(Q39845790)

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Aberrant de novo methylation of the p16INK4A CpG island is initiated post gene silencing in association with chromatin remodelling and mimics nucleosome positioning

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Europe PubMed Central

PubMed publication ID

15 September 2017

Aberrant de novo methylation of the p16INK4A CpG island is initiated post gene silencing in association with chromatin remodelling and mimics nucleosome positioning (English)

1 reference

Europe PubMed Central

PubMed publication ID

15 September 2017

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Roger R Reddel

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Europe PubMed Central

PubMed publication ID

15 September 2017

8

object named as

Susan J Clark

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Europe PubMed Central

PubMed publication ID

15 September 2017

author name string

Rebecca A Hinshelwood

1

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Europe PubMed Central

PubMed publication ID

15 September 2017

John R Melki

2

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Europe PubMed Central

PubMed publication ID

15 September 2017

Lily I Huschtscha

3

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Europe PubMed Central

PubMed publication ID

15 September 2017

Cheryl Paul

4

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Europe PubMed Central

PubMed publication ID

15 September 2017

Jenny Z Song

5

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Europe PubMed Central

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15 September 2017

Clare Stirzaker

6

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Europe PubMed Central

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15 September 2017

publication date

28 May 2009

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Europe PubMed Central

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15 September 2017

Human Molecular Genetics

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Europe PubMed Central

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15 September 2017

18

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Europe PubMed Central

PubMed publication ID

15 September 2017

16

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Europe PubMed Central

PubMed publication ID

15 September 2017

3098-3109

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Europe PubMed Central

PubMed publication ID

15 September 2017

Chromatin Structure: A Repeating Unit of Histones and DNA

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP251

21 January 2018

Dynamic regulation of nucleosome positioning in the human genome

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP251

21 January 2018

The role of chromatin during transcription

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP251

21 January 2018

Aberrant patterns of DNA methylation, chromatin formation and gene expression in cancer

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP251

21 January 2018

DNA methylation and gene silencing in cancer

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP251

21 January 2018

Overview of cancer epigenetics

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP251

21 January 2018

Cancer epigenetics: modifications, screening, and therapy

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP251

21 January 2018

CpG islands in vertebrate genomes

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP251

21 January 2018

CpG-rich islands and the function of DNA methylation

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP251

21 January 2018

Progressive region-specific de novo methylation of the p16 CpG island in primary human mammary epithelial cell strains during escape from M(0) growth arrest

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP251

21 January 2018

DNA methylation and gene silencing in cancer: which is the guilty party?

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP251

21 January 2018

The INK4a/ARF network in tumour suppression

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP251

21 January 2018

p16(MTS-1/CDKN2/INK4a) in cancer progression

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP251

21 January 2018

Aberrant methylation of p16(INK4a) is an early event in lung cancer and a potential biomarker for early diagnosis

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP251

21 January 2018

In situ detection of the hypermethylation-induced inactivation of the p16 gene as an early event in oncogenesis

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP251

21 January 2018

Inactivation of p16 in human mammary epithelial cells by CpG island methylation

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP251

21 January 2018

Increased p16 expression with first senescence arrest in human mammary epithelial cells and extended growth capacity with p16 inactivation

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP251

21 January 2018

Normal human mammary epithelial cells spontaneously escape senescence and acquire genomic changes

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP251

21 January 2018

Histologically normal human mammary epithelia with silenced p16(INK4a) overexpress COX-2, promoting a premalignant program

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP251

21 January 2018

Serum-free growth of human mammary epithelial cells: rapid clonal growth in defined medium and extended serial passage with pituitary extract

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP251

21 January 2018

Induction of transformation and continuous cell lines from normal human mammary epithelial cells after exposure to benzo[a]pyrene

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP251

21 January 2018

Loss of chromosomal integrity in human mammary epithelial cells subsequent to escape from senescence

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP251

21 January 2018

Genetic and epigenetic changes in mammary epithelial cells may mimic early events in carcinogenesis

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP251

21 January 2018

Concordant epigenetic silencing of transforming growth factor-beta signaling pathway genes occurs early in breast carcinogenesis.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP251

21 January 2018

Footprinting of mammalian promoters: use of a CpG DNA methyltransferase revealing nucleosome positions at a single molecule level

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP251

21 January 2018

Breast cancer epigenetics: normal human mammary epithelial cells as a model system

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP251

21 January 2018

Altered methylation patterns in cancer cell genomes: cause or consequence?

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP251

21 January 2018

Histone modifications and silencing prior to DNA methylation of a tumor suppressor gene.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP251

21 January 2018

In vitro methylation of the hamster adenine phosphoribosyltransferase gene inhibits its expression in mouse L cells

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP251

21 January 2018

Effect of in vitro DNA methylation on beta-globin gene expression

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP251

21 January 2018

Transcriptional gene silencing promotes DNA hypermethylation through a sequential change in chromatin modifications in cancer cells.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP251

21 January 2018

Constitutive nucleosome depletion and ordered factor assembly at the GRP78 promoter revealed by single molecule footprinting

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP251

21 January 2018

Genome-scale profiling of histone H3.3 replacement patterns.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP251

21 January 2018

Role of nucleosomal occupancy in the epigenetic silencing of the MLH1 CpG island.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP251

21 January 2018

A stem cell-like chromatin pattern may predispose tumor suppressor genes to DNA hypermethylation and heritable silencing

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP251

21 January 2018

Epigenetic stem cell signature in cancer

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP251

21 January 2018

Effects of simian virus 40 T-antigens on normal human mammary epithelial cells reveal evidence for spontaneous alterations in addition to loss of p16(INK4a) expression.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP251

21 January 2018

Methylation sequencing from limiting DNA: embryonic, fixed, and microdissected cells

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP251

21 January 2018

High sensitivity mapping of methylated cytosines

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP251

21 January 2018

Epigenetic remodeling in colorectal cancer results in coordinate gene suppression across an entire chromosome band.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP251

21 January 2018

Identifiers

10.1093/HMG/DDP251

1 reference

Europe PubMed Central

PubMed publication ID

15 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

15 September 2017

ResearchGate publication ID

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