(Q39970150)

English

Tyrosine 302 in RACK1 is essential for insulin-like growth factor-I-mediated competitive binding of PP2A and beta1 integrin and for tumor cell proliferation and migration

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scholarly article

1 reference

Europe PubMed Central

16 September 2017

Tyrosine 302 in RACK1 is essential for insulin-like growth factor-I-mediated competitive binding of PP2A and beta1 integrin and for tumor cell proliferation and migration (English)

1 reference

Europe PubMed Central

16 September 2017

1 reference

based on heuristic

inferred from title

Miles D. Houslay

4

1 reference

Europe PubMed Central

16 September 2017

Rosemary O'Connor

object named as

Rosemary O'Connor

5

0 references

author name string

Patrick A Kiely

1

1 reference

Europe PubMed Central

16 September 2017

George S Baillie

2

1 reference

Europe PubMed Central

16 September 2017

Martin J Lynch

3

1 reference

Europe PubMed Central

16 September 2017

language of work or name

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publication date

19 June 2008

1 reference

Europe PubMed Central

16 September 2017

number of pages

10

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Journal of Biological Chemistry

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Europe PubMed Central

16 September 2017

283

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Europe PubMed Central

16 September 2017

34

1 reference

Europe PubMed Central

16 September 2017

22952-22961

1 reference

Europe PubMed Central

16 September 2017

The RACK1 scaffold protein: a dynamic cog in cell response mechanisms

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800802200

21 January 2018

RACK1 has the nerve to act: structure meets function in the nervous system.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800802200

21 January 2018

Regulation of eukaryotic translation by the RACK1 protein: a platform for signalling molecules on the ribosome

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800802200

21 January 2018

RACK1, an insulin-like growth factor I (IGF-I) receptor-interacting protein, modulates IGF-I-dependent integrin signaling and promotes cell spreading and contact with extracellular matrix

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800802200

21 January 2018

Rack1, a receptor for activated protein kinase C, interacts with integrin beta subunit

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800802200

21 January 2018

RACK1 targets the extracellular signal-regulated kinase/mitogen-activated protein kinase pathway to link integrin engagement with focal adhesion disassembly and cell motility

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800802200

21 January 2018

RACK1 is an insulin-like growth factor 1 (IGF-1) receptor-interacting protein that can regulate IGF-1-mediated Akt activation and protection from cell death

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800802200

21 January 2018

RACK1-mediated integration of adhesion and insulin-like growth factor I (IGF-I) signaling and cell migration are defective in cells expressing an IGF-I receptor mutated at tyrosines 1250 and 1251.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800802200

21 January 2018

Impaired Shc, Ras, and MAPK activation but normal Akt activation in FL5.12 cells expressing an insulin-like growth factor I receptor mutated at tyrosines 1250 and 1251.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800802200

21 January 2018

Identification of domains of the insulin-like growth factor I receptor that are required for protection from apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800802200

21 January 2018

Replacement of tyrosine 1251 in the carboxyl terminus of the insulin-like growth factor-I receptor disrupts the actin cytoskeleton and inhibits proliferation and anchorage-independent growth

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800802200

21 January 2018

Insulin-like growth factor I controls a mutually exclusive association of RACK1 with protein phosphatase 2A and beta1 integrin to promote cell migration

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800802200

21 January 2018

Polyoma and SV40 proteins differentially regulate PP2A to activate distinct cellular signaling pathways involved in growth control

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800802200

21 January 2018

Impairment of phosphatase 2A contributes to the prolonged MAP kinase phosphorylation in Alzheimer's disease fibroblasts

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800802200

21 January 2018

A PP2A regulatory subunit positively regulates Ras-mediated signaling during Caenorhabditis elegans vulval induction

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800802200

21 January 2018

Protein phosphatase 2A suppresses MAP kinase signalling and ectopic protein expression

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800802200

21 January 2018

Protein phosphatase 2A negatively regulates insulin's metabolic signaling pathway by inhibiting Akt (protein kinase B) activity in 3T3-L1 adipocytes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800802200

21 January 2018

Protein phosphatase 2A forms a molecular complex with Shc and regulates Shc tyrosine phosphorylation and downstream mitogenic signaling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800802200

21 January 2018

Effect of a null mutation of the insulin-like growth factor I receptor gene on growth and transformation of mouse embryo fibroblasts

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800802200

21 January 2018

The SPOT-synthesis technique. Synthetic peptide arrays on membrane supports--principles and applications

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800802200

21 January 2018

Mapping binding sites for the PDE4D5 cAMP-specific phosphodiesterase to the N- and C-domains of beta-arrestin using spot-immobilized peptide arrays

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800802200

21 January 2018

Scanning peptide array analyses identify overlapping binding sites for the signalling scaffold proteins, beta-arrestin and RACK1, in cAMP-specific phosphodiesterase PDE4D5.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800802200

21 January 2018

Isoform-selective susceptibility of DISC1/phosphodiesterase-4 complexes to dissociation by elevated intracellular cAMP levels.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800802200

21 January 2018

p75 neurotrophin receptor regulates tissue fibrosis through inhibition of plasminogen activation via a PDE4/cAMP/PKA pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800802200

21 January 2018

1H NMR structural and functional characterisation of a cAMP-specific phosphodiesterase-4D5 (PDE4D5) N-terminal region peptide that disrupts PDE4D5 interaction with the signalling scaffold proteins, beta-arrestin and RACK1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800802200

21 January 2018

The interaction of Src and RACK1 is enhanced by activation of protein kinase C and tyrosine phosphorylation of RACK1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800802200

21 January 2018

RACK1 regulates Src activity and modulates paxillin dynamics during cell migration

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800802200

21 January 2018

RACK1: a novel substrate for the Src protein-tyrosine kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800802200

21 January 2018

The RACK1 signaling scaffold protein selectively interacts with the cAMP-specific phosphodiesterase PDE4D5 isoform

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800802200

21 January 2018

Interaction of protein kinase C with RACK1, a receptor for activated C-kinase: a role in beta protein kinase C mediated signal transduction

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800802200

21 January 2018

Coordinated movement of RACK1 with activated betaIIPKC

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800802200

21 January 2018

Calcineurin promotes hypoxia-inducible factor 1alpha expression by dephosphorylating RACK1 and blocking RACK1 dimerization

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800802200

21 January 2018

Sequence and structure-based prediction of eukaryotic protein phosphorylation sites

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800802200

21 January 2018

Protein phosphatase 2A holoenzyme assembly: identification of contacts between B-family regulatory and scaffolding A subunits

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800802200

21 January 2018

WD40 repeat proteins striatin and S/G(2) nuclear autoantigen are members of a novel family of calmodulin-binding proteins that associate with protein phosphatase 2A

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800802200

21 January 2018

Identifiers

10.1074/JBC.M800802200

1 reference

Europe PubMed Central

16 September 2017

1 reference

Europe PubMed Central

16 September 2017

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