(Q40494065)

21 September 2017

An automated Genomes-to-Natural Products platform (GNP) for the discovery of modular natural products (English)

1 reference

2-[17-[3-[Formyl(hydroxy)amino]propyl]-16-hydroxy-9-[3-(hydroxyamino)propyl]-12-(1-hydroxyethyl)-6-(hydroxymethyl)-15,21-dimethyl-2,5,8,11,14,19-hexaoxo-1-oxa-4,7,10,13,18-pentazacyclohenicos-3-yl]-2-hydroxyacetic acid

21 September 2017

0 references

Pseudomonas fluorescens

1 reference

1 reference

1 reference

1 reference

2-[9-(3-Aminopropyl)-17-[3-[formyl(hydroxy)amino]propyl]-16-hydroxy-12-(1-hydroxyethyl)-6-(hydroxymethyl)-21-methyl-2,5,8,11,14,19-hexaoxo-1-oxa-4,7,10,13,18-pentazacyclohenicos-3-yl]-2-hydroxyacetic acid

1 reference

[9-(3-aminopropyl)-6-[3-(carbamoylamino)propyl]-19-[1-decanamido-4-(N-hydroxyacetamido)butyl]-3-[3-(N-hydroxyacetamido)propyl]-12-(hydroxymethyl)-18-methyl-2,5,8,11,14,17-hexaoxo-1-oxa-4,7,10,13,16-pentaazacyclononadecan-15-yl](hydroxy)acetic acid

1 reference

FZGZHJMOMMMXAA-GWLNDQIASA-N

1 reference

(11E)-6-{[4-(dimethylamino)-3,5-dihydroxy-6-methyloxan-2-yl]oxy}-14-ethyl-3,5,7,9,13-pentamethyl-1-oxacyclotetradec-11-ene-2,4,10-trione

1 reference

2-[17-[3-[Formyl(hydroxy)amino]propyl]-16-hydroxy-9-[3-(hydroxyamino)propyl]-12-(1-hydroxyethyl)-6-(hydroxymethyl)-21-methyl-2,5,8,11,14,19-hexaoxo-1-oxa-4,7,10,13,18-pentazacyclohenicos-3-yl]-2-hydroxyacetic acid

1 reference

2-[9-(3-Aminopropyl)-17-[3-[formyl(hydroxy)amino]propyl]-16-hydroxy-12-(1-hydroxyethyl)-6-(hydroxymethyl)-15,21-dimethyl-2,5,8,11,14,19-hexaoxo-1-oxa-4,7,10,13,18-pentazacyclohenicos-3-yl]-2-hydroxyacetic acid

1 reference

PQVAQGMYHVAPQH-UHFFFAOYSA-N

1 reference

1 reference

1 reference

1 reference

Michael A Skinnider

2

0 references

Nathan A Magarvey

9

object named as

Nathan A Magarvey

1 reference

21 September 2017

Chad W Johnston

1

1 reference

21 September 2017

Morgan A Wyatt

3

1 reference

21 September 2017

Xiang Li

4

1 reference

21 September 2017

Michael R M Ranieri

5

1 reference

21 September 2017

Lian Yang

6

1 reference

21 September 2017

David L Zechel

7

1 reference

21 September 2017

Bin Ma

8

1 reference

21 September 2017

language of work or name

English

0 references

publication date

28 September 2015

1 reference

full work available at URL

21 September 2017

https://www.nature.com/articles/ncomms9421.pdf

1 reference

19 March 2024

https://api.unpaywall.org/v2/10.1038/ncomms9421?email=unpaywall_01@example.com

published in

Nature Communications

1 reference

21 September 2017

6

1 reference

21 September 2017

8421

1 reference

Creative Commons Attribution 4.0 International

21 September 2017

start time

28 September 2015

1 reference

April 2022 Public Data File from Crossref

0 references

1 reference

19 March 2024

https://api.unpaywall.org/v2/10.1038/ncomms9421?email=unpaywall_01@example.com

access restriction status

open access

1 reference

based on heuristic

inferred from online access status

cites work

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Automated identification of depsipeptide natural products by an informatic search algorithm

22 September 2017

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Pep2Path: automated mass spectrometry-guided genome mining of peptidic natural products

22 September 2017

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22 September 2017

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Structural investigation of ribosomally synthesized natural products by hypothetical structure enumeration and evaluation using tandem MS.

22 September 2017

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Insights into secondary metabolism from a global analysis of prokaryotic biosynthetic gene clusters

22 September 2017

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22 September 2017

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22 September 2017

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Molecular networking as a dereplication strategy

22 September 2017

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Bioinformatic evaluation of the secondary metabolism of antistaphylococcal environmental bacterial isolates

22 September 2017

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MS/MS networking guided analysis of molecule and gene cluster families.

22 September 2017

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22 September 2017

1 reference

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Classification of the adenylation and acyl-transferase activity of NRPS and PKS systems using ensembles of substrate specific hidden Markov models

22 September 2017

1 reference

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Dereplicating nonribosomal peptides using an informatic search algorithm for natural products (iSNAP) discovery.

22 September 2017

1 reference

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Metagenome mining reveals polytheonamides as posttranslationally modified ribosomal peptides

22 September 2017

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New WS9326A congeners from Streptomyces sp. 9078 inhibiting Brugia malayi asparaginyl-tRNA synthetase

22 September 2017

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BioJava: an open-source framework for bioinformatics in 2012

22 September 2017

1 reference

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Mass spectral molecular networking of living microbial colonies

22 September 2017

1 reference

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Bacterial biosynthesis and maturation of the didemnin anti-cancer agents.

22 September 2017

1 reference

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Cryptic polyketide synthase genes in non-pathogenic Clostridium SPP

22 September 2017

1 reference

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SMART 7: recent updates to the protein domain annotation resource

22 September 2017

1 reference

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A mass spectrometry-guided genome mining approach for natural product peptidogenomics

22 September 2017

1 reference

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HMMER web server: interactive sequence similarity searching

22 September 2017

1 reference

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Deciphering the rhizosphere microbiome for disease-suppressive bacteria

22 September 2017

1 reference

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Natural products version 2.0: connecting genes to molecules.

22 September 2017

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Genomic basis for natural product biosynthetic diversity in the actinomycetes

22 September 2017

1 reference

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Drug discovery and natural products: end of an era or an endless frontier?

22 September 2017

1 reference

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Automated genome mining for natural products.

22 September 2017

1 reference

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The biosynthetic logic of polyketide diversity

22 September 2017

1 reference

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ABySS: a parallel assembler for short read sequence data

22 September 2017

1 reference

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Natural products in crop protection

22 September 2017

1 reference

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Natural-product sugar biosynthesis and enzymatic glycodiversification

22 September 2017

1 reference

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In silico analysis of methyltransferase domains involved in biosynthesis of secondary metabolites

22 September 2017

1 reference

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Nonribosomal peptide synthetases involved in the production of medically relevant natural products

22 September 2017

1 reference

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Clustering millions of tandem mass spectra

22 September 2017

1 reference

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Polyketide synthases and nonribosomal peptide synthetases: the emerging view from bacterial genomics

22 September 2017

1 reference

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Phylogenetic analysis of condensation domains in NRPS sheds light on their functional evolution

22 September 2017

1 reference

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Natural products as sources of new drugs over the last 25 years

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598715

Identifying bacterial genes and endosymbiont DNA with Glimmer

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598715

Assembly-line enzymology for polyketide and nonribosomal Peptide antibiotics: logic, machinery, and mechanisms.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598715

Deciphering indolocarbazole and enediyne aminodideoxypentose biosynthesis through comparative genomics: insights from the AT2433 biosynthetic locus.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598715

Lessons from natural molecules

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598715

Chalcomycin biosynthesis gene cluster from Streptomyces bikiniensis: novel features of an unusual ketolide produced through expression of the chm polyketide synthase in Streptomyces fradiae

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598715

Enzymic activation and transfer of fatty acids as acyl-adenylates in mycobacteria

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598715

Antibiotic glycosyltransferases: antibiotic maturation and prospects for reprogramming

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598715

The Chemistry Development Kit (CDK): an open-source Java library for Chemo- and Bioinformatics

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598715

Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2)

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598715

Involvement of a cytochrome P450 monooxygenase in thaxtomin A biosynthesis by Streptomyces acidiscabies

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598715

A gene cluster for macrolide antibiotic biosynthesis in Streptomyces venezuelae: architecture of metabolic diversity

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598715

Cloning of genes governing the deoxysugar portion of the erythromycin biosynthesis pathway in Saccharopolyspora erythraea (Streptomyces erythreus)

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598715

antiSMASH 2.0--a versatile platform for genome mining of secondary metabolite producers

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598715

Nonribosomal assembly of natural lipocyclocarbamate lipoprotein-associated phospholipase inhibitors

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598715

Gold biomineralization by a metallophore from a gold-associated microbe.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598715

NRPSpredictor2--a web server for predicting NRPS adenylation domain specificity

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598715

Dereplication and de novo sequencing of nonribosomal peptides

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598715

Biosynthetic gene cluster of the glycopeptide antibiotic teicoplanin: characterization of two glycosyltransferases and the key acyltransferase

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598715

The gyrase inhibitor albicidin consists of p-aminobenzoic acids and cyanoalanine.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598715

NRPSsp: non-ribosomal peptide synthase substrate predictor

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598715

antiSMASH: rapid identification, annotation and analysis of secondary metabolite biosynthesis gene clusters in bacterial and fungal genome sequences

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598715

Biosynthetic gene cluster of the non-ribosomally synthesized cyclodepsipeptide skyllamycin: deciphering unprecedented ways of unusual hydroxylation reactions.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598715

ClustScan: an integrated program package for the semi-automatic annotation of modular biosynthetic gene clusters and in silico prediction of novel chemical structures

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598715

Structural elucidation studies of erythromycins by electrospray tandem mass spectrometry.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598715

Isolation, structure determination, and phytotoxicity of unusual dioxopiperazines from the phytopathogenic fungus Phoma lingam

20 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNCOMMS9421

Biological glycosidation of macrolide aglycones. I. Isolation and characterization of 5-O-mycaminosyl narbonolide and 9-dihydro-5-O-mycaminosyl narbonolide

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26412281

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NCOMMS9421

1 reference

21 September 2017

0 references

1 reference

21 September 2017

PubMed publication ID

26412281

1 reference