(Q42760942)

English

The M₁/M₄ preferring agonist xanomeline reverses amphetamine-, MK801- and scopolamine-induced abnormalities of latent inhibition: putative efficacy against positive, negative and cognitive symptoms in schizophrenia.

scientific article published on 7 January 2011

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21211109%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

The M₁/M₄ preferring agonist xanomeline reverses amphetamine-, MK801- and scopolamine-induced abnormalities of latent inhibition: putative efficacy against positive, negative and cognitive symptoms in schizophrenia (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21211109%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

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1

1 reference

Europe PubMed Central

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19 January 2020

author name string

Ina Weiner

2

1 reference

Europe PubMed Central

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19 January 2020

publication date

7 January 2011

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21211109%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

The International Journal of Neuropsychopharmacology

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21211109%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

14

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19 January 2020

9

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19 January 2020

1233-1246

1 reference

Europe PubMed Central

PubMed publication ID

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19 January 2020

Selective cognitive dysfunction in acetylcholine M1 muscarinic receptor mutant mice

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Pro-cognitive and antipsychotic efficacy of the alpha7 nicotinic partial agonist SSR180711 in pharmacological and neurodevelopmental latent inhibition models of schizophrenia.

1 reference

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Scopolamine induces disruption of latent inhibition which is prevented by antipsychotic drugs and an acetylcholinesterase inhibitor.

1 reference

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Differential role of muscarinic transmission within the entorhinal cortex and basolateral amygdala in the processing of irrelevant stimuli

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Dissociating scopolamine-induced disrupted and persistent latent inhibition: stage-dependent effects of glycine and physostigmine.

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Muscarinic receptors as a target for drugs treating schizophrenia

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Interactions between glutamatergic and monoaminergic systems within the basal ganglia-implications for schizophrenia and Parkinson's disease

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Allosteric modulation of the muscarinic M4 receptor as an approach to treating schizophrenia

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Central blockade of muscarinic cholinergic receptors disrupts affective and attentional set-shifting

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The relation between latent inhibition and symptom-types in young schizophrenics.

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Decreased muscarinic1 receptors in the dorsolateral prefrontal cortex of subjects with schizophrenia

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Elucidating the role of muscarinic receptors in psychosis

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Therapeutic strategies in Alzheimer's disease: M1 muscarinic agonists

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Cholinergic targets for cognitive enhancement in schizophrenia: focus on cholinesterase inhibitors and muscarinic agonists

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Abnormally persistent latent inhibition induced by MK801 is reversed by risperidone and by positive modulators of NMDA receptor function: differential efficacy depending on the stage of the task at which they are administered

1 reference

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Systemic administration of MK-801 produces an abnormally persistent latent inhibition which is reversed by clozapine but not haloperidol.

1 reference

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Enhancement of latent inhibition in patients with chronic schizophrenia.

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Hyperactivity, elevated dopaminergic transmission, and response to amphetamine in M1 muscarinic acetylcholine receptor-deficient mice

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Developing translational animal models for symptoms of schizophrenia or bipolar mania

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Enhancement of D1 dopamine receptor-mediated locomotor stimulation in M(4) muscarinic acetylcholine receptor knockout mice

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Dopaminergic modulation of limbic and cortical drive of nucleus accumbens in goal-directed behavior

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Phasic versus tonic dopamine release and the modulation of dopamine system responsivity: a hypothesis for the etiology of schizophrenia

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Latent inhibition: the nucleus accumbens connection revisited

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The pipeline and future of drug development in schizophrenia.

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Abolition of latent inhibition by a single 5 mg dose of d-amphetamine in man.

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Cholinergic modulation of basal and amphetamine-induced dopamine release in rat medial prefrontal cortex and nucleus accumbens

1 reference

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Amygdala regulation of nucleus accumbens dopamine output is governed by the prefrontal cortex.

1 reference

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Role of Receptor Protein and Membrane Lipids in Xanomeline Wash-Resistant Binding to Muscarinic M1Receptors

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Impaired inhibition of conditioned responses produced by subchronic administration of phencyclidine to rats

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Pharmacologic interactions between the muscarinic cholinergic and dopaminergic systems in the modulation of prepulse inhibition in rats

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Psychosis as a state of aberrant salience: a framework linking biology, phenomenology, and pharmacology in schizophrenia

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Subanesthetic effects of the noncompetitive NMDA antagonist, ketamine, in humans. Psychotomimetic, perceptual, cognitive, and neuroendocrine responses

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Effect of muscarinic receptor agonists xanomeline and sabcomeline on acetylcholine and dopamine efflux in the rat brain; comparison with effects of 4-[3-(4-butylpiperidin-1-yl)-propyl]-7-fluoro-4H-benzo[1,4]oxazin-3-one (AC260584) and N-desmethylclo

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Construct Validity of the Animal Latent Inhibition Model of Selective Attention Deficits in Schizophrenia

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1 reference

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1 reference

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1 reference

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1 reference

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The pharmacology of latent inhibition as an animal model of schizophrenia

1 reference

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1 reference

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1 reference

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7 January 2021

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1 reference

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1 reference

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7 January 2021

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1 reference

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1 reference

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7 January 2021

based on heuristic

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1 reference

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7 January 2021

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1 reference

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7 January 2021

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inferred from DOI database lookup

Selective muscarinic receptor agonist xanomeline as a novel treatment approach for schizophrenia

1 reference

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7 January 2021

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1 reference

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7 January 2021

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inferred from DOI database lookup

Linking animal models of psychosis to computational models of dopamine function.

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Scopolamine disrupts visual reversal without affecting the first discrimination

1 reference

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7 January 2021

based on heuristic

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N-desmethylclozapine, an allosteric agonist at muscarinic 1 receptor, potentiates N-methyl- d -aspartate receptor activity

1 reference

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7 January 2021

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1 reference

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7 January 2021

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1 reference

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1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Realistic expectations of prepulse inhibition in translational models for schizophrenia research

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Effects of nicotine and amphetamine on latent inhibition in human subjects

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

The NMDA-receptor antagonist MK-801 selectively disrupts reversal learning in rats

1 reference

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7 January 2021

based on heuristic

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Antagonism of amphetamine-induced disruption of latent inhibition in rats by haloperidol and ondansetron: implications for a possible antipsychotic action of ondansetron.

1 reference

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7 January 2021

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inferred from DOI database lookup

Functional effects of the muscarinic receptor agonist, xanomeline, at 5-HT1 and 5-HT2 receptors

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Neural substrates of latent inhibition: the switching model

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

The "two-headed" latent inhibition model of schizophrenia: modeling positive and negative symptoms and their treatment

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Using the pharmacology of latent inhibition to model domains of pathology in schizophrenia and their treatment

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Disruption of latent inhibition by acute administration of low doses of amphetamine.

1 reference

https://api.crossref.org/works/10.1017%2FS1461145710001549

7 January 2021

based on heuristic

inferred from DOI database lookup

Muscarinic acetylcholine receptors: mutant mice provide new insights for drug development

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Attenuation of amphetamine-induced activity by the non-selective muscarinic receptor agonist, xanomeline, is absent in muscarinic M4 receptor knockout mice and attenuated in muscarinic M1 receptor knockout mice

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

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1 reference

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