(Q46259086)

20 December 2017

title

The heterotrimeric G-protein alpha-subunit Galphaq regulates TCR-mediated immune responses through an Lck-dependent pathway (English)

1 reference

20 December 2017

Nina Wettschureck

7

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Kjetil Taskén

object named as

Kjetil Taskén

8

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author name string

Jacob Ngai

1

1 reference

20 December 2017

Trond Methi

2

1 reference

20 December 2017

Kjetil Wessel Andressen

3

1 reference

20 December 2017

Finn Olav Levy

4

1 reference

20 December 2017

Knut Martin Torgersen

5

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20 December 2017

Torkel Vang

6

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20 December 2017

language of work or name

English

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publication date

1 November 2008

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20 December 2017

European Journal of Immunology

published in

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20 December 2017

volume

38

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20 December 2017

issue

11

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20 December 2017

page(s)

3208-3218

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20 December 2017

Superantigen stimulation reveals the contribution of Lck to negative regulation of T cell activation.

cites work

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838195

Short-interfering RNA-mediated Lck knockdown results in augmented downstream T cell responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838195

TCR- and CD28-mediated recruitment of phosphodiesterase 4 to lipid rafts potentiates TCR signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838195

The potency of TCR signaling differentially regulates NFATc/p activity and early IL-4 transcription in naive CD4+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838195

Dynamics of proximal signaling events after TCR/CD8-mediated induction of proliferation or apoptosis in mature CD8+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838195

The T cell receptor: critical role of the membrane environment in receptor assembly and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838195

7 January 2021

Full Activation of the T Cell Receptor Requires Both Clustering and Conformational Changes at CD3

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838195

7 January 2021

T-cell receptor signal transmission: who gives an ITAM?

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838195

7 January 2021

The zeta chain is associated with a tyrosine kinase and upon T-cell antigen receptor stimulation associates with ZAP-70, a 70-kDa tyrosine phosphoprotein

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838195

7 January 2021

LAT: the ZAP-70 tyrosine kinase substrate that links T cell receptor to cellular activation

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838195

7 January 2021

Function of the Src-family kinases, Lck and Fyn, in T-cell development and activation

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838195

7 January 2021

The tyrosine kinase Lck is a positive regulator of the mitochondrial apoptosis pathway by controlling Bak expression

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838195

7 January 2021

The role of CD4-Lck in T-cell receptor antagonism: evidence for negative signaling

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838195

7 January 2021

Hypophosphorylated TCR/CD3zeta signals through a Grb2-SOS1-Ras pathway in Lck knockdown cells

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838195

7 January 2021

Mammalian G proteins and their cell type specific functions

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838195

7 January 2021

Role of c-Src tyrosine kinase in G protein-coupled receptor- and Gbetagamma subunit-mediated activation of mitogen-activated protein kinases

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838195

7 January 2021

Regulation of tyrosine kinase cascades by G-protein-coupled receptors.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838195

7 January 2021

Not so strange bedfellows: G-protein-coupled receptors and Src family kinases

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838195

7 January 2021

Apoptotic Signaling through the β-Adrenergic Receptor

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838195

7 January 2021

Src tyrosine kinase is a novel direct effector of G proteins.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838195

7 January 2021

CXCR4 physically associates with the T cell receptor to signal in T cells

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838195

7 January 2021

Lck is required for stromal cell-derived factor 1 alpha (CXCL12)-induced lymphoid cell chemotaxis

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838195

7 January 2021

Positive regulation of human T cell activation by Gi2 proteins and interleukin-8

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838195

7 January 2021

Interaction between G proteins and tyrosine kinases upon T cell receptor.CD3-mediated signaling

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838195

7 January 2021

Normal hematopoiesis and inflammatory responses despite discrete signaling defects in Galpha15 knockout mice

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838195

7 January 2021

The Cbl family proteins: ring leaders in regulation of cell signaling

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838195

7 January 2021

c-Cbl and Cbl-b ubiquitin ligases: substrate diversity and the negative regulation of signalling responses

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838195

7 January 2021

Gq signaling is required for allergen-induced pulmonary eosinophilia

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838195

7 January 2021

Reduced Cbl phosphorylation and degradation of the zeta-chain of the T-cell receptor/CD3 complex in T cells with low Lck levels

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838195

7 January 2021

Bacterial Superantigens Bypass Lck-Dependent T Cell Receptor Signaling by Activating a Gα11-Dependent, PLC-β-Mediated Pathway

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838195

7 January 2021

Phosphoinositide 3-kinase gamma participates in T cell receptor-induced T cell activation.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838195

7 January 2021

Activated Gαq Inhibits p110α Phosphatidylinositol 3-Kinase and Akt

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838195

7 January 2021

The p110gamma isoform of phosphatidylinositol 3-kinase regulates migration of effector CD4 T lymphocytes into peripheral inflammatory sites.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838195

7 January 2021

T cell costimulation by chemokine receptors

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838195

7 January 2021

Signal transduction by the TCR for antigen

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838195

7 January 2021

T cell receptor for antigen induces linker for activation of T cell-dependent activation of a negative signaling complex involving Dok-2, SHIP-1, and Grb-2

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838195

7 January 2021

Roles of the SHP-1 tyrosine phosphatase in the negative regulation of cell signalling

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838195

7 January 2021

Stromal cell-derived factor-1alpha/CXCL12-induced chemotaxis of T cells involves activation of the RasGAP-associated docking protein p62Dok-1.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838195

7 January 2021

Fyn, Yes, and Syk phosphorylation sites in c-Cbl map to the same tyrosine residues that become phosphorylated in activated T cells

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838195

7 January 2021

Regulation of T cell activation, anxiety, and male aggression by RGS2.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838195

7 January 2021

Lck activity controls CD4/CD8 T cell lineage commitment.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838195

7 January 2021

Defective platelet activation in G alpha(q)-deficient mice.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838195

7 January 2021

Identifiers

DOI

10.1002/EJI.200838195

1 reference

20 December 2017

1 reference

20 December 2017