocrine regulation of cholangiocyte pathophysiology

1 reference

https://pubmed.ncbi.nlm.nih.gov/27095655

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inflammatory cytokines induce DNA damage and inhibit DNA repair in cholangiocarcinoma cells by a nitric oxide-dependent mechanism.

1 reference

https://pubmed.ncbi.nlm.nih.gov/27095655

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transforming growth factor beta 1 stimulates vascular endothelial growth factor gene transcription in human cholangiocellular carcinoma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/27095655

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High expression of ABCC1 indicates poor prognosis in intrahepatic cholangiocarcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/27095655

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Different effects of the Notch receptors in liver cancer revealed

1 reference

https://pubmed.ncbi.nlm.nih.gov/27095655

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/NRGASTRO.2016.51

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27095655%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27095655%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

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