(Q42966822)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20639261%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

title

Incorporating human dosimetry and exposure into high-throughput in vitro toxicity screening (English)

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8 February 2020

7

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8 February 2020

David M. Reif

15

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8 February 2020

John F. Wambaugh

16

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8 February 2020

Russell S. Thomas

17

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8 February 2020

Daniel M Rotroff

1

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8 February 2020

Melvin E. Andersen

8

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8 February 2020

Richard S. Judson

9

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8 February 2020

Matthew T Martin

14

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8 February 2020

3

David J Dix

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8 February 2020

6

Keith A Houck

1 reference

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8 February 2020

2

Barbara A Wetmore

1 reference

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8 February 2020

11

Mark A Sochaski

1 reference

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8 February 2020

5

Harvey J Clewell

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8 February 2020

author name string

Stephen S Ferguson

4

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8 February 2020

Cornelia M Smith

10

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8 February 2020

Robert J Kavlock

12

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8 February 2020

Frank Boellmann

13

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8 February 2020

publication date

16 July 2010

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8 February 2020

published in

Toxicological Sciences

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8 February 2020

volume

117

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8 February 2020

issue

2

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8 February 2020

page(s)

348-358

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Toxicity testing in the 21st century: bringing the vision to life

8 February 2020

cites work

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFQ220

Comparative pharmacokinetics and bioavailability of oxolinic acid and oxytetracycline in rainbow trout (Oncorhynchus mykiss)

21 January 2018

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The integration of data on physico-chemical properties, in vitro-derived toxicity data and physiologically based kinetic and dynamic as modelling a tool in hazard and risk assessment. A commentary.

21 January 2018

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Biokinetic modeling and in vitro-in vivo extrapolations

21 January 2018

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The costs of REACH. REACH is largely welcomed, but the requirement to test existing chemicals for adverse effects is not good news for all.

21 January 2018

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https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFQ220

REACHing for chemical safety

21 January 2018

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ADME optimization and toxicity assessment in early- and late-phase drug discovery

21 January 2018

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Toxicity characterization of environmental chemicals by the US National Toxicology Program: an overview

21 January 2018

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Advancing exposure characterization for chemical evaluation and risk assessment.

21 January 2018

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Toxicology. Transforming environmental health protection

21 January 2018

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Physiologically based approaches towards the prediction of pharmacokinetics: in vitro-in vivo extrapolation

21 January 2018

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The ToxCast program for prioritizing toxicity testing of environmental chemicals

21 January 2018

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Concept of REACH and impact on evaluation of chemicals

21 January 2018

1 reference

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An approach for the quantitative consideration of genetic polymorphism data in chemical risk assessment: examples with warfarin and parathion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFQ220

Animal testing and alternative approaches for the human health risk assessment under the proposed new European chemicals regulation

21 January 2018

1 reference

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The Simcyp population-based ADME simulator

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFQ220

Substrate depletion approach for determining in vitro metabolic clearance: time dependencies in hepatocyte and microsomal incubations

21 January 2018

1 reference

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The toxicity data landscape for environmental chemicals

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFQ220

Toxicity testing in the 21st century: implications for human health risk assessment

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFQ220

Absorption and Excretion of 2,4-Dichlorophenoxyacetic Acid in Man

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFQ220

Profiling chemicals based on chronic toxicity results from the U.S. EPA ToxRef Database

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFQ220

Comparison of models for the estimation of biological partition coefficients

21 January 2018

1 reference

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Prediction of pharmacokinetics prior to in vivo studies. 1. Mechanism-based prediction of volume of distribution.

21 January 2018

1 reference

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Simulation and prediction of in vivo drug metabolism in human populations from in vitro data

21 January 2018

1 reference

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Clearance concepts in pharmacokinetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFQ220

Measured and estimated GFR in healthy potential kidney donors

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFQ220

The fate of 2,4-dichlorophenoxyacetic acid (2,4-D) following oral administration to man.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFQ220

Prediction of metabolic drug clearance in humans: in vitro-in vivo extrapolation vs allometric scaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFQ220

Prediction of in vivo embryotoxic effect levels with a combination of in vitro studies and PBPK modelling

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFQ220

Metabolism and kinetics of bisphenol a in humans at low doses following oral administration

21 January 2018

1 reference

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Validation of a rapid equilibrium dialysis approach for the measurement of plasma protein binding

21 January 2018

1 reference

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Toward a new U.S. chemicals policy: rebuilding the foundation to advance new science, green chemistry, and environmental health

21 January 2018

1 reference

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Toxicity Testing in the 21st Century: Implications for Human Health Risk Assessment

21 January 2018

1 reference

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Non-animal methodologies within biomedical research and toxicity testing

21 January 2018

1 reference

12 December 2020

Toxicity testing gets a makeover

1 reference

12 December 2020

Bioavailability of oxytetracycline, tetracycline and chlortetracycline after oral administration to fed and fasted pigs

1 reference

12 December 2020

Prediction of human clearance of twenty-nine drugs from hepatic microsomal intrinsic clearance data: An examination of in vitro half-life approach and nonspecific binding to microsomes.

1 reference

12 December 2020

Implementing the National Academy's Vision and Strategy for Toxicity Testing: opportunities and challenges under the U.S. Toxic Substances Control Act

1 reference

12 December 2020

Forum Series: the "Vision" for Toxicity Testing in the 21st Century: promises and conundrums

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12 December 2020

NTP-CERHR monograph on the potential human reproductive and developmental effects of bisphenol A.

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12 December 2020

In vitro screening of environmental chemicals for targeted testing prioritization: the ToxCast project

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12 December 2020

Cryopreserved human hepatocytes: characterization of drug-metabolizing enzyme activities and applications in higher throughput screening assays for hepatotoxicity, metabolic stability, and drug-drug interaction potential

1 reference

12 December 2020

Prediction of human hepatic clearance from in vivo animal experiments and in vitro metabolic studies with liver microsomes from animals and humans.

1 reference

12 December 2020

Identifiers

DOI

10.1093/TOXSCI/KFQ220

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20639261%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20639261%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

PubMed publication ID

20639261

1 reference