(Q43152628)

14 November 2017

title

Valproic acid induces antioxidant effects in X-linked adrenoleukodystrophy (English)

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14 November 2017

2

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6

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Cristina Guilera

3

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Stéphane Fourcade

Stéphane Fourcade

1

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Stephan Kemp

Stephan Kemp

11

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Jean-Louis Mandel

Jean Louis Mandel

12

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Ronald J A Wanders

10

Ronald Wanders

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14 November 2017

15

Patrick Aubourg

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14 November 2017

7

Manuel Portero-Otín

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14 November 2017

9

Nathalie Cartier

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14 November 2017

Eric Hahnen

4

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14 November 2017

Lars Brichta

5

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14 November 2017

Georges Dacremont

8

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Brunhilde Wirth

13

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14 November 2017

publication date

23 February 2010

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14 November 2017

published in

Human Molecular Genetics

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14 November 2017

volume

19

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14 November 2017

issue

10

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14 November 2017

page(s)

2005-2014

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Putative X-linked adrenoleukodystrophy gene shares unexpected homology with ABC transporters

14 November 2017

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Hematopoietic stem cell gene therapy with a lentiviral vector in X-linked adrenoleukodystrophy

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Valproic acid increases the SMN2 protein level: a well-known drug as a potential therapy for spinal muscular atrophy

21 January 2018

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In vitro and ex vivo evaluation of second-generation histone deacetylase inhibitors for the treatment of spinal muscular atrophy

21 January 2018

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A close relative of the adrenoleukodystrophy (ALD) gene codes for a peroxisomal protein with a specific expression pattern

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Adrenoleukodystrophy-related protein can compensate functionally for adrenoleukodystrophy protein deficiency (X-ALD): implications for therapy

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A key role for the peroxisomal ABCD2 transporter in fatty acid homeostasis.

21 January 2018

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Functional overlap between ABCD1 (ALD) and ABCD2 (ALDR) transporters: a therapeutic target for X-adrenoleukodystrophy

21 January 2018

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Late onset neurological phenotype of the X-ALD gene inactivation in mice: a mouse model for adrenomyeloneuropathy.

21 January 2018

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Phenylbutyrate up-regulates the adrenoleukodystrophy-related gene as a nonclassical peroxisome proliferator

21 January 2018

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X-linked adrenoleukodystrophy: very long-chain fatty acid metabolism, ABC half-transporters and the complicated route to treatment

21 January 2018

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The role of histone acetylation in SMN gene expression.

21 January 2018

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Endogenous alpha-synuclein is induced by valproic acid through histone deacetylase inhibition and participates in neuroprotection against glutamate-induced excitotoxicity.

21 January 2018

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Phase II open label study of valproic acid in spinal muscular atrophy

21 January 2018

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Valproic acid treatment in six patients with spinal muscular atrophy

21 January 2018

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Early oxidative damage underlying neurodegeneration in X-adrenoleukodystrophy

21 January 2018

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Suppression of peroxisomal membrane protein defects by peroxisomal ATP binding cassette (ABC) proteins

21 January 2018

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Decreased expression of ABCD4 and BG1 genes early in the pathogenesis of X-linked adrenoleukodystrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ082

Inhibition of histone deacetylase activity by valproic acid blocks adipogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ082

S-2-pentyl-4-pentynoic hydroxamic acid and its metabolite s-2-pentyl-4-pentynoic acid in the NMRI-exencephaly-mouse model: pharmacokinetic profiles, teratogenic effects, and histone deacetylase inhibition abilities of further valproic acid hydroxama

21 January 2018

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Histone deacetylase inhibitor valproic acid inhibits cancer cell proliferation via down-regulation of the alzheimer amyloid precursor protein

21 January 2018

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Adreno-leukodystrophy: oxidative stress of mice and men.

21 January 2018

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Oxidative imbalance in nonstimulated X-adrenoleukodystrophy-derived lymphoblasts

21 January 2018

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Maillard reaction products in tissue proteins: new products and new perspectives

21 January 2018

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Thyroid hormone induction of the adrenoleukodystrophy-related gene (ABCD2).

21 January 2018

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Molecular Species of Phosphatidylcholine Containing Very Long Chain Fatty Acids in Human Brain: Enrichment in X-Linked Adrenoleukodystrophy Brain and Diseases of Peroxisome Biogenesis Brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ082

Comparison of valproate concentrations in human plasma, CSF and brain tissue after administration of different formulations of valproate or valpromide

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ082

Survival motor neuron gene 2 silencing by DNA methylation correlates with spinal muscular atrophy disease severity and can be bypassed by histone deacetylase inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ082

A simple method for organotypic cultures of nervous tissue

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDQ082

A multiple-loop, double-cube microarray design applied to prostate cancer cell lines with variable sensitivity to histone deacetylase inhibitors

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDQ082

Fatty acid elongases in mammals: their regulation and roles in metabolism

21 January 2018

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Elongation of long-chain fatty acids

21 January 2018

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Role of Stargardt-3 macular dystrophy protein (ELOVL4) in the biosynthesis of very long chain fatty acids

21 January 2018

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Loss of functional ELOVL4 depletes very long-chain fatty acids (> or =C28) and the unique omega-O-acylceramides in skin leading to neonatal death

21 January 2018

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Steroid hormones control circadian Elovl3 expression in mouse liver.

21 January 2018

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Current hypotheses for the underlying biology of amyotrophic lateral sclerosis

21 January 2018

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Oxidative stress in Parkinson's disease: a mechanism of pathogenic and therapeutic significance

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ082

The effect of Lorenzo's oil on oxidative stress in X-linked adrenoleukodystrophy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ082

Elongation of very long-chain fatty acids is enhanced in X-linked adrenoleukodystrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ082

Common effects of lithium and valproate on mitochondrial functions: protection against methamphetamine-induced mitochondrial damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ082

Role of glutathione in neuroprotective effects of mood stabilizing drugs lithium and valproate.

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDQ082

Cytoprotection by lithium and valproate varies between cell types and cellular stresses

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ082

Oxidative stress as a mechanism of valproic acid-associated hepatotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ082

Carnitine in the treatment of valproic acid-induced toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ082

Suberoylanilide hydroxamic acid (SAHA) has potent anti-glioma properties in vitro, ex vivo and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ082

21 January 2018

Identifiers

DOI

10.1093/HMG/DDQ082

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14 November 2017

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