(Q24302531)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22266862%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

title

Histone deacetylase inhibitors sensitize glioblastoma cells to TRAIL-induced apoptosis by c-myc-mediated downregulation of cFLIP (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22266862%20AND%20SRC:MED&resulttype=core&format=json

TNF superfamily member 10

20 January 2020

main subject

apoptotic process

0 references

1 reference

CASP8 and FADD like apoptosis regulator

GOA release 2020-03-11

1 reference

positive regulation of extrinsic apoptotic signaling pathway

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

1 reference

Klaus-Michael Debatin

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22266862%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

Simone Fulda

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22266862%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

author name string

A Bangert

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22266862%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

S Cristofanon

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22266862%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

I Eckhardt

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22266862%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

B A Abhari

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22266862%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

S Kolodziej

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22266862%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

S Häcker

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22266862%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

S H K Vellanki

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22266862%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

J Lausen

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22266862%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

language of work or name

English

0 references

publication date

23 January 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22266862%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22266862%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

volume

31

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22266862%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

page(s)

4677-4688

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22266862%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

issue

44

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22266862%20AND%20SRC:MED&resulttype=core&format=json

Exciting new advances in neuro-oncology: the avenue to a cure for malignant glioma

20 January 2020

cites work

1 reference

https://api.crossref.org/works/10.1038/ONC.2011.614

Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

20 April 2017

1 reference

https://api.crossref.org/works/10.1038/ONC.2011.614

The caspase-8 inhibitor FLIP promotes activation of NF-kappaB and Erk signaling pathways

20 April 2017

1 reference

https://api.crossref.org/works/10.1038/ONC.2011.614

The Akt-regulated Forkhead Transcription Factor FOXO3a Controls Endothelial Cell Viability through Modulation of the Caspase-8 Inhibitor FLIP

20 April 2017

1 reference

https://api.crossref.org/works/10.1038/ONC.2011.614

Glycogen synthase kinase-3 inhibition induces glioma cell death through c-MYC, nuclear factor-kappaB, and glucose regulation

20 April 2017

1 reference

https://api.crossref.org/works/10.1038/ONC.2011.614

Cotreatment with histone deacetylase inhibitor LAQ824 enhances Apo-2L/tumor necrosis factor-related apoptosis inducing ligand-induced death inducing signaling complex activity and apoptosis of human acute leukemia cells

20 April 2017

1 reference

https://api.crossref.org/works/10.1038/ONC.2011.614

Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial

20 April 2017

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.614

The biochemistry of apoptosis

20 April 2017

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.614

Mitochondrial membrane permeabilization in cell death

20 April 2017

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.614

Anticancer activities of histone deacetylase inhibitors

20 April 2017

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.614

Histone deacetylase inhibitors and the promise of epigenetic (and more) treatments for cancer

20 April 2017

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.614

New insights into apoptosis signaling by Apo2L/TRAIL.

20 April 2017

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.614

Bcl-2-regulated apoptosis: mechanism and therapeutic potential

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.614

IAP-targeted therapies for cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.614

Directing cancer cells to self-destruct with pro-apoptotic receptor agonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.614

Review: on TRAIL for malignant glioma therapy?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.614

Modulation of TRAIL-induced apoptosis by HDAC inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.614

Epigenetics in cancer: targeting chromatin modifications

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.614

Regulation of E2F1 activity by acetylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.614

The ins and outs of MYC regulation by posttranslational mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.614

Forkhead box-O transcription factor: critical conductors of cancer's fate

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.614

Enhancing the apoptotic and therapeutic effects of HDAC inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.614

NF-kappaB signals induce the expression of c-FLIP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.614

Mitotic arrest and JNK-induced proteasomal degradation of FLIP and Mcl-1 are key events in the sensitization of breast tumor cells to TRAIL by antimicrotubule agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.614

Direct repression of FLIP expression by c-myc is a major determinant of TRAIL sensitivity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.614

E2F1 induces apoptosis and sensitizes human lung adenocarcinoma cells to death-receptor-mediated apoptosis through specific downregulation of c-FLIP(short).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.614

Histone deacetylase inhibitors cooperate with IFN-gamma to restore caspase-8 expression and overcome TRAIL resistance in cancers with silencing of caspase-8.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.614

Butyrate sensitizes human colon cancer cells to TRAIL-mediated apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.614

Depsipeptide (FR901228) induces histone acetylation and inhibition of histone deacetylase in chronic lymphocytic leukemia cells concurrent with activation of caspase 8-mediated apoptosis and down-regulation of c-FLIP protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.614

Sensitization of osteosarcoma cells to death receptor-mediated apoptosis by HDAC inhibitors through downregulation of cellular FLIP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.614

HDAC inhibitor treatment of hepatoma cells induces both TRAIL-independent apoptosis and restoration of sensitivity to TRAIL.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.614

Synthetic lethal targeting of MYC by activation of the DR5 death receptor pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.614

c-Myc primed mitochondria determine cellular sensitivity to TRAIL-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.614

HDAC inhibitors enhance the apoptosis-inducing potential of TRAIL in breast carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.614

Reactivation of death receptor 4 (DR4) expression sensitizes medulloblastoma cell lines to TRAIL.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.614

The histone deacetylase inhibitor suberoylanilide hydroxamic acid sensitises human hepatocellular carcinoma cells to TRAIL-induced apoptosis by TRAIL-DISC activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.614

Enhanced Fas-associated death domain recruitment by histone deacetylase inhibitors is critical for the sensitization of chronic lymphocytic leukemia cells to TRAIL-induced apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.614

Sodium butyrate sensitizes human glioma cells to TRAIL-mediated apoptosis through inhibition of Cdc2 and the subsequent downregulation of survivin and XIAP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.614

DNER, an epigenetically modulated gene, regulates glioblastoma-derived neurosphere cell differentiation and tumor propagation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.614

Experimental therapy of malignant gliomas using the inhibitor of histone deacetylase MS-275.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.614

The benzamide MS-275 is a potent, long-lasting brain region-selective inhibitor of histone deacetylases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.614

Phosphatidylinositol 3-kinase inhibition broadly sensitizes glioblastoma cells to death receptor- and drug-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.614

Monoclonal antibody-mediated tumor regression by induction of apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.614

Identification of a novel pro-apopotic function of NF-kappaB in the DNA damage response

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.614

21 January 2018

Identifiers

DOI

10.1038/ONC.2011.614

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22266862%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

20 January 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22266862%20AND%20SRC:MED&resulttype=core&format=json