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The role of histone modifications and telomere alterations in the pathogenesis of diffuse gliomas in adults and children.
scientific article published on 7 January 2017
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5354997
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5 April 2020
title
The role of histone modifications and telomere alterations in the pathogenesis of diffuse gliomas in adults and children
(English)
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Europe PubMed Central
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5354997
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5 April 2020
corrigendum / erratum
Erratum to: The role of histone modifications and telomere alterations in the pathogenesis of diffuse gliomas in adults and children.
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David A Solomon
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2
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Europe PubMed Central
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5 April 2020
Tarik Tihan
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Tarik Tihan
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5354997
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5 April 2020
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Julieann Lee
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5354997
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5 April 2020
publication date
7 January 2017
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5 April 2020
published in
Journal of Neuro-Oncology
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5354997
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5 April 2020
volume
132
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5 April 2020
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1
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Europe PubMed Central
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5 April 2020
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1-11
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5 April 2020
exact match
https://scigraph.springernature.com/pub.10.1007/s11060-016-2349-9
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Reduced H3K27me3 and DNA hypomethylation are major drivers of gene expression in K27M mutant pediatric high-grade gliomas
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K27M mutation in histone H3.3 defines clinically and biologically distinct subgroups of pediatric diffuse intrinsic pontine gliomas
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IDH mutation impairs histone demethylation and results in a block to cell differentiation
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Somatic histone H3 alterations in pediatric diffuse intrinsic pontine gliomas and non-brainstem glioblastomas
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17 June 2018
Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma
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17 June 2018
Altered telomeres in tumors with ATRX and DAXX mutations
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17 June 2018
The oncometabolite 2-hydroxyglutarate inhibits histone lysine demethylases
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The ATRX-ADD domain binds to H3 tail peptides and reads the combined methylation state of K4 and K9
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17 June 2018
Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases
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17 June 2018
Daxx is an H3.3-specific histone chaperone and cooperates with ATRX in replication-independent chromatin assembly at telomeres
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Covalent histone modifications--miswritten, misinterpreted and mis-erased in human cancers
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17 June 2018
The death-associated protein DAXX is a novel histone chaperone involved in the replication-independent deposition of H3.3
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17 June 2018
Distinct factors control histone variant H3.3 localization at specific genomic regions
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ATRX interacts with H3.3 in maintaining telomere structural integrity in pluripotent embryonic stem cells
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Loss of trimethylation at lysine 27 of histone H3 is a predictor of poor outcome in breast, ovarian, and pancreatic cancers
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Mutations in ATRX, encoding a SWI/SNF-like protein, cause diverse changes in the pattern of DNA methylation
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Diffuse Midline Gliomas with Histone H3-K27M Mutation: A Series of 47 Cases Assessing the Spectrum of Morphologic Variation and Associated Genetic Alterations
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High frequency of H3F3A (K27M) mutations characterizes pediatric and adult high-grade gliomas of the spinal cord.
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TERT promoter mutation and aberrant hypermethylation are associated with elevated expression in medulloblastoma and characterise the majority of non-infant SHH subgroup tumours.
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21 August 2018
TERT promoter mutations rather than methylation are the main mechanism for TERT upregulation in adult gliomas
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21 August 2018
Distribution of TERT promoter mutations in pediatric and adult tumors of the nervous system.
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21 August 2018
The alternative lengthening of telomere phenotype is significantly associated with loss of ATRX expression in high-grade pediatric and adult astrocytomas: a multi-institutional study of 214 astrocytomas
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21 August 2018
Methylation of the TERT promoter and risk stratification of childhood brain tumours: an integrative genomic and molecular study.
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21 August 2018
Hotspot mutations in H3F3A and IDH1 define distinct epigenetic and biological subgroups of glioblastoma.
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21 August 2018
Prognostic significance of overexpression of EZH2 and H3k27me3 proteins in gastric cancer.
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reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5354997
retrieved
21 August 2018
Frequent ATRX mutations and loss of expression in adult diffuse astrocytic tumors carrying IDH1/IDH2 and TP53 mutations
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5354997
retrieved
21 August 2018
ATR-X syndrome protein targets tandem repeats and influences allele-specific expression in a size-dependent manner.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5354997
retrieved
21 August 2018
Polycomb limits the neurogenic competence of neural precursor cells to promote astrogenic fate transition.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5354997
retrieved
21 August 2018
The role of telomere maintenance in the spontaneous growth arrest of pediatric low-grade gliomas
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5354997
retrieved
21 August 2018
Epigenetic regulation of telomere length in mammalian cells by the Suv39h1 and Suv39h2 histone methyltransferases.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5354997
retrieved
21 August 2018
Hypermethylation of the human telomerase catalytic subunit (hTERT) gene correlates with telomerase activity.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5354997
retrieved
21 August 2018
DNA methyltransferases control telomere length and telomere recombination in mammalian cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1007%2FS11060-016-2349-9
retrieved
21 January 2018
Combined analysis of TERT, EGFR, and IDH status defines distinct prognostic glioblastoma classes
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/28064387
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Decreased expression of H3K27me3 in human ovarian carcinomas correlates with more aggressive tumor behavior and poor patient survival
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/28064387
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1007/S11060-016-2349-9
1 reference
stated in
Europe PubMed Central
PMC publication ID
5354997
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28064387%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 April 2020
PMC publication ID
5354997
1 reference
stated in
Europe PubMed Central
PMC publication ID
5354997
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28064387%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 April 2020
PubMed publication ID
28064387
1 reference
stated in
Europe PubMed Central
PMC publication ID
5354997
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28064387%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 April 2020
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