(Q40241191)

English

Transmembrane domains 4, 5, 7, 8, and 10 of the human reduced folate carrier are important structural or functional components of the transmembrane channel for folate substrates

scientific article published on 21 August 2006

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

Transmembrane domains 4, 5, 7, 8, and 10 of the human reduced folate carrier are important structural or functional components of the transmembrane channel for folate substrates (English)

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

transmembrane protein

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1 reference

based on heuristic

inferred from title

author name string

Zhanjun Hou

1

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

Jun Ye

2

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

Christina L Haska

3

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

Larry H Matherly

4

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Europe PubMed Central

PubMed publication ID

18 September 2017

language of work or name

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publication date

21 August 2006

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Europe PubMed Central

PubMed publication ID

18 September 2017

Journal of Biological Chemistry

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Europe PubMed Central

PubMed publication ID

18 September 2017

281

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Europe PubMed Central

PubMed publication ID

18 September 2017

44

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

33588-33596

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

Folic acid: nutritional biochemistry, molecular biology, and role in disease processes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607049200

21 January 2018

The human reduced folate carrier gene is ubiquitously and differentially expressed in normal human tissues: identification of seven non-coding exons and characterization of a novel promoter

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607049200

21 January 2018

Membrane transport of folates

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607049200

21 January 2018

The cellular pharmacology of methotrexate

1 reference

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21 January 2018

Structure and mechanism of the lactose permease of Escherichia coli

1 reference

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21 January 2018

Structure and mechanism of the glycerol-3-phosphate transporter from Escherichia coli

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607049200

21 January 2018

Intracellular trafficking and membrane targeting mechanisms of the human reduced folate carrier in Mammalian epithelial cells.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607049200

21 January 2018

Impaired membrane transport in methotrexate-resistant CCRF-CEM cells involves early translation termination and increased turnover of a mutant reduced folate carrier.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607049200

21 January 2018

Resistance to multiple novel antifolates is mediated via defective drug transport resulting from clustered mutations in the reduced folate carrier gene in human leukaemia cell lines

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607049200

21 January 2018

A mutated murine reduced folate carrier (RFC1) with increased affinity for folic acid, decreased affinity for methotrexate, and an obligatory anion requirement for transport function.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607049200

21 January 2018

A structurally altered human reduced folate carrier with increased folic acid transport mediates a novel mechanism of antifolate resistance.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607049200

21 January 2018

Role of the E45K-reduced folate carrier gene mutation in methotrexate resistance in human leukemia cells.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607049200

21 January 2018

Mutations in the reduced folate carrier gene which confer dominant resistance to 5,10-dideazatetrahydrofolate

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607049200

21 January 2018

Characterization of a mutation in the reduced folate carrier in a transport defective L1210 murine leukemia cell line

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607049200

21 January 2018

Discrimination among reduced folates and methotrexate as transport substrates by a phenylalanine substitution for serine within the predicted eighth transmembrane domain of the reduced folate carrier

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607049200

21 January 2018

Functional role of arginine 373 in substrate translocation by the reduced folate carrier

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607049200

21 January 2018

Localization of a substrate binding domain of the human reduced folate carrier to transmembrane domain 11 by radioaffinity labeling and cysteine-substituted accessibility methods

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607049200

21 January 2018

Acetylcholine receptor channel structure probed in cysteine-substitution mutants.

1 reference

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21 January 2018

Identification of channel-lining residues in the M2 membrane-spanning segment of the GABA(A) receptor alpha1 subunit

1 reference

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21 January 2018

The location of the gate in the acetylcholine receptor channel

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607049200

21 January 2018

Preservation and staining of myelinated nerve fibers.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607049200

21 January 2018

Characterization of a cysteine-less human reduced folate carrier: localization of a substrate-binding domain by cysteine-scanning mutagenesis and cysteine accessibility methods

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607049200

21 January 2018

The region between transmembrane domains 1 and 2 of the reduced folate carrier forms part of the substrate-binding pocket

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607049200

21 January 2018

Analysis of the membrane topology for transmembrane domains 7-12 of the human reduced folate carrier by scanning cysteine accessibility methods

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607049200

21 January 2018

Structural conservation in the major facilitator superfamily as revealed by comparative modeling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607049200

21 January 2018

Antifolate resistance in a HeLa cell line associated with impaired transport independent of the reduced folate carrier.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607049200

21 January 2018

Touring protein fold space with Dali/FSSP

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607049200

21 January 2018

Comparative protein structure modeling of genes and genomes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607049200

21 January 2018

Determining the structure and mechanism of the human multidrug resistance P-glycoprotein using cysteine-scanning mutagenesis and thiol-modification techniques

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607049200

21 January 2018

Structural comparison of lactose permease and the glycerol-3-phosphate antiporter: members of the major facilitator superfamily

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607049200

21 January 2018

Analysis of membrane topology of the human reduced folate carrier protein by hemagglutinin epitope insertion and scanning glycosylation insertion mutagenesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607049200

21 January 2018

Prediction of protein secondary structure at better than 70% accuracy

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607049200

21 January 2018

Identifiers

10.1074/JBC.M607049200

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

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