(Q39125363)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16940182%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

title

DNA damage-induced cell cycle regulation and function of novel Chk2 phosphoresidues (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16940182%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

0 references

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16940182%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

Luigi Carlessi

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16940182%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

Laura Zannini

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16940182%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

4

Sofia Lisanti

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16940182%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

7

Domenico Delia

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16940182%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

5

Enrico Fontanella

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16940182%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

author name string

Silvana Canevari

series ordinal

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16940182%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

language of work or name

English

0 references

publication date

28 August 2006

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16940182%20AND%20SRC:MED&resulttype=core&format=json

Molecular and Cellular Biology

29 December 2019

published in

1 reference

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29 December 2019

volume

26

1 reference

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29 December 2019

issue

21

1 reference

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29 December 2019

page(s)

7832-7845

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16940182%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

29 December 2019

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC1636737/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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1 reference

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9 September 2017

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Active role for nibrin in the kinetics of atm activation

9 September 2017

1 reference

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DNA damage-induced phosphorylation of MdmX at serine 367 activates p53 by targeting MdmX for Mdm2-dependent degradation

9 September 2017

1 reference

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ATM and Chk2-dependent phosphorylation of MDMX contribute to p53 activation after DNA damage

9 September 2017

1 reference

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Role of Nbs1 in the activation of the Atm kinase revealed in humanized mouse models

9 September 2017

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ATM activation by DNA double-strand breaks through the Mre11-Rad50-Nbs1 complex

9 September 2017

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Phosphorylation of Hdmx mediates its Hdm2- and ATM-dependent degradation in response to DNA damage

9 September 2017

1 reference

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ATM signaling and genomic stability in response to DNA damage

9 September 2017

1 reference

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Cell-cycle checkpoints and cancer

9 September 2017

1 reference

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The DNA damage response: sensing and signaling

9 September 2017

1 reference

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Distribution and dynamics of chromatin modification induced by a defined DNA double-strand break

9 September 2017

1 reference

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Activation of ATM and Chk2 kinases in relation to the amount of DNA strand breaks.

9 September 2017

1 reference

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ATM and ataxia telangiectasia

9 September 2017

1 reference

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An overview of three new disorders associated with genetic instability: LIG4 syndrome, RS-SCID and ATR-Seckel syndrome

9 September 2017

1 reference

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Ataxia-telangiectasia-like disorder (ATLD)-its clinical presentation and molecular basis

9 September 2017

1 reference

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DNA damage checkpoint kinase Chk2 triggers replicative senescence

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1636737

Apoptosis associated with deregulated E2F activity is dependent on E2F1 and Atm/Nbs1/Chk2.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1636737

Chk2 phosphorylation of BRCA1 regulates DNA double-strand break repair

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1636737

Requirement of the MRN complex for ATM activation by DNA damage

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1636737

Chk1 and Chk2 kinases in checkpoint control and cancer

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1636737

Chk2 activates E2F-1 in response to DNA damage

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1636737

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1636737

DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1636737

PML-dependent apoptosis after DNA damage is regulated by the checkpoint kinase hCds1/Chk2

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1636737

Chk2-deficient mice exhibit radioresistance and defective p53-mediated transcription

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1636737

Phosphorylation of threonine 68 promotes oligomerization and autophosphorylation of the Chk2 protein kinase via the forkhead-associated domain

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1636737

Cell cycle checkpoint signaling through the ATM and ATR kinases

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1636737

Chk2 activation dependence on Nbs1 after DNA damage

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1636737

The ATM-Chk2-Cdc25A checkpoint pathway guards against radioresistant DNA synthesis

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1636737

DNA double-strand breaks: signaling, repair and the cancer connection

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1636737

Requirement for Atr in phosphorylation of Chk1 and cell cycle regulation in response to DNA replication blocks and UV-damaged DNA in Xenopus egg extracts

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1636737

Ataxia telangiectasia-mutated phosphorylates Chk2 in vivo and in vitro

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1636737

ATM protein and p53-serine 15 phosphorylation in ataxia-telangiectasia (AT) patients and at heterozygotes

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1636737

Heterozygous germ line hCHK2 mutations in Li-Fraumeni syndrome

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1636737

Mammalian Chk2 is a downstream effector of the ATM-dependent DNA damage checkpoint pathway

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1636737

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1636737

Linkage of ATM to cell cycle regulation by the Chk2 protein kinase

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1636737

Chk2 activation and phosphorylation-dependent oligomerization

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1636737

DNA damage regulates Chk2 association with chromatin

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1636737

Dual induction of apoptosis and senescence in cancer cells by Chk2 activation: checkpoint activation as a strategy against cancer

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1636737

Seckel syndrome exhibits cellular features demonstrating defects in the ATR-signalling pathway.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1636737

Independent roles for nibrin and Mre11-Rad50 in the activation and function of Atm.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1636737

Checkpoint kinase 2 (Chk2) monomers or dimers phosphorylate Cdc25C after DNA damage regardless of threonine 68 phosphorylation

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1636737

Characterization of tumor-associated Chk2 mutations

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1636737

Dissociation between cell cycle arrest and apoptosis can occur in Li-Fraumeni cells heterozygous for p53 gene mutations.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1636737

Two-step activation of ATM by DNA and the Mre11-Rad50-Nbs1 complex.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1636737

The Mre11/Rad50/Nbs1 complex and its role as a DNA double-strand break sensor for ATM.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1636737

Distinct functional domains of Nbs1 modulate the timing and magnitude of ATM activation after low doses of ionizing radiation

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1636737

DNA damage-induced cell-cycle phase regulation of p53 and p21waf1 in normal and ATM-defective cells

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1636737

Regulation of the Chk2 protein kinase by oligomerization-mediated cis- and trans-phosphorylation

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1636737

The Chk2 tumor suppressor is not required for p53 responses in human cancer cells

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1636737

Threonine 68 is required for radiation-induced phosphorylation and activation of Cds1.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1636737

Inhibition of ATM and ATR kinase activities by the radiosensitizing agent, caffeine.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1636737

Role of human Cds1 (Chk2) kinase in DNA damage checkpoint and its regulation by p53

21 August 2018

1 reference

12 December 2020

Distinct Initiation and Maintenance Mechanisms Cooperate to Induce G1 Cell Cycle Arrest in Response to DNA Damage

1 reference

12 December 2020

Threonine 68 phosphorylation by ataxia telangiectasia mutated is required for efficient activation of Chk2 in response to ionizing radiation

1 reference

12 December 2020

Activation of ataxia telangiectasia mutated by DNA strand break-inducing agents correlates closely with the number of DNA double strand breaks

1 reference

12 December 2020

Identifiers

DOI

10.1128/MCB.00534-06

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16940182%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16940182%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

PubMed publication ID

16940182

1 reference