(Q39511351)

12 September 2017

title

Functional characterization of EMSY gene amplification in human cancers (English)

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12 September 2017

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12 September 2017

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Jorge S Reis-Filho

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12 September 2017

Rachael Natrajan

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Alan Ashworth

series ordinal

10

object named as

Alan Ashworth

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12 September 2017

5

Maryou B Lambros

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12 September 2017

7

Jessica Frankum

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12 September 2017

1

Paul M Wilkerson

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12 September 2017

2

Konstantin J Dedes

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12 September 2017

3

Daniel Wetterskog

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12 September 2017

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Marthe Mansour

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12 September 2017

Alan Mackay

4

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12 September 2017

publication date

7 July 2011

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12 September 2017

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12 September 2017

volume

225

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12 September 2017

issue

1

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12 September 2017

page(s)

29-42

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Focal amplification and oncogene dependency of GAB2 in breast cancer

12 September 2017

cites work

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CCND1 amplification and cyclin D1 expression in breast cancer and their relation with proteomic subgroups and patient outcome

21 January 2018

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Co-amplified genes at 8p12 and 11q13 in breast tumors cooperate with two major pathways in oncogenesis

21 January 2018

1 reference

Cortactin gene amplification and expression in breast cancer: a chromogenic in situ hybridisation and immunohistochemical study

21 January 2018

1 reference

EMSY links the BRCA2 pathway to sporadic breast and ovarian cancer

21 January 2018

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Co-amplification of CCND1 and EMSY is associated with an adverse outcome in ER-positive tamoxifen-treated breast cancers.

21 January 2018

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Amplification of EMSY, a novel oncogene on 11q13, in high grade ovarian surface epithelial carcinomas

21 January 2018

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Genetic alterations of CCND1 and EMSY in breast cancers

21 January 2018

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Crystal structure of the ENT domain of human EMSY.

21 January 2018

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Identification and characterization of a novel nuclear protein complex involved in nuclear hormone receptor-mediated gene regulation.

21 January 2018

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Genomic instability of human mammary epithelial cells overexpressing a truncated form of EMSY.

21 January 2018

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Indicators of homologous recombination deficiency in breast cancer and association with response to neoadjuvant chemotherapy.

21 January 2018

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Gene expression profile of BRCAness that correlates with responsiveness to chemotherapy and with outcome in patients with epithelial ovarian cancer.

21 January 2018

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Genomic profiling of breast tumours in relation to BRCA abnormalities and phenotypes

21 January 2018

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EMSY overexpression disrupts the BRCA2/RAD51 pathway in the DNA-damage response: implications for chromosomal instability/recombination syndromes as checkpoint diseases

21 January 2018

1 reference

Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy

21 January 2018

1 reference

BRCA1 and BRCA2: chemosensitivity, treatment outcomes and prognosis

21 January 2018

1 reference

Recommendation of short tandem repeat profiling for authenticating human cell lines, stem cells, and tissues

21 January 2018

1 reference

Short tandem repeat profiling: part of an overall strategy for reducing the frequency of cell misidentification

21 January 2018

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The genomic profile of HER2-amplified breast cancers: the influence of ER status

21 January 2018

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Tiling path genomic profiling of grade 3 invasive ductal breast cancers

21 January 2018

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Mucinous carcinoma of the breast is genomically distinct from invasive ductal carcinomas of no special type

21 January 2018

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Molecular analysis reveals a genetic basis for the phenotypic diversity of metaplastic breast carcinomas

21 January 2018

1 reference

Resolving the resolution of array CGH.

21 January 2018

1 reference

Getting it right: designing microarray (and not 'microawry') comparative genomic hybridization studies for cancer research

21 January 2018

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A high-resolution integrated analysis of genetic and expression profiles of breast cancer cell lines

21 January 2018

1 reference

An integrative genomic and transcriptomic analysis reveals molecular pathways and networks regulated by copy number aberrations in basal-like, HER2 and luminal cancers

21 January 2018

1 reference

Triple negative tumours: a critical review

21 January 2018

1 reference

Unlocking pathology archives for molecular genetic studies: a reliable method to generate probes for chromogenic and fluorescent in situ hybridization

21 January 2018

1 reference

Does chromosome 17 centromere copy number predict polysomy in breast cancer? A fluorescence in situ hybridization and microarray-based CGH analysis

21 January 2018

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Absolute quantification of mRNA using real-time reverse transcription polymerase chain reaction assays

21 January 2018

1 reference

Validation of endogenous controls for gene expression analysis in microdissected human renal biopsies

21 January 2018

1 reference

PPM1D gene amplification and overexpression in breast cancer: a qRT-PCR and chromogenic in situ hybridization study

21 January 2018

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Neuroprotection by minocycline caused by direct and specific scavenging of peroxynitrite

21 January 2018

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A synthetic lethal siRNA screen identifying genes mediating sensitivity to a PARP inhibitor

21 January 2018

1 reference

Parallel RNAi and compound screens identify the PDK1 pathway as a target for tamoxifen sensitization

21 January 2018

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Integrated functional, gene expression and genomic analysis for the identification of cancer targets

21 January 2018

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Parallel high-throughput RNA interference screens identify PINK1 as a potential therapeutic target for the treatment of DNA mismatch repair-deficient cancers

21 January 2018

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PTEN deficiency in endometrioid endometrial adenocarcinomas predicts sensitivity to PARP inhibitors

21 January 2018

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Synthetic lethal targeting of PTEN mutant cells with PARP inhibitors

21 January 2018

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21 January 2018

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Genome maintenance mechanisms for preventing cancer

21 January 2018

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Resistance to therapy caused by intragenic deletion in BRCA2

21 January 2018

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Synergistic chemosensitivity of triple-negative breast cancer cell lines to poly(ADP-Ribose) polymerase inhibition, gemcitabine, and cisplatin

21 January 2018

1 reference

Characterization of the recurrent 8p11-12 amplicon identifies PPAPDC1B, a phosphatase protein, as a new therapeutic target in breast cancer

21 January 2018

1 reference

DNA amplifications in breast cancer: genotypic-phenotypic correlations

21 January 2018

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Elevated recombination in immortal human cells is mediated by HsRAD51 recombinase

21 January 2018

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Characterization of BRCA2: temperature sensitivity of detection and cell-cycle regulated expression

21 January 2018

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PPM1D is a potential therapeutic target in ovarian clear cell carcinomas

21 January 2018

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The relationship between the roles of BRCA genes in DNA repair and cancer predisposition

21 January 2018

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BRCA2 is required for homology-directed repair of chromosomal breaks

21 January 2018

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Mutation in Brca2 stimulates error-prone homology-directed repair of DNA double-strand breaks occurring between repeated sequences

21 January 2018

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Therapeutic exploitation of tumor cell defects in homologous recombination

21 January 2018

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Selective inhibition of BRCA2-deficient mammary tumor cell growth by AZD2281 and cisplatin.

21 January 2018

1 reference

Oral poly(ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and advanced breast cancer: a proof-of-concept trial

21 January 2018

1 reference

Oral poly(ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and recurrent ovarian cancer: a proof-of-concept trial

21 January 2018

1 reference

Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase

21 January 2018

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High sensitivity of BRCA1-deficient mammary tumors to the PARP inhibitor AZD2281 alone and in combination with platinum drugs

21 January 2018

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Inhibition of poly(ADP-ribose) polymerase in tumors from BRCA mutation carriers

21 January 2018

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Essential role for nuclear PTEN in maintaining chromosomal integrity

21 January 2018

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Personalizing cancer treatment in the age of global genomic analyses: PALB2 gene mutations and the response to DNA damaging agents in pancreatic cancer

21 January 2018

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Cooperation of breast cancer proteins PALB2 and piccolo BRCA2 in stimulating homologous recombination

21 January 2018

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Hallmarks of 'BRCAness' in sporadic cancers

21 January 2018

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A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes

21 January 2018

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Amplification of the BRCA2 Pathway Gene EMSY in Sporadic Breast Cancer Is Related to Negative Outcome

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/PATH.2944

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12 September 2017

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