(Q39414183)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28676700%20AND%20SRC:MED&resulttype=core&format=json

24 March 2020

review article

1 reference

title

The multifaceted roles of PARP1 in DNA repair and chromatin remodelling (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28676700%20AND%20SRC:MED&resulttype=core&format=json

24 March 2020

author name string

Arnab Ray Chaudhuri

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28676700%20AND%20SRC:MED&resulttype=core&format=json

24 March 2020

André Nussenzweig

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28676700%20AND%20SRC:MED&resulttype=core&format=json

24 March 2020

publication date

5 July 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28676700%20AND%20SRC:MED&resulttype=core&format=json

Nature Reviews Molecular Cell Biology

24 March 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28676700%20AND%20SRC:MED&resulttype=core&format=json

24 March 2020

volume

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28676700%20AND%20SRC:MED&resulttype=core&format=json

24 March 2020

issue

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28676700%20AND%20SRC:MED&resulttype=core&format=json

24 March 2020

page(s)

610-621

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28676700%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/nrm.2017.53

24 March 2020

exact match

0 references

cites work

Endogenous DNA Damage as a Source of Genomic Instability in Cancer

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

Synthetic lethality and cancer therapy: lessons learned from the development of PARP inhibitors

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

Resistance to PARP-Inhibitors in Cancer Therapy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

Polypeptide domains of ADP-ribosyltransferase obtained by digestion with plasmin

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

Granzyme B/Perforin-Mediated Apoptosis of Jurkat Cells Results in Cleavage of Poly(ADP-ribose) Polymerase to the 89-kDa Apoptotic Fragment and Less Abundant 64-kDa Fragment

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

Structural Basis for DNA Damage-Dependent Poly(ADP-ribosyl)ation by Human PARP-1

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

31 March 2020

PARP goes transcription

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

Poly(ADP-ribosyl)ation by PARP-1: 'PAR-laying' NAD+ into a nuclear signal

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

Investigation of PARP-1, PARP-2, and PARG interactomes by affinity-purification mass spectrometry

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

Functional interaction between PARP-1 and PARP-2 in chromosome stability and embryonic development in mouse

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

Double-stranded DNA binding domain of poly(ADP-ribose) polymerase-1 and molecular insight into the regulation of its activity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

Proteome-wide identification of poly(ADP-ribose) binding proteins and poly(ADP-ribose)-associated protein complexes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

Proteome-wide identification of poly(ADP-Ribosyl)ation targets in different genotoxic stress responses

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

The diverse biological roles of mammalian PARPS, a small but powerful family of poly-ADP-ribose polymerases.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

Reprogramming cellular events by poly(ADP-ribose)-binding proteins

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

Readers of poly(ADP-ribose): designed to be fit for purpose

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

Poly ADP-ribosylation: a DNA break signal mechanism

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

Poly(ADP-ribose) binds to specific domains of p53 and alters its DNA binding functions

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

Poly(ADP-ribose) binds to specific domains in DNA damage checkpoint proteins

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

Human poly(ADP-ribose) glycohydrolase is expressed in alternative splice variants yielding isoforms that localize to different cell compartments

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

Dual role of poly(ADP-ribose) glycohydrolase in the regulation of cell death in oxidatively stressed A549 cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

Inhibition of poly(ADP-ribose) polymerase-1 or poly(ADP‑ribose) glycohydrolase individually, but not in combination, leads to improved chemotherapeutic efficacy in HeLa cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

Poly(ADP-ribose) polymerase 1 accelerates single-strand break repair in concert with poly(ADP-ribose) glycohydrolase

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

Failure to degrade poly(ADP-ribose) causes increased sensitivity to cytotoxicity and early embryonic lethality

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

Poly(ADP-ribosyl) glycohydrolase prevents the accumulation of unusual replication structures during unperturbed S phase

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

Enhanced DNA accessibility and increased DNA damage induced by the absence of poly(ADP-ribose) hydrolysis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

Single-strand break repair and genetic disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

Role of poly(ADP-ribose) formation in DNA repair

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

An interaction between the mammalian DNA repair protein XRCC1 and DNA ligase III

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

The protein kinase CK2 facilitates repair of chromosomal DNA single-strand breaks

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

Domain specific interaction in the XRCC1-DNA polymerase beta complex

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

XRCC1 stimulates human polynucleotide kinase activity at damaged DNA termini and accelerates DNA single-strand break repair

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

A requirement for PARP-1 for the assembly or stability of XRCC1 nuclear foci at sites of oxidative DNA damage

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

Poly(ADP-ribose) polymerase-2 (PARP-2) is required for efficient base excision DNA repair in association with PARP-1 and XRCC1

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

XRCC1 mutation is associated with PARP1 hyperactivation and cerebellar ataxia

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

ATP for the DNA ligation step in base excision repair is generated from poly(ADP-ribose).

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

ATP-dependent selection between single nucleotide and long patch base excision repair.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

Topoisomerase I inhibitors: camptothecins and beyond

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

Yeast gene for a Tyr-DNA phosphodiesterase that repairs topoisomerase I complexes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

A eukaryotic enzyme that can disjoin dead-end covalent complexes between DNA and type I topoisomerases

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

PARP1-TDP1 coupling for the repair of topoisomerase I-induced DNA damage

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

Enhanced killing of cancer cells by poly(ADP-ribose) polymerase inhibitors and topoisomerase I inhibitors reflects poisoning of both enzymes.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

Base excision repair is impaired in mammalian cells lacking Poly(ADP-ribose) polymerase-1.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

Involvement of poly(ADP-ribose) polymerase in base excision repair

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

Requirement of poly(ADP-ribose) polymerase in recovery from DNA damage in mice and in cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

Cells deficient in PARP-1 show an accelerated accumulation of DNA single strand breaks, but not AP sites, over the PARP-1-proficient cells exposed to MMS.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

Base excision repair is efficient in cells lacking poly(ADP-ribose) polymerase 1.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

PARP is important for genomic stability but dispensable in apoptosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

The PARP inhibitor Olaparib disrupts base excision repair of 5-aza-2'-deoxycytidine lesions

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

Poly (ADP-ribose) polymerase (PARP) is not involved in base excision repair but PARP inhibition traps a single-strand intermediate

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

Disruption of PARP1 function inhibits base excision repair of a sub-set of DNA lesions

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

Understanding nucleotide excision repair and its roles in cancer and ageing.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

The cullin 4B-based UV-damaged DNA-binding protein ligase binds to UV-damaged chromatin and ubiquitinates histone H2A

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

The DDB1-CUL4ADDB2 ubiquitin ligase is deficient in xeroderma pigmentosum group E and targets histone H2A at UV-damaged DNA sites

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

Histone H3 and H4 ubiquitylation by the CUL4-DDB-ROC1 ubiquitin ligase facilitates cellular response to DNA damage

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

PARP1 promotes nucleotide excision repair through DDB2 stabilization and recruitment of ALC1

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

Role of poly(ADP-ribose) polymerase-1 in the removal of UV-induced DNA lesions by nucleotide excision repair

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

DDB2 promotes chromatin decondensation at UV-induced DNA damage

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

Poly(ADP-ribose) contributes to an association between poly(ADP-ribose) polymerase-1 and xeroderma pigmentosum complementation group A in nucleotide excision repair

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

Sources of DNA double-strand breaks and models of recombinational DNA repair

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

Playing the end game: DNA double-strand break repair pathway choice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

Chromatin remodeling at DNA double-strand breaks

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

The zinc-finger domains of PARP1 cooperate to recognize DNA strand breaks

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

PARP-1 mechanism for coupling DNA damage detection to poly(ADP-ribose) synthesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

Dynamics of DNA damage response proteins at DNA breaks: a focus on protein modifications

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

Single molecule detection of PARP1 and PARP2 interaction with DNA strand breaks and their poly(ADP-ribosyl)ation using high-resolution AFM imaging.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

Ataxia telangiectasia mutated (ATM) signaling network is modulated by a novel poly(ADP-ribose)-dependent pathway in the early response to DNA-damaging agents

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

Interaction between ATM and PARP-1 in response to DNA damage and sensitization of ATM deficient cells through PARP inhibition

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

Early embryonic lethality in PARP-1 Atm double-mutant mice suggests a functional synergy in cell proliferation during development

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

PARP1-dependent kinetics of recruitment of MRE11 and NBS1 proteins to multiple DNA damage sites

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

Parp-1 protects homologous recombination from interference by Ku and Ligase IV in vertebrate cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

53BP1 inhibits homologous recombination in Brca1-deficient cells by blocking resection of DNA breaks

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

BRCA1 accelerates CtIP-mediated DNA-end resection

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

Association of BRCA1 with Rad51 in mitotic and meiotic cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

Function of BRCA1 in the DNA damage response is mediated by ADP-ribosylation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

Regulation of DNA double-strand break repair by ubiquitin and ubiquitin-like modifiers.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

3-Aminobenzamide synergistically increases sister-chromatid exchanges in cells exposed to methyl methanesulfonate but not to ultraviolet light

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

Inhibitors of poly(adenosine diphosphate ribose) polymerase induce sister chromatid exchanges

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

Poly(ADP-ribose) polymerase (PARP-1) has a controlling role in homologous recombination

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

Ablation of PARP-1 does not interfere with the repair of DNA double-strand breaks, but compromises the reactivation of stalled replication forks

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

PARP1-driven poly-ADP-ribosylation regulates BRCA1 function in homologous recombination-mediated DNA repair.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

Defective DNA single-strand break repair in spinocerebellar ataxia with axonal neuropathy-1

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

XRCC1 down-regulation in human cells leads to DNA-damaging agent hypersensitivity, elevated sister chromatid exchange, and reduced survival of BRCA2 mutant cells.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

53BP1 loss rescues BRCA1 deficiency and is associated with triple-negative and BRCA-mutated breast cancers

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

Targeting homologous recombination repair defects in cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

High sensitivity of BRCA1-deficient mammary tumors to the PARP inhibitor AZD2281 alone and in combination with platinum drugs

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

Stimulation of the DNA-dependent protein kinase by poly(ADP-ribose) polymerase.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

Visualization of a DNA-PK/PARP1 complex.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

PARP1 and DNA-PKcs synergize to suppress p53 mutation and telomere fusions during T-lineage lymphomagenesis.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

PARP1 Links CHD2-Mediated Chromatin Expansion and H3.3 Deposition to DNA Repair by Non-homologous End-Joining.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

Microhomology-mediated End Joining and Homologous Recombination share the initial end resection step to repair DNA double-strand breaks in mammalian cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

Modernizing the nonhomologous end-joining repertoire: alternative and classical NHEJ share the stage.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

IgH class switching and translocations use a robust non-classical end-joining pathway

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

Ku counteracts mobilization of PARP1 and MRN in chromatin damaged with DNA double-strand breaks.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

Ku regulates the non-homologous end joining pathway choice of DNA double-strand break repair in human somatic cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

The alternative end-joining pathway for repair of DNA double-strand breaks requires PARP1 but is not dependent upon microhomologies

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

PARP-1 and Ku compete for repair of DNA double strand breaks by distinct NHEJ pathways

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

PARP1 is required for chromosomal translocations.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

DNA processing is not required for ATM-mediated telomere damage response after TRF2 deletion

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

Ku70 stimulates fusion of dysfunctional telomeres yet protects chromosome ends from homologous recombination

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

Removal of shelterin reveals the telomere end-protection problem

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

Homologous-recombination-deficient tumours are dependent on Polθ-mediated repair

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

Polymerase θ is a robust terminal transferase that oscillates between three different mechanisms during end-joining

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

Mammalian polymerase θ promotes alternative NHEJ and suppresses recombination

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

The relationship between cell growth, macromolecular synthesis and poly ADP-ribose polymerase in lymphoid cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

PARP is activated at stalled forks to mediate Mre11-dependent replication restart and recombination.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

Functional association of poly(ADP-ribose) polymerase with DNA polymerase alpha-primase complex: a link between DNA strand break detection and DNA replication

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

Regulation of the expression or recruitment of components of the DNA synthesome by poly(ADP-ribose) polymerase

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

Role of the error-free damage bypass postreplication repair pathway in the maintenance of genomic stability

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

The Replication Checkpoint Prevents Two Types of Fork Collapse without Regulating Replisome Stability.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

Topoisomerase I poisoning results in PARP-mediated replication fork reversal

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

PARP-1 ensures regulation of replication fork progression by homologous recombination on damaged DNA.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

Rad51-mediated replication fork reversal is a global response to genotoxic treatments in human cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

Friedreich's ataxia-associated GAA repeats induce replication-fork reversal and unusual molecular junctions

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

Replication fork reversal in eukaryotes: from dead end to dynamic response

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

Oncogenes induce genotoxic stress by mitotic processing of unusual replication intermediates.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

Replication fork reversal and the maintenance of genome stability

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

Human RECQ1 promotes restart of replication forks reversed by DNA topoisomerase I inhibition

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

A short G1 phase imposes constitutive replication stress and fork remodelling in mouse embryonic stem cells.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

Synthetic viability by BRCA2 and PARP1/ARTD1 deficiencies.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

Mre11-dependent degradation of stalled DNA replication forks is prevented by BRCA2 and PARP1

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

Double-strand break repair-independent role for BRCA2 in blocking stalled replication fork degradation by MRE11.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

A distinct replication fork protection pathway connects Fanconi anemia tumor suppressors to RAD51-BRCA1/2.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

Trapping of PARP1 and PARP2 by Clinical PARP Inhibitors

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

Hydroxyurea-stalled replication forks become progressively inactivated and require two different RAD51-mediated pathways for restart and repair.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

Poly(ADP-ribose) polymerase is hyperactivated in homologous recombination-defective cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

Replication fork stability confers chemoresistance in BRCA-deficient cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

PARG is dispensable for recovery from transient replicative stress but required to prevent detrimental accumulation of poly(ADP-ribose) upon prolonged replicative stress

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

Resistance to therapy in BRCA2 mutant cells due to loss of the nucleosome remodeling factor CHD4.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

What histone code for DNA repair?

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

New insights into the molecular and cellular functions of poly(ADP-ribose) and PARPs

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

PARP-1 and gene regulation: progress and puzzles.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

Transcriptional roles of PARP1 in cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

PARP1 ADP-ribosylates lysine residues of the core histone tails

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

Poly(ADP-ribosyl)ation of polynucleosomes causes relaxation of chromatin structure

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

Transgenic CHD1L expression in mouse induces spontaneous tumors

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

Poly(ADP-ribose)-dependent regulation of DNA repair by the chromatin remodeling enzyme ALC1

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

Poly(ADP-ribosyl)ation directs recruitment and activation of an ATP-dependent chromatin remodeler

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

Poly(ADP-ribosyl)ation links the chromatin remodeler SMARCA5/SNF2H to RNF168-dependent DNA damage signaling

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

Essential role for DNA-PK-mediated phosphorylation of NR4A nuclear orphan receptors in DNA double-strand break repair

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

The ATM repair pathway inhibits RNA polymerase I transcription in response to chromosome breaks

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

ATM-dependent chromatin changes silence transcription in cis to DNA double-strand breaks

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

A chromatin localization screen reveals poly (ADP ribose)-regulated recruitment of the repressive polycomb and NuRD complexes to sites of DNA damage

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

Regulation of DNA-damage responses and cell-cycle progression by the chromatin remodelling factor CHD4

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

DNA-Repair Defects and Olaparib in Metastatic Prostate Cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

PARP Inhibitors for the Treatment and Prevention of Breast Cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

The expanding role of poly(ADP-ribose) metabolism: current challenges and new perspectives.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

Poly (ADP-ribose) glycohydrolase (PARG) and its therapeutic potential

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

Structures and Mechanisms of Enzymes Employed in the Synthesis and Degradation of PARP-Dependent Protein ADP-Ribosylation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

Poly(ADP-ribose) (PAR) polymer is a death signal

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

PARG is recruited to DNA damage sites through poly(ADP-ribose)- and PCNA-dependent mechanisms.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

Depletion of the 110-kilodalton isoform of poly(ADP-ribose) glycohydrolase increases sensitivity to genotoxic and endotoxic stress in mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

The structure of human ADP-ribosylhydrolase 3 (ARH3) provides insights into the reversibility of protein ADP-ribosylation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

Identification and characterization of a mammalian 39-kDa poly(ADP-ribose) glycohydrolase

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

Macrodomain-containing proteins are new mono-ADP-ribosylhydrolases.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

Deficiency of terminal ADP-ribose protein glycohydrolase TARG1/C6orf130 in neurodegenerative disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

Reciprocal binding of PARP-1 and histone H1 at promoters specifies transcriptional outcomes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

Transcriptional coactivation of nuclear factor-kappaB-dependent gene expression by p300 is regulated by poly(ADP)-ribose polymerase-1.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

Chemical genetic discovery of PARP targets reveals a role for PARP-1 in transcription elongation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

Transcriptional repression by binding of poly(ADP-ribose) polymerase to promoter sequences

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.53

Poly(ADP-ribose) synthetase. The DNA binding domain and the automodification domain

31 March 2020

1 reference

12 December 2020

Poly(ADP-ribose) polymerase in base excision repair: always engaged, but not essential for DNA damage processing.

1 reference

12 December 2020

Isolation and characterization of a novel oncogene, amplified in liver cancer 1, within a commonly amplified region at 1q21 in hepatocellular carcinoma.

1 reference

12 December 2020

DNA replication and poly(ADP-ribosyl)ation of chromatin

1 reference

12 December 2020

A superfamily of conserved domains in DNA damage-responsive cell cycle checkpoint proteins

1 reference

12 December 2020

Poly (ADP-Ribose) synthetase. Separation and identification of three proteolytic fragments as the substrate-binding domain, the DNA-binding domain, and the automodification domain

1 reference

12 December 2020

Overlapping roles for PARP1 and PARP2 in the recruitment of endogenous XRCC1 and PNKP into oxidized chromatin

1 reference

12 December 2020

Poly(ADP-ribosyl)ation reactions in the regulation of nuclear functions

1 reference

12 December 2020

Identifiers

DOI

10.1038/NRM.2017.53

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28676700%20AND%20SRC:MED&resulttype=core&format=json

24 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28676700%20AND%20SRC:MED&resulttype=core&format=json

24 March 2020

1 reference