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Epigenetic plasticity and the hallmarks of cancer.
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Europe PubMed Central
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5940341
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28729483%20AND%20SRC:MED&resulttype=core&format=json
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25 March 2020
title
Epigenetic plasticity and the hallmarks of cancer
(English)
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Europe PubMed Central
PMCID
5940341
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28729483%20AND%20SRC:MED&resulttype=core&format=json
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25 March 2020
author
William A Flavahan
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1
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Europe PubMed Central
PMCID
5940341
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28729483%20AND%20SRC:MED&resulttype=core&format=json
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25 March 2020
Bradley Bernstein
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3
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Europe PubMed Central
PMCID
5940341
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28729483%20AND%20SRC:MED&resulttype=core&format=json
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25 March 2020
author name string
Elizabeth Gaskell
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2
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Europe PubMed Central
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5940341
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25 March 2020
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English
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publication date
1 July 2017
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Europe PubMed Central
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5940341
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25 March 2020
published in
Science
1 reference
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Europe PubMed Central
PMCID
5940341
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28729483%20AND%20SRC:MED&resulttype=core&format=json
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25 March 2020
volume
357
1 reference
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Europe PubMed Central
PMCID
5940341
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28729483%20AND%20SRC:MED&resulttype=core&format=json
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25 March 2020
issue
6348
1 reference
stated in
Europe PubMed Central
PMCID
5940341
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25 March 2020
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17 June 2018
Epigenetic reprogramming in cancer
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Inhibition of PRC2 activity by a gain-of-function H3 mutation found in pediatric glioblastoma
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Occupying Chromatin: Polycomb Mechanisms for Getting to Genomic Targets, Stopping Transcriptional Traffic, and Staying Put
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5940341
retrieved
17 June 2018
The Warburg effect dictates the mechanism of butyrate-mediated histone acetylation and cell proliferation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5940341
retrieved
17 June 2018
EZH2 inhibition as a therapeutic strategy for lymphoma with EZH2-activating mutations
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5940341
retrieved
17 June 2018
Cancer genetics and epigenetics: two sides of the same coin?
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5940341
retrieved
17 June 2018
Cancer epigenetics: from mechanism to therapy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5940341
retrieved
17 June 2018
Functions of DNA methylation: islands, start sites, gene bodies and beyond
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5940341
retrieved
17 June 2018
Spatial partitioning of the regulatory landscape of the X-inactivation centre
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5940341
retrieved
17 June 2018
Chromatin-modifying enzymes as modulators of reprogramming
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5940341
retrieved
17 June 2018
Somatic histone H3 alterations in pediatric diffuse intrinsic pontine gliomas and non-brainstem glioblastomas
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5940341
retrieved
17 June 2018
Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5940341
retrieved
17 June 2018
Embryonic stem cell-specific signatures in cancer: insights into genomic regulatory networks and implications for medicine
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5940341
retrieved
17 June 2018
A decade of exploring the cancer epigenome - biological and translational implications
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5940341
retrieved
17 June 2018
Altered telomeres in tumors with ATRX and DAXX mutations
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5940341
retrieved
17 June 2018
Increased methylation variation in epigenetic domains across cancer types
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5940341
retrieved
17 June 2018
CpG island methylation in colorectal cancer: past, present and future
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5940341
retrieved
17 June 2018
Hallmarks of Cancer: The Next Generation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5940341
retrieved
17 June 2018
Chromatin states in pluripotent, differentiated, and reprogrammed cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5940341
retrieved
17 June 2018
Somatic mutations at EZH2 Y641 act dominantly through a mechanism of selectively altered PRC2 catalytic activity, to increase H3K27 trimethylation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5940341
retrieved
17 June 2018
Coordinated activities of wild-type plus mutant EZH2 drive tumor-associated hypertrimethylation of lysine 27 on histone H3 (H3K27) in human B-cell lymphomas
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5940341
retrieved
17 June 2018
Re-expression of CXCL14, a common target for epigenetic silencing in lung cancer, induces tumor necrosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5940341
retrieved
17 June 2018
A chromatin-mediated reversible drug-tolerant state in cancer cell subpopulations
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5940341
retrieved
17 June 2018
Epimutations and cancer predisposition: importance and mechanisms
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5940341
retrieved
17 June 2018
Chromatin structure and the inheritance of epigenetic information
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5940341
retrieved
17 June 2018
Role of the polycomb protein EED in the propagation of repressive histone marks
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5940341
retrieved
17 June 2018
Epigenetic silencing of death receptor 4 mediates tumor necrosis factor-related apoptosis-inducing ligand resistance in gliomas
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5940341
retrieved
17 June 2018
IDH1 and IDH2 mutations in gliomas
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5940341
retrieved
17 June 2018
VHL gene mutations in renal cell carcinoma: role as a biomarker of disease outcome and drug efficacy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5940341
retrieved
17 June 2018
An integrated genomic analysis of human glioblastoma multiforme
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5940341
retrieved
17 June 2018
Tenets of PTEN tumor suppression
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5940341
retrieved
17 June 2018
Epigenetics in cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5940341
retrieved
17 June 2018
Genome-wide maps of chromatin state in pluripotent and lineage-committed cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5940341
retrieved
17 June 2018
The epigenomics of cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5940341
retrieved
17 June 2018
VEGF as a key mediator of angiogenesis in cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5940341
retrieved
17 June 2018
Suppression of Polycomb group proteins by JNK signalling induces transdetermination in Drosophila imaginal discs
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5940341
retrieved
17 June 2018
MGMT promoter methylation and field defect in sporadic colorectal cancer.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5940341
retrieved
17 June 2018
Transposable elements: targets for early nutritional effects on epigenetic gene regulation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5940341
retrieved
17 June 2018
Tumor-associated zinc finger mutations in the CTCF transcription factor selectively alter tts DNA-binding specificity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5940341
retrieved
17 June 2018
The Hallmarks of Cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5940341
retrieved
17 June 2018
BRD4 Regulates Breast Cancer Dissemination through Jagged1/Notch1 Signaling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5940341
retrieved
21 August 2018
Non-genetic heterogeneity--a mutation-independent driving force for the somatic evolution of tumours.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5940341
retrieved
21 August 2018
Recurrent epimutation of SDHC in gastrointestinal stromal tumors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5940341
retrieved
2 December 2018
Molecular biology. Genetic events that shape the cancer epigenome
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/28729483
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1126/SCIENCE.AAL2380
1 reference
stated in
Europe PubMed Central
PMCID
5940341
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28729483%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 March 2020
PMCID
5940341
1 reference
stated in
Europe PubMed Central
PMCID
5940341
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28729483%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 March 2020
PubMed ID
28729483
1 reference
stated in
Europe PubMed Central
PMCID
5940341
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28729483%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 March 2020
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