(Q45880920)

17 December 2017

title

Inhibitors of apoptosis confer resistance to tumour suppression by adoptively transplanted cytotoxic T-lymphocytes in vitro and in vivo (English)

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17 December 2017

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Huber C

1

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17 December 2017

Bobek N

2

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17 December 2017

Kuball J

3

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17 December 2017

Thaler S

4

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17 December 2017

Hoffarth S

5

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17 December 2017

Huber C

6

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17 December 2017

Theobald M

7

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17 December 2017

Schuler M

8

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17 December 2017

language of work or name

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1 April 2005

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17 December 2017

Cell Death & Differentiation

published in

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17 December 2017

volume

12

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17 December 2017

issue

4

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17 December 2017

page(s)

317-325

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17 December 2017

https://scigraph.springernature.com/pub.10.1038/sj.cdd.4401563

exact match

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cites work

The Hallmarks of Cancer

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401563

7 January 2021

The RB and p53 pathways in cancer

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401563

7 January 2021

A matter of life and death

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401563

7 January 2021

Disruption of the ARF-Mdm2-p53 tumor suppressor pathway in Myc-induced lymphomagenesis

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401563

7 January 2021

INK4a/ARF mutations accelerate lymphomagenesis and promote chemoresistance by disabling p53.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401563

7 January 2021

Novel primitive lymphoid tumours induced in transgenic mice by cooperation between myc and bcl-2.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401563

7 January 2021

Bax loss impairs Myc-induced apoptosis and circumvents the selection of p53 mutations during Myc-mediated lymphomagenesis

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401563

7 January 2021

Dissecting p53 tumor suppressor functions in vivo

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401563

7 January 2021

p53-dependent apoptosis modulates the cytotoxicity of anticancer agents

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401563

7 January 2021

Ionizing radiation and chemotherapeutic drugs induce apoptosis in lymphocytes in the absence of Fas or FADD/MORT1 signaling. Implications for cancer therapy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401563

7 January 2021

Alterations in the apoptotic machinery and their potential role in anticancer drug resistance

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401563

7 January 2021

Cytolytic T-cell cytotoxicity is mediated through perforin and Fas lytic pathways

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401563

7 January 2021

Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin-deficient mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401563

7 January 2021

Cytotoxic lymphocytes require granzyme B for the rapid induction of DNA fragmentation and apoptosis in allogeneic target cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401563

7 January 2021

Cleaving the oxidative repair protein Ape1 enhances cell death mediated by granzyme A

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401563

7 January 2021

Tumor suppressor NM23-H1 is a granzyme A-activated DNase during CTL-mediated apoptosis, and the nucleosome assembly protein SET is its inhibitor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401563

7 January 2021

BCL-2, BCL-X(L) sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401563

7 January 2021

Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401563

7 January 2021

A dominant interfering mutant of FADD/MORT1 enhances deletion of autoreactive thymocytes and inhibits proliferation of mature T lymphocytes

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401563

7 January 2021

Ubiquitin protein ligase activity of IAPs and their degradation in proteasomes in response to apoptotic stimuli

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401563

7 January 2021

Targeting p53 as a general tumor antigen

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401563

7 January 2021

The Bcl2 family: regulators of the cellular life-or-death switch

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401563

7 January 2021

Granzyme B-mediated cytochrome c release is regulated by the Bcl-2 family members bid and Bax.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401563

7 January 2021

Initiation of apoptosis by granzyme B requires direct cleavage of bid, but not direct granzyme B-mediated caspase activation.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401563

7 January 2021

Granzyme B-mediated apoptosis proceeds predominantly through a Bcl-2-inhibitable mitochondrial pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401563

7 January 2021

Transgenic overexpression of human Bcl-2 in islet β cells inhibits apoptosis but does not prevent autoimmune destruction

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401563

7 January 2021

bax-deficiency promotes drug resistance and oncogenic transformation by attenuating p53-dependent apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401563

7 January 2021

PUMA, a novel proapoptotic gene, is induced by p53

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401563

7 January 2021

p53- and drug-induced apoptotic responses mediated by BH3-only proteins puma and noxa

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401563

7 January 2021

p53 triggers apoptosis in oncogene-expressing fibroblasts by the induction of Noxa and mitochondrial Bax translocation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401563

7 January 2021

Involvement of the bcl-2 gene in human follicular lymphoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401563

7 January 2021

Somatic frameshift mutations in the BAX gene in colon cancers of the microsatellite mutator phenotype.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401563

7 January 2021

A caspase-9 variant missing the catalytic site is an endogenous inhibitor of apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401563

7 January 2021

Impaired BAX protein expression in breast cancer: mutational analysis of the BAX and the p53 gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401563

7 January 2021

Defective cytochrome c-dependent caspase activation in ovarian cancer cell lines due to diminished or absent apoptotic protease activating factor-1 activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401563

7 January 2021

Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401563

7 January 2021

Two CD95 (APO-1/Fas) signaling pathways

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401563

7 January 2021

Lethal effect of the anti-Fas antibody in mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401563

7 January 2021

Apoptosis induced in normal human hepatocytes by tumor necrosis factor-related apoptosis-inducing ligand

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401563

7 January 2021

Caspase activation by granzyme B is indirect, and caspase autoprocessing requires the release of proapoptotic mitochondrial factors.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401563

7 January 2021

Granzyme B-induced apoptosis requires both direct caspase activation and relief of caspase inhibition

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401563

7 January 2021

Apaf-1 and caspase-9 do not act as tumor suppressors in myc-induced lymphomagenesis or mouse embryo fibroblast transformation.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401563

7 January 2021

Apaf-1 and caspase-9 accelerate apoptosis, but do not determine whether factor-deprived or drug-treated cells die

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401563

7 January 2021

Apoptotic protease activating factor 1 (Apaf-1)-independent cell death suppression by Bcl-2.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401563

7 January 2021

Inhibition of death receptor signals by cellular FLIP

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401563

7 January 2021

Immune escape of tumors in vivo by expression of cellular FLICE-inhibitory protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401563

7 January 2021

Blockade of the granzyme B/perforin pathway through overexpression of the serine protease inhibitor PI-9/SPI-6 constitutes a mechanism for immune escape by tumors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401563

7 January 2021

Tumor eradication by wild-type p53-specific cytotoxic T lymphocytes.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401563

7 January 2021

Eradication of established tumors by CD8+ T cell adoptive immunotherapy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401563

7 January 2021

Identification of small-molecule inhibitors of interaction between the BH3 domain and Bcl-xL

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401563

7 January 2021

Activation of apoptosis in vivo by a hydrocarbon-stapled BH3 helix

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401563

7 January 2021

Smac agonists sensitize for Apo2L/TRAIL- or anticancer drug-induced apoptosis and induce regression of malignant glioma in vivo.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401563

7 January 2021

Small-molecule antagonists of apoptosis suppressor XIAP exhibit broad antitumor activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401563

7 January 2021

Tolerance to p53 by A2.1-restricted cytotoxic T lymphocytes.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401563

7 January 2021

Identifiers

DOI

10.1038/SJ.CDD.4401563

1 reference

17 December 2017

Dimensions Publication ID

0 references

1 reference

17 December 2017