(Q39047967)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24309938%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

title

Prognostic and therapeutic relevance of FLIP and procaspase-8 overexpression in non-small cell lung cancer (English)

1 reference

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2 March 2020

1 reference

1

1 reference

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2 March 2020

Darragh G. McArt

3

1 reference

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2 March 2020

Kathy Gately

11

1 reference

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2 March 2020

Izabela Stasik

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24309938%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

author name string

R Hutchinson

2

1 reference

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2 March 2020

N Crawford

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24309938%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

C Holohan

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24309938%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

I Paul

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24309938%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

S Van Schaeybroeck

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24309938%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

M Salto-Tellez

8

1 reference

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2 March 2020

P G Johnston

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24309938%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

D A Fennell

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24309938%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

K O'Byrne

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24309938%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

R Cummins

13

1 reference

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2 March 2020

E Kay

14

1 reference

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2 March 2020

P Hamilton

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24309938%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

D B Longley

17

1 reference

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2 March 2020

language of work or name

1 reference

5 December 2013

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24309938%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

published in

Cell Death and Disease

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24309938%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

volume

4

1 reference

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2 March 2020

page(s)

e951

1 reference

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Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported

2 March 2020

copyright license

start time

1 December 2013

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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The histone deacetylase inhibitor, MS-275 (entinostat), downregulates c-FLIP, sensitizes osteosarcoma cells to FasL, and induces the regression of osteosarcoma lung metastases

9 September 2017

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Translating TRAIL-receptor targeting agents to the clinic.

9 September 2017

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Identification of an acetylation-dependant Ku70/FLIP complex that regulates FLIP expression and HDAC inhibitor-induced apoptosis

9 September 2017

1 reference

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Targeting IAP proteins for therapeutic intervention in cancer

9 September 2017

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Histone deacetylase inhibitors sensitize glioblastoma cells to TRAIL-induced apoptosis by c-myc-mediated downregulation of cFLIP

9 September 2017

1 reference

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Entinostat for treatment of solid tumors and hematologic malignancies

9 September 2017

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Histone deacetylase inhibitors: potential targets responsible for their anti-cancer effect

9 September 2017

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Targeting c-FLIP in cancer

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3877552

Prognostic significance of TRAIL signaling molecules in stage II and III colorectal cancer

9 September 2017

1 reference

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Vorinostat: A novel therapy for the treatment of cutaneous T-cell lymphoma

9 September 2017

1 reference

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Chemical phylogenetics of histone deacetylases

9 September 2017

1 reference

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Carboplatin and Paclitaxel in combination with either vorinostat or placebo for first-line therapy of advanced non-small-cell lung cancer

9 September 2017

1 reference

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Rational combinations using HDAC inhibitors

9 September 2017

1 reference

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Enhancing the apoptotic and therapeutic effects of HDAC inhibitors

9 September 2017

1 reference

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Directing cancer cells to self-destruct with pro-apoptotic receptor agonists

9 September 2017

1 reference

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The TRAIL apoptotic pathway in cancer onset, progression and therapy

9 September 2017

1 reference

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Combination therapy of established cancer using a histone deacetylase inhibitor and a TRAIL receptor agonist

9 September 2017

1 reference

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Diagnosing and exploiting cancer's addiction to blocks in apoptosis

9 September 2017

1 reference

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Phase II trial of the histone deacetylase inhibitor vorinostat (Zolinza, suberoylanilide hydroxamic acid, SAHA) in patients with recurrent and/or metastatic head and neck cancer

9 September 2017

1 reference

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Histone deacetylase inhibitors: overview and perspectives

9 September 2017

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Histone deacetylase inhibitors: molecular mechanisms of action

9 September 2017

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Histone deacetylase inhibitors and the promise of epigenetic (and more) treatments for cancer

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3877552

Phase I study of an oral histone deacetylase inhibitor, suberoylanilide hydroxamic acid, in patients with advanced cancer

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3877552

Phase I clinical trial of histone deacetylase inhibitor: suberoylanilide hydroxamic acid administered intravenously.

9 September 2017

1 reference

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Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes

9 September 2017

1 reference

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First-line chemotherapy for NSCLC: an overview of relevant trials.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3877552

Comparison of four chemotherapy regimens for advanced non-small-cell lung cancer

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3877552

Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors

9 September 2017

1 reference

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Acquired differential regulation of caspase-8 in cisplatin-resistant non-small-cell lung cancer.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3877552

Prognostic and therapeutic relevance of c-FLIP in acute myeloid leukaemia

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3877552

Vorinostat/SAHA-induced apoptosis in malignant mesothelioma is FLIP/caspase 8-dependent and HR23B-independent

9 September 2017

1 reference

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The Ripoptosome, a signaling platform that assembles in response to genotoxic stress and loss of IAPs

9 September 2017

1 reference

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Platinum resistant cancer cells conserve sensitivity to BH3 domains and obatoclax induced mitochondrial apoptosis

9 September 2017

1 reference

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In vitro and in vivo characterisation of a novel c-FLIP-targeted antisense phosphorothioate oligonucleotide

14 September 2017

1 reference

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Procaspase 8 overexpression in non-small-cell lung cancer promotes apoptosis induced by FLIP silencing

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3877552

c-FLIP: a key regulator of colorectal cancer cell death

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3877552

HDAC inhibitor treatment of hepatoma cells induces both TRAIL-independent apoptosis and restoration of sensitivity to TRAIL.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3877552

Expression of TRAIL and TRAIL death receptors in stage III non-small cell lung cancer tumors

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3877552

Differential inactivation of caspase-8 in lung cancers.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3877552

Histone deacetylase inhibition by valproic acid down-regulates c-FLIP/CASH and sensitizes hepatoma cells towards CD95- and TRAIL receptor-mediated apoptosis and chemotherapy.

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3877552

Increased apoptosis in metastatic human colonic adenocarcinomas.

21 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FCDDIS.2013.481

21 January 2018

Identifiers

DOI

10.1038/CDDIS.2013.481

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24309938%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24309938%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

PubMed publication ID

24309938

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24309938%20AND%20SRC:MED&resulttype=core&format=json