(Q43815493)

English

Importance of the amino-acid composition of the shutter region of plasminogen activator inhibitor-1 for its transitions to latent and substrate forms

scientific article published in December 2001

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

27 November 2017

Importance of the amino-acid composition of the shutter region of plasminogen activator inhibitor-1 for its transitions to latent and substrate forms (English)

1 reference

Europe PubMed Central

PubMed publication ID

27 November 2017

1 reference

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author name string

M Hansen

1

1 reference

Europe PubMed Central

PubMed publication ID

27 November 2017

M N Busse

2

1 reference

Europe PubMed Central

PubMed publication ID

27 November 2017

P A Andreasen

3

1 reference

Europe PubMed Central

PubMed publication ID

27 November 2017

language of work or name

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publication date

1 December 2001

1 reference

Europe PubMed Central

PubMed publication ID

27 November 2017

1 reference

Europe PubMed Central

PubMed publication ID

27 November 2017

268

1 reference

Europe PubMed Central

PubMed publication ID

27 November 2017

23

1 reference

Europe PubMed Central

PubMed publication ID

27 November 2017

6274-6283

1 reference

Europe PubMed Central

PubMed publication ID

27 November 2017

Implications of the three-dimensional structure of alpha 1-antitrypsin for structure and function of serpins

1 reference

https://api.crossref.org/works/10.1046%2FJ.0014-2956.2001.02582.X

21 January 2018

Phylogeny of the serpin superfamily: implications of patterns of amino acid conservation for structure and function.

1 reference

https://api.crossref.org/works/10.1046%2FJ.0014-2956.2001.02582.X

21 January 2018

The inhibition mechanism of serpins. Evidence that the mobile reactive center loop is cleaved in the native protease-inhibitor complex.

1 reference

https://api.crossref.org/works/10.1046%2FJ.0014-2956.2001.02582.X

21 January 2018

An ester bond linking a fragment of a serine proteinase to its serpin inhibitor.

1 reference

https://api.crossref.org/works/10.1046%2FJ.0014-2956.2001.02582.X

21 January 2018

A fluorescent probe study of plasminogen activator inhibitor-1. Evidence for reactive center loop insertion and its role in the inhibitory mechanism

1 reference

https://api.crossref.org/works/10.1046%2FJ.0014-2956.2001.02582.X

21 January 2018

Formation of the covalent serpin-proteinase complex involves translocation of the proteinase by more than 70 A and full insertion of the reactive center loop into beta-sheet A.

1 reference

https://api.crossref.org/works/10.1046%2FJ.0014-2956.2001.02582.X

21 January 2018

Structure of a serpin-protease complex shows inhibition by deformation

1 reference

https://api.crossref.org/works/10.1046%2FJ.0014-2956.2001.02582.X

21 January 2018

A serpin-induced extensive proteolytic susceptibility of urokinase-type plasminogen activator implicates distortion of the proteinase substrate-binding pocket and oxyanion hole in the serpin inhibitory mechanism

1 reference

https://api.crossref.org/works/10.1046%2FJ.0014-2956.2001.02582.X

21 January 2018

Partitioning of serpin-proteinase reactions between stable inhibition and substrate cleavage is regulated by the rate of serpin reactive center loop insertion into beta-sheet A.

1 reference

https://api.crossref.org/works/10.1046%2FJ.0014-2956.2001.02582.X

21 January 2018

Structural basis of latency in plasminogen activator inhibitor-1

1 reference

https://api.crossref.org/works/10.1046%2FJ.0014-2956.2001.02582.X

21 January 2018

Serpin tertiary structure transformation

1 reference

https://api.crossref.org/works/10.1046%2FJ.0014-2956.2001.02582.X

21 January 2018

The crystal structure of plasminogen activator inhibitor 2 at 2.0 A resolution: implications for serpin function

1 reference

https://api.crossref.org/works/10.1046%2FJ.0014-2956.2001.02582.X

21 January 2018

What do dysfunctional serpins tell us about molecular mobility and disease?

1 reference

https://api.crossref.org/works/10.1046%2FJ.0014-2956.2001.02582.X

21 January 2018

Familial dementia caused by polymerization of mutant neuroserpin

1 reference

https://api.crossref.org/works/10.1046%2FJ.0014-2956.2001.02582.X

21 January 2018

Role of Lys335 in the metastability and function of inhibitory serpins

1 reference

https://api.crossref.org/works/10.1046%2FJ.0014-2956.2001.02582.X

21 January 2018

Plasminogen activator inhibitor type-1: reactive center and amino-terminal heterogeneity determined by protein and cDNA sequencing.

1 reference

https://api.crossref.org/works/10.1046%2FJ.0014-2956.2001.02582.X

21 January 2018

Analysis of mutation in human cells by using an Epstein-Barr virus shuttle system

1 reference

https://api.crossref.org/works/10.1046%2FJ.0014-2956.2001.02582.X

21 January 2018

Interconversions between active, inert and substrate forms of denatured/refolded type-1 plasminogen activator inhibitor

1 reference

https://api.crossref.org/works/10.1046%2FJ.0014-2956.2001.02582.X

21 January 2018

Localization of epitopes for monoclonal antibodies to urokinase-type plasminogen activator: relationship between epitope localization and effects of antibodies on molecular interactions of the enzyme

1 reference

https://api.crossref.org/works/10.1046%2FJ.0014-2956.2001.02582.X

21 January 2018

SWISS-MODEL and the Swiss-PdbViewer: an environment for comparative protein modeling

1 reference

https://api.crossref.org/works/10.1046%2FJ.0014-2956.2001.02582.X

21 January 2018

Plasminogen activator inhibitor 1. Structure of the native serpin, comparison to its other conformers and implications for serpin inactivation

1 reference

https://api.crossref.org/works/10.1046%2FJ.0014-2956.2001.02582.X

21 January 2018

A substrate-like form of plasminogen-activator-inhibitor type 1. Conversions between different forms by sodium dodecyl sulphate

1 reference

https://api.crossref.org/works/10.1046%2FJ.0014-2956.2001.02582.X

21 January 2018

Mechanisms contributing to the conformational and functional flexibility of plasminogen activator inhibitor-1

1 reference

https://api.crossref.org/works/10.1046%2FJ.0014-2956.2001.02582.X

21 January 2018

Extending the capabilities of targeted molecular dynamics: simulation of a large conformational transition in plasminogen activator inhibitor 1.

1 reference

https://api.crossref.org/works/10.1046%2FJ.0014-2956.2001.02582.X

21 January 2018

The active conformation of plasminogen activator inhibitor 1, a target for drugs to control fibrinolysis and cell adhesion

1 reference

https://api.crossref.org/works/10.1046%2FJ.0014-2956.2001.02582.X

21 January 2018

Structures of active and latent PAI-1: a possible stabilizing role for chloride ions

1 reference

https://api.crossref.org/works/10.1046%2FJ.0014-2956.2001.02582.X

21 January 2018

The urokinase-type plasminogen activator system in cancer metastasis: a review

1 reference

https://api.crossref.org/works/10.1046%2FJ.0014-2956.2001.02582.X

21 January 2018

The plasminogen activation system in tumor growth, invasion, and metastasis

1 reference

https://api.crossref.org/works/10.1046%2FJ.0014-2956.2001.02582.X

21 January 2018

Identification of the binding site for a low-molecular-weight inhibitor of plasminogen activator inhibitor type 1 by site-directed mutagenesis

1 reference

https://api.crossref.org/works/10.1046%2FJ.0014-2956.2001.02582.X

21 January 2018

Epitope mapping for four monoclonal antibodies against human plasminogen activator inhibitor type-1: implications for antibody-mediated PAI-1-neutralization and vitronectin-binding

1 reference

https://api.crossref.org/works/10.1046%2FJ.0014-2956.2001.02582.X

21 January 2018

A regulatory hydrophobic area in the flexible joint region of plasminogen activator inhibitor-1, defined with fluorescent activity-neutralizing ligands. Ligand-induced serpin polymerization

1 reference

https://api.crossref.org/works/10.1046%2FJ.0014-2956.2001.02582.X

21 January 2018

Serpin-protease complexes are trapped as stable acyl-enzyme intermediates

1 reference

https://api.crossref.org/works/10.1046%2FJ.0014-2956.2001.02582.X

21 January 2018

The structure of a serpin-protease complex revealed by intramolecular distance measurements using donor-donor energy migration and mapping of interaction sites

1 reference

https://api.crossref.org/works/10.1046%2FJ.0014-2956.2001.02582.X

21 January 2018

Engineering of conformations of plasminogen activator inhibitor-1. A crucial role of beta-strand 5A residues in the transition of active form to latent and substrate forms

1 reference

https://api.crossref.org/works/10.1046%2FJ.0014-2956.2001.02582.X

21 January 2018

Conformational changes of the reactive-centre loop and beta-strand 5A accompany temperature-dependent inhibitor-substrate transition of plasminogen-activator inhibitor 1

1 reference

https://api.crossref.org/works/10.1046%2FJ.0014-2956.2001.02582.X

21 January 2018

Metastability in the inhibitory mechanism of human alpha1-antitrypsin

1 reference

https://api.crossref.org/works/10.1046%2FJ.0014-2956.2001.02582.X

21 January 2018

Type-1 inhibitor of plasminogen activators. Distinction between latent, activated and reactive centre-cleaved forms with thermal stability and monoclonal antibodies

1 reference

https://api.crossref.org/works/10.1046%2FJ.0014-2956.2001.02582.X

21 January 2018

Identification of positively charged residues contributing to the stability of plasminogen activator inhibitor 1

1 reference

https://api.crossref.org/works/10.1046%2FJ.0014-2956.2001.02582.X

21 January 2018

Neutralization of plasminogen activator inhibitor-1 inhibitory properties: identification of two different mechanisms

1 reference

https://api.crossref.org/works/10.1046%2FJ.0014-2956.2001.02582.X

21 January 2018

Identifiers

10.1046/J.0014-2956.2001.02582.X

1 reference

Europe PubMed Central

PubMed publication ID

27 November 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

27 November 2017

ResearchGate publication ID

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